TMED3

General Information

Gene Name       : TMED3
Gene ID             : ENSG00000166557.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMED3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMED3ENSG00000166557.1218.5231.2624.89ENCSR000AEF
HepG2TMED3ENSG00000166557.1280.0459.7569.90ENCSR985KAT
K562TMED3ENSG00000166557.1233.2229.0431.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMED3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMED3 RNA is bound by 14 proteins.  







eCLIP assay for TMED3 is not avaliable on ENCORE database.





14 proteins are bound to TMED3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157961455079614621+3'-UTR,CDS,intron-Distal3.998848.51824HepG2RPS3
chr157961479279614841+3'-UTR,intron-Distal3.214225.01814HepG2LARP4
chr157961501379615104+3'-UTR,intron-Distal4.163524.13758HepG2AKAP1
chr157961468179614728+3'-UTR,intron-Distal4.404045.07111HepG2UPF1
chr157961487779614951+3'-UTR,intron-Distal3.406954.14964K562UPF1
chr157961443179614485+3'-UTR,CDS,intron-Distal3.053983.50044K562YBX3
chr157961479679614879+3'-UTR,intron-Distal4.418395.31599HepG2AKAP1
chr157961431979614362+3'-UTR,CDS,intron-Distal,intron-Proximal3.749993.30795HepG2SND1
chr157961450379614676+3'-UTR,CDS,intron-Distal3.5130217.45749HepG2LARP4
chr157961505279615140+3'-UTR,intron-Distal4.830186.02674K562UPF1
chr157961501279615084+3'-UTR,intron-Distal4.397794.44583HepG2UPF1
chr157961477979614911+3'-UTR,intron-Distal4.5797717.63469HepG2UPF1
chr157961437179614429+3'-UTR,CDS,intron-Distal3.152154.64860HepG2SND1
chr157961457279614681+3'-UTR,intron-Distal5.6763413.02941HepG2UPF1
chr157961466279614745+3'-UTR,intron-Distal3.086183.91938K562UPF1
chr157960358079603681+5'-UTR,CDS4.145156.82597K562DDX3X
chr157960350479603567+5'-UTR4.206356.49041HepG2RPS3
chr157960358779603701+5'-UTR,CDS5.2853981.73859HepG2DDX3X
chr157960350879603587+5'-UTR6.8151348.78271HepG2DDX3X
chr157960623479606348+CDS,intron-Proximal4.4910510.76840K562SND1
chr157960625879606330+CDS3.521844.90834HepG2SND1
chr157960612279606171+CDS4.224913.92846K562SND1
chr157960360279603760+CDS,intron-Proximal3.289688.39246HepG2RPS3
chr157960369379603757+CDS3.773404.84058HepG2LIN28B
chr157960369879603760+CDS,intron-Proximal3.672955.12820K562LIN28B
chr157960610079606216+CDS3.422564.27261HepG2GRWD1
chr157960370779603751+CDS3.877439.23400HepG2DDX3X
chr157960896579609048+intron-Distal4.454635.58061HepG2SUGP2
chr157962675879626909+intron-Distal4.312664.15306K562SAFB2
chr157960968479609745+intron-Distal3.579154.87260HepG2HNRNPM
chr157962333779623485+intron-Distal4.266084.58306K562SAFB2
chr157960932279609445+intron-Distal4.6116311.31861HepG2HNRNPM
chr157960964179609720+intron-Distal4.174443.62238HepG2MATR3
chr157961314279613252+intron-Distal3.754575.63625HepG2HNRNPM
chr157960652579606634+intron-Distal4.441404.03269HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMED3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMED3 is not available on ENCORE database.

  • 109 RBPs can affect the levels of TMED3.  








The Knockdown/knockout RNA-Seq assay for TMED3 is not available on ENCORE database.





