CREM

General Information

Gene Name       : CREM
Gene ID             : ENSG00000095794.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CREM)


Antibody Validation


Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CREMENSG00000095794.1937.8140.6139.21ENCSR000AEF
HepG2CREMENSG00000095794.1918.0219.3318.67ENCSR985KAT
K562CREMENSG00000095794.1931.9234.5133.22ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CREM is not avaliable on ENCORE database.



Proteins bound to RNA

  • CREM RNA is bound by 7 proteins.  







eCLIP assay for CREM is not avaliable on ENCORE database.





7 proteins are bound to CREM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr103546807435468190+3'-UTR,5'-UTR,CDS,intron-Distal3.687844.51739HepG2BCLAF1
chr103550019135500301+3'-UTR,CDS,intron-Distal3.978373.11168K562ZNF622
chr103541600135416104+5'-UTR3.149263.74019K562DDX3X
chr103543876735438849+intron-Distal4.010256.90182HepG2HNRNPL
chr103549161135491686+intron-Distal4.092613.30440HepG2QKI
chr103543878335438908+intron-Distal4.456354.71638K562HNRNPL
chr103543298635433148+intron-Distal3.962095.63625HepG2HNRNPM
chr103548437135484487+intron-Distal4.547465.14122HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CREM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CREM is not available on ENCORE database.

  • 50 RBPs can affect the levels of CREM.  








The Knockdown/knockout RNA-Seq assay for CREM is not available on ENCORE database.





50 RBPs can affect the gene expression of CREM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CREMENSG00000095794.15263.81710177.839200.568902.735102.13990HepG2BOP1
CREMENSG00000095794.15245.68700347.05320-0.498302.299501.72410HepG2DDX3X
CREMENSG00000095794.15123.67800189.30700-0.614102.123901.43770HepG2DDX55
CREMENSG00000095794.15431.88030316.744500.447202.215101.64100HepG2EIF4A3
CREMENSG00000095794.15162.95750308.35490-0.920104.708503.82530HepG2EIF4B
CREMENSG00000095794.15113.39440181.63370-0.679702.896602.09300HepG2FUBP3
CREMENSG00000095794.15223.87440319.51810-0.513202.366501.72430HepG2FXR1
CREMENSG00000095794.15215.52020296.43340-0.459901.896001.34000HepG2G3BP1
CREMENSG00000095794.15111.48110220.13750-0.981604.736603.28980HepG2GRSF1
CREMENSG00000095794.15212.65750300.08730-0.496902.178201.55330HepG2HNRNPK
CREMENSG00000095794.15200.29340273.98490-0.452002.568501.91770HepG2HNRNPL
CREMENSG00000095794.15115.38010162.83070-0.497001.884301.37420HepG2HNRNPU
CREMENSG00000095794.15494.54720302.671300.708304.389603.33670HepG2LARP4
CREMENSG00000095794.15215.78610329.00850-0.608503.032102.37100HepG2NCBP2
CREMENSG00000095794.15193.83590298.23830-0.621604.026903.10710HepG2NOL12
CREMENSG00000095794.15190.50580302.23660-0.665804.754903.99480HepG2PCBP1
CREMENSG00000095794.15194.73400307.52470-0.659204.669904.00030HepG2PTBP1
CREMENSG00000095794.15239.46690302.19700-0.335701.915201.40240HepG2PUM1
CREMENSG00000095794.15383.19850190.241401.010204.908403.98460HepG2RAVER1
CREMENSG00000095794.15380.87890287.860500.403902.262001.78040HepG2RBM22
CREMENSG00000095794.15251.34080342.25570-0.445402.503901.98500HepG2NELFE
CREMENSG00000095794.15241.88300318.74620-0.398102.085101.53990HepG2RECQL
CREMENSG00000095794.15244.26350174.848600.482201.939801.34240HepG2SF3B1
CREMENSG00000095794.15219.63230320.19500-0.543903.344802.70210HepG2SF3B4
CREMENSG00000095794.15119.73170194.54630-0.700302.265101.56140HepG2SNRNP70
CREMENSG00000095794.15189.47980294.36460-0.635602.684501.86060HepG2UBE2L3
CREMENSG00000095794.15433.06790304.278700.509103.056501.80780K562AARS
CREMENSG00000095794.15737.36520591.965600.316802.562502.01170K562AGGF1
CREMENSG00000095794.15553.76330807.41940-0.544004.428203.71780K562AQR
CREMENSG00000095794.15493.74930370.057900.415902.168701.40290K562BOP1
CREMENSG00000095794.15568.98060417.338200.447102.934301.61190K562CIRBP
CREMENSG00000095794.15588.63710323.225700.864708.656706.96020K562EFTUD2
CREMENSG00000095794.15227.49660308.63310-0.440002.188501.45530K562EIF4A3
CREMENSG00000095794.15203.87110277.93510-0.447102.439401.37650K562EIF4B
CREMENSG00000095794.15422.00160308.494500.451902.631401.32620K562FUS
CREMENSG00000095794.15425.77770320.964400.407602.569201.98170K562FXR1
CREMENSG00000095794.15532.42180375.724300.502803.408502.52990K562GPKOW
CREMENSG00000095794.15515.29370717.75100-0.478103.707102.83590K562GRSF1
CREMENSG00000095794.15600.64250388.867800.627104.628702.99650K562HNRNPK
CREMENSG00000095794.15884.33910580.836800.606405.744804.61360K562HSPD1
CREMENSG00000095794.15936.03620732.305400.354002.716601.81850K562MBNL1
CREMENSG00000095794.151190.94600858.281500.472504.283802.88230K562MSI2
CREMENSG00000095794.15297.57450442.87350-0.573604.839103.79250K562MTPAP
CREMENSG00000095794.15514.72320364.093600.499403.233202.17530K562PCBP2
CREMENSG00000095794.15704.08320486.399800.533504.352103.29200K562PPIG
CREMENSG00000095794.15704.63680314.533901.1636014.5857012.84860K562PRPF8
CREMENSG00000095794.15209.23970298.51770-0.512702.231801.42740K562PSIP1
CREMENSG00000095794.15671.84110397.618200.756608.987107.83460K562PTBP1
CREMENSG00000095794.151189.65240878.555800.437203.246802.36400K562PUF60
CREMENSG00000095794.151119.94220915.604000.290502.398801.50340K562PUM2
CREMENSG00000095794.15777.82250610.875500.348502.058901.57740K562PUS1
CREMENSG00000095794.15435.32500268.493800.697103.176901.63940K562RAVER1
CREMENSG00000095794.15532.10070381.174200.481103.316702.39070K562RBM22
CREMENSG00000095794.15492.76420357.244200.463902.342301.45460K562SF3B1
CREMENSG00000095794.15844.59250389.817801.1154018.4328016.63210K562SRSF1
CREMENSG00000095794.15192.03790287.12410-0.580302.710701.78440K562TIAL1
CREMENSG00000095794.15477.99660272.720900.809506.119504.35390K562U2AF1
CREMENSG00000095794.15597.61890281.682401.0851015.6769013.73950K562U2AF2
CREMENSG00000095794.15472.71680322.367800.552203.600402.42560K562UCHL5
CREMENSG00000095794.15372.10880464.25460-0.319202.176501.41890K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CREM is not available on ENCORE database.





