CACNA2D4

General Information

Gene Name       : CACNA2D4
Gene ID             : ENSG00000151062.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CACNA2D4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CACNA2D4ENSG00000151062.140.280.340.31ENCSR000AEF
HepG2CACNA2D4ENSG00000151062.1425.3514.8520.10ENCSR985KAT
K562CACNA2D4ENSG00000151062.140.320.260.29ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CACNA2D4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CACNA2D4 RNA is bound by 18 proteins.  







eCLIP assay for CACNA2D4 is not avaliable on ENCORE database.





18 proteins are bound to CACNA2D4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1219101661910212-3'-UTR,CDS,intron-Distal,intron-Proximal4.943474.97857HepG2AQR
chr1219091341909222-3'-UTR,CDS,intron-Distal,intron-Proximal3.229193.50686HepG2PPIG
chr1219048331904942-3'-UTR,CDS,intron-Distal,intron-Proximal3.294823.50686HepG2PPIG
chr1219102141910257-3'-UTR,CDS,intron-Distal,intron-Proximal3.665535.26543HepG2RBFOX2
chr1219091511909235-3'-UTR,CDS,intron-Distal,intron-Proximal3.370713.98694HepG2DROSHA
chr1219044121904468-3'-UTR,CDS,intron-Distal,intron-Proximal3.422563.96535HepG2AQR
chr1219092171909268-3'-UTR,CDS,intron-Distal,intron-Proximal4.5510110.39908HepG2SF3B4
chr1219194431919501-3'-UTR,CDS,intron-Distal,intron-Proximal3.192753.17635HepG2PPIG
chr1219087761908854-3'-UTR,CDS,intron-Distal,intron-Proximal4.405898.78144HepG2PRPF8
chr1219020351902234-3'-UTR,intron-Distal,intron-Proximal3.445318.57930HepG2BCLAF1
chr1219102061910265-3'-UTR,CDS,intron-Distal,intron-Proximal4.182219.56105HepG2PPIG
chr1219208621920919-5'-UTR,CDS,intron-Distal,intron-Proximal4.738396.66103HepG2NCBP2
chr1219207621920835-CDS,intron-Distal,intron-Proximal4.193513.25089HepG2AQR
chr1219404171940422-intron-Distal4.278053.47293K562U2AF2
chr1219482531948280-intron-Distal4.336884.19050K562GPKOW
chr1219091561909166-intron-Distal,intron-Proximal4.8976412.48497HepG2PRPF8
chr1219404241940439-intron-Distal6.074458.44266K562U2AF1
chr1219110261911176-intron-Distal4.053985.81300HepG2HNRNPL
chr1219089911909043-intron-Distal5.427655.68502HepG2PRPF8
chr1219093371909436-intron-Distal,intron-Proximal5.6499080.16914HepG2RBFOX2
chr1219404171940430-intron-Distal5.572498.86301K562TRA2A
chr1219482721948279-intron-Distal7.6971729.94884K562NSUN2
chr1219404301940439-intron-Distal5.572498.86301K562TRA2A
chr1219094741909543-intron-Distal,intron-Proximal3.761509.86479HepG2PPIG
chr1219091311909166-intron-Distal,intron-Proximal4.725575.68078HepG2AQR
chr1219089871909044-intron-Distal5.083525.32906HepG2AQR
chr1219092611909337-intron-Distal,intron-Proximal6.29108400.00000HepG2RBFOX2
chr1219094371909548-intron-Distal,intron-Proximal7.57915192.35296HepG2RBFOX2
chr1219092351909350-intron-Distal,intron-Proximal3.215507.17969HepG2DROSHA
chr1219404171940424-intron-Distal6.074458.44266K562U2AF1
chr1219092261909338-intron-Distal,intron-Proximal3.586466.49835HepG2PRPF4
chr1219482541948280-intron-Distal3.182226.29454K562WRN
chr1219090501909098-intron-Distal,intron-Proximal4.653704.45472HepG2RBM22
chr1219404241940439-intron-Distal4.278053.47293K562U2AF2
chr1219482541948272-intron-Distal7.6971729.94884K562NSUN2
chr1219092431909318-intron-Distal,intron-Proximal6.0634411.46503HepG2PRPF8
chr1219111941911246-intron-Distal3.935776.39350HepG2HNRNPL
chr1219091201909156-intron-Distal,intron-Proximal4.8560310.85246HepG2PRPF8
chr1219094771909535-intron-Distal,intron-Proximal3.847257.62597HepG2PRPF8
chr1219198351919922-intron-Distal,intron-Proximal5.085396.37635HepG2HNRNPL
chr1219092181909261-intron-Distal,intron-Proximal6.0277433.14739HepG2RBFOX2
chr1219060931906150-intron-Distal4.032483.38470HepG2NKRF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CACNA2D4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CACNA2D4 is not available on ENCORE database.

