MED27

General Information

Gene Name       : MED27
Gene ID             : ENSG00000160563.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MED27)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MED27ENSG00000160563.1314.1718.7716.47ENCSR000AEF
HepG2MED27ENSG00000160563.1318.7915.8717.33ENCSR985KAT
K562MED27ENSG00000160563.1331.1229.9330.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MED27 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MED27 RNA is bound by 11 proteins.  







eCLIP assay for MED27 is not avaliable on ENCORE database.





11 proteins are bound to MED27 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9134735717134735824-3'-UTR,intron-Distal3.659906.00726K562YBX3
chr9134738449134738496-CDS,intron-Distal,intron-Proximal3.217534.11795K562YBX3
chr9134849603134849716-intron-Distal5.066966.58335HepG2QKI
chr9134810411134810504-intron-Distal4.439564.05848HepG2QKI
chr9134946680134946762-intron-Distal4.365154.62276K562TARDBP
chr9134839909134839947-intron-Distal5.000125.63362K562AGGF1
chr9134845793134845850-intron-Distal3.944134.80898K562HNRNPM
chr9134839702134839751-intron-Distal4.294394.87455HepG2AGGF1
chr9134883673134883725-intron-Distal3.958653.27946HepG2HNRNPM
chr9134810379134810513-intron-Distal3.706335.98064K562QKI
chr9134839642134839823-intron-Distal5.7571810.00393HepG2HNRNPL
chr9134849584134849709-intron-Distal5.788659.99398K562QKI
chr9134766224134766312-intron-Distal5.2353116.02742HepG2QKI
chr9134916888134916980-intron-Distal6.0517522.96718HepG2DKC1
chr9134766228134766346-intron-Distal5.293277.90406K562QKI
chr9134916418134916498-intron-Distal4.656724.03269HepG2PTBP1
chr9134776279134776492-intron-Distal5.306389.00303HepG2PCBP2
chr9134947133134947185-intron-Distal4.112424.13603K562TARDBP
chr9134946861134946924-intron-Distal5.061489.32163K562TARDBP
chr9134916407134916510-intron-Distal5.9787110.98212K562PTBP1
chr9134839635134839702-intron-Distal6.5726420.34004K562AGGF1
chr9134947387134947468-intron-Distal4.704635.44904K562TARDBP
chr9134839436134839467-intron-Distal3.929385.31527K562AGGF1
chr9134756781134756843-intron-Distal4.518184.57427HepG2PCBP2
chr9134947378134947482-intron-Distal3.940735.23268K562EIF4G2
chr9134947323134947368-intron-Distal3.926443.34609K562TARDBP
chr9134947185134947259-intron-Distal4.940987.89429K562TARDBP
chr9134944221134944307-intron-Distal3.436304.08528HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MED27 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MED27 is not available on ENCORE database.

  • 43 RBPs can affect the levels of MED27.  








The Knockdown/knockout RNA-Seq assay for MED27 is not available on ENCORE database.





