DDC

General Information

Gene Name       : DDC
Gene ID             : ENSG00000132437.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DDC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DDCENSG00000132437.170.000.000.00ENCSR000AEF
HepG2DDCENSG00000132437.1734.0246.5440.28ENCSR985KAT
K562DDCENSG00000132437.170.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DDC is not avaliable on ENCORE database.



Proteins bound to RNA
  • DDC RNA is bound by 5 proteins.  







eCLIP assay for DDC is not avaliable on ENCORE database.





5 proteins are bound to DDC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr75054744250547538-3'-UTR,CDS,intron-Distal,intron-Proximal3.516995.95351HepG2PRPF8
chr75059698750597041-CDS,intron-Distal,intron-Proximal4.424747.72847HepG2PPIG
chr75060553450605582-CDS,intron-Distal,intron-Proximal4.111843.45943HepG2BCLAF1
chr75060555750605595-CDS,intron-Distal,intron-Proximal4.192756.39364HepG2PPIG
chr75056682050566862-CDS,intron-Distal,intron-Proximal4.580484.02817HepG2PRPF8
chr75059579950595839-CDS,intron-Distal,intron-Proximal3.782437.09156HepG2PRPF8
chr75058960750589677-intron-Distal4.270763.51329HepG2MATR3
chr75056694650566995-intron-Distal,intron-Proximal3.578505.09328HepG2SF3B4
chr75058270150582807-intron-Distal4.614795.01910HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DDC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DDC is not available on ENCORE database.

  • 136 RBPs can affect the levels of DDC.  








The Knockdown/knockout RNA-Seq assay for DDC is not available on ENCORE database.





