YWHAG

General Information

Gene Name : YWHAG
Gene ID : ENSG00000170027.6
Essential Gene : No

Functions

Novel RBP

Localization

Not Available

Domains (AlphaFold: YWHAG)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

GeneTex: GTX113298

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	YWHAG	ENSG00000170027.6	78.95	88.74	83.84	ENCSR000AEF
HepG2	YWHAG	ENSG00000170027.6	82.08	81.13	81.60	ENCSR985KAT
K562	YWHAG	ENSG00000170027.6	144.17	137.37	140.77	ENCSR000AEO

Assays

5 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 367	ENCSR867ZVK	YWHAG	K562	Released	ENCAB760OWH	ENCSR812PBU
knockdown followed by RNA-seq	YWHAG-BGHLV37-HepG2	ENCSR204QKA	YWHAG	HepG2	Released		ENCSR225PRV	shRNA	KD% = 55.5,55.8
knockdown followed by RNA-seq	YWHAG-BGKcLV08-K562	ENCSR163PNO	YWHAG	K562	Released		ENCSR015KGT	CRISPR	KD% = 63.0,67.5
knockdown followed by RNA-seq	YWHAG-BG293LV05-WT293		YWHAG	293T	Released			shRNA	KD% = ,
knockdown followed by RNA-seq	YWHAG-BG293LV06-WT293		YWHAG	293T	Released			shRNA	KD% = ,

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
YWHAG	367	K562	ENCSR867ZVK	ENCSR812PBU	ENCAB760OWH	GTX113298	40128	Released	ENCODE3

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
YWHAG	ENCAB760OWH	GTX113298	40128			Released, ENCODE3	BGHLV37-111, Released, ENCODE3	BGKcLV08-79, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
YWHAG	K562	shRNA			BGKLV36-45,BGKLV36-46	BGKLV36-1,BGKLV36-2	0.0,0.0	NotSatisfied	ENCODE3
YWHAG	K562	shRNA			BGKLV38-133,BGKLV38-134	BGKLV38-1,BGKLV38-2	0.0,16.1	NotSatisfied	ENCODE3
YWHAG	K562	shRNA			BGKLV38-135,BGKLV38-136	BGKLV38-1,BGKLV38-2	30.4,26.8	NotSatisfied	ENCODE3
YWHAG	K562	shRNA			BGKLV38-137,BGKLV38-138	BGKLV38-1,BGKLV38-2	19.4,27.2	NotSatisfied	ENCODE3
YWHAG	K562	shRNA			BGKLV38-139,BGKLV38-140	BGKLV38-1,BGKLV38-2	29.4,31.5	NotSatisfied	ENCODE3
YWHAG	HepG2	shRNA			BGHLV30-59,BGHLV30-60	BGHLV30-1,BGHLV30-2	43.6,37.3	NotSatisfied	ENCODE3
YWHAG	HepG2	shRNA			BGHLV35-55,BGHLV35-56	BGHLV35-1,BGHLV35-2	0.0,0.0	NotSatisfied	ENCODE3
YWHAG	HepG2	shRNA	ENCSR204QKA	ENCSR225PRV	YWHAG-BGHLV37-111C,YWHAG-BGHLV37-112C	non-target-BGHLV37-1C,non-target-BGHLV37-2C	55.5,55.8	Released	ENCODE4
YWHAG	HepG2	shRNA			BGHLV37-113,BGHLV37-114	BGHLV37-1,BGHLV37-2	29.0,37.7	NotSatisfied	ENCODE3
YWHAG	K562	CRISPR	ENCSR163PNO	ENCSR015KGT	YWHAG-BGKcLV08-79,YWHAG-BGKcLV08-80	NT-BGKcLV08-1,NT-BGKcLV08-2	63.0,67.5	Released	ENCODE4
YWHAG	K562	CRISPR			BGKcLV08-81,BGKcLV08-82	BGKcLV08-1,BGKcLV08-2	56.2,58.7	NotSatisfied	ENCODE4
YWHAG	293T	shRNA			BG293LV05-45,BG293LV05-46	BG293LV05-1,BG293LV05-2		NotSatisfied	ENCORE2
YWHAG	293T	shRNA			YWHAG-BG293LV05-47,YWHAG-BG293LV05-48	NT-BG293LV05-1,NT-BG293LV05-2	,	Released	ENCORE2
YWHAG	293T	shRNA			YWHAG-BG293LV06-75B,YWHAG-BG293LV06-76B	NT-BG293LV06-1B,NT-BG293LV06-2B	,	Released	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
YWHAG	Product_ID: GTX113298 Lot_ID: 40128 Source: GeneTex Target Name: YWHAG-human

RNA Targets

YWHAG protein binds to 774 RNA regions.

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Proteins bound to RNA

YWHAG RNA is bound by 36 proteins.

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YWHAG protein has 774 RNA targets:

Only display 100 entries as example. Please click "View All" button to see all 774 entries.

