COMMD2

General Information

Gene Name       : COMMD2
Gene ID             : ENSG00000114744.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: COMMD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COMMD2ENSG00000114744.844.4737.3740.92ENCSR000AEF
HepG2COMMD2ENSG00000114744.820.0239.4829.75ENCSR985KAT
K562COMMD2ENSG00000114744.842.6145.8444.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COMMD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COMMD2 RNA is bound by 3 proteins.  







eCLIP assay for COMMD2 is not avaliable on ENCORE database.





3 proteins are bound to COMMD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3149458576149458679-3'-UTR,intron-Distal5.959019.17142K562PUM2
chr3149459369149459468-3'-UTR,CDS,intron-Distal3.081883.07714K562YBX3
chr3149470168149470267-5'-UTR,CDS,intron-Distal,intron-Proximal3.910416.82597K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COMMD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COMMD2 is not available on ENCORE database.

  • 50 RBPs can affect the levels of COMMD2.  








The Knockdown/knockout RNA-Seq assay for COMMD2 is not available on ENCORE database.





50 RBPs can affect the gene expression of COMMD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COMMD2ENSG00000114744.4308.69350494.94290-0.681104.757303.87660HepG2CPSF6
COMMD2ENSG00000114744.4420.97250317.140700.408502.419201.41100HepG2CSTF2
COMMD2ENSG00000114744.4254.02380382.40960-0.590203.139401.65210HepG2DDX28
COMMD2ENSG00000114744.41207.04510869.691900.472803.589702.88820HepG2DDX3X
COMMD2ENSG00000114744.4468.03160747.01940-0.674505.011404.20190HepG2DDX6
COMMD2ENSG00000114744.4626.18410479.153700.386003.139202.42460HepG2DKC1
COMMD2ENSG00000114744.4344.22260460.61290-0.420202.901502.18440HepG2DNAJC21
COMMD2ENSG00000114744.4613.24210418.224200.552103.607602.56370HepG2EEF2
COMMD2ENSG00000114744.4211.32140718.19140-1.7649027.6344025.89200HepG2EIF2S1
COMMD2ENSG00000114744.4260.48610471.14090-0.855007.925306.07050HepG2EIF2S2
COMMD2ENSG00000114744.4701.55010537.983200.382902.526301.48280HepG2ESF1
COMMD2ENSG00000114744.4505.13640816.15550-0.692209.629208.61670HepG2ETF1
COMMD2ENSG00000114744.4624.84820800.73380-0.357802.057201.45690HepG2FXR1
COMMD2ENSG00000114744.4471.26890742.84690-0.656505.182304.28460HepG2G3BP1
COMMD2ENSG00000114744.4486.35370302.261000.686105.048303.83460HepG2GEMIN5
COMMD2ENSG00000114744.4345.64530536.16190-0.633403.323601.59180HepG2GTF2F1
COMMD2ENSG00000114744.4794.15970465.025600.772005.996405.09560HepG2HNRNPA1
COMMD2ENSG00000114744.4519.95270752.08570-0.532504.055403.22370HepG2HNRNPK
COMMD2ENSG00000114744.4356.36890457.80790-0.361402.661801.65910HepG2KIF1C
COMMD2ENSG00000114744.4507.47420805.51130-0.666605.086104.25420HepG2MATR3
COMMD2ENSG00000114744.4286.43950734.32560-1.3582018.3821016.57470HepG2PABPC4
COMMD2ENSG00000114744.4346.00920458.29770-0.405502.785702.04640HepG2PPIL4
COMMD2ENSG00000114744.4581.97400421.725900.464504.206703.27530HepG2PRPF4
COMMD2ENSG00000114744.4832.04500566.289000.555003.017201.75100HepG2PRPF6
COMMD2ENSG00000114744.4542.68630389.443200.478603.006302.16700HepG2PRPF8
COMMD2ENSG00000114744.41067.02760682.162900.645309.318208.49500HepG2RBM22
COMMD2ENSG00000114744.4345.46510503.36030-0.543103.323002.44630HepG2RPS2
COMMD2ENSG00000114744.4346.93550513.81030-0.566603.480102.27100HepG2RPS5
COMMD2ENSG00000114744.4365.78450457.59220-0.323102.108001.53290HepG2SAFB2