136 RBPs can affect the gene expression of DDC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DDCENSG00000132437.13181.47370497.57690-1.4552018.7784016.40360HepG2AATF
DDCENSG00000132437.131268.32900668.218800.9244011.232509.54390HepG2ABCF1
DDCENSG00000132437.1384.27980498.18200-2.5634040.6329038.97520HepG2ACO1
DDCENSG00000132437.13487.48390332.668400.551203.668402.54000HepG2ADAR
DDCENSG00000132437.1369.221001460.91850-4.39950132.04310129.42490HepG2AKAP1
DDCENSG00000132437.13118.81550309.27170-1.380209.248507.47340HepG2AKAP8
DDCENSG00000132437.13329.5192097.146101.762006.443103.68810HepG2APOBEC3C
DDCENSG00000132437.13808.767501208.78770-0.579805.238804.17470HepG2ASCC1
DDCENSG00000132437.13505.86640817.59750-0.6926010.078808.90510HepG2AUH
DDCENSG00000132437.13335.02800505.68760-0.594002.984602.18550HepG2CALR
DDCENSG00000132437.131519.156801148.431400.403503.189802.36140HepG2CIRBP
DDCENSG00000132437.13399.13940497.96860-0.319202.266701.65590HepG2CKAP4
DDCENSG00000132437.13271.41800550.28370-1.0197011.792609.70710HepG2CPSF7
DDCENSG00000132437.13557.26380341.154600.707807.646505.97280HepG2YBX3
DDCENSG00000132437.13534.94690338.014100.662204.787503.42300HepG2CSTF2
DDCENSG00000132437.13145.52320586.07360-2.0098043.7489041.82650HepG2CELF1
DDCENSG00000132437.13816.46360460.698600.8255016.4906014.84700HepG2DDX19B
DDCENSG00000132437.13497.40020341.616500.541904.462403.00950HepG2DDX1
DDCENSG00000132437.131245.18100548.755601.1820022.2875020.61330HepG2DDX21
DDCENSG00000132437.13871.48900537.184100.698008.358506.78640HepG2DDX24
DDCENSG00000132437.13755.49000503.501100.585302.977101.64260HepG2DDX27
DDCENSG00000132437.13149.57130538.21140-1.8473023.4701021.55860HepG2DDX55
DDCENSG00000132437.131040.40630565.782400.8787011.376309.49360HepG2DDX5
DDCENSG00000132437.1353.286501202.15500-4.49570122.04540118.99110HepG2DDX6
DDCENSG00000132437.13728.79390323.083501.1735017.6542015.54910HepG2DHX30
DDCENSG00000132437.131029.75180476.598001.1114026.0326024.48040HepG2DKC1
DDCENSG00000132437.13970.55950487.646200.9929012.2243010.48530HepG2EEF2
DDCENSG00000132437.13351.40150505.47930-0.524502.739201.63920HepG2AGO1
DDCENSG00000132437.13332.214501155.66220-1.7985035.6414033.67300HepG2EIF2S1
DDCENSG00000132437.13108.22900395.84260-1.8708021.4328019.19350HepG2EIF3D
DDCENSG00000132437.13917.46350518.334200.8237011.792209.88440HepG2EIF3G
DDCENSG00000132437.13536.486401243.47690-1.2128013.6494012.18800HepG2EIF4B
DDCENSG00000132437.13994.39500621.719500.6775010.481909.05320HepG2EIF4G1
DDCENSG00000132437.13849.51700595.586100.512203.894702.93840HepG2EIF4G2
DDCENSG00000132437.13955.47950578.840500.723007.791506.08810HepG2ESF1
DDCENSG00000132437.13208.65370353.81950-0.761906.227304.43870HepG2FAM120A
DDCENSG00000132437.13355.15470523.04150-0.558504.245202.87290HepG2FASTKD2
DDCENSG00000132437.13102.13400674.73840-2.7239047.2822044.89960HepG2FIP1L1
DDCENSG00000132437.13810.72160447.939900.855807.335805.41100HepG2FKBP4
DDCENSG00000132437.131087.72480394.851801.461809.383507.54430HepG2FTO
DDCENSG00000132437.13388.98980855.79180-1.1375018.0043016.08680HepG2FUBP3
DDCENSG00000132437.13628.103401288.58200-1.0367014.8481013.37880HepG2FXR1
DDCENSG00000132437.13527.170001195.34980-1.1811017.0305015.44900HepG2G3BP1
DDCENSG00000132437.13591.46070352.441500.746806.323804.97310HepG2GEMIN5
DDCENSG00000132437.13404.47670528.09150-0.384702.301901.37690HepG2GNB2L1
DDCENSG00000132437.131474.52500446.691001.7228028.8584027.05320HepG2GPKOW
DDCENSG00000132437.13210.59510562.18380-1.4166013.0116010.09200HepG2GTF2F1
DDCENSG00000132437.13338.46350475.55740-0.490604.257003.06400HepG2HDGF
DDCENSG00000132437.13352.21800571.94980-0.699403.425001.86490HepG2HLTF