109 RBPs can affect the gene expression of TMED3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMED3ENSG00000166557.81077.239901261.19430-0.227502.074401.39680HepG2AKAP8L
TMED3ENSG00000166557.82015.046901743.577000.208702.185101.56210HepG2AUH
TMED3ENSG00000166557.81354.42560917.320600.562104.090103.01650HepG2BCLAF1
TMED3ENSG00000166557.8581.97510750.45710-0.366802.118501.58950HepG2BOP1
TMED3ENSG00000166557.81455.333801255.010500.213602.336601.71720HepG2CKAP4
TMED3ENSG00000166557.8790.563901214.29680-0.619202.834002.05910HepG2CNOT7
TMED3ENSG00000166557.81130.07950688.931400.713905.347504.42110HepG2CPSF6
TMED3ENSG00000166557.8492.63930652.00600-0.404402.959401.84880HepG2CSTF2
TMED3ENSG00000166557.8618.51140914.84090-0.564703.606001.96890HepG2CSTF2T
TMED3ENSG00000166557.82400.346901463.631000.7136018.9951017.61650HepG2CELF1
TMED3ENSG00000166557.82182.216301573.540800.4717012.1133010.73980HepG2DAZAP1
TMED3ENSG00000166557.8834.778801160.99290-0.475907.931506.64250HepG2DDX19B
TMED3ENSG00000166557.81069.18470870.413600.296602.499601.40320HepG2DDX1
TMED3ENSG00000166557.82749.031901986.368200.468704.271303.50840HepG2DDX3X
TMED3ENSG00000166557.81760.411501309.151900.427204.080002.52290HepG2DDX47
TMED3ENSG00000166557.8780.987101038.18430-0.410702.995102.19630HepG2DDX55
TMED3ENSG00000166557.8362.46350782.34180-1.110007.279605.73180HepG2DDX59
TMED3ENSG00000166557.81437.31230988.749400.539605.475604.10020HepG2DDX5
TMED3ENSG00000166557.82610.090001706.596900.612905.965905.08720HepG2DDX6
TMED3ENSG00000166557.81029.986301201.01950-0.221601.879701.30490HepG2DKC1
TMED3ENSG00000166557.81122.43310845.952900.407906.110505.19770HepG2DNAJC2
TMED3ENSG00000166557.82477.871901640.329400.595006.476405.59070HepG2EIF2S1
TMED3ENSG00000166557.8637.02630930.73830-0.547005.889504.39990HepG2EIF3G
TMED3ENSG00000166557.81343.582701812.62940-0.432003.092302.41770HepG2EIF4A3
TMED3ENSG00000166557.81231.557301765.09240-0.519303.415402.65360HepG2EIF4B
TMED3ENSG00000166557.81002.725901552.58580-0.6307011.7472010.25990HepG2EIF4G1
TMED3ENSG00000166557.8759.980201094.84760-0.526705.140403.69420HepG2ESF1
TMED3ENSG00000166557.8986.364302001.86030-1.0211034.5389032.84130HepG2ETF1
TMED3ENSG00000166557.81076.712401386.17570-0.364503.204102.36210HepG2FUBP3
TMED3ENSG00000166557.81282.90740953.046900.428702.344301.31220HepG2FUS
TMED3ENSG00000166557.81492.636801829.25280-0.293401.931001.34920HepG2FXR1
TMED3ENSG00000166557.81022.113101696.69730-0.731208.115507.00700HepG2G3BP1
TMED3ENSG00000166557.81252.710201801.52680-0.524205.102803.88100HepG2G3BP2
TMED3ENSG00000166557.8527.33580780.87780-0.566403.542402.82660HepG2GPKOW
TMED3ENSG00000166557.8958.066001198.46290-0.323003.730602.60860HepG2HDGF
TMED3ENSG00000166557.8634.49410861.66690-0.441503.277902.58230HepG2HNRNPA1
TMED3ENSG00000166557.82130.591201718.533500.310002.378401.72860HepG2HNRNPK
TMED3ENSG00000166557.82073.655901433.308000.5327014.6047013.16570HepG2HNRNPL
TMED3ENSG00000166557.8381.89240745.21330-0.964508.563507.52110HepG2HNRNPLL
TMED3ENSG00000166557.81356.619801724.58350-0.346202.424701.78750HepG2IGF2BP2
TMED3ENSG00000166557.8795.892201618.73800-1.024204.400203.16710HepG2IGF2BP3
TMED3ENSG00000166557.81689.743901107.206000.609804.449202.85790HepG2KRR1
TMED3ENSG00000166557.81059.759501840.07210-0.796009.068607.98040HepG2MATR3
