SH3GL3

General Information

Gene Name       : SH3GL3
Gene ID             : ENSG00000140600.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SH3GL3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SH3GL3ENSG00000140600.160.000.000.00ENCSR000AEF
HepG2SH3GL3ENSG00000140600.160.000.000.00ENCSR985KAT
K562SH3GL3ENSG00000140600.169.609.639.62ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SH3GL3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SH3GL3 RNA is bound by 12 proteins.  







eCLIP assay for SH3GL3 is not avaliable on ENCORE database.





12 proteins are bound to SH3GL3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr158424548384245579+3'-UTR,CDS,intron-Proximal3.327803.28806K562KHSRP
chr158428723384287332+3'-UTR4.784946.07567K562KHSRP
chr158423736284237435+3'-UTR,CDS,intron-Proximal3.475843.66187K562ZNF622
chr158421397184214035+intron-Distal3.767293.06015K562MATR3
chr158412883284128923+intron-Distal4.4462110.67746K562ILF3
chr158420941184209487+intron-Distal3.838823.02234K562KHSRP
chr158419848084198566+intron-Distal3.957255.20902K562EXOSC5
chr158413549384135625+intron-Distal3.765044.74253K562KHSRP
chr158419780984197943+intron-Distal5.196499.47773K562HNRNPM
chr158418751584187557+intron-Distal4.683845.76606K562EXOSC5
chr158421210684212160+intron-Distal4.235283.30687K562EXOSC5
chr158418725984187297+intron-Distal4.164773.59909K562EXOSC5
chr158423513684235222+intron-Distal3.479735.17677K562EIF4G2
chr158423082484230897+intron-Distal3.803353.19036K562HNRNPL
chr158419247184192553+intron-Distal4.793323.55787K562PTBP1
chr158418766684187744+intron-Distal4.232356.10949K562EXOSC5
chr158416576084165818+intron-Distal4.137623.23532K562MATR3
chr158421634884216403+intron-Distal4.372174.78076K562HNRNPM
chr158421173284211779+intron-Distal4.682274.80466K562EXOSC5
chr158423645484236523+intron-Distal4.813615.97091K562TARDBP
chr158419779784197900+intron-Distal3.449584.74379K562EXOSC5
chr158418790084188003+intron-Distal5.386248.69609K562EXOSC5
chr158411720784117275+intron-Distal4.176638.49253K562TARDBP
chr158423072184230805+intron-Distal3.313204.64655K562HNRNPL
chr158419819884198263+intron-Distal3.743984.91037K562EXOSC5
chr158413081084130917+intron-Distal4.042397.22647K562QKI
chr158411691984116986+intron-Distal3.723703.07008K562NONO
chr158413303284133162+intron-Distal4.999808.08294K562MATR3
chr158412941184129515+intron-Distal4.251803.42844K562KHSRP
chr158420891384209017+intron-Distal3.853693.68839K562KHSRP
chr158411662284116709+intron-Distal3.840933.30664K562NONO
chr158414131284141409+intron-Distal4.294513.47525K562MATR3
chr158421104884211125+intron-Distal4.428794.80466K562EXOSC5
chr158419411384194209+intron-Distal4.783296.41216K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SH3GL3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SH3GL3 is not available on ENCORE database.

  • 32 RBPs can affect the levels of SH3GL3.  








The Knockdown/knockout RNA-Seq assay for SH3GL3 is not available on ENCORE database.





