ADAL

General Information

Gene Name       : ADAL
Gene ID             : ENSG00000168803.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ADAL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ADALENSG00000168803.1512.5010.6511.57ENCSR000AEF
HepG2ADALENSG00000168803.156.2411.548.89ENCSR985KAT
K562ADALENSG00000168803.1518.3320.2919.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ADAL is not avaliable on ENCORE database.



Proteins bound to RNA
  • ADAL RNA is bound by 5 proteins.  







eCLIP assay for ADAL is not avaliable on ENCORE database.





5 proteins are bound to ADAL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr154364483343644882+3'-UTR4.504144.22051K562UPF1
chr154364416343644290+3'-UTR3.745823.46958K562YBX3
chr154364515643645176+3'-UTR5.308648.00788K562UPF1
chr154364517643645204+3'-UTR3.960418.62096K562UPF1
chr154364579843645859+3'-UTR3.964683.76295K562LIN28B
chr154362881443629049+CDS,intron-Distal,intron-Proximal3.638506.70109K562PRPF8
chr154363503743635105+intron-Distal,intron-Proximal3.984063.55640HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ADAL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ADAL is not available on ENCORE database.

  • 45 RBPs can affect the levels of ADAL.  








The Knockdown/knockout RNA-Seq assay for ADAL is not available on ENCORE database.





45 RBPs can affect the gene expression of ADAL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ADALENSG00000168803.10180.94820323.25120-0.837105.429504.49620HepG2CPSF6
ADALENSG00000168803.10232.95440367.07680-0.656002.697701.73410HepG2DDX59
ADALENSG00000168803.10206.05500299.24570-0.538302.358801.50570HepG2EEF2
ADALENSG00000168803.10225.02530312.44530-0.473502.036301.51810HepG2EIF2S1
ADALENSG00000168803.10343.40430568.57520-0.727404.836004.08090HepG2ETF1
ADALENSG00000168803.10258.11040366.41970-0.505502.348301.75490HepG2GPKOW
ADALENSG00000168803.10307.51310400.03130-0.379502.113901.52360HepG2PUM2
ADALENSG00000168803.10361.01730248.878600.536502.761402.14590HepG2PUS1
ADALENSG00000168803.10241.29890475.20940-0.977708.197007.41510HepG2RBM22
ADALENSG00000168803.10233.02360360.93040-0.631203.241002.51040HepG2SF3A3
ADALENSG00000168803.10227.03870354.60520-0.643304.540903.81170HepG2SF3B4
ADALENSG00000168803.10302.69360536.70630-0.826306.320105.64710HepG2SRFBP1
ADALENSG00000168803.10566.07630372.433100.603903.424302.29880HepG2SRSF3
ADALENSG00000168803.10211.55010301.14080-0.509403.125602.54610HepG2SRSF9
ADALENSG00000168803.10164.24470252.68890-0.621502.174601.56470HepG2SUPV3L1
ADALENSG00000168803.10419.76290332.731000.335101.902001.42170HepG2TAF15
ADALENSG00000168803.10204.19210298.87220-0.549603.678503.04780HepG2TRIM56
ADALENSG00000168803.10206.08660418.56270-1.022202.702301.72610HepG2U2AF2
ADALENSG00000168803.10449.00020309.034700.538804.145703.43560HepG2UTP3
ADALENSG00000168803.10417.28240291.823700.515802.350701.37430HepG2XRCC6
ADALENSG00000168803.10218.44820349.14050-0.676505.637404.73040HepG2ZC3H8
ADALENSG00000168803.101057.441401491.42760-0.496104.837203.20010K562ABCF1
ADALENSG00000168803.10698.568301074.91560-0.621807.601306.72660K562AGGF1
ADALENSG00000168803.10939.123601181.05110-0.330702.684901.72140K562AKAP8
ADALENSG00000168803.10833.492501118.46920-0.424303.865203.09140K562AKAP8L
ADALENSG00000168803.10711.917901222.00580-0.7795010.155309.13920K562AQR
ADALENSG00000168803.10949.528501173.48830-0.305502.563701.68650K562ATP5C1
ADALENSG00000168803.10698.74280951.58370-0.445604.144303.18260K562CPSF6
ADALENSG00000168803.10382.84030607.22490-0.665505.266203.98490K562EFTUD2
ADALENSG00000168803.10712.37750943.41220-0.405204.170903.31470K562EIF2S2
ADALENSG00000168803.10847.14990632.255500.422002.281601.64750K562G3BP2
ADALENSG00000168803.10590.88240908.52020-0.620606.473705.26330K562GPKOW
ADALENSG00000168803.101054.66650694.973200.601706.930606.02610K562HNRNPC
ADALENSG00000168803.10868.788501176.71000-0.437704.223502.88970K562HNRNPL
ADALENSG00000168803.10543.19170769.48780-0.502404.323602.75590K562IGF2BP3
ADALENSG00000168803.10929.387301187.07760-0.353103.030702.16370K562KIF1C
ADALENSG00000168803.10547.59250795.17900-0.538205.136103.98340K562MAGOH
ADALENSG00000168803.10864.955701136.24240-0.393603.407002.17570K562MAK16
ADALENSG00000168803.101048.629601329.81250-0.342703.096502.12510K562MBNL1
ADALENSG00000168803.10591.92100881.95940-0.575302.198401.33670K562PABPN1
ADALENSG00000168803.10537.37070707.54420-0.396902.699001.73260K562PCBP2
ADALENSG00000168803.10427.84020590.89960-0.465802.826102.06910K562PRPF8
ADALENSG00000168803.10795.700701080.79290-0.441803.614102.94980K562RBM15
ADALENSG00000168803.10528.97520740.88140-0.486003.911102.89910K562RBM22
ADALENSG00000168803.10889.13590664.890200.419203.140501.59570K562SDAD1
ADALENSG00000168803.10451.64780657.73990-0.542305.132803.94860K562SF3B4
ADALENSG00000168803.10299.34200757.34010-1.3391023.4911021.42650K562SRSF1
ADALENSG00000168803.10422.95100766.51970-0.857809.762708.30390K562TARDBP
ADALENSG00000168803.10570.22150739.38380-0.374802.712901.90420K562TIA1
ADALENSG00000168803.10465.25070636.50310-0.452203.089102.07890K562TRIM56
ADALENSG00000168803.10924.057901217.78690-0.398202.814301.60230K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ADAL is not available on ENCORE database.