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RBP	Chr	Start	End	Strand	log2(fold change)	-log(p-value)	Cell Line	Matched Gene	Matched Area
YWHAG	chr17	41463624	41463684	-	4.69342	21.96583	K562	LINC00910	intron-Distal
YWHAG	chr1	2214802	2214956	+	6.45724	20.76035	K562	SKI	intron-Distal
YWHAG	chr1	2214249	2214336	+	5.00644	16.46182	K562	SKI	intron-Distal
YWHAG	chr16	89349933	89350050	-	4.53352	15.60996	K562	ANKRD11	3'-UTR,CDS,intron-Distal
YWHAG	chr17	41466363	41466402	-	4.39550	14.04446	K562	LINC00910	intron-Distal
YWHAG	chr1	2210807	2210938	+	5.81437	13.97475	K562	SKI	intron-Distal
YWHAG	chr18	75688707	75688796	-	3.69721	13.26723	K562	LINC01029	intron-Distal
YWHAG	chr8	94752785	94752843	-	5.58566	13.01450	K562	RBM12B	intron-Distal,intron-Proximal
YWHAG	chr7	23454611	23454692	-	4.24559	12.05870	K562	IGF2BP3	intron-Distal
YWHAG	chr8	94748456	94748502	-	4.21208	11.78233	K562	RBM12B	CDS,intron-Distal

Showing 1 to 10 of 100 entries

36 proteins are bound to YWHAG RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr7	75958454	75958529	-	3'-UTR,intron-Distal	4.43002	400.00000	K562	PUM2
chr7	75956911	75956987	-	3'-UTR,intron-Distal	5.84108	400.00000	K562	FAM120A
chr7	75957900	75958004	-	3'-UTR,intron-Distal	4.37680	400.00000	K562	FAM120A
chr7	75957996	75958028	-	3'-UTR,intron-Distal	4.85048	400.00000	K562	PABPC4
chr7	75956961	75956985	-	3'-UTR,intron-Distal	6.06458	400.00000	K562	UPF1
chr7	75956927	75956961	-	3'-UTR,intron-Distal	5.82893	400.00000	K562	UPF1
chr7	75958023	75958074	-	3'-UTR,intron-Distal	4.33906	400.00000	K562	UPF1
chr7	75958028	75958038	-	3'-UTR,intron-Distal	4.51008	400.00000	K562	PABPC4
chr7	75957719	75957769	-	3'-UTR,intron-Distal	4.41008	83.10004	K562	UPF1
chr7	75957670	75957719	-	3'-UTR,intron-Distal	4.29749	79.32773	K562	UPF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 143 entries

No autoregularoty interactions between protein YWHAG and its RNA.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for YWHAG is not available on ENCORE database.
100 RBPs can affect the levels of YWHAG.

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The Knockdown/knockout RNA-Seq assay for YWHAG is not available on ENCORE database.

100 RBPs can affect the gene expression of YWHAG :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
YWHAG	ENSG00000170027.5	11071.81560	6197.29460	0.83710	51.48140	50.03240	HepG2	SRFBP1
YWHAG	ENSG00000170027.5	1533.26180	3014.27140	-0.97520	45.97540	43.84700	HepG2	SAFB2
YWHAG	ENSG00000170027.5	5249.80660	8752.85540	-0.73750	38.83780	36.38490	K562	WDR43
YWHAG	ENSG00000170027.5	6250.45610	4103.35080	0.60710	24.26440	22.86660	HepG2	ACO1
YWHAG	ENSG00000170027.5	1595.24540	2500.97250	-0.64870	20.83100	19.30210	HepG2	ZC3H8
YWHAG	ENSG00000170027.5	7936.04180	5080.94560	0.64320	20.53060	19.10710	HepG2	CELF1
YWHAG	ENSG00000170027.5	5064.52100	3419.59120	0.56650	19.52360	18.30190	HepG2	SRSF9
YWHAG	ENSG00000170027.5	2553.61240	3925.80270	-0.62040	18.80690	17.40300	HepG2	DKC1
YWHAG	ENSG00000170027.5	3191.67080	5441.15600	-0.76960	17.62110	16.19610	K562	HNRNPC
YWHAG	ENSG00000170027.5	3710.24130	5380.71090	-0.53630	17.23250	16.18190	HepG2	SSB
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 116 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

YWHAG

General Information

Functions

Localization

Domains (AlphaFold: YWHAG)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

YWHAG protein has 774 RNA targets:

36 proteins are bound to YWHAG RNA:

No autoregularoty interactions between protein YWHAG and its RNA.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for YWHAG is not available on ENCORE database.

100 RBPs can affect the gene expression of YWHAG :

The Knockdown/knockout RNA-Seq assay for YWHAG is not available on ENCORE database.

No RBPs affect the alternative splcing events of YWHAG on ENCORE database.

The Knockdown/knockout RNA-Seq assay for YWHAG is not avaliable on ENCORE database.