12 RBPs can affect the splicing of CREM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECREMENSG00000095794.15chr10+3549037835490414354848363548502735495822354959790.526000.005250.07861includedK562SRSF1
SECREMENSG00000095794.15chr10+354372953543741935416029354161213546781635467914-0.272000.002840.04845excludedK562SRSF1
SECREMENSG00000095794.15chr10+3542670935426807354159163541612135437295354374190.067000.000020.00721includedK562FTO
SECREMENSG00000095794.15chr10+3550014435500317354957973549597935500583355018830.437000.000000.00002includedK562AQR
SECREMENSG00000095794.15chr10+3544120735441308354372953543741935467816354679140.115000.000100.00167includedK562AQR
SECREMENSG00000095794.15chr10+3544120735441308354372953543741935467816354679140.089000.000550.01033includedK562PUS1
SECREMENSG00000095794.15chr10+354678163546791435437295354374193546806135468204-0.066000.002280.03346excludedK562PUS1
SECREMENSG00000095794.15chr10+3549037835490414354680613546820435495822354959790.412000.003220.06324includedHepG2SRSF1
SECREMENSG00000095794.15chr10+354372953543741935416029354161213546781635467914-0.282000.001750.07122excludedHepG2SF3B4
SECREMENSG00000095794.15chr10+3543729535437419354160293541612135467816354679140.159000.000440.07110includedK562UPF1
SECREMENSG00000095794.15chr10+355001813550031735495797354959793550058335500788-0.476000.000000.00000excludedK562U2AF2
SECREMENSG00000095794.15chr10+354680613546820435437299354374193549582235495979-0.555000.000020.00167excludedK562HNRNPU
SECREMENSG00000095794.15chr10+354372953543741935416029354161213546781635467914-0.319000.000180.05932excludedHepG2DROSHA
A3SSCREMENSG00000095794.15chr10+355001813550188335500583355018833549579735495979-0.483000.000000.00000shorterK562U2AF2
A3SSCREMENSG00000095794.15chr10+3550014435500326355001813550032635495797354959790.135000.000000.00000longerK562AQR
A3SSCREMENSG00000095794.15chr10+355001813550188335500583355018833549579735495979-0.427000.000000.00021shorterK562U2AF1
MXECREMENSG00000095794.15chr10+3547712735477316354903783549041435468061354682043549582235495979-0.505000.000300.009072includedHepG2SRSF1
MXECREMENSG00000095794.15chr10+3543729535437419354680613546820435415990354161213547712735477316-0.212000.002450.019772includedK562AQR
MXECREMENSG00000095794.15chr10+3547712735477316354903783549041435468061354682043549582235495979-0.523000.000880.057082includedK562RBM22
MXECREMENSG00000095794.15chr10+3547712735477316354903783549041435468061354682043549582235495979-0.486000.000900.052302includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CREM is not avaliable on ENCORE database.