VRK3

General Information

Gene Name       : VRK3
Gene ID             : ENSG00000105053.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: VRK3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VRK3ENSG00000105053.1038.8242.1540.48ENCSR000AEF
HepG2VRK3ENSG00000105053.1019.7227.0923.41ENCSR985KAT
K562VRK3ENSG00000105053.1057.3963.4560.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VRK3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VRK3 RNA is bound by 7 proteins.  







eCLIP assay for VRK3 is not avaliable on ENCORE database.





7 proteins are bound to VRK3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195049611150496164-3'-UTR,CDS,intron-Distal,intron-Proximal4.742724.38106HepG2PPIG
chr195049852150498532-3'-UTR,CDS,intron-Distal3.384067.38488K562YBX3
chr195049288350492897-3'-UTR,CDS,intron-Distal,intron-Proximal5.9898512.46873K562AQR
chr195051077750510850-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.847415.01842HepG2PRPF8
chr195051098150511026-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.480564.08171K562YBX3
chr195049173250491833-3'-UTR,CDS,intron-Distal,intron-Proximal3.876004.57180HepG2AQR
chr195049282650492914-3'-UTR,CDS,intron-Distal,intron-Proximal4.487558.96422HepG2PRPF8
chr195048497350485077-3'-UTR,intron-Distal4.497115.44904K562TARDBP
chr195051081550511026-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.593116.39464HepG2BCLAF1
chr195049848950498521-3'-UTR,CDS,intron-Distal3.8316610.52461K562YBX3
chr195048499250485056-3'-UTR,intron-Distal5.2909519.16083K562EIF4G2
chr195051928050519310-5'-UTR,CDS,intron-Distal,intron-Proximal3.369374.31744K562YBX3
chr195051249250512616-5'-UTR,CDS,intron-Distal,intron-Proximal3.437703.59112HepG2PPIG
chr195052384150523892-5'-UTR,intron-Distal,intron-Proximal3.543578.00668K562YBX3
chr195049280950492883-intron-Distal,intron-Proximal6.4586618.17544K562AQR
chr195049180650491879-intron-Distal,intron-Proximal3.805933.34609K562TARDBP
chr195049187950491969-intron-Distal4.023983.46495K562TARDBP
chr195050396650504045-intron-Distal,intron-Proximal3.199704.76426K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VRK3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VRK3 is not available on ENCORE database.

  • 36 RBPs can affect the levels of VRK3.  








The Knockdown/knockout RNA-Seq assay for VRK3 is not available on ENCORE database.





36 RBPs can affect the gene expression of VRK3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VRK3ENSG00000105053.6623.52660481.305200.373403.299502.64530HepG2ACO1
VRK3ENSG00000105053.61017.89170646.281900.655205.172004.47360HepG2AKAP1
VRK3ENSG00000105053.6318.69920483.48060-0.601305.754004.68410HepG2AKAP8L
VRK3ENSG00000105053.6495.86030681.67620-0.459204.541803.70010HepG2AUH
VRK3ENSG00000105053.6784.98240380.151001.0460014.2127013.00480HepG2BOP1
VRK3ENSG00000105053.6810.92600508.050700.674506.091204.97360HepG2CIRBP
VRK3ENSG00000105053.6631.81180422.433600.580702.828902.05490HepG2CNOT7
VRK3ENSG00000105053.6482.88360365.761000.400702.231601.61530HepG2DDX21
VRK3ENSG00000105053.6361.87350550.08780-0.604203.144202.41390HepG2EIF4B
VRK3ENSG00000105053.6407.66420653.25420-0.680307.616106.35430HepG2EIF4G1
VRK3ENSG00000105053.6216.95260329.73640-0.603903.395301.99690HepG2FKBP4
VRK3ENSG00000105053.6750.99080537.543700.482303.304302.57230HepG2IGF2BP2
VRK3ENSG00000105053.6493.02000728.04580-0.562403.569902.62560HepG2LARP4
VRK3ENSG00000105053.6832.59720654.151200.347903.001402.46790HepG2RBM22
VRK3ENSG00000105053.6363.70420506.42050-0.477602.634001.66650HepG2RBM27
VRK3ENSG00000105053.6804.87050579.125800.474803.826003.04290HepG2RPLP0
VRK3ENSG00000105053.6176.85380302.17340-0.772804.388803.42400HepG2RRP9
VRK3ENSG00000105053.6467.09500589.64430-0.336102.392901.83760HepG2SF3B4
VRK3ENSG00000105053.6559.77960409.651000.450402.247201.39300HepG2SMNDC1
VRK3ENSG00000105053.6507.49630703.74440-0.471704.767303.98970HepG2SUCLG1
VRK3ENSG00000105053.6549.70500396.010600.473003.154702.15740HepG2SUPT6H
VRK3ENSG00000105053.6396.47330553.18810-0.480503.830703.18900HepG2TAF15
VRK3ENSG00000105053.61034.13180504.900401.0342028.6074027.32180HepG2ZNF622
VRK3ENSG00000105053.61188.844401451.77170-0.288301.824301.32840K562AQR
VRK3ENSG00000105053.61014.34440751.649900.432303.136902.20660K562BOP1
VRK3ENSG00000105053.6487.59390776.04550-0.670506.540605.09090K562EFTUD2
VRK3ENSG00000105053.61206.541201004.229300.264702.399001.72110K562EIF2S2
VRK3ENSG00000105053.61191.46910878.135400.440103.829502.82060K562FIP1L1
VRK3ENSG00000105053.6397.74910651.23440-0.711304.961703.95020K562G3BP2
VRK3ENSG00000105053.6951.65650722.279300.397802.473201.59560K562HNRNPM
VRK3ENSG00000105053.6791.048501253.61820-0.6643011.047709.29240K562HNRNPU
VRK3ENSG00000105053.61300.177201579.95120-0.281202.214001.41620K562MBNL1
VRK3ENSG00000105053.6968.19360744.792900.378403.040102.12030K562METAP2
VRK3ENSG00000105053.61346.63150996.858000.433803.787502.80590K562PPIG
VRK3ENSG00000105053.6411.65060755.18540-0.875409.387408.00200K562PRPF8
VRK3ENSG00000105053.6464.50110772.03040-0.733005.392603.53730K562RRP9
VRK3ENSG00000105053.6523.46780677.18920-0.371502.865601.99490K562SF3B4
VRK3ENSG00000105053.6447.43330631.28020-0.496603.029101.87360K562U2AF1
VRK3ENSG00000105053.6354.69170651.96770-0.8782011.351109.71060K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VRK3 is not available on ENCORE database.