32 RBPs can affect the gene expression of SH3GL3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SH3GL3ENSG00000140600.12210.61900314.51570-0.578503.047001.75640K562ABCF1
SH3GL3ENSG00000140600.12258.46530399.38780-0.627804.897804.17800K562AGGF1
SH3GL3ENSG00000140600.12319.54550415.57760-0.379101.961801.40900K562AKAP8L
SH3GL3ENSG00000140600.12258.28370350.83420-0.441802.156001.62670K562AQR
SH3GL3ENSG00000140600.12245.09580167.263000.551102.520001.77050K562CPSF6
SH3GL3ENSG00000140600.12585.85500434.864800.429903.044302.02300K562CELF1
SH3GL3ENSG00000140600.12540.90440270.782400.9981014.3461012.97690K562DDX47
SH3GL3ENSG00000140600.12217.76500128.404400.762003.238402.24540K562EFTUD2
SH3GL3ENSG00000140600.12309.12790226.076700.451302.034401.30350K562FIP1L1
SH3GL3ENSG00000140600.12304.38550212.667100.517202.164901.55070K562G3BP2
SH3GL3ENSG00000140600.12448.28700292.574000.615504.140303.21900K562GRSF1
SH3GL3ENSG00000140600.12173.93460272.96840-0.650203.169301.83930K562HNRNPK
SH3GL3ENSG00000140600.12470.78780306.518100.619004.244803.26510K562HSPD1
SH3GL3ENSG00000140600.12182.95930286.64010-0.647703.994602.87140K562MATR3
SH3GL3ENSG00000140600.12494.27530377.020200.390602.352801.31570K562MSI2
SH3GL3ENSG00000140600.12415.93800255.561600.702605.142303.79880K562PCBP2
SH3GL3ENSG00000140600.12536.14330221.794401.2733013.4599011.64720K562PCBP3
SH3GL3ENSG00000140600.12432.02400170.129601.3444016.7038014.81930K562POLR2G
SH3GL3ENSG00000140600.12419.99480279.034000.589804.537303.70710K562PTBP1
SH3GL3ENSG00000140600.12346.34410202.919800.771203.439201.82330K562RAVER1
SH3GL3ENSG00000140600.1274.37980157.99640-1.086905.186203.82260K562RCC2
SH3GL3ENSG00000140600.12194.22830127.320000.609202.348901.59860K562RPS19
SH3GL3ENSG00000140600.12207.47550127.804400.698902.793101.45990K562RRP9
SH3GL3ENSG00000140600.12214.71900449.94290-1.067304.944203.00430K562SFPQ
SH3GL3ENSG00000140600.12343.67550234.375800.552103.784502.70890K562SRPK2
SH3GL3ENSG00000140600.12217.44870145.609800.578503.048801.81560K562SRSF7
SH3GL3ENSG00000140600.12279.84380193.655400.531002.885501.33150K562SRSF9
SH3GL3ENSG00000140600.12499.21840336.724700.568004.762502.84110K562SUCLG1
SH3GL3ENSG00000140600.12216.75190121.057300.840304.225202.94580K562SUPV3L1
SH3GL3ENSG00000140600.12324.46460128.085201.3409010.796108.73400K562UCHL5
SH3GL3ENSG00000140600.12333.71260218.735200.609304.666703.59050K562WDR43
SH3GL3ENSG00000140600.12606.76450415.739000.545404.483502.83010K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SH3GL3 is not available on ENCORE database.





11 RBPs can affect the splicing of SH3GL3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESH3GL3ENSG00000140600.12chr15+842561098425624284255734842558388425741384257523-0.143000.000010.00051excludedK562SRSF1
SESH3GL3ENSG00000140600.12chr15+842780218427821884257413842575238428683384287394-0.120000.003920.06226excludedK562SRSF1
SESH3GL3ENSG00000140600.12chr15+8425610984256242842557348425583884257413842575230.204000.000800.02624includedK562AKAP8L
SESH3GL3ENSG00000140600.12chr15+8427802184278218842574138425752384286833842874030.109000.001760.04873includedK562AKAP8L
SESH3GL3ENSG00000140600.12chr15+842561098425624284255734842558388425741384257523-0.174000.002060.06799excludedK562FXR1
SESH3GL3ENSG00000140600.12chr15+8427802184278218842574138425752384286833842873940.246000.000010.00549includedK562HNRNPA1
SESH3GL3ENSG00000140600.12chr15+8427802184278218842574138425752384286833842873940.069000.000140.03275includedK562LARP4
SESH3GL3ENSG00000140600.12chr15+842780218427821884257413842575238428683384287403-0.140000.000170.00942excludedK562TARDBP
SESH3GL3ENSG00000140600.12chr15+8425610984256242842557348425583884257413842575230.410000.000100.00585includedK562HNRNPU
SESH3GL3ENSG00000140600.12chr15+8427802184278218842574138425752384286833842874030.113000.003550.07047includedK562RBM15
SESH3GL3ENSG00000140600.12chr15+8425610984256242842557348425583884257413842575230.301000.000080.00363includedK562RBM15
SESH3GL3ENSG00000140600.12chr15+8427802184278218842574138425752384286833842874030.116000.001080.02960includedK562AGGF1
SESH3GL3ENSG00000140600.12chr15+8425610984256242842557348425583884257413842575230.557000.000000.00003includedK562HNRNPK
SESH3GL3ENSG00000140600.12chr15+842561098425624284255734842558388425741384257523-0.124000.000010.00086excludedK562PTBP1
SESH3GL3ENSG00000140600.12chr15+842780218427821884257413842575238428683384287394-0.124000.000610.02720excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SH3GL3 is not avaliable on ENCORE database.