COG8

General Information

Gene Name       : COG8
Gene ID             : ENSG00000213380.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COG8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COG8ENSG00000213380.158.2611.8910.07ENCSR000AEF
HepG2COG8ENSG00000213380.1524.1423.4223.78ENCSR985KAT
K562COG8ENSG00000213380.1515.9018.7817.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COG8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COG8 RNA is bound by 20 proteins.  







eCLIP assay for COG8 is not avaliable on ENCORE database.





20 proteins are bound to COG8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166936267169362739-3'-UTR,intron-Distal4.432604.42734K562UCHL5
chr166936287269362921-3'-UTR,intron-Distal5.211497.58222HepG2RBM15
chr166936171169361758-3'-UTR,intron-Distal3.027245.23856HepG2STAU2
chr166936246569362507-3'-UTR,intron-Distal,intron-Proximal4.333995.28210HepG2TIA1
chr166936245969362504-3'-UTR,intron-Distal,intron-Proximal4.093784.24308HepG2TIAL1
chr166936245169362500-3'-UTR,intron-Distal,intron-Proximal3.824547.69639K562TIA1
chr166936170869361760-3'-UTR,intron-Distal4.4433618.96223HepG2UPF1
chr166936305869363137-3'-UTR,CDS,intron-Distal3.680394.64775K562SF3B4
chr166936287969362919-3'-UTR,intron-Distal4.047767.36824K562RBM15
chr166936164369361693-3'-UTR,intron-Distal3.201494.26467K562UPF1
chr166936464569364729-3'-UTR,intron-Distal,intron-Proximal4.304703.25089HepG2AQR
chr166936302769363110-3'-UTR,CDS,intron-Distal3.459325.33249HepG2AQR
chr166936211169362186-3'-UTR,intron-Distal4.8569827.69854HepG2UPF1
chr166936188269361949-3'-UTR,intron-Distal4.5773311.55409HepG2UPF1
chr166936303869363137-3'-UTR,CDS,intron-Distal3.207447.41653HepG2BUD13
chr166936260369362664-3'-UTR,intron-Distal,intron-Proximal3.931564.59929HepG2RBM15
chr166936256869362678-3'-UTR,intron-Distal,intron-Proximal3.007524.79429HepG2GRWD1
chr166936164269361708-3'-UTR,intron-Distal4.0611216.58183HepG2UPF1
chr166936277669362831-3'-UTR,intron-Distal4.491315.59408HepG2GRWD1
chr166936868169368744-CDS,intron-Distal5.087537.08875HepG2RBM15
chr166936920769369239-3'-UTR,CDS,intron-Distal,intron-Proximal4.211863.61890HepG2G3BP1
chr166937322669373326-CDS,intron-Distal5.492807.10260HepG2RPS3
chr166935984869359935-intron-Distal3.150485.08243HepG2RBFOX2
chr166936427069364316-CDS,intron-Distal3.750027.94128HepG2DDX3X
chr166936385269363911-CDS,intron-Distal3.576065.13777HepG2PRPF8
chr166936434069364449-CDS,intron-Distal5.0898051.62577HepG2DDX3X
chr166936419869364270-CDS,intron-Distal5.1664719.24828HepG2DDX3X
chr166936436469364450-CDS,intron-Distal3.080763.99662HepG2XPO5
chr166936406969364158-CDS,intron-Distal4.3228423.33219HepG2DDX3X
chr166935992469360044-intron-Distal3.101433.51818HepG2LIN28B
chr166935655469356658-intron-Distal3.423566.27237HepG2IGF2BP1
chr166935526769355345-intron-Distal4.017534.55582HepG2SLTM
chr166936459369364677-intron-Distal,intron-Proximal4.762634.57154HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COG8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COG8 is not available on ENCORE database.

  • 31 RBPs can affect the levels of COG8.  








The Knockdown/knockout RNA-Seq assay for COG8 is not available on ENCORE database.





31 RBPs can affect the gene expression of COG8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COG8ENSG00000213380.9461.98590804.99910-0.801107.306305.67150HepG2AKAP8
COG8ENSG00000213380.91210.707601438.73630-0.249002.608801.93990HepG2AUH
COG8ENSG00000213380.9813.66300647.408500.329702.077601.55380HepG2BOP1
COG8ENSG00000213380.9972.94530831.765700.226102.062401.33310HepG2DDX19B
COG8ENSG00000213380.9641.214801094.87500-0.771902.391301.81340HepG2DDX6
COG8ENSG00000213380.9554.57210664.32660-0.260502.033301.39350HepG2ILF2
COG8ENSG00000213380.91768.855201180.751900.583003.271502.59010HepG2MATR3
COG8ENSG00000213380.9756.51800920.37170-0.282802.184001.58490HepG2PUM2
COG8ENSG00000213380.91082.14560916.100700.240202.258201.68880HepG2PUS1
COG8ENSG00000213380.9909.877501149.28920-0.337002.556601.95220HepG2QKI
COG8ENSG00000213380.9508.28920770.04780-0.599302.812002.10180HepG2RAVER1
COG8ENSG00000213380.91167.886701380.70140-0.241502.192001.71620HepG2RBM22
COG8ENSG00000213380.9937.088901180.89640-0.333602.427001.91470HepG2NELFE
COG8ENSG00000213380.91079.237101559.42170-0.5310010.482409.67700HepG2SRFBP1
COG8ENSG00000213380.91045.52780856.640700.287402.470401.87420HepG2SRSF5
COG8ENSG00000213380.91198.57810974.276800.298803.186002.52800HepG2SUCLG1
COG8ENSG00000213380.91091.22700847.602800.364402.864101.97450HepG2TUFM
COG8ENSG00000213380.9320.00470431.14710-0.430101.984201.34150HepG2UCHL5
COG8ENSG00000213380.9751.90540923.44000-0.296503.147202.57610HepG2ZNF622
COG8ENSG00000213380.9385.11200638.51910-0.729508.999408.05130K562AGGF1
COG8ENSG00000213380.9436.35200701.60230-0.685206.923605.19850K562AKAP8
COG8ENSG00000213380.9486.00910664.39980-0.451103.280802.56750K562AKAP8L
COG8ENSG00000213380.9989.63130789.310900.326202.294601.69230K562DDX47
COG8ENSG00000213380.9746.440701008.26190-0.433803.810502.92820K562GRSF1
COG8ENSG00000213380.9478.44620705.12330-0.559505.009203.83480K562KIF1C
COG8ENSG00000213380.9518.00960674.95290-0.381802.375401.40530K562MAK16
COG8ENSG00000213380.9539.71080789.91220-0.549504.992203.69940K562MBNL1
COG8ENSG00000213380.9364.23510553.66870-0.604203.382502.38760K562NAA15
COG8ENSG00000213380.9746.96480510.103600.550205.509204.59950K562PTBP1
COG8ENSG00000213380.9263.38130658.96160-1.3230017.9878016.63890K562PUS1
COG8ENSG00000213380.9343.54590642.00970-0.9021011.8337010.61340K562RBM15
COG8ENSG00000213380.9235.10770372.58430-0.664203.487502.22860K562U2AF1
COG8ENSG00000213380.9250.38000384.68830-0.619604.485903.46850K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COG8 is not available on ENCORE database.






No RBPs affect the alternative splcing events of COG8 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for COG8 is not avaliable on ENCORE database.