18 RBPs can affect the splicing of VRK3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEVRK3ENSG00000105053.6chr19-5048011950480268504797485048004150482339504824990.052000.005210.07642includedK562SF3B4
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.218000.000000.00019excludedK562PRPF8
SEVRK3ENSG00000105053.6chr19-505007605050082750498447504985325050404650504111-0.245000.003980.06325excludedHepG2U2AF1
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.155000.002120.04914excludedHepG2HNRNPK
SEVRK3ENSG00000105053.6chr19-505007605050082750498447504985325050404650504111-0.160000.000090.00156excludedK562AQR
SEVRK3ENSG00000105053.6chr19-504980705049817650496116504962095049844750498532-0.062000.003960.03848excludedK562AQR
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.115000.002600.08048excludedK562FXR1
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.127000.000490.04278excludedK562SUPV3L1
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.196000.000010.00090excludedK562EFTUD2
SEVRK3ENSG00000105053.6chr19-505007605050082750498447504985325050404650504111-0.190000.001420.06602excludedK562EFTUD2
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.117000.002910.06998excludedHepG2SF3A3
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.118000.000070.01623excludedK562SRSF7
SEVRK3ENSG00000105053.6chr19-505007605050082750498447504985325050404650504111-0.140000.000120.00696excludedK562HNRNPU
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.071000.003710.07283excludedK562RBM15
SEVRK3ENSG00000105053.6chr19-5051249250512642505108255051108350519280505194200.093000.000480.06877includedK562ZC3H8
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.157000.000120.00879excludedK562HNRNPK
SEVRK3ENSG00000105053.6chr19-505124925051254650510825505110835051928050519420-0.255000.000300.06375excludedK562SAFB
SEVRK3ENSG00000105053.6chr19-505124925051264250510825505110835051928050519420-0.166000.000020.00166excludedK562PTBP1
SEVRK3ENSG00000105053.6chr19-505007605050082750498447504985325050404650504111-0.290000.000000.00000excludedK562HNRNPC
A3SSVRK3ENSG00000105053.6chr19-5051938850519461505193885051942050523841505239040.069000.000000.00000longerK562AQR
A3SSVRK3ENSG00000105053.6chr19-5048421150484356504842115048427050491628504917490.100000.000230.00187longerK562AQR
A3SSVRK3ENSG00000105053.6chr19-5049611650496264504961165049620950498070504981760.065000.000050.00043longerK562AQR
MXEVRK3ENSG00000105053.6chr19-50498070504981765049844750498532504961165049620950504046505041110.152000.003270.025211includedK562AQR
MXEVRK3ENSG00000105053.6chr19-5051249250512642505192805051942050510825505110835052384150523904-0.120000.010070.079452includedHepG2SFPQ
MXEVRK3ENSG00000105053.6chr19-50498447504985325050076050500827504980705049817650504046505041110.240000.000100.007521includedK562SBDS
MXEVRK3ENSG00000105053.6chr19-50498070504981765049844750498532504961165049620950504046505041110.401000.000000.000001includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VRK3 is not avaliable on ENCORE database.