DEPDC5

General Information

Gene Name       : DEPDC5
Gene ID             : ENSG00000100150.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DEPDC5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DEPDC5ENSG00000100150.1714.6713.1813.93ENCSR000AEF
HepG2DEPDC5ENSG00000100150.178.466.677.57ENCSR985KAT
K562DEPDC5ENSG00000100150.176.246.416.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DEPDC5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DEPDC5 RNA is bound by 8 proteins.  







eCLIP assay for DEPDC5 is not avaliable on ENCORE database.





8 proteins are bound to DEPDC5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223227570132275804+3'-UTR,CDS,intron-Proximal4.566475.01842HepG2PRPF8
chr223216260432162657+3'-UTR,CDS,intron-Distal,intron-Proximal4.316383.82843HepG2PPIG
chr223216479832164847+3'-UTR,CDS,intron-Proximal4.195873.16051HepG2PPIG
chr223216257032162592+3'-UTR,CDS,intron-Distal,intron-Proximal4.077363.49905HepG2PPIG
chr223216102432161047+5'-UTR,CDS,intron-Proximal4.593163.59565K562DDX24
chr223216096032161000+5'-UTR,CDS,intron-Proximal4.365745.23082K562DDX24
chr223215664132156690+5'-UTR,CDS,intron-Proximal5.468965.93845K562DDX24
chr223215664132156689+5'-UTR,CDS,intron-Proximal4.316383.20743HepG2PPIG
chr223216101532161048+5'-UTR,CDS,intron-Proximal3.590124.68902HepG2PPIG
chr223215003132150153+5'-UTR,intron-Distal,intron-Proximal3.265163.52645HepG2NCBP2
chr223218873832188799+CDS4.531784.84481HepG2PPIG
chr223218081032180863+CDS,intron-Proximal4.593114.78529HepG2BCLAF1
chr223218801132188064+CDS,intron-Proximal4.616744.67689HepG2PPIG
chr223218875532188799+CDS4.080343.02457HepG2BCLAF1
chr223223285232232973+CDS,intron-Distal,intron-Proximal4.569663.78681HepG2PCBP2
chr223218801632188045+CDS,intron-Proximal4.026883.02457HepG2BCLAF1
chr223223251032232630+intron-Distal4.212083.97974HepG2RBFOX2
chr223223264232232765+intron-Distal3.958603.45219HepG2RBFOX2
chr223225217632252276+intron-Distal4.992146.56347K562AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DEPDC5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DEPDC5 is not available on ENCORE database.

  • 24 RBPs can affect the levels of DEPDC5.  








The Knockdown/knockout RNA-Seq assay for DEPDC5 is not available on ENCORE database.





24 RBPs can affect the gene expression of DEPDC5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DEPDC5ENSG00000100150.12476.98990321.661600.568303.003502.45180HepG2AKAP1
DEPDC5ENSG00000100150.12424.11500252.869000.746005.222004.17720HepG2CIRBP
DEPDC5ENSG00000100150.12453.24720281.271800.688204.465403.65620HepG2EIF4A3
DEPDC5ENSG00000100150.12583.63520442.912600.397902.827802.22150HepG2ETF1
DEPDC5ENSG00000100150.12191.67570255.88050-0.416802.115801.57750HepG2HNRNPU
DEPDC5ENSG00000100150.12403.38620267.570000.592103.411202.66940HepG2IGF2BP2
DEPDC5ENSG00000100150.12208.87090291.57580-0.481302.677002.07810HepG2PCBP1
DEPDC5ENSG00000100150.12257.59890146.709800.812103.926502.97480HepG2RPS3A
DEPDC5ENSG00000100150.12344.34470257.292200.420301.978001.37560HepG2SF3B1
DEPDC5ENSG00000100150.12392.71670276.829400.504402.282601.38330HepG2SRSF3
DEPDC5ENSG00000100150.12178.85700262.30820-0.552503.209402.62420HepG2SRSF9
DEPDC5ENSG00000100150.12575.76230362.993600.665407.671406.90030HepG2SSB
DEPDC5ENSG00000100150.12491.72180258.184200.929304.185002.89190HepG2TBRG4
DEPDC5ENSG00000100150.12355.74340248.640900.516703.234402.70030HepG2TIAL1
DEPDC5ENSG00000100150.12331.12900412.17340-0.315902.003401.51760HepG2ZNF622
DEPDC5ENSG00000100150.12515.11610379.899300.439202.615401.40930K562APOBEC3C
DEPDC5ENSG00000100150.12260.50170364.10230-0.483102.437201.88040K562AQR
DEPDC5ENSG00000100150.12240.37050148.792700.691903.755902.80440K562EIF4A3
DEPDC5ENSG00000100150.12214.33340154.738400.469901.996601.46630K562FXR1
DEPDC5ENSG00000100150.12286.37370391.08570-0.449602.375401.67360K562GRSF1
DEPDC5ENSG00000100150.12182.11610270.80450-0.572403.195302.23830K562HNRNPU
DEPDC5ENSG00000100150.12233.45760326.51460-0.484002.562401.77810K562PPIG
DEPDC5ENSG00000100150.12313.66780469.74540-0.582603.308602.41760K562PUF60
DEPDC5ENSG00000100150.12152.16820261.11990-0.779004.884104.11690K562RBM15
DEPDC5ENSG00000100150.12117.47200189.61870-0.690802.018701.32690K562RPS19
DEPDC5ENSG00000100150.12301.52330410.19940-0.444102.583801.75530K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DEPDC5 is not available on ENCORE database.





3 RBPs can affect the splicing of DEPDC5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSDEPDC5ENSG00000100150.12chr22+3223295732233141322329843223314132229900322299660.376000.002800.06017longerHepG2U2AF2
A3SSDEPDC5ENSG00000100150.12chr22+3215451232154619321545313215461932150847321509650.123000.016700.08189longerK562AQR
MXEDEPDC5ENSG00000100150.12chr22+3222990032229966322329843223314132218678322187763223467032234831-0.372000.004800.085232includedK562SBDS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DEPDC5 is not avaliable on ENCORE database.