HMGB2

General Information

Gene Name : HMGB2
Gene ID : ENSG00000164104.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HMGB2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HMGB2	ENSG00000164104.11	537.29	514.77	526.03	ENCSR000AEF
HepG2	HMGB2	ENSG00000164104.11	347.15	478.90	413.02	ENCSR985KAT
K562	HMGB2	ENSG00000164104.11	474.04	487.03	480.53	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HMGB2 is not avaliable on ENCORE database.

Proteins bound to RNA

HMGB2 RNA is bound by 59 proteins.

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eCLIP assay for HMGB2 is not avaliable on ENCORE database.

59 proteins are bound to HMGB2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	174253200	174253221	-	3'-UTR,intron-Distal	3.25175	400.00000	K562	BUD13
chr4	174253119	174253159	-	3'-UTR,intron-Distal	4.58581	400.00000	K562	UCHL5
chr4	174253180	174253201	-	3'-UTR,intron-Distal	5.13016	400.00000	K562	ZNF622
chr4	174253208	174253219	-	3'-UTR,intron-Distal	5.63271	400.00000	K562	ZNF622
chr4	174253202	174253223	-	3'-UTR,intron-Distal	5.96985	400.00000	K562	GRWD1
chr4	174253198	174253222	-	3'-UTR,intron-Distal	3.10697	400.00000	K562	DDX24
chr4	174253199	174253220	-	3'-UTR,intron-Distal	5.24076	400.00000	K562	SRSF1
chr4	174253208	174253221	-	3'-UTR,intron-Distal	6.42616	400.00000	K562	TARDBP
chr4	174253039	174253072	-	3'-UTR,intron-Distal	4.36446	400.00000	K562	PABPC4
chr4	174253129	174253198	-	3'-UTR,intron-Distal	3.03442	400.00000	K562	DDX24
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 320 entries

eCLIP assay for HMGB2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HMGB2 is not available on ENCORE database.
186 RBPs can affect the levels of HMGB2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HMGB2 is not available on ENCORE database.

186 RBPs can affect the gene expression of HMGB2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HMGB2	ENSG00000164104.7	118.80280	3569.75960	-4.90920	288.25840	284.48820	HepG2	BOP1
HMGB2	ENSG00000164104.7	769.55790	7122.94630	-3.21040	276.14000	272.63410	HepG2	RBM22
HMGB2	ENSG00000164104.7	621.89730	3858.97340	-2.63350	246.50980	242.83630	HepG2	TRIM56
HMGB2	ENSG00000164104.7	1639.41220	8045.18070	-2.29490	230.19310	227.54970	HepG2	SRFBP1
HMGB2	ENSG00000164104.7	1148.92230	4530.81870	-1.97950	206.11590	202.92970	HepG2	CKAP4
HMGB2	ENSG00000164104.7	356.84780	3385.12670	-3.24580	197.91350	194.24720	HepG2	RPS19
HMGB2	ENSG00000164104.7	548.84080	3824.73250	-2.80090	187.26600	184.33530	HepG2	TIAL1
HMGB2	ENSG00000164104.7	378.64630	3837.17600	-3.34110	174.08130	171.70000	HepG2	ZNF622
HMGB2	ENSG00000164104.7	2409.56800	8522.10630	-1.82240	163.24930	159.92250	HepG2	ETF1
HMGB2	ENSG00000164104.7	2313.28080	7715.53730	-1.73780	157.16000	154.34360	HepG2	PUM1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 235 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HMGB2 is not available on ENCORE database.

3 RBPs can affect the splicing of HMGB2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	HMGB2	ENSG00000164104.7	chr4	-	174254650	174254875			174254650	174254820	174255396	174255542	0.11800	0.00000	0.00000	longer	K562	AQR
A5SS	HMGB2	ENSG00000164104.7	chr4	-	174254219	174254297			174254268	174254297	174253971	174254146	-0.20600	0.00000	0.00000	shorter	K562	AQR
A5SS	HMGB2	ENSG00000164104.7	chr4	-	174254219	174254365			174254268	174254365	174253971	174254146	-0.07000	0.00000	0.00000	shorter	K562	SRSF1
RI	HMGB2	ENSG00000164104.7	chr4	-	174254099	174254297			174254099	174254146	174254219	174254297	0.07500	0.00000	0.00000	included	K562	AQR
MXE	HMGB2	ENSG00000164104.7	chr4	-	174254268	174254482	174254650	174254820	174253971	174254146	174255422	174256276	-0.15300	0.00000	0.00000	2included	K562	AQR
MXE	HMGB2	ENSG00000164104.7	chr4	-	174254268	174254365	174254650	174254820	174253971	174254146	174255422	174256276	-0.15500	0.00000	0.00000	2included	K562	AQR
A3SS	HMGB2	ENSG00000164104.7	chr4	-	174254650	174254790			174254650	174254737	174255422	174255583	-0.05900	0.00024	0.05878	shorter	HepG2	NCBP2
MXE	HMGB2	ENSG00000164104.7	chr4	-	174254268	174254365	174254650	174254737	174252851	174253389	174255422	174256276	-0.62900	0.00218	0.01792	2included	K562	AQR

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HMGB2

General Information

Functions

Localization

Domains (AlphaFold: HMGB2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HMGB2 is not avaliable on ENCORE database.

59 proteins are bound to HMGB2 RNA:

eCLIP assay for HMGB2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HMGB2 is not available on ENCORE database.

186 RBPs can affect the gene expression of HMGB2 :

The Knockdown/knockout RNA-Seq assay for HMGB2 is not available on ENCORE database.

3 RBPs can affect the splicing of HMGB2 :

The Knockdown/knockout RNA-Seq assay for HMGB2 is not avaliable on ENCORE database.