ITGAE

General Information

Gene Name       : ITGAE
Gene ID             : ENSG00000083457.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ITGAE)


Antibody Validation


Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ITGAEENSG00000083457.1112.1413.1912.66ENCSR000AEF
HepG2ITGAEENSG00000083457.1126.5027.8027.15ENCSR985KAT
K562ITGAEENSG00000083457.1113.1612.9913.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ITGAE is not avaliable on ENCORE database.



Proteins bound to RNA

  • ITGAE RNA is bound by 5 proteins.  







eCLIP assay for ITGAE is not avaliable on ENCORE database.





5 proteins are bound to ITGAE RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1736179353618023-3'-UTR,intron-Distal,intron-Proximal3.195893.64832HepG2ZC3H11A
chr1736269923627120-CDS,intron-Distal,intron-Proximal3.716633.59926K562DDX3X
chr1736236543623735-CDS,intron-Distal,intron-Proximal4.029158.55689HepG2U2AF2
chr1736265703626669-CDS,intron-Distal,intron-Proximal3.998563.56019HepG2GRWD1
chr1736269223627032-CDS,intron-Distal,intron-Proximal5.7480525.05263HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ITGAE is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ITGAE is not available on ENCORE database.

  • 39 RBPs can affect the levels of ITGAE.  








The Knockdown/knockout RNA-Seq assay for ITGAE is not available on ENCORE database.





39 RBPs can affect the gene expression of ITGAE :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ITGAEENSG00000083457.7211.97770317.02240-0.580702.454901.95080HepG2AKAP1
ITGAEENSG00000083457.7245.53470166.190700.563002.161001.33680HepG2BCCIP
ITGAEENSG00000083457.7107.42320165.99400-0.627802.815402.14560HepG2CKAP4
ITGAEENSG00000083457.7185.54350102.669100.853704.224002.92530HepG2CSTF2
ITGAEENSG00000083457.740.4945081.78630-1.014102.335301.43870HepG2DDX59
ITGAEENSG00000083457.789.30050137.30620-0.620702.231501.59420HepG2DNAJC21
ITGAEENSG00000083457.7111.39040250.79910-1.170907.292306.36350HepG2EIF2S1
ITGAEENSG00000083457.7363.05530281.316400.367902.222601.67400HepG2ETF1
ITGAEENSG00000083457.791.64620142.22830-0.634102.086301.39610HepG2FUBP3
ITGAEENSG00000083457.7181.40450262.58750-0.533602.231601.59960HepG2HNRNPK
ITGAEENSG00000083457.7148.66310263.69300-0.826804.360203.53000HepG2IGF2BP2
ITGAEENSG00000083457.7107.76100156.46410-0.538002.242001.57340HepG2ILF2
ITGAEENSG00000083457.7184.84770255.43040-0.466602.221001.53720HepG2NOL12
ITGAEENSG00000083457.7154.45000256.44260-0.731503.674702.85010HepG2PABPC4
ITGAEENSG00000083457.7150.81590246.07790-0.706304.331703.60180HepG2PCBP1
ITGAEENSG00000083457.7162.03940250.40550-0.627903.430202.83470HepG2PTBP1
ITGAEENSG00000083457.7106.53750169.10760-0.666603.113002.46770HepG2PUS1
ITGAEENSG00000083457.7391.28470235.130900.734705.985005.29530HepG2RBM22
ITGAEENSG00000083457.7145.32230246.11360-0.760104.186103.37210HepG2RBM25
ITGAEENSG00000083457.7478.55190221.379701.1121016.6319015.48260HepG2SRSF9
ITGAEENSG00000083457.7260.08250162.665200.677002.953102.25770HepG2SUPV3L1
ITGAEENSG00000083457.7453.26400244.603400.889809.710408.76260HepG2TAF15
ITGAEENSG00000083457.7144.0694088.110500.709302.315601.73570HepG2U2AF1
ITGAEENSG00000083457.7155.96650252.14850-0.693002.589201.77950HepG2UBE2L3
ITGAEENSG00000083457.7142.9172097.263500.555101.990701.38180HepG2UPF1
ITGAEENSG00000083457.7290.43660148.973100.963104.809003.46870HepG2UPF2
ITGAEENSG00000083457.7158.1797093.904100.752201.923601.40560HepG2UTP3
ITGAEENSG00000083457.7255.97660160.125800.676703.087402.32200HepG2XRN2
ITGAEENSG00000083457.7158.99610106.971200.571702.382501.86400HepG2ZNF622
ITGAEENSG00000083457.7174.08950112.500000.629802.633101.68160K562AKAP8
ITGAEENSG00000083457.7359.31930243.619900.560503.030102.42150K562AQR
ITGAEENSG00000083457.7354.05480207.679000.769503.094202.29790K562GRSF1
ITGAEENSG00000083457.7120.2044062.961100.932903.207002.20010K562HNRNPM
ITGAEENSG00000083457.7169.10650103.760200.704602.786901.98920K562HSPD1
ITGAEENSG00000083457.7192.75720118.264500.704703.527502.57300K562MAGOH
ITGAEENSG00000083457.7129.3651083.363400.633902.122501.40880K562MTPAP
ITGAEENSG00000083457.7147.1495088.772000.729002.224401.45410K562NAA15
ITGAEENSG00000083457.7149.0415092.754700.684102.223801.54730K562PRPF8
ITGAEENSG00000083457.7185.58900114.893800.691703.395902.66890K562PTBP1
ITGAEENSG00000083457.7175.77670105.646600.734402.943802.38690K562PUS1
ITGAEENSG00000083457.7162.95280110.224200.563902.142301.40710K562RBM22
ITGAEENSG00000083457.7184.81350112.623000.714503.140202.39070K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ITGAE is not available on ENCORE database.