TMED3ENSG00000166557.81459.173401032.752300.498605.279904.19010HepG2MSI2
TMED3ENSG00000166557.81940.060901110.192600.805204.797903.60400HepG2PABPC1
TMED3ENSG00000166557.81544.65500942.424500.7127015.8744014.13420HepG2PARN
TMED3ENSG00000166557.8896.370601729.30260-0.9480028.8282027.22080HepG2PCBP1
TMED3ENSG00000166557.81195.37660849.204500.493206.654205.54980HepG2PPIL4
TMED3ENSG00000166557.81416.093101759.59610-0.313303.845303.22350HepG2PTBP1
TMED3ENSG00000166557.82317.645101581.278800.5515017.1356015.92010HepG2PUM1
TMED3ENSG00000166557.8993.347301278.65430-0.364304.981604.19880HepG2PUS1
TMED3ENSG00000166557.81192.340601905.75850-0.6766012.9669011.75910HepG2QKI
TMED3ENSG00000166557.81193.93950870.450700.455801.951201.34920HepG2RAVER1
TMED3ENSG00000166557.8858.164301673.18470-0.9633024.0442022.81730HepG2RBM22
TMED3ENSG00000166557.81368.244901729.57090-0.338103.222002.50030HepG2RBM25
TMED3ENSG00000166557.81158.383501958.28970-0.7575019.4926018.31120HepG2NELFE
TMED3ENSG00000166557.81078.409701823.82950-0.7581019.5019018.11800HepG2RECQL
TMED3ENSG00000166557.8841.356901476.45710-0.8113012.2431010.98690HepG2RPLP0
TMED3ENSG00000166557.8513.52840807.05250-0.652207.007606.08010HepG2RPS19
TMED3ENSG00000166557.8830.013101220.33510-0.556102.219101.50260HepG2RPS3A
TMED3ENSG00000166557.81023.42240847.894600.271302.696502.05810HepG2SAFB2
TMED3ENSG00000166557.81828.476401168.649300.645702.986502.28510HepG2SF3A3
TMED3ENSG00000166557.81285.208501832.02760-0.511409.746108.73600HepG2SF3B4
TMED3ENSG00000166557.81694.362501428.379300.246303.508102.73390HepG2SLBP
TMED3ENSG00000166557.81319.45160988.788700.416106.931805.98430HepG2SMN1
TMED3ENSG00000166557.81616.13260888.306100.863308.491706.76760HepG2SMNDC1
TMED3ENSG00000166557.81287.83940820.690200.649902.107901.42860HepG2SNRNP70
TMED3ENSG00000166557.81131.125301889.80030-0.7405020.6425019.60490HepG2SRFBP1
TMED3ENSG00000166557.81201.668901912.21530-0.6702016.6081015.65610HepG2SRSF1
TMED3ENSG00000166557.81161.972201640.79370-0.497809.274008.44230HepG2SSB
TMED3ENSG00000166557.81209.264901672.61360-0.468008.451607.46390HepG2SUCLG1
TMED3ENSG00000166557.81309.83510861.644600.604107.206505.74090HepG2SUPT6H
TMED3ENSG00000166557.8713.135101033.39250-0.535104.201803.39210HepG2SUPV3L1
TMED3ENSG00000166557.8953.747401718.70460-0.8496019.7235018.42150HepG2TAF15
TMED3ENSG00000166557.81367.19930726.563300.912005.308404.34970HepG2TARDBP
TMED3ENSG00000166557.8618.572701084.60110-0.810104.115302.83210HepG2TBRG4
TMED3ENSG00000166557.81093.27120933.421200.228002.020501.52420HepG2TRIM56
TMED3ENSG00000166557.81725.477901455.329800.245502.084601.33560HepG2TUFM
TMED3ENSG00000166557.81502.650401091.708800.460803.869003.13080HepG2U2AF1
TMED3ENSG00000166557.81169.045901540.52090-0.398102.412701.63520HepG2UBE2L3
TMED3ENSG00000166557.81276.838901036.413500.300903.441002.67560HepG2UPF1
TMED3ENSG00000166557.8832.338101017.26470-0.289502.039701.40960HepG2XRN2
TMED3ENSG00000166557.8491.57400833.68220-0.7621013.5627012.26240HepG2ZC3H8
TMED3ENSG00000166557.81821.805401139.856100.6764020.3509019.20500HepG2ZNF622
TMED3ENSG00000166557.81088.73670875.129600.315003.075301.48010K562AKAP1
TMED3ENSG00000166557.81843.082101277.446400.528803.753102.57030K562AKAP8
TMED3ENSG00000166557.82130.437101209.580200.8165014.9030013.17990K562AKAP8L
