KLHL7

General Information

Gene Name       : KLHL7
Gene ID             : ENSG00000122550.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL7ENSG00000122550.1715.4311.1713.30ENCSR000AEF
HepG2KLHL7ENSG00000122550.1713.2319.4516.34ENCSR985KAT
K562KLHL7ENSG00000122550.1721.2522.8822.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL7 RNA is bound by 6 proteins.  







eCLIP assay for KLHL7 is not avaliable on ENCORE database.





6 proteins are bound to KLHL7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr72316541523165508+3'-UTR,CDS,intron-Distal4.127445.47880HepG2SUB1
chr72318038523180440+3'-UTR,CDS,intron-Proximal4.187843.71570HepG2BCLAF1
chr72316540723165538+3'-UTR,CDS,intron-Distal3.349474.91258K562YBX3
chr72316475323164796+5'-UTR,CDS,intron-Distal,intron-Proximal4.256603.06595HepG2BCLAF1
chr72314540423145685+5'-UTR,CDS4.363707.24138K562FXR2
chr72316466623164735+5'-UTR,CDS,intron-Distal,intron-Proximal4.014124.31428K562YBX3
chr72314545423145562+5'-UTR5.247977.46114HepG2DDX3X
chr72316435723164401+5'-UTR,CDS,intron-Distal,intron-Proximal3.895603.65750K562YBX3
chr72314541723145655+5'-UTR,CDS4.7706310.63554K562DDX3X
chr72314544323145542+5'-UTR3.427104.31744K562YBX3
chr72314962323149676+intron-Distal3.761063.04224HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL7 is not available on ENCORE database.

  • 42 RBPs can affect the levels of KLHL7.  








The Knockdown/knockout RNA-Seq assay for KLHL7 is not available on ENCORE database.





42 RBPs can affect the gene expression of KLHL7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL7ENSG00000122550.13245.99530445.46190-0.856704.833703.59270HepG2BCCIP
KLHL7ENSG00000122550.13155.32710388.11140-1.321203.446702.78700HepG2BOP1
KLHL7ENSG00000122550.13198.40270354.30980-0.836607.126705.50940HepG2YBX3
KLHL7ENSG00000122550.13236.88400352.07770-0.571703.385802.64080HepG2DDX21
KLHL7ENSG00000122550.13478.05820643.46490-0.428702.255301.69210HepG2DDX6
KLHL7ENSG00000122550.13303.96250618.51450-1.0249010.400209.29690HepG2EIF2S1
KLHL7ENSG00000122550.13252.60380683.50020-1.4361018.2272016.59980HepG2EIF4A3
KLHL7ENSG00000122550.13496.94010754.21280-0.601907.112206.22350HepG2ETF1
KLHL7ENSG00000122550.13423.47910639.76410-0.595204.167603.36090HepG2G3BP1
KLHL7ENSG00000122550.13191.28760404.00560-1.078602.610401.98610HepG2GPKOW
KLHL7ENSG00000122550.13206.33350390.71000-0.921107.151606.07650HepG2HNRNPC
KLHL7ENSG00000122550.13380.09000647.93420-0.769507.006905.93150HepG2HNRNPK
KLHL7ENSG00000122550.13484.58380589.03800-0.281602.121001.52100HepG2HNRNPL
KLHL7ENSG00000122550.13309.35650388.12820-0.327301.855301.34980HepG2HNRNPU
KLHL7ENSG00000122550.13472.06700650.28870-0.462102.964002.26920HepG2IGF2BP2
KLHL7ENSG00000122550.13517.81700689.95790-0.414102.451901.83340HepG2MAGOH
KLHL7ENSG00000122550.13507.36830710.13490-0.485103.034102.37240HepG2NCBP2
KLHL7ENSG00000122550.13484.85000641.20170-0.403203.181802.36600HepG2NOL12
KLHL7ENSG00000122550.13361.82700632.36460-0.805507.118705.97120HepG2PABPC4
KLHL7ENSG00000122550.13467.10660622.36120-0.414003.731503.04880HepG2PCBP1
KLHL7ENSG00000122550.13204.39810338.01180-0.725703.233902.36740HepG2PRPF8
KLHL7ENSG00000122550.13462.83450649.74750-0.489405.628004.84470HepG2PUM1
KLHL7ENSG00000122550.13494.64070685.87590-0.471604.153503.41000HepG2QKI
KLHL7ENSG00000122550.131023.27630630.387500.6988010.708409.83540HepG2RBM22
KLHL7ENSG00000122550.13233.75790345.65530-0.564304.150403.38900HepG2SAFB2
KLHL7ENSG00000122550.13525.82030659.33810-0.326402.508301.94110HepG2SF3B4
KLHL7ENSG00000122550.13895.09990712.008700.330103.288602.75730HepG2SRFBP1
KLHL7ENSG00000122550.13823.34910688.190400.258601.827701.42080HepG2SRSF1
KLHL7ENSG00000122550.13439.17210559.86590-0.350302.803702.24940HepG2SRSF9
KLHL7ENSG00000122550.13890.06220618.208300.525707.271806.51640HepG2SSB
KLHL7ENSG00000122550.13242.88710380.50630-0.647605.669504.91480HepG2TRIM56
KLHL7ENSG00000122550.13178.45820257.60480-0.529602.067601.41090HepG2UCHL5
KLHL7ENSG00000122550.13560.06270415.195300.431703.683803.04620K562AGGF1
KLHL7ENSG00000122550.13615.88190432.037500.511404.123503.32360K562AKAP8L
KLHL7ENSG00000122550.13577.14500453.326200.348302.675601.77820K562ATP5C1
KLHL7ENSG00000122550.13450.42850336.996600.418501.886501.31510K562G3BP2
KLHL7ENSG00000122550.13150.86100275.69650-0.869905.372404.56610K562HNRNPC
KLHL7ENSG00000122550.13165.30750246.18350-0.574602.558801.46750K562HNRNPF
KLHL7ENSG00000122550.13159.35120279.58970-0.811104.913302.84120K562LIN28B
KLHL7ENSG00000122550.13162.04030247.18690-0.609202.864501.94170K562PSIP1
KLHL7ENSG00000122550.13708.44330428.406100.725606.947206.13220K562PUS1
KLHL7ENSG00000122550.13560.97980417.464000.426202.567901.99330K562RBM15
KLHL7ENSG00000122550.13157.58370225.50760-0.517102.182701.30650K562RCC2
KLHL7ENSG00000122550.13174.79650252.56310-0.531002.250401.41020K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL7 is not available on ENCORE database.





5 RBPs can affect the splicing of KLHL7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHL7ENSG00000122550.13chr7+2316533623165418231646662316479123180387231805630.096000.004950.04615includedK562AQR
SEKLHL7ENSG00000122550.13chr7+2314624723146413231454082314576523163395231634980.108000.000010.00016includedK562AQR
SEKLHL7ENSG00000122550.13chr7+231574262315758323146274231464132316339523163498-0.592000.005860.05296excludedK562AQR
SEKLHL7ENSG00000122550.13chr7+2315745223157583231453762314576523163395231634980.275000.000080.01069includedK562SUPV3L1
SEKLHL7ENSG00000122550.13chr7+2316537923165418231646662316479123180387231805630.197000.000200.00438includedK562PUS1
SEKLHL7ENSG00000122550.13chr7+2316537923165418231646662316479123180387231805630.229000.001980.04373includedHepG2SRSF1
SEKLHL7ENSG00000122550.13chr7+231574522315758323145376231457652316339523163498-0.081000.003580.09830excludedK562HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL7 is not avaliable on ENCORE database.