C12orf65

General Information

Gene Name       : C12orf65
Gene ID             : ENSG00000130921.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C12orf65)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C12orf65ENSG00000130921.717.5616.6717.12ENCSR000AEF
HepG2C12orf65ENSG00000130921.79.8010.189.99ENCSR985KAT
K562C12orf65ENSG00000130921.724.0424.9224.48ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C12orf65 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C12orf65 RNA is bound by 8 proteins.  







eCLIP assay for C12orf65 is not avaliable on ENCORE database.





8 proteins are bound to C12orf65 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12123738223123738423+3'-UTR,CDS3.083533.00343HepG2GRWD1
chr12123741498123741646+3'-UTR,CDS3.054656.36977K562ZNF800
chr12123742338123742458+3'-UTR5.739899.83131K562UPF1
chr12123741517123741641+3'-UTR,CDS4.214558.07592K562UCHL5
chr12123741554123741644+3'-UTR,CDS3.442173.95301K562ZNF622
chr12123742186123742229+3'-UTR3.643819.13328K562YBX3
chr12123738314123738428+3'-UTR,CDS4.252113.11168K562ZNF622
chr12123718000123718089+5'-UTR,intron-Proximal3.806117.37356K562DDX3X
chr12123738230123738301+CDS3.141533.29348K562YBX3
chr12123738605123738658+intron-Distal3.825375.60474K562RBM15
chr12123738913123738974+intron-Distal4.002193.73331K562RBM15
chr12123738756123738802+intron-Distal,intron-Proximal3.881683.15006K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C12orf65 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C12orf65 is not available on ENCORE database.

  • 32 RBPs can affect the levels of C12orf65.  








The Knockdown/knockout RNA-Seq assay for C12orf65 is not available on ENCORE database.





32 RBPs can affect the gene expression of C12orf65 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C12orf65ENSG00000130921.3190.55620260.09990-0.448802.155501.53600HepG2AUH
C12orf65ENSG00000130921.3116.61720184.83980-0.664502.626402.04130HepG2BOP1
C12orf65ENSG00000130921.3181.45090272.40270-0.586202.556601.95350HepG2DDX3X
C12orf65ENSG00000130921.3117.09220192.14930-0.714602.835901.90460HepG2EEF2
C12orf65ENSG00000130921.3158.31970224.95080-0.506801.794101.30450HepG2EIF2S1
C12orf65ENSG00000130921.3395.65680298.635400.405802.404701.83680HepG2ETF1
C12orf65ENSG00000130921.3159.30580232.67040-0.546502.158201.56780HepG2G3BP1
C12orf65ENSG00000130921.3128.40180252.28460-0.974405.130104.29550HepG2MATR3
C12orf65ENSG00000130921.3102.69340151.77840-0.563601.992501.46290HepG2RPS19
C12orf65ENSG00000130921.3251.99170181.717500.471601.936601.33960HepG2SF3B1
C12orf65ENSG00000130921.3120.21400202.19070-0.750102.557301.80680HepG2SNRNP70
C12orf65ENSG00000130921.3384.36270244.765100.651005.559204.88080HepG2SSB
C12orf65ENSG00000130921.3104.69640178.91380-0.773103.117602.35380HepG2TARDBP
C12orf65ENSG00000130921.377.31060120.08050-0.635302.232701.32830HepG2TFIP11
C12orf65ENSG00000130921.363.39770105.83230-0.739302.143601.47550HepG2UCHL5
C12orf65ENSG00000130921.3257.72850176.353500.547302.184901.53450HepG2XRN2
C12orf65ENSG00000130921.3469.32880719.01180-0.615407.213406.36020K562AGGF1
C12orf65ENSG00000130921.3497.05010748.16260-0.590004.021803.23230K562AKAP8L
C12orf65ENSG00000130921.31138.20140893.805500.348602.447501.88930K562AQR
C12orf65ENSG00000130921.3668.62850405.193700.722507.186005.86810K562EIF4A3
C12orf65ENSG00000130921.3480.64640660.17150-0.457903.023902.12770K562FMR1
C12orf65ENSG00000130921.3688.97970421.381900.709208.757107.75290K562FXR1
C12orf65ENSG00000130921.3466.95810725.41500-0.635502.661801.47340K562HNRNPA2B1
C12orf65ENSG00000130921.3805.69820568.539300.502903.430202.38480K562HNRNPM
C12orf65ENSG00000130921.3601.82490793.99350-0.399802.474101.69920K562KIF1C
C12orf65ENSG00000130921.3769.41870589.659300.383802.975302.10320K562MAGOH
C12orf65ENSG00000130921.31520.311901184.127400.360402.451401.68510K562PUF60
C12orf65ENSG00000130921.3321.69480741.98420-1.2057016.7267015.43210K562PUS1
C12orf65ENSG00000130921.3535.56590722.94180-0.432803.671903.00260K562RBM15
C12orf65ENSG00000130921.3728.70150561.644500.375602.714702.01350K562SRSF1
C12orf65ENSG00000130921.3730.15900490.130300.574905.890104.68300K562SYNCRIP
C12orf65ENSG00000130921.3437.83130568.39430-0.376502.199001.56400K562TARDBP
C12orf65ENSG00000130921.3814.57320680.611200.259102.228601.46220K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C12orf65 is not available on ENCORE database.





3 RBPs can affect the splicing of C12orf65 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC12orf65ENSG00000130921.3chr12+1237182861237184711237180081237180781237381931237385110.089000.000420.07731includedK562FTO
SEC12orf65ENSG00000130921.3chr12+1237182861237184711237180081237180781237381931237383540.070000.000300.00433includedK562AQR
SEC12orf65ENSG00000130921.3chr12+1237182861237184711237180081237180781237381931237385110.103000.000010.00039includedK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C12orf65 is not avaliable on ENCORE database.