  • 132 RBPs can affect the levels of CACNA2D4.  








The Knockdown/knockout RNA-Seq assay for CACNA2D4 is not available on ENCORE database.





132 RBPs can affect the gene expression of CACNA2D4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CACNA2D4ENSG00000151062.10777.86010559.996600.474003.293002.13060HepG2AATF
CACNA2D4ENSG00000151062.10207.77450818.66770-1.9783012.9068011.12670HepG2ABCF1
CACNA2D4ENSG00000151062.101420.79120696.251601.028908.909307.94500HepG2ACO1
CACNA2D4ENSG00000151062.10358.30120685.71180-0.9364010.477808.71440HepG2ADAR
CACNA2D4ENSG00000151062.101218.674901610.39210-0.402102.612302.09470HepG2AKAP1
CACNA2D4ENSG00000151062.10432.16210699.50740-0.694809.569708.24880HepG2AKAP8L
CACNA2D4ENSG00000151062.102191.413401332.419600.717708.930507.57310HepG2ASCC1
CACNA2D4ENSG00000151062.101895.135801323.946900.5174010.235309.05330HepG2AUH
CACNA2D4ENSG00000151062.101051.10950700.934900.584503.828302.72540HepG2BCCIP
CACNA2D4ENSG00000151062.10981.48810608.994400.688405.461404.23840HepG2BCLAF1
CACNA2D4ENSG00000151062.101109.30150543.986801.0279016.4483015.16700HepG2BOP1
CACNA2D4ENSG00000151062.10842.93190613.096200.459202.464701.30400HepG2BUD13
CACNA2D4ENSG00000151062.10921.86600687.940500.422203.957303.05890HepG2CALR
CACNA2D4ENSG00000151062.10960.105001265.90480-0.398902.968002.16780HepG2CIRBP
CACNA2D4ENSG00000151062.10703.20750499.429600.493603.598202.82450HepG2CPSF6
CACNA2D4ENSG00000151062.101348.80270673.852701.0011016.9809014.54720HepG2CPSF7
CACNA2D4ENSG00000151062.10956.38080703.185700.443604.872303.52320HepG2YBX3
CACNA2D4ENSG00000151062.10213.25930432.87220-1.0213010.028508.19370HepG2CSTF2
CACNA2D4ENSG00000151062.10806.33250573.677500.491002.864501.47530HepG2CSTF2T
CACNA2D4ENSG00000151062.102246.184501092.306501.0400035.5456033.77470HepG2CELF1
CACNA2D4ENSG00000151062.101675.620201174.401700.5127011.6740010.31990HepG2DAZAP1
CACNA2D4ENSG00000151062.10467.90860643.92450-0.460705.178704.08470HepG2DDX19B
CACNA2D4ENSG00000151062.101092.29280704.172400.633305.012403.48890HepG2DDX1
CACNA2D4ENSG00000151062.10440.68370617.12700-0.485803.432002.68330HepG2DDX21
CACNA2D4ENSG00000151062.10364.49260604.50240-0.729905.474304.18360HepG2DDX24
CACNA2D4ENSG00000151062.10381.46450644.77550-0.757205.533103.77910HepG2DDX27
CACNA2D4ENSG00000151062.102071.078501542.537900.425003.447402.75860HepG2DDX3X
CACNA2D4ENSG00000151062.102077.253601114.146900.8986016.1510013.51220HepG2DDX47
CACNA2D4ENSG00000151062.10832.98800570.224000.546705.232103.43640HepG2DDX52
CACNA2D4ENSG00000151062.101921.65070689.197401.4793025.1592023.20040HepG2DDX55
CACNA2D4ENSG00000151062.10947.23750567.132400.739904.021902.85760HepG2DDX59
CACNA2D4ENSG00000151062.10377.66830677.43900-0.843008.503006.83890HepG2DDX5
CACNA2D4ENSG00000151062.102337.897701325.297800.818809.733408.65090HepG2DDX6
CACNA2D4ENSG00000151062.10199.27540666.11930-1.7410038.9526037.18900HepG2DKC1
CACNA2D4ENSG00000151062.101035.22930690.483500.584208.318907.15340HepG2DNAJC21
CACNA2D4ENSG00000151062.10813.49230684.375000.249201.990901.42090HepG2DNAJC2
CACNA2D4ENSG00000151062.10342.28140680.23500-0.990909.090207.53700HepG2EEF2