DDCENSG00000132437.13755.42800338.177801.1594016.5726015.20550HepG2HNRNPA1
DDCENSG00000132437.13381.45690579.19970-0.602506.468705.14210HepG2HNRNPA2B1
DDCENSG00000132437.1336.4534085.79600-1.234903.030401.55960HepG2HNRNPAB
DDCENSG00000132437.13548.83980376.169800.544903.772102.97240HepG2HNRNPC
DDCENSG00000132437.13531.59250360.583400.559905.303004.34990HepG2HNRNPF
DDCENSG00000132437.13303.307201210.39740-1.9966047.9724045.40170HepG2HNRNPK
DDCENSG00000132437.13331.42780574.18580-0.7928011.5033010.21200HepG2HNRNPL
DDCENSG00000132437.131035.71080426.292201.2806014.2180012.94370HepG2HNRNPLL
DDCENSG00000132437.13244.53530465.53460-0.928809.320207.75170HepG2HNRNPM
DDCENSG00000132437.13484.28310336.619000.524602.574801.39300HepG2HSPD1
DDCENSG00000132437.13726.35310355.070301.0325015.6339014.06220HepG2IGF2BP1
DDCENSG00000132437.13910.573201215.04740-0.416202.888402.20130HepG2IGF2BP2
DDCENSG00000132437.13212.542801140.26790-2.4235019.4685017.12440HepG2IGF2BP3
DDCENSG00000132437.13270.15990381.70230-0.498604.067803.19600HepG2ILF2
DDCENSG00000132437.13549.93410336.414700.708904.202102.65160HepG2KRR1
DDCENSG00000132437.13232.64240517.49870-1.1534014.1633011.80240HepG2LARP7
DDCENSG00000132437.13935.039101296.24670-0.471203.312402.62790HepG2MATR3
DDCENSG00000132437.1387.00180414.27260-2.2515018.4500015.94430HepG2METAP2
DDCENSG00000132437.13348.49490546.07960-0.648005.443404.34170HepG2MSI2
DDCENSG00000132437.13299.30880458.54740-0.615404.549002.99130HepG2NAA15
DDCENSG00000132437.13691.547401326.78090-0.9400011.8200010.55270HepG2NCBP2
DDCENSG00000132437.13284.51490624.99130-1.1353016.8943015.10310HepG2NOL12
DDCENSG00000132437.13879.37670378.043601.2178017.7365016.04150HepG2NSUN2
DDCENSG00000132437.13330.14600525.82340-0.671505.153702.40070HepG2NUSAP1
DDCENSG00000132437.1313.9977095.05700-2.763606.722505.29690HepG2PABPC1
DDCENSG00000132437.13454.453901181.58620-1.3785023.0040020.97830HepG2PABPC4
DDCENSG00000132437.13184.24870369.86930-1.0054010.595409.11580HepG2PARN
DDCENSG00000132437.13803.819701208.43340-0.588206.412805.54840HepG2PCBP1
DDCENSG00000132437.13230.19330564.56690-1.2943011.808409.88540HepG2PCBP2
DDCENSG00000132437.1321.5335093.27820-2.115005.396603.29990HepG2PNPT1
DDCENSG00000132437.13569.76170327.019200.800903.302001.38230HepG2PPIG
DDCENSG00000132437.13930.10530552.673400.7509012.8244011.33960HepG2PRPF4
DDCENSG00000132437.131109.76460593.475800.902907.377405.47990HepG2PRPF6
DDCENSG00000132437.13519.380901229.54720-1.2433021.6096020.36040HepG2PTBP1
DDCENSG00000132437.131947.72550596.575501.7069020.0509018.64080HepG2PUF60
DDCENSG00000132437.13893.21130507.415300.8157015.6850014.42820HepG2PUS1
DDCENSG00000132437.13892.970101331.79820-0.576704.401803.63990HepG2QKI
DDCENSG00000132437.1349.50910544.74380-3.4598041.3117038.94880HepG2RAVER1
DDCENSG00000132437.13173.10140631.32030-1.8668037.3310034.88150HepG2RBM15
DDCENSG00000132437.13322.60080784.57820-1.2822024.7836023.54230HepG2RBM22
DDCENSG00000132437.13399.107701208.62890-1.5985028.7278026.72980HepG2RBM25
DDCENSG00000132437.13406.96710624.04130-0.616705.137203.76840HepG2RBM27
DDCENSG00000132437.13761.254601368.43360-0.846108.864707.99700HepG2NELFE
DDCENSG00000132437.13835.530001274.39100-0.609008.255707.27610HepG2RECQL
DDCENSG00000132437.13587.17060388.456600.595904.438103.60300HepG2RPLP0
DDCENSG00000132437.13743.34080535.243900.473702.306901.44290HepG2RPS10
DDCENSG00000132437.13608.38720104.346302.5435037.4045034.65870HepG2RPS3A
DDCENSG00000132437.13375.04470587.49490-0.647505.496303.96640HepG2RPS5
DDCENSG00000132437.13102.89260410.50990-1.9963023.2153021.36320HepG2RRP9
DDCENSG00000132437.13649.09590332.774800.9638016.6008015.21860HepG2SAFB2
