DET1

General Information

Gene Name       : DET1
Gene ID             : ENSG00000140543.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DET1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DET1ENSG00000140543.140.461.040.75ENCSR000AEF
HepG2DET1ENSG00000140543.141.512.121.81ENCSR985KAT
K562DET1ENSG00000140543.145.034.904.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DET1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DET1 RNA is bound by 1 proteins.  







eCLIP assay for DET1 is not avaliable on ENCORE database.





1 proteins are bound to DET1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr158906001589060075-3'-UTR,CDS,intron-Distal3.202103.02345K562ZNF622
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DET1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DET1 is not available on ENCORE database.

  • 43 RBPs can affect the levels of DET1.  








The Knockdown/knockout RNA-Seq assay for DET1 is not available on ENCORE database.





43 RBPs can affect the gene expression of DET1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DET1ENSG00000140543.9110.48360165.02700-0.578902.396201.74860HepG2AUH
DET1ENSG00000140543.9188.5799075.075401.328706.206805.06090HepG2CNOT7
DET1ENSG00000140543.9150.2095066.892401.167005.340704.41480HepG2CPSF6
DET1ENSG00000140543.968.15200155.90370-1.193805.327304.48430HepG2DDX3X
DET1ENSG00000140543.967.24240133.90070-0.993703.402002.72500HepG2DDX6
DET1ENSG00000140543.973.59170147.79550-1.006004.026003.26720HepG2NCBP2
DET1ENSG00000140543.920.0008068.65220-1.779204.031602.94680HepG2PABPC1
DET1ENSG00000140543.979.98960129.94050-0.700002.606402.01270HepG2PCBP1
DET1ENSG00000140543.964.00910119.13310-0.896202.966301.89250HepG2PCBP2
DET1ENSG00000140543.9134.7429075.489000.835802.788301.98580HepG2RPS3A
DET1ENSG00000140543.976.79770124.48910-0.696901.944301.37670HepG2SF3A3
DET1ENSG00000140543.9115.6955071.631900.691602.030201.42060HepG2SF3B1
DET1ENSG00000140543.9101.12850178.87340-0.822704.320503.73440HepG2SRFBP1
DET1ENSG00000140543.986.77740143.68480-0.727502.731202.26060HepG2SRSF1
DET1ENSG00000140543.9160.8890095.445800.753203.000502.28020HepG2SRSF7
DET1ENSG00000140543.9242.06490155.292000.640301.871601.42840HepG2SSB
DET1ENSG00000140543.942.2270078.29950-0.890802.039101.44550HepG2SUPV3L1
DET1ENSG00000140543.986.95700129.13740-0.570501.954901.46950HepG2TAF15
DET1ENSG00000140543.942.05900103.66800-1.301504.119003.35920HepG2U2AF1
DET1ENSG00000140543.9158.75440322.52600-1.022608.966508.02060K562AGGF1
DET1ENSG00000140543.9190.08000354.39550-0.898807.305005.51220K562AKAP8
DET1ENSG00000140543.9127.57620335.60000-1.3954013.5478011.93720K562AKAP8L
DET1ENSG00000140543.9192.64530352.11970-0.870107.679006.03920K562ATP5C1
DET1ENSG00000140543.9270.18180385.44560-0.512603.389902.06630K562CCDC124
DET1ENSG00000140543.9299.09800175.239300.771203.201002.04580K562CNOT7
DET1ENSG00000140543.9262.08540378.41100-0.529903.161401.59230K562DDX19B
DET1ENSG00000140543.9190.67750361.14770-0.921508.795807.06570K562DKC1
DET1ENSG00000140543.9192.91780120.055900.684203.255902.60840K562FXR1
DET1ENSG00000140543.9214.64600147.305000.543102.197001.65620K562HNRNPC
DET1ENSG00000140543.9360.97290243.626800.567103.626002.39280K562HNRNPL
DET1ENSG00000140543.9134.02090356.16560-1.4101014.7224012.28200K562KIF1C
DET1ENSG00000140543.9146.55970340.92990-1.218009.602907.21020K562MAK16
DET1ENSG00000140543.9240.10500165.982900.532502.621601.72500K562MATR3
DET1ENSG00000140543.9191.25360398.99400-1.0609010.565408.58770K562MBNL1
DET1ENSG00000140543.9109.34150279.66500-1.354908.436706.55960K562NAA15
DET1ENSG00000140543.969.08100147.98230-1.099104.944003.62620K562PCBP2
DET1ENSG00000140543.9313.84630197.741400.666303.412002.48750K562PCBP3
DET1ENSG00000140543.9216.79060151.671000.515302.302901.57250K562POLR2G
DET1ENSG00000140543.999.15700332.84380-1.7471017.2509015.93760K562PUS1
DET1ENSG00000140543.9105.41850324.28900-1.6212017.7162016.19330K562RBM15
DET1ENSG00000140543.996.67060157.97240-0.708502.337301.58950K562RPS19
DET1ENSG00000140543.983.97730128.55610-0.614302.063301.32680K562SF3B4
DET1ENSG00000140543.9273.75360152.411900.844802.840001.51410K562SFPQ
DET1ENSG00000140543.997.36690158.42360-0.702302.710202.00970K562SRSF1
DET1ENSG00000140543.9184.81750123.751800.578602.547401.77650K562U2AF2
DET1ENSG00000140543.9152.36060337.44800-1.147205.848303.77660K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DET1 is not available on ENCORE database.





5 RBPs can affect the splicing of DET1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDET1ENSG00000140543.9chr15-8908784189087925890748398907494689089770890898650.254000.009300.09949includedK562PUS1
SEDET1ENSG00000140543.9chr15-890555818905564389054789890548178906001289060204-0.528000.000790.09006excludedK562LARP4
SEDET1ENSG00000140543.9chr15-890555818905637189054789890548178906001289060204-0.412000.000220.02299excludedK562HNRNPUL1
SEDET1ENSG00000140543.9chr15-8905558189056371890547898905481789060012890602040.346000.002550.04132includedK562HNRNPC
RIDET1ENSG00000140543.9chr15-8907385389074946890738538907470489074843890749460.374000.007330.09169includedHepG2FUBP3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DET1 is not avaliable on ENCORE database.