8 RBPs can affect the splicing of ADAL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEADALENSG00000168803.10chr15+4363109343631294436288234362888443632462436325500.253000.000000.00001includedK562SRSF1
SEADALENSG00000168803.10chr15+436392134363929443638051436381784364110443641610-0.254000.003090.03595excludedHepG2U2AF2
SEADALENSG00000168803.10chr15+436240974362419843622871436230574362550843625632-0.594000.000120.00239excludedHepG2U2AF2
SEADALENSG00000168803.10chr15+436392134363929443638051436381784364110443641610-0.103000.002590.03702excludedK562PUS1
SEADALENSG00000168803.10chr15+436392134363929443638051436381784364110443641610-0.314000.000000.00004excludedK562U2AF1
SEADALENSG00000168803.10chr15+436392134363929443638051436381784364110443641610-0.291000.000000.00004excludedK562U2AF2
SEADALENSG00000168803.10chr15+436392134363929443638051436381784364110443641610-0.119000.002570.05689excludedK562AGGF1
SEADALENSG00000168803.10chr15+436271424362736843624097436241984362789343628024-0.146000.001630.04058excludedK562AGGF1
SEADALENSG00000168803.10chr15+436315744363162843628823436288844363246243632550-0.054000.001120.02121excludedK562HNRNPC
A5SSADALENSG00000168803.10chr15+4363246243632575436324624363255043635191436352730.129000.000500.07039longerK562TARDBP
MXEADALENSG00000168803.10chr15+43627142436273684362789343628024436240974362419843628823436288840.060000.015330.089071includedK562AQR
MXEADALENSG00000168803.10chr15+43624076436241984362550843625632436229244362305743627142436273680.627000.000130.001531includedK562AQR
MXEADALENSG00000168803.10chr15+43627871436280244362882343628884436271424362736843632462436325500.076000.001860.015631includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ADAL is not avaliable on ENCORE database.