DDCENSG00000132437.13237.1326099.202101.257203.226501.54890HepG2SBDS
DDCENSG00000132437.13672.990001125.60710-0.742006.248405.20960HepG2SF3A3
DDCENSG00000132437.13602.84280421.902100.514802.370601.71500HepG2SF3B1
DDCENSG00000132437.13473.767501280.25890-1.4342025.6719024.18120HepG2SF3B4
DDCENSG00000132437.13262.88450554.31680-1.076302.988201.46780HepG2SFPQ
DDCENSG00000132437.13836.89210571.942500.549107.350706.29130HepG2SLBP
DDCENSG00000132437.13201.32300388.06220-0.9468010.967709.82150HepG2SMN1
DDCENSG00000132437.13160.30660555.84230-1.7938021.9259019.24850HepG2SMNDC1
DDCENSG00000132437.13344.50860530.50510-0.622803.648201.79300HepG2SND1
DDCENSG00000132437.13271.91930469.45550-0.787801.978501.32280HepG2SNRNP70
DDCENSG00000132437.13125.35280886.15850-2.82160100.4465098.52920HepG2SRFBP1
DDCENSG00000132437.131778.810001336.255300.412603.142502.64670HepG2SRSF1
DDCENSG00000132437.13418.52580588.98440-0.492902.872202.23440HepG2SRSF5
DDCENSG00000132437.13661.49300354.265900.9008013.9651012.61050HepG2SRSF7
DDCENSG00000132437.13185.985401087.06520-2.5472052.6134050.80480HepG2SRSF9
DDCENSG00000132437.132586.05260769.406501.7488076.4665074.72330HepG2SSB
DDCENSG00000132437.1347.1604090.72360-0.943902.326701.33230HepG2STIP1
DDCENSG00000132437.13220.48890509.09690-1.207209.003606.91950HepG2SUB1
DDCENSG00000132437.13538.64160669.87780-0.314602.862102.23190HepG2SUCLG1
DDCENSG00000132437.13274.62000455.60760-0.730405.757104.42620HepG2SUPT6H
DDCENSG00000132437.13772.67690535.729000.528302.868602.18120HepG2SUPV3L1
DDCENSG00000132437.13740.085901200.91820-0.6984010.395809.41910HepG2TAF15
DDCENSG00000132437.13768.41590415.700300.886205.946504.94160HepG2TARDBP
DDCENSG00000132437.131344.69200329.561102.0286019.7506017.31180HepG2TBRG4
DDCENSG00000132437.13231.10640359.04860-0.635604.218603.02330HepG2TFIP11
DDCENSG00000132437.13456.383001103.65020-1.2740021.5530019.31100HepG2TIA1
DDCENSG00000132437.131146.42740363.066101.6587046.7040045.11360HepG2TIAL1
DDCENSG00000132437.13230.50640366.35020-0.668405.769705.00900HepG2TRIM56
DDCENSG00000132437.13208.47260594.44510-1.511705.699704.23680HepG2U2AF2
DDCENSG00000132437.13361.63800616.80550-0.770303.453202.51560HepG2UBE2L3
DDCENSG00000132437.13114.96480316.43600-1.4607014.1836012.49820HepG2UCHL5
DDCENSG00000132437.131882.08670998.238800.9148030.5012028.69780HepG2UPF1
DDCENSG00000132437.13128.95760535.80730-2.0548022.5301019.42390HepG2XRCC5
DDCENSG00000132437.13285.00720599.14850-1.071909.033307.23750HepG2XRCC6
DDCENSG00000132437.131095.42670527.368001.0545012.6126011.08810HepG2XRN2
DDCENSG00000132437.13962.49020545.418100.8193017.0172015.59350HepG2ZC3H8
DDCENSG00000132437.13572.521101097.87530-0.9393025.5347024.29610HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DDC is not available on ENCORE database.





5 RBPs can affect the splicing of DDC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDDCENSG00000132437.13chr7-5060761250607726506055575060567750611582506118110.331000.000000.00055includedHepG2QKI
SEDDCENSG00000132437.13chr7-5060761250607726506055575060567750611582506118110.318000.000060.01047includedHepG2SRSF7
SEDDCENSG00000132437.13chr7-5060761250607726506055575060567750611582506118110.281000.001130.05672includedHepG2PTBP1
SEDDCENSG00000132437.13chr7-5060761250607726506055575060567750611582506117950.283000.000650.06624includedHepG2LARP4
SEDDCENSG00000132437.13chr7-5060761250607726506055575060567750611582506118170.456000.000000.00049includedHepG2TIAL1
MXEDDCENSG00000132437.13chr7-50595834505959785060555750605677505716905057175750607612506077260.284000.003230.068961includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DDC is not avaliable on ENCORE database.