TMED3ENSG00000166557.81786.099701269.198200.492806.224904.78680K562ATP5C1
TMED3ENSG00000166557.8549.84920417.353800.397702.590201.83030K562CPSF6
TMED3ENSG00000166557.81182.87100886.695600.415704.016202.73110K562DDX3X
TMED3ENSG00000166557.81165.59420898.980500.374604.015602.34950K562DDX6
TMED3ENSG00000166557.8830.24740621.059500.418702.221601.30440K562EIF3D
TMED3ENSG00000166557.8771.74070529.724000.542804.678703.55420K562FIP1L1
TMED3ENSG00000166557.8481.27850672.42770-0.482503.150901.93170K562FKBP4
TMED3ENSG00000166557.8665.26140963.37180-0.534206.812105.92300K562FXR1
TMED3ENSG00000166557.8335.07550604.26500-0.850703.738002.88820K562G3BP2
TMED3ENSG00000166557.8528.21070398.470500.406502.384201.64450K562GPKOW
TMED3ENSG00000166557.81790.775201195.339700.583107.761806.48290K562GRSF1
TMED3ENSG00000166557.81310.65060804.434100.704103.058801.75910K562HNRNPA2B1
TMED3ENSG00000166557.8397.16180774.23020-0.9630012.9032011.69050K562HNRNPC
TMED3ENSG00000166557.8485.40450691.46130-0.510504.136002.70820K562HNRNPF
TMED3ENSG00000166557.8678.02400435.718700.637804.812603.54840K562HNRNPM
TMED3ENSG00000166557.8955.16170718.174800.411303.033002.20070K562HSPD1
TMED3ENSG00000166557.81139.10630758.908500.585802.675501.67150K562IGF2BP2
TMED3ENSG00000166557.81801.195601283.560500.488706.161104.82050K562KIF1C
TMED3ENSG00000166557.81668.301801228.769600.441104.152402.75360K562MAK16
TMED3ENSG00000166557.8575.28260795.59040-0.467804.201603.04560K562MATR3
TMED3ENSG00000166557.81574.198501007.891900.643205.495804.10110K562NAA15
TMED3ENSG00000166557.81501.06390703.490401.093306.882105.10440K562PABPN1
TMED3ENSG00000166557.8944.07510601.360600.650606.795605.40940K562PPIG
TMED3ENSG00000166557.81555.56140836.213100.895404.516402.48260K562PPP1R8
TMED3ENSG00000166557.82193.825801199.354600.8711014.7390013.52550K562PUS1
TMED3ENSG00000166557.81810.944701168.770300.631707.913106.94160K562RBM15
TMED3ENSG00000166557.81452.88910643.266801.175305.717603.78410K562SF1
TMED3ENSG00000166557.81301.46850784.078000.731003.011201.62510K562SFPQ
TMED3ENSG00000166557.8933.28570717.298300.379602.766701.71810K562SRSF5
TMED3ENSG00000166557.81554.71350883.737300.814902.828801.38240K562SUPT6H
TMED3ENSG00000166557.81072.73680768.496000.481102.783102.07460K562TARDBP
TMED3ENSG00000166557.8918.08910741.321900.308402.256701.52450K562TIA1
TMED3ENSG00000166557.81183.55330934.876300.340202.992402.24510K562UPF1
TMED3ENSG00000166557.81777.270301216.240100.547102.723501.44520K562UTP18
TMED3ENSG00000166557.81304.45160751.805300.794903.588301.59030K562XPO5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMED3 is not available on ENCORE database.





4 RBPs can affect the splicing of TMED3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMED3ENSG00000166557.8chr15+7960688279606997796060987960634779614319796151790.101000.000000.00004includedK562AQR
SETMED3ENSG00000166557.8chr15+7960688279606997796060987960634779614319796151790.072000.000710.05544includedK562SUPV3L1
SETMED3ENSG00000166557.8chr15+796068827960704179606098796063477961431979615179-0.061000.002610.09036excludedHepG2SFPQ
SETMED3ENSG00000166557.8chr15+7960688279606997796060987960634779614319796151790.112000.000030.00085includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMED3 is not avaliable on ENCORE database.