CASP4

General Information

Gene Name       : CASP4
Gene ID             : ENSG00000196954.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CASP4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CASP4ENSG00000196954.1382.2976.6779.48ENCSR000AEF
HepG2CASP4ENSG00000196954.1324.9434.6429.79ENCSR985KAT
K562CASP4ENSG00000196954.130.060.250.15ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CASP4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CASP4 RNA is bound by 1 proteins.  







eCLIP assay for CASP4 is not avaliable on ENCORE database.





1 proteins are bound to CASP4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11104814958104815023-intron-Distal4.058934.21977HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CASP4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CASP4 is not available on ENCORE database.

  • 59 RBPs can affect the levels of CASP4.  








The Knockdown/knockout RNA-Seq assay for CASP4 is not available on ENCORE database.





59 RBPs can affect the gene expression of CASP4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CASP4ENSG00000196954.8385.21590544.61380-0.499603.270402.19150HepG2ADAR
CASP4ENSG00000196954.8898.79080597.782800.588308.360507.11710HepG2AKAP8L
CASP4ENSG00000196954.8929.68650705.604200.397802.597301.83560HepG2ASCC1
CASP4ENSG00000196954.81357.37600966.072800.490504.984803.15580HepG2ATP5C1
CASP4ENSG00000196954.8597.026701063.29440-0.832707.552706.62420HepG2BOP1
CASP4ENSG00000196954.81422.83170830.091700.7773013.3937011.91610HepG2CALR
CASP4ENSG00000196954.81402.41000980.446300.516303.513002.40150HepG2CCAR1
CASP4ENSG00000196954.81200.94510670.369300.8410010.382508.96980HepG2CIRBP
CASP4ENSG00000196954.8844.39120594.849600.505306.994706.02470HepG2CKAP4
CASP4ENSG00000196954.81085.20270554.254600.969207.656006.39420HepG2CNOT7
CASP4ENSG00000196954.81269.38580976.193700.378803.017402.30350HepG2CPSF6
CASP4ENSG00000196954.8224.73310324.40850-0.529602.714501.64670HepG2CSTF2
CASP4ENSG00000196954.81144.67080840.716100.445107.038805.93590HepG2DAZAP1
CASP4ENSG00000196954.8688.63920550.293100.323403.019202.15060HepG2DDX19B
CASP4ENSG00000196954.8743.09480537.346400.467602.380501.74540HepG2DDX21
CASP4ENSG00000196954.8687.16860526.173100.385002.755501.84540HepG2DDX24
CASP4ENSG00000196954.81436.41060816.909400.814109.699808.59010HepG2DDX3X
CASP4ENSG00000196954.81251.57610856.779000.546705.646303.84360HepG2DDX47
CASP4ENSG00000196954.8814.31950569.267800.516406.030405.10360HepG2DKC1
CASP4ENSG00000196954.8691.30980543.568400.346802.265301.66240HepG2DNAJC2
CASP4ENSG00000196954.8975.69480674.603300.532304.160603.44200HepG2EIF2S1
CASP4ENSG00000196954.81437.02980725.840900.985309.908008.64560HepG2EIF4B
CASP4ENSG00000196954.8988.96000829.447800.253702.122301.37300HepG2EIF4G1
CASP4ENSG00000196954.81297.09230794.552500.707008.728507.31350HepG2EIF4G2
CASP4ENSG00000196954.81491.674801193.400000.321803.864203.17400HepG2ETF1
CASP4ENSG00000196954.8736.51490581.405100.341102.334201.56790HepG2EWSR1
CASP4ENSG00000196954.8660.05000512.249700.365602.451701.37060HepG2FASTKD2
CASP4ENSG00000196954.81662.80300977.801400.765903.363602.23840HepG2FTO
CASP4ENSG00000196954.8606.40210445.838300.443702.836901.92690HepG2GEMIN5
CASP4ENSG00000196954.8766.80920553.645000.469803.473902.75990HepG2HNRNPA1
CASP4ENSG00000196954.8817.53170615.834300.408602.880402.17420HepG2HNRNPC
CASP4ENSG00000196954.8786.84740624.893800.332402.035101.39490HepG2ILF2
CASP4ENSG00000196954.81393.61260972.507300.518903.350701.76820HepG2NKRF
CASP4ENSG00000196954.8894.61870750.128600.254002.049301.51450HepG2PCBP1
CASP4ENSG00000196954.8732.62260923.87330-0.334603.406802.55790HepG2PRPF4
CASP4ENSG00000196954.8658.03600398.336700.724105.800804.67930HepG2PRPF8
CASP4ENSG00000196954.81051.34620844.793800.315503.894203.21630HepG2PUM1
CASP4ENSG00000196954.81008.36890844.169800.256301.863201.30730HepG2PUM2
CASP4ENSG00000196954.8751.05800606.067400.309302.776902.15990HepG2PUS1
CASP4ENSG00000196954.8683.13520826.65530-0.275101.903401.37020HepG2QKI
CASP4ENSG00000196954.81408.81220959.387000.554203.312602.38370HepG2RBM15
CASP4ENSG00000196954.8603.41600750.24280-0.314202.041201.45620HepG2RBM25
CASP4ENSG00000196954.8664.83110849.46170-0.353603.171302.59990HepG2NELFE
CASP4ENSG00000196954.8635.73670791.15820-0.315502.610002.00920HepG2RECQL
CASP4ENSG00000196954.8538.56280394.035300.450702.272801.55320HepG2RRP9
CASP4ENSG00000196954.8828.50200544.797500.604709.044807.98590HepG2SAFB2
CASP4ENSG00000196954.8687.27420489.024200.490903.655702.56970HepG2SERBP1
CASP4ENSG00000196954.81231.14830950.501000.373102.034201.45520HepG2SF3A3
CASP4ENSG00000196954.8845.983901163.16780-0.459402.251001.54940HepG2SNRNP70
CASP4ENSG00000196954.82731.101001126.581901.2774066.1467064.53730HepG2SRFBP1
CASP4ENSG00000196954.81935.929701124.707400.783408.091706.30400HepG2SRSF3
CASP4ENSG00000196954.81444.348701035.237500.480403.175101.74910HepG2SUGP2
CASP4ENSG00000196954.81440.171701029.156700.484704.777903.85980HepG2TARDBP
CASP4ENSG00000196954.81174.73300924.690900.345202.292901.71630HepG2U2AF1
CASP4ENSG00000196954.81159.64530911.765700.346804.371403.55810HepG2ZC3H8
CASP4ENSG00000196954.81079.61300927.082300.219602.149101.64940HepG2ZNF622
CASP4ENSG00000196954.87.597700.0000099999.999902.159301.51060K562EIF2S2
CASP4ENSG00000196954.811.874500.0000099999.999902.637601.89870K562GRSF1
CASP4ENSG00000196954.816.560700.974904.086303.204502.19140K562KRR1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CASP4 is not available on ENCORE database.





2 RBPs can affect the splicing of CASP4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECASP4ENSG00000196954.8chr11-1048273231048274221048254731048257281048392451048393020.098000.000000.00000includedHepG2SRSF9
A3SSCASP4ENSG00000196954.8chr11-1048226221048227901048226221048227321048254731048257280.087000.000070.00390longerHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CASP4 is not avaliable on ENCORE database.