20 RBPs can affect the splicing of ITGAE :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.190000.000000.00016excludedHepG2G3BP1
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.206000.000000.00000excludedK562SF3B4
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.102000.002050.06331excludedK562PRPF8
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.079000.001180.06807excludedHepG2RBM22
SEITGAEENSG00000083457.7chr17-3626581362667736236003623696362698136270380.186000.000030.02081includedHepG2DHX30
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.286000.000190.00345excludedHepG2U2AF2
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.209000.000000.00000excludedHepG2AKAP1
SEITGAEENSG00000083457.7chr17-3626581362667736234523623696362698136270380.082000.002340.02502includedK562AQR
SEITGAEENSG00000083457.7chr17-362360036236963619981362009236269813627131-0.065000.006550.05805excludedK562AQR
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627148-0.192000.000000.00004excludedHepG2DDX3X
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.200000.000000.00005excludedHepG2NCBP2
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.192000.000000.00015excludedHepG2MATR3
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.204000.000000.00005excludedK562U2AF1
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.163000.000000.00000excludedHepG2SRSF1
SEITGAEENSG00000083457.7chr17-3626581362667736236003623696362698136270380.156000.000080.01472includedHepG2SSB
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.211000.000010.00190excludedHepG2IGF2BP3
SEITGAEENSG00000083457.7chr17-3626581362667736236003623696362698136270380.164000.000020.00269includedHepG2TIAL1
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627148-0.107000.002440.08998excludedHepG2SF3B4
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.197000.000010.00047excludedK562U2AF2
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.217000.000000.00016excludedK562QKI
SEITGAEENSG00000083457.7chr17-3626581362667736236003623696362698136271480.403000.000010.00097includedHepG2SRSF9
SEITGAEENSG00000083457.7chr17-362658136266773623600362369636269813627038-0.154000.000010.00460excludedK562SERBP1
SEITGAEENSG00000083457.7chr17-3626581362667736236003623696362698136270380.164000.001060.02028includedK562HNRNPC
MXEITGAEENSG00000083457.7chr17-362360036236963626981362703836199813620092363121236313200.418000.000010.000651includedHepG2SRSF9

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ITGAE is not avaliable on ENCORE database.