CACNA2D4ENSG00000151062.10755.64640566.970600.414302.612001.53180HepG2EFTUD2
CACNA2D4ENSG00000151062.101265.50980568.786601.1537014.4852012.19720HepG2AGO1
CACNA2D4ENSG00000151062.101729.578701273.816800.441203.611502.93840HepG2EIF2S1
CACNA2D4ENSG00000151062.10976.55980552.134600.822608.540107.03480HepG2EIF3D
CACNA2D4ENSG00000151062.10238.48640583.17450-1.2900013.3363011.34070HepG2EIF3G
CACNA2D4ENSG00000151062.10255.563801407.60890-2.4615059.0815056.23040HepG2EIF4A3
CACNA2D4ENSG00000151062.101045.867501370.71170-0.390202.058501.46090HepG2EIF4B
CACNA2D4ENSG00000151062.10272.29020708.95730-1.3806013.9290011.80240HepG2ESF1
CACNA2D4ENSG00000151062.101319.464701520.03670-0.204201.823301.31430HepG2ETF1
CACNA2D4ENSG00000151062.10656.04310493.599000.410402.525001.41000HepG2FAM120A
CACNA2D4ENSG00000151062.101232.09320588.413101.0661019.8175017.32410HepG2FASTKD2
CACNA2D4ENSG00000151062.101779.76680826.587701.1063014.9584013.40520HepG2FIP1L1
CACNA2D4ENSG00000151062.10721.59160911.95730-0.337802.521301.76990HepG2FUBP3
CACNA2D4ENSG00000151062.10798.795001420.54650-0.8305010.544109.27870HepG2FXR1
CACNA2D4ENSG00000151062.10388.958701399.01890-1.8467042.7345039.70620HepG2G3BP2
CACNA2D4ENSG00000151062.10283.71890491.58540-0.793006.924105.51360HepG2GEMIN5
CACNA2D4ENSG00000151062.101221.48520788.810200.630806.097704.56250HepG2GNB2L1
CACNA2D4ENSG00000151062.10570.63960926.01620-0.698503.584902.31540HepG2GRSF1
CACNA2D4ENSG00000151062.10972.02310617.570500.654304.101902.21940HepG2GTF2F1
CACNA2D4ENSG00000151062.101471.58370664.709701.1465037.3292034.48820HepG2HDGF
CACNA2D4ENSG00000151062.101080.96460628.307700.782704.880502.99510HepG2HLTF
CACNA2D4ENSG00000151062.101440.34480846.559800.766604.225402.51150HepG2HNRNPA0
CACNA2D4ENSG00000151062.10139.32520697.09840-2.3229046.7199044.73620HepG2HNRNPA1
CACNA2D4ENSG00000151062.101751.382201079.355100.6982016.3192014.43390HepG2HNRNPA2B1
CACNA2D4ENSG00000151062.10447.36620775.38930-0.793508.511307.34710HepG2HNRNPC
CACNA2D4ENSG00000151062.10648.714601334.58480-1.0407016.6796015.11300HepG2HNRNPK
CACNA2D4ENSG00000151062.10649.705101069.76090-0.7194014.6594013.21750HepG2HNRNPL
CACNA2D4ENSG00000151062.101021.72870770.263200.407504.988704.19460HepG2HNRNPU
CACNA2D4ENSG00000151062.10697.81870850.93790-0.286201.942801.32780HepG2IGF2BP1
CACNA2D4ENSG00000151062.101270.39890786.799000.6911017.1723015.52990HepG2ILF2
CACNA2D4ENSG00000151062.101768.91190975.196100.859007.845605.56570HepG2ILF3
CACNA2D4ENSG00000151062.101052.95890636.449700.7262015.6882013.52260HepG2KIF1C
CACNA2D4ENSG00000151062.101068.95120772.826200.467904.068902.68320HepG2LARP7
CACNA2D4ENSG00000151062.10590.795201421.04390-1.2662021.2827019.55640HepG2MAGOH
CACNA2D4ENSG00000151062.10888.077601428.94390-0.686206.538905.60070HepG2MATR3
CACNA2D4ENSG00000151062.101011.30730668.677100.596705.819304.68890HepG2MSI2
CACNA2D4ENSG00000151062.10806.75000561.564500.522604.416802.88040HepG2NAA15
CACNA2D4ENSG00000151062.10884.024601462.56020-0.726307.866806.82380HepG2NCBP2
CACNA2D4ENSG00000151062.101888.512901164.539500.6974013.9526012.30250HepG2NOL12
CACNA2D4ENSG00000151062.10348.18770479.06390-0.460401.970801.33460HepG2NSUN2