COMMD2ENSG00000114744.41072.18600588.592500.865107.856706.67950HepG2SF3A3
COMMD2ENSG00000114744.4596.27960738.08470-0.307802.408101.85060HepG2SF3B4
COMMD2ENSG00000114744.41025.17510770.492000.411905.361504.72700HepG2SRFBP1
COMMD2ENSG00000114744.41017.66310770.398800.401504.377003.81540HepG2SRSF1
COMMD2ENSG00000114744.4890.38040668.994000.412304.827604.18670HepG2SSB
COMMD2ENSG00000114744.4317.44310423.50640-0.415902.288401.42770HepG2SUPT6H
COMMD2ENSG00000114744.4372.65490503.74620-0.434903.652303.02340HepG2TRIM56
COMMD2ENSG00000114744.4798.26400536.456700.573304.694903.88820HepG2U2AF1
COMMD2ENSG00000114744.4137.13920296.83480-1.114008.163406.86250HepG2UCHL5
COMMD2ENSG00000114744.4623.59130503.962800.307202.080101.54610HepG2UTP3
COMMD2ENSG00000114744.4606.20740416.187500.542506.023205.09230HepG2ZC3H8
COMMD2ENSG00000114744.4791.19930574.091100.462705.940505.21860HepG2ZNF622
COMMD2ENSG00000114744.4476.63560806.08930-0.758107.937806.59510K562CPSF6
COMMD2ENSG00000114744.4365.80690547.21440-0.581005.863104.07230K562EIF2S1
COMMD2ENSG00000114744.4451.10390876.91960-0.9590014.4966013.04760K562EIF2S2
COMMD2ENSG00000114744.4777.01770541.275300.521505.765004.93830K562FXR1
COMMD2ENSG00000114744.4912.56010577.701200.659504.903403.90030K562G3BP2
COMMD2ENSG00000114744.4522.88540769.64430-0.557702.438501.69150K562GPKOW
COMMD2ENSG00000114744.41645.672601221.195700.430303.937202.99220K562HSPD1
COMMD2ENSG00000114744.4541.35560767.43470-0.503504.358203.17710K562MATR3
COMMD2ENSG00000114744.4698.72000832.39300-0.252602.339901.64850K562NSUN2
COMMD2ENSG00000114744.4756.85430527.456800.520903.815402.93570K562PRPF8
COMMD2ENSG00000114744.41192.40040890.196200.421603.181102.60570K562PUS1
COMMD2ENSG00000114744.4335.67030474.58180-0.499603.012601.93060K562SRFBP1
COMMD2ENSG00000114744.4331.50550510.64080-0.623304.055902.80730K562SUPV3L1
COMMD2ENSG00000114744.4720.07710571.635600.333002.402301.63780K562SYNCRIP
COMMD2ENSG00000114744.4449.67570741.23660-0.721007.150405.95550K562TARDBP
COMMD2ENSG00000114744.4567.08310714.98340-0.334302.239501.51010K562TIA1
COMMD2ENSG00000114744.4854.85910560.504700.608904.576203.10080K562U2AF1
COMMD2ENSG00000114744.4383.61390540.47610-0.494603.057501.98190K562UCHL5
COMMD2ENSG00000114744.41029.767601270.07060-0.302602.296401.52230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COMMD2 is not available on ENCORE database.





9 RBPs can affect the splicing of COMMD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.134000.000000.00000includedK562SRSF1
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.052000.000370.03368includedHepG2DDX3X
SECOMMD2ENSG00000114744.4chr3-149469996149470074149469109149469272149470164149470237-0.347000.000250.00723excludedK562U2AF1
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.052000.001100.08123includedHepG2DDX6
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.060000.000010.00419includedHepG2CDC40
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.077000.000050.00425includedHepG2SF3B4
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.058000.000950.09946includedK562RBM22
SECOMMD2ENSG00000114744.4chr3-149469996149470074149469109149469272149470164149470237-0.415000.000030.00109excludedK562U2AF2
SECOMMD2ENSG00000114744.4chr3-1494680431494681691494591761494595051494684641494686380.069000.000010.00027includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COMMD2 is not avaliable on ENCORE database.