43 RBPs can affect the gene expression of MED27 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MED27ENSG00000160563.9308.19280213.442800.529903.324402.66760HepG2ACO1
MED27ENSG00000160563.9536.64300270.193400.989907.747806.90560HepG2AKAP1
MED27ENSG00000160563.9309.16430223.556300.467602.003601.33130HepG2ASCC1
MED27ENSG00000160563.9414.89670246.420100.751505.603104.78770HepG2BOP1
MED27ENSG00000160563.9269.18020135.530800.989904.788103.77610HepG2CNOT7
MED27ENSG00000160563.9114.98280226.22690-0.976405.179404.26450HepG2CPSF6
MED27ENSG00000160563.9438.72480258.811800.761305.153504.32340HepG2DDX3X
MED27ENSG00000160563.9115.40950256.89740-1.154405.352104.00500HepG2DDX59
MED27ENSG00000160563.9334.89340238.336900.490602.246701.62090HepG2FXR1
MED27ENSG00000160563.9203.81480139.773500.544102.117701.33860HepG2GEMIN5
MED27ENSG00000160563.9123.21800195.63340-0.666902.611501.62450HepG2GNB2L1
MED27ENSG00000160563.9163.97310256.44530-0.645202.785202.14230HepG2GPKOW
MED27ENSG00000160563.9314.19530223.907100.488702.193001.56540HepG2HNRNPK
MED27ENSG00000160563.9332.72110224.703500.566202.837802.15540HepG2IGF2BP2
MED27ENSG00000160563.9400.32930239.747500.739604.311903.54090HepG2MATR3
MED27ENSG00000160563.9145.69040217.00080-0.574802.175701.51020HepG2NSUN2
MED27ENSG00000160563.9297.99630226.178600.397701.909201.43860HepG2PTBP1
MED27ENSG00000160563.9460.56720360.980300.351402.065501.60020HepG2RBM22
MED27ENSG00000160563.9172.59910242.23460-0.489001.894801.30290HepG2SF3B1
MED27ENSG00000160563.9109.54120269.52850-1.299007.112805.85550HepG2SNRNP70
MED27ENSG00000160563.9523.74200407.706400.361202.514802.02920HepG2SRFBP1
MED27ENSG00000160563.9411.52060245.791100.743406.369005.72360HepG2SRSF1
MED27ENSG00000160563.9408.05150322.998300.337101.896201.36350HepG2SUCLG1
MED27ENSG00000160563.9382.54050278.596000.457301.931401.39560HepG2U2AF1
MED27ENSG00000160563.9380.65340269.047000.500501.813001.34480HepG2ZNF622
MED27ENSG00000160563.9705.68800540.331900.385102.562201.93290K562AKAP8L
MED27ENSG00000160563.9734.48900566.931600.373503.089902.12170K562ATP5C1
MED27ENSG00000160563.9372.33910530.58530-0.511003.717302.80910K562CPSF6
MED27ENSG00000160563.91048.68920862.886700.281202.605501.97090K562DDX47
MED27ENSG00000160563.9854.68210581.457500.555606.870605.38630K562DKC1
MED27ENSG00000160563.9462.96320279.736700.726706.923505.67550K562EIF3G
MED27ENSG00000160563.9883.414301105.88710-0.324002.975502.00350K562EIF4G2
MED27ENSG00000160563.9310.75150457.62810-0.558403.257002.25820K562FTO
MED27ENSG00000160563.9652.42180414.445000.654507.461606.53220K562FXR1
MED27ENSG00000160563.9478.64520677.85540-0.502004.360903.01590K562HNRNPA1
MED27ENSG00000160563.9601.82790402.658200.579704.117502.56970K562HNRNPK
MED27ENSG00000160563.9852.83520609.108100.485503.321902.29430K562HNRNPM
MED27ENSG00000160563.9299.73010432.58320-0.529302.496201.61240K562KRR1
MED27ENSG00000160563.9603.62340411.716700.551902.864602.19040K562PTBP1
MED27ENSG00000160563.91038.202901283.35390-0.305802.544401.52290K562PUM1
MED27ENSG00000160563.91030.892001257.50620-0.286702.414701.51580K562PUM2
MED27ENSG00000160563.9774.87840535.885800.531902.887802.33540K562PUS1
MED27ENSG00000160563.9728.72420522.119400.480904.466703.73200K562RBM15
MED27ENSG00000160563.9622.78030441.764300.495302.822601.99740K562RPS19
MED27ENSG00000160563.9574.39970403.639000.508903.889603.05730K562SRSF1
MED27ENSG00000160563.9675.98540971.58550-0.523304.488502.70870K562SSRP1
MED27ENSG00000160563.9458.85910627.20020-0.450903.507802.52420K562WDR3
MED27ENSG00000160563.9767.869001007.36880-0.391703.191002.25640K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MED27 is not available on ENCORE database.





4 RBPs can affect the splicing of MED27 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMED27ENSG00000160563.9chr9-1347445701347447711347384491347385271347594441347594860.064000.000740.00950includedK562AQR
SEMED27ENSG00000160563.9chr9-134889723134889854134814767134814861134952828134952973-0.064000.000030.00063excludedK562AQR
A3SSMED27ENSG00000160563.9chr9-1347692711347694581347692711347693791348147671348148910.053000.000000.00000longerK562AQR
A3SSMED27ENSG00000160563.9chr9-1349528281349530031349528281349529731349550281349552530.052000.000010.00006longerK562AQR
MXEMED27ENSG00000160563.9chr9-134759444134759486134769271134769379134738449134738527134814767134814861-0.186000.001330.022352includedK562DROSHA
MXEMED27ENSG00000160563.9chr9-1347594441347594861348147671348148911347384491347385271349528281349529730.064000.000470.004711includedK562AQR
MXEMED27ENSG00000160563.9chr9-1347594441347594861347692711347694041347384491347385271348147671348148610.055000.000050.000641includedK562AQR
MXEMED27ENSG00000160563.9chr9-1347692711347693791348147671348148611347594441347594861349528281349529730.142000.011620.071501includedK562AQR
MXEMED27ENSG00000160563.9chr9-134759444134759486134769271134769379134738449134738527134814767134814861-0.138000.019870.092172includedHepG2U2AF2
MXEMED27ENSG00000160563.9chr9-134759444134759486134769271134769379134738449134738527134814767134814861-0.141000.000080.005522includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MED27 is not avaliable on ENCORE database.