NME6

General Information

Gene Name       : NME6
Gene ID             : ENSG00000172113.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NME6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NME6ENSG00000172113.914.1721.5817.88ENCSR000AEF
HepG2NME6ENSG00000172113.925.6820.7523.21ENCSR985KAT
K562NME6ENSG00000172113.926.1328.2227.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NME6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NME6 RNA is bound by 4 proteins.  







eCLIP assay for NME6 is not avaliable on ENCORE database.





4 proteins are bound to NME6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr34833753748337655-3'-UTR,CDS,intron-Distal,intron-Proximal4.223463.85435K562PRPF8
chr34833991648340016-5'-UTR,CDS,intron-Distal,intron-Proximal4.164225.07098K562DDX3X
chr34834259548342712-intron-Distal3.757186.62272HepG2EFTUD2
chr34834249448342545-intron-Distal3.814013.60940HepG2HNRNPC
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NME6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NME6 is not available on ENCORE database.

  • 30 RBPs can affect the levels of NME6.  








The Knockdown/knockout RNA-Seq assay for NME6 is not available on ENCORE database.





30 RBPs can affect the gene expression of NME6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NME6ENSG00000172113.4324.17300200.658700.691903.140202.13500HepG2ABCF1
NME6ENSG00000172113.4353.01520483.96830-0.455203.575102.81170HepG2AUH
NME6ENSG00000172113.4525.29270317.153700.727805.081404.21770HepG2EIF4A3
NME6ENSG00000172113.4262.42360354.06650-0.432102.091601.37630HepG2EIF4G2
NME6ENSG00000172113.4208.74460139.780700.578502.411401.52250HepG2HNRNPM
NME6ENSG00000172113.4549.89730319.989700.781006.215705.24100HepG2MAGOH
NME6ENSG00000172113.4124.22460215.81130-0.796804.859903.86560HepG2PRPF4
NME6ENSG00000172113.4283.33850365.78580-0.368501.887701.35620HepG2QKI
NME6ENSG00000172113.4459.14830343.890500.416902.476101.82450HepG2RPLP0
NME6ENSG00000172113.4391.29460524.56180-0.422903.314002.78130HepG2SRFBP1
NME6ENSG00000172113.4247.87870329.87740-0.412302.262901.74710HepG2TAF15
NME6ENSG00000172113.4254.66150188.195000.436301.908801.47610HepG2TIAL1
NME6ENSG00000172113.4196.84690297.39990-0.595303.495202.87030K562AGGF1
NME6ENSG00000172113.4203.22040309.44550-0.606603.115002.42110K562AKAP8L
NME6ENSG00000172113.4238.29060324.65910-0.446202.512301.64430K562ATP5C1
NME6ENSG00000172113.4500.31270317.678700.655206.682605.73420K562DDX47
NME6ENSG00000172113.4243.60860333.06430-0.451202.448701.63120K562DKC1
NME6ENSG00000172113.4439.15340207.038901.0847011.381109.68730K562EIF4A3
NME6ENSG00000172113.4393.07310215.311400.868308.265407.29030K562FXR1
NME6ENSG00000172113.4193.33440328.44300-0.764503.351602.43400K562KIF1C
NME6ENSG00000172113.4200.32880314.36510-0.650103.672102.37440K562MAK16
NME6ENSG00000172113.4238.81260367.93300-0.623602.797101.88250K562MBNL1
NME6ENSG00000172113.4129.85090257.89050-0.989905.087703.77010K562NAA15
NME6ENSG00000172113.4375.34130271.168100.468902.900602.22310K562PTBP1
NME6ENSG00000172113.4144.00090306.97490-1.092007.338506.50030K562PUS1
NME6ENSG00000172113.4167.05620299.02630-0.839905.048004.26870K562RBM15
NME6ENSG00000172113.4427.65310290.588200.557402.808901.98620K562RPS19
NME6ENSG00000172113.4298.38130170.464700.807602.783101.47870K562SFPQ
NME6ENSG00000172113.479.47490160.60480-1.014903.081401.75850K562SNRNP200
NME6ENSG00000172113.4369.51500265.862700.474902.669901.97380K562SRSF1
NME6ENSG00000172113.4441.28480560.35990-0.344602.079801.34300K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NME6 is not available on ENCORE database.





10 RBPs can affect the splicing of NME6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENME6ENSG00000172113.4chr3-483420164834212448339916483400134834284248342877-0.587000.000080.05404excludedHepG2NKRF
SENME6ENSG00000172113.4chr3-483376084833764848336564483367254833821648338304-0.363000.000080.02577excludedHepG2DKC1
SENME6ENSG00000172113.4chr3-483420164834212448339916483400134834284248342877-0.563000.000180.02053excludedHepG2TBRG4
SENME6ENSG00000172113.4chr3-4834206648342124483395964834001348342768483427950.150000.000800.08007includedHepG2SSB
SENME6ENSG00000172113.4chr3-483376084833764848336564483367254833821648338319-0.535000.000000.00002excludedK562SF3B1
MXENME6ENSG00000172113.4chr3-4833656448336725483399164834001348334753483362934834278548342848-0.284000.004280.064472includedHepG2U2AF1
MXENME6ENSG00000172113.4chr3-48337608483376484833821648338319483365644833672548339916483400130.192000.000400.011091includedHepG2SRSF1
MXENME6ENSG00000172113.4chr3-48337608483376484833821648338319483365644833672548339916483400130.280000.000090.005501includedHepG2TAF15
MXENME6ENSG00000172113.4chr3-4833760848337648483382164833831948336564483367254833991648340013-0.213000.000020.008472includedK562ZC3H8
MXENME6ENSG00000172113.4chr3-4833656448336725483382164833831948335590483362934833991648340013-0.175000.008740.088802includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NME6 is not avaliable on ENCORE database.