CACNA2D4ENSG00000151062.101594.27890914.409500.801904.898503.68970HepG2PABPC1
CACNA2D4ENSG00000151062.101698.356801302.305900.383002.756202.03610HepG2PABPC4
CACNA2D4ENSG00000151062.101245.57490762.433400.7080013.9098012.25790HepG2PARN
CACNA2D4ENSG00000151062.101128.329901384.28450-0.295003.310002.65850HepG2PCBP1
CACNA2D4ENSG00000151062.10991.96620662.116200.583105.381902.98830HepG2PES1
CACNA2D4ENSG00000151062.10343.90760663.15080-0.9473014.9399013.36490HepG2PRPF4
CACNA2D4ENSG00000151062.101460.541901111.681400.393703.849303.15950HepG2PUF60
CACNA2D4ENSG00000151062.101659.147401180.130000.4914011.4064010.37380HepG2PUM1
CACNA2D4ENSG00000151062.10702.831601179.24870-0.7466011.3800010.06860HepG2PUM2
CACNA2D4ENSG00000151062.102468.461901525.484100.6942010.878909.75880HepG2QKI
CACNA2D4ENSG00000151062.101219.00010598.400901.026407.741406.59730HepG2RAVER1
CACNA2D4ENSG00000151062.101338.03150821.471600.7037011.196809.65280HepG2RBM15
CACNA2D4ENSG00000151062.101536.111501270.476000.273802.890302.36370HepG2RBM22
CACNA2D4ENSG00000151062.10959.548201384.49210-0.528906.228005.25380HepG2RBM25
CACNA2D4ENSG00000151062.10571.17840931.90740-0.706207.190505.58260HepG2RBM27
CACNA2D4ENSG00000151062.10427.62580756.75040-0.823507.108705.42190HepG2RCC2
CACNA2D4ENSG00000151062.10527.026301567.59940-1.5726059.1402057.41340HepG2NELFE
CACNA2D4ENSG00000151062.10487.080001460.03810-1.5838059.3544057.30530HepG2RECQL
CACNA2D4ENSG00000151062.10330.73530587.97220-0.830105.432104.13350HepG2RPS10
CACNA2D4ENSG00000151062.10479.01770859.45810-0.843309.648608.23180HepG2RPS2
CACNA2D4ENSG00000151062.10961.76500525.730500.871308.105206.84730HepG2RRP9
CACNA2D4ENSG00000151062.101164.05520685.955600.7629017.0777015.67280HepG2SAFB2
CACNA2D4ENSG00000151062.101365.51750946.462400.528703.816302.28450HepG2SART3
CACNA2D4ENSG00000151062.10119.41050625.62520-2.3894034.4710032.07400HepG2SF3A3
CACNA2D4ENSG00000151062.10846.792101466.47790-0.7923018.0374016.73020HepG2SF3B4
CACNA2D4ENSG00000151062.10837.588301065.99310-0.347904.019503.19800HepG2SLBP
CACNA2D4ENSG00000151062.101013.51340610.612800.730903.744802.61750HepG2SMNDC1
CACNA2D4ENSG00000151062.10769.02800302.721901.344905.253903.30270HepG2SNRNP200
CACNA2D4ENSG00000151062.101058.90420595.102600.831303.918302.98080HepG2SNRNP70
CACNA2D4ENSG00000151062.101990.836801434.967500.472309.601008.82160HepG2SRFBP1
CACNA2D4ENSG00000151062.10378.512901530.70110-2.0158090.8769089.05620HepG2SRSF1
CACNA2D4ENSG00000151062.101462.393901097.660800.413806.306305.41470HepG2SRSF5
CACNA2D4ENSG00000151062.101168.56730848.983900.460806.505905.51110HepG2SRSF7
CACNA2D4ENSG00000151062.101997.624101245.320400.6817018.5831017.38450HepG2SRSF9
CACNA2D4ENSG00000151062.10145.358901245.91180-3.09950150.51600148.34230HepG2SSB
CACNA2D4ENSG00000151062.101227.57540559.243901.1342011.013108.75630HepG2SUB1
CACNA2D4ENSG00000151062.101849.383301248.310800.5670013.8806012.66500HepG2SUCLG1
CACNA2D4ENSG00000151062.101755.484001246.665600.493703.292901.83690HepG2SUGP2
CACNA2D4ENSG00000151062.10810.86690557.886600.539404.640003.43880HepG2SUPT6H
CACNA2D4ENSG00000151062.10430.068201209.71400-1.4920011.718109.71640HepG2TBRG4
CACNA2D4ENSG00000151062.10922.90980459.793701.0051010.667108.96310HepG2TFIP11
