HMGCS1

General Information

Gene Name : HMGCS1
Gene ID : ENSG00000112972.14
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HMGCS1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HMGCS1	ENSG00000112972.14	157.94	125.92	141.93	ENCSR000AEF
HepG2	HMGCS1	ENSG00000112972.14	97.51	161.84	129.68	ENCSR985KAT
K562	HMGCS1	ENSG00000112972.14	100.32	110.83	105.57	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HMGCS1 is not avaliable on ENCORE database.

Proteins bound to RNA

HMGCS1 RNA is bound by 48 proteins.

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eCLIP assay for HMGCS1 is not avaliable on ENCORE database.

48 proteins are bound to HMGCS1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr5	43291116	43291199	-	3'-UTR,intron-Distal	5.37412	400.00000	HepG2	PCBP2
chr5	43291076	43291186	-	3'-UTR,intron-Distal	4.45689	87.15591	K562	DDX6
chr5	43291140	43291196	-	3'-UTR,intron-Distal	4.86143	78.12604	HepG2	GTF2F1
chr5	43291079	43291188	-	3'-UTR,intron-Distal	3.70387	74.61273	K562	LARP4
chr5	43298657	43298759	-	CDS,intron-Distal,intron-Proximal	3.33702	62.46675	HepG2	BCLAF1
chr5	43313337	43313442	-	intron-Distal,intron-Proximal	4.72550	61.90125	HepG2	EFTUD2
chr5	43291089	43291195	-	3'-UTR,intron-Distal	3.51802	57.48030	K562	FASTKD2
chr5	43291118	43291186	-	3'-UTR,intron-Distal	4.31851	48.63272	K562	UPF1
chr5	43297183	43297216	-	CDS,intron-Distal	3.71427	48.30196	HepG2	BCLAF1
chr5	43291115	43291187	-	3'-UTR,intron-Distal	3.46313	45.14897	K562	CSTF2T
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 214 entries

eCLIP assay for HMGCS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HMGCS1 is not available on ENCORE database.
190 RBPs can affect the levels of HMGCS1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HMGCS1 is not available on ENCORE database.

190 RBPs can affect the gene expression of HMGCS1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HMGCS1	ENSG00000112972.10	1726.81440	8920.53330	-2.36900	99999.99999	99999.99999	HepG2	HNRNPL
HMGCS1	ENSG00000112972.10	7514.58710	31318.19460	-2.05920	267.69630	264.79060	HepG2	NELFE
HMGCS1	ENSG00000112972.10	9180.09680	30581.10450	-1.73610	234.07560	231.60810	HepG2	SRSF1
HMGCS1	ENSG00000112972.10	8246.05740	29168.91860	-1.82270	219.98030	216.47150	HepG2	RECQL
HMGCS1	ENSG00000112972.10	40035.47680	8414.85840	2.25020	178.57210	176.25850	HepG2	SSB
HMGCS1	ENSG00000112972.10	1801.49310	9601.93920	-2.41410	155.78030	151.97740	K562	HNRNPC
HMGCS1	ENSG00000112972.10	37054.17020	7796.71340	2.24860	131.99010	127.59200	K562	AKAP8L
HMGCS1	ENSG00000112972.10	13212.45290	4026.97810	1.71400	128.63620	125.34800	HepG2	PRPF4
HMGCS1	ENSG00000112972.10	4215.74940	10408.64370	-1.30390	126.86930	123.96790	HepG2	SUCLG1
HMGCS1	ENSG00000112972.10	4321.82430	9839.93220	-1.18700	121.44890	118.86360	HepG2	PUM1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 269 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HMGCS1 is not available on ENCORE database.

48 RBPs can affect the splicing of HMGCS1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	HMGCS1	ENSG00000112972.10	chr5	-	43298110	43298236	43297103	43297268	43298619	43299077	-0.24500	0.00000	excluded	K562	SF3B4
SE	HMGCS1	ENSG00000112972.10	chr5	-	43307867	43307926	43298619	43299077	43313457	43313595	-0.15200	0.00001	excluded	K562	SF3B4
SE	HMGCS1	ENSG00000112972.10	chr5	-	43298110	43298236	43297103	43297268	43298619	43299077	-0.10300	0.00000	excluded	K562	AKAP8L
SE	HMGCS1	ENSG00000112972.10	chr5	-	43307867	43307926	43298619	43299077	43313457	43313595	0.13000	0.00018	included	HepG2	TBRG4
SE	HMGCS1	ENSG00000112972.10	chr5	-	43298110	43298236	43297103	43297268	43298619	43299077	0.09100	0.00000	included	K562	FXR1
SE	HMGCS1	ENSG00000112972.10	chr5	-	43298110	43298236	43297103	43297268	43298619	43299077	-0.23500	0.00000	excluded	K562	PUS1
SE	HMGCS1	ENSG00000112972.10	chr5	-	43307867	43307926	43298619	43299077	43313457	43313595	-0.17700	0.00000	excluded	K562	PUS1
SE	HMGCS1	ENSG00000112972.10	chr5	-	43307867	43307946	43298547	43299077	43313123	43313326	-0.09700	0.00000	excluded	HepG2	MATR3
SE	HMGCS1	ENSG00000112972.10	chr5	-	43298110	43298236	43297103	43297268	43298619	43299077	-0.14500	0.00000	excluded	K562	U2AF1
SE	HMGCS1	ENSG00000112972.10	chr5	-	43307867	43307926	43298619	43299077	43313457	43313595	-0.19000	0.00013	excluded	K562	HNRNPL

Showing 1 to 10 of 67 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HMGCS1

General Information

Functions

Localization

Domains (AlphaFold: HMGCS1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HMGCS1 is not avaliable on ENCORE database.

48 proteins are bound to HMGCS1 RNA:

eCLIP assay for HMGCS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HMGCS1 is not available on ENCORE database.

190 RBPs can affect the gene expression of HMGCS1 :

The Knockdown/knockout RNA-Seq assay for HMGCS1 is not available on ENCORE database.

48 RBPs can affect the splicing of HMGCS1 :

The Knockdown/knockout RNA-Seq assay for HMGCS1 is not avaliable on ENCORE database.