TTF2

General Information

Gene Name : TTF2
Gene ID : ENSG00000116830.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TTF2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TTF2	ENSG00000116830.11	59.73	43.45	51.59	ENCSR000AEF
HepG2	TTF2	ENSG00000116830.11	19.72	27.05	23.38	ENCSR985KAT
K562	TTF2	ENSG00000116830.11	26.03	28.31	27.17	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	TTF2-BGRSLV02-RS293		TTF2	Ribo-STAMP-293T	Released			shRNA	KD% = ,

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
TTF2	Ribo-STAMP-293T	shRNA			TTF2-BGRSLV02-39,TTF2-BGRSLV02-40	NT-BGRSLV02-1,NT-BGRSLV02-2	,	Released	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TTF2 is not avaliable on ENCORE database.

Proteins bound to RNA

TTF2 RNA is bound by 22 proteins.

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eCLIP assay for TTF2 is not avaliable on ENCORE database.

22 proteins are bound to TTF2 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	117645309	117645384	+	3'-UTR	9.91335	198.28827	K562	QKI
chr1	117645318	117645399	+	3'-UTR	8.88515	118.30197	HepG2	QKI
chr1	117645399	117645430	+	3'-UTR	9.28632	116.92538	K562	QKI
chr1	117645430	117645483	+	3'-UTR	7.82932	109.92435	K562	QKI
chr1	117645428	117645479	+	3'-UTR	8.68034	80.34968	HepG2	QKI
chr1	117645399	117645428	+	3'-UTR	8.52871	69.05207	HepG2	QKI
chr1	117628872	117628973	+	intron-Distal,intron-Proximal	5.32684	20.39159	K562	TARDBP
chr1	117618303	117618463	+	CDS	3.61486	16.17904	K562	UCHL5
chr1	117617714	117617826	+	CDS	3.91147	15.86208	K562	ZNF622
chr1	117617715	117617837	+	CDS	4.10165	13.63763	K562	UCHL5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 73 entries

eCLIP assay for TTF2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TTF2 is not available on ENCORE database.
144 RBPs can affect the levels of TTF2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for TTF2 is not available on ENCORE database.

144 RBPs can affect the gene expression of TTF2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TTF2	ENSG00000116830.7	357.32500	941.28250	-1.39740	43.79000	42.29080	HepG2	ZNF622
TTF2	ENSG00000116830.7	204.35740	844.91710	-2.04770	35.82280	33.92560	HepG2	SUPV3L1
TTF2	ENSG00000116830.7	1005.26660	2234.55980	-1.15240	30.51170	28.17070	K562	SRSF1
TTF2	ENSG00000116830.7	210.07630	750.07860	-1.83610	30.16220	27.74730	HepG2	BCLAF1
TTF2	ENSG00000116830.7	313.65270	886.74640	-1.49940	28.03700	26.36230	HepG2	RPLP0
TTF2	ENSG00000116830.7	378.48720	855.86070	-1.17710	27.59950	25.86010	HepG2	UPF1
TTF2	ENSG00000116830.7	720.99580	1454.92110	-1.01290	26.89210	25.34520	HepG2	ETF1
TTF2	ENSG00000116830.7	1632.98760	3428.58540	-1.07010	24.18210	22.63860	K562	AQR
TTF2	ENSG00000116830.7	1537.72060	2595.09320	-0.75500	22.97960	21.45690	K562	AGGF1
TTF2	ENSG00000116830.7	510.33100	1132.63190	-1.15020	22.87280	21.39260	HepG2	CELF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 188 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TTF2 is not available on ENCORE database.

9 RBPs can affect the splicing of TTF2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TTF2	ENSG00000116830.7	chr1	+	117629038	117629144			117624452	117624569	117631422	117631604	-0.32600	0.00000	0.00000	excluded	K562	RBM15
SE	TTF2	ENSG00000116830.7	chr1	+	117629038	117629144			117624452	117624569	117631422	117631604	-0.24400	0.00005	0.00128	excluded	K562	PUS1
MXE	TTF2	ENSG00000116830.7	chr1	+	117639972	117640055	117640827	117640860	117638770	117638921	117641454	117641529	-0.16000	0.00013	0.00366	2included	K562	SRSF1
SE	TTF2	ENSG00000116830.7	chr1	+	117630526	117630592			117629038	117629144	117631422	117631604	0.08900	0.00018	0.04063	included	K562	NPM1
SE	TTF2	ENSG00000116830.7	chr1	+	117640827	117640860			117639972	117640055	117641454	117641529	0.26400	0.00036	0.00915	included	K562	SRSF1
SE	TTF2	ENSG00000116830.7	chr1	+	117622189	117622271			117620537	117620665	117624449	117624569	-0.07100	0.00047	0.00639	excluded	K562	AQR
SE	TTF2	ENSG00000116830.7	chr1	+	117622189	117622271			117620516	117620665	117624449	117624569	-0.15700	0.00064	0.01451	excluded	K562	SF3B4
A3SS	TTF2	ENSG00000116830.7	chr1	+	117644815	117644984			117644855	117644984	117644001	117644184	-0.41200	0.00223	0.01418	shorter	K562	AQR
SE	TTF2	ENSG00000116830.7	chr1	+	117634438	117634572			117633949	117634032	117635352	117635523	-0.10000	0.00249	0.04356	excluded	K562	SRSF1
SE	TTF2	ENSG00000116830.7	chr1	+	117630529	117630592			117629038	117629144	117631422	117631604	0.10000	0.00352	0.07029	included	K562	RBM15

Showing 1 to 10 of 14 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TTF2

General Information

Functions

Localization

Domains (AlphaFold: TTF2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TTF2 is not avaliable on ENCORE database.

22 proteins are bound to TTF2 RNA:

eCLIP assay for TTF2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TTF2 is not available on ENCORE database.

144 RBPs can affect the gene expression of TTF2 :

The Knockdown/knockout RNA-Seq assay for TTF2 is not available on ENCORE database.

9 RBPs can affect the splicing of TTF2 :

The Knockdown/knockout RNA-Seq assay for TTF2 is not avaliable on ENCORE database.