CACNA2D4ENSG00000151062.10917.15170600.997200.609703.760502.05830HepG2TRA2A
CACNA2D4ENSG00000151062.101431.49330755.144300.9226025.7189024.21740HepG2TRIM56
CACNA2D4ENSG00000151062.10833.160401086.11650-0.382502.891901.99600HepG2TUFM
CACNA2D4ENSG00000151062.10498.99470706.91610-0.502503.350002.66430HepG2U2AF1
CACNA2D4ENSG00000151062.101838.133401149.670600.676904.175403.13660HepG2UBE2L3
CACNA2D4ENSG00000151062.101744.31780554.834601.6524080.2614077.70210HepG2UPF1
CACNA2D4ENSG00000151062.10367.56790628.06290-0.772905.404603.97370HepG2UPF2
CACNA2D4ENSG00000151062.10788.43240535.669900.557506.956806.08090HepG2UTP3
CACNA2D4ENSG00000151062.101415.79670900.321800.653005.023303.53020HepG2XPO5
CACNA2D4ENSG00000151062.10344.70320675.32720-0.9702010.505809.11150HepG2XRN2
CACNA2D4ENSG00000151062.10480.76940654.42840-0.444904.518003.69320HepG2ZC3H8
CACNA2D4ENSG00000151062.101378.20610610.210801.1753043.8636042.36320HepG2ZNF622
CACNA2D4ENSG00000151062.1079.710303.516604.5024018.1770016.56670K562EIF2S2
CACNA2D4ENSG00000151062.1013.459801.124503.581202.380001.63890K562HSPD1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CACNA2D4 is not available on ENCORE database.





14 RBPs can affect the splicing of CACNA2D4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.190000.000040.01809includedHepG2ILF3
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.184000.000620.01808includedHepG2HNRNPK
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.162000.000010.00181includedHepG2QKI
SECACNA2D4ENSG00000151062.10chr12-1910739191081019102081910284191944319195060.157000.000020.00356includedHepG2QKI
SECACNA2D4ENSG00000151062.10chr12-191073919108101910208191028419194431919506-0.169000.000040.00091excludedHepG2U2AF2
SECACNA2D4ENSG00000151062.10chr12-191970819197531919443191950619208271920893-0.169000.000620.05720excludedHepG2SRSF7
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.131000.002130.09129includedHepG2PTBP1
SECACNA2D4ENSG00000151062.10chr12-1910739191081019102081910284191944319195060.138000.000460.02827includedHepG2PTBP1
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.225000.000160.07639includedHepG2UPF1
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.136000.000750.06136includedHepG2DDX6
SECACNA2D4ENSG00000151062.10chr12-1910739191081019102081910284191944319195060.205000.000090.01598includedHepG2PCBP2
SECACNA2D4ENSG00000151062.10chr12-191073919108101910208191028419194431919506-0.192000.000120.02521excludedHepG2HNRNPUL1
SECACNA2D4ENSG00000151062.10chr12-1910739191081019102081910284191944319195060.184000.001690.03882includedHepG2SRSF1
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.174000.000090.02454includedHepG2DDX55
SECACNA2D4ENSG00000151062.10chr12-1910739191081019102081910284191944319195060.178000.000090.02506includedHepG2DDX55
SECACNA2D4ENSG00000151062.10chr12-1919708191975319194431919506192082719208930.304000.000000.00013includedHepG2XRCC6
SECACNA2D4ENSG00000151062.10chr12-191073919108101910208191028419194431919506-0.111000.000440.09916excludedHepG2DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CACNA2D4 is not avaliable on ENCORE database.