SLC6A6

General Information

Gene Name : SLC6A6
Gene ID : ENSG00000131389.17
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SLC6A6)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SLC6A6	ENSG00000131389.17	16.25	19.42	17.84	ENCSR000AEF
HepG2	SLC6A6	ENSG00000131389.17	15.42	13.99	14.71	ENCSR985KAT
K562	SLC6A6	ENSG00000131389.17	87.70	93.27	90.48	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SLC6A6 is not avaliable on ENCORE database.

Proteins bound to RNA

SLC6A6 RNA is bound by 31 proteins.

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eCLIP assay for SLC6A6 is not avaliable on ENCORE database.

31 proteins are bound to SLC6A6 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	14513789	14513826	+	3'-UTR,CDS,intron-Proximal	4.51715	39.92129	K562	DDX24
chr3	14526654	14526753	+	3'-UTR	4.18521	37.90633	K562	TARDBP
chr3	14444759	14444866	+	intron-Distal	5.53990	35.80916	K562	TARDBP
chr3	14518712	14518742	+	3'-UTR,CDS,intron-Distal,intron-Proximal	5.27100	33.98957	K562	DDX24
chr3	14457754	14457828	+	intron-Distal,intron-Proximal	6.50098	32.07898	K562	EIF4G2
chr3	14509371	14509463	+	CDS	4.94677	31.93293	K562	DDX24
chr3	14520094	14520160	+	3'-UTR,intron-Distal,intron-Proximal	4.96154	30.96912	K562	TIA1
chr3	14487251	14487359	+	3'-UTR,CDS	3.74670	27.98661	K562	DDX24
chr3	14509649	14509707	+	CDS,intron-Distal	4.88564	27.25736	K562	DDX24
chr3	14444864	14444926	+	intron-Distal	4.82406	24.42544	K562	EIF4G2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 156 entries

eCLIP assay for SLC6A6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SLC6A6 is not available on ENCORE database.
139 RBPs can affect the levels of SLC6A6.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SLC6A6 is not available on ENCORE database.

139 RBPs can affect the gene expression of SLC6A6 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SLC6A6	ENSG00000131389.12	3044.84290	10038.66720	-1.72110	99.07660	95.75320	K562	DDX47
SLC6A6	ENSG00000131389.12	3193.53830	1164.44360	1.45540	89.93350	87.71300	HepG2	SRSF9
SLC6A6	ENSG00000131389.12	1101.10580	5369.42900	-2.28580	76.13790	72.46340	K562	RPS19
SLC6A6	ENSG00000131389.12	438.66610	1278.57660	-1.54330	59.80180	57.71000	HepG2	PUS1
SLC6A6	ENSG00000131389.12	768.17790	1891.48100	-1.30000	54.03160	52.47090	HepG2	SSB
SLC6A6	ENSG00000131389.12	1787.00570	5271.76360	-1.56070	49.93810	47.02290	K562	PRPF8
SLC6A6	ENSG00000131389.12	2653.10910	6020.19800	-1.18210	44.25750	41.54870	K562	POLR2G
SLC6A6	ENSG00000131389.12	4965.52770	8476.49580	-0.77150	41.81500	39.31470	K562	WDR43
SLC6A6	ENSG00000131389.12	6613.03000	13056.23960	-0.98140	40.64860	37.61330	K562	EIF4G2
SLC6A6	ENSG00000131389.12	1098.83570	4507.80640	-2.03640	35.12490	32.08580	K562	EIF3A
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 174 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SLC6A6 is not available on ENCORE database.

21 RBPs can affect the splicing of SLC6A6 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	SLC6A6	ENSG00000131389.12	chr3	+	14521627	14521746			14520592	14520693	14523178	14523349	0.11100	0.00000	included	K562	SRSF1
SE	SLC6A6	ENSG00000131389.12	chr3	+	14509595	14509720			14509360	14509464	14513712	14513825	-0.19200	0.00000	excluded	K562	SF3B4
SE	SLC6A6	ENSG00000131389.12	chr3	+	14509595	14509720			14509360	14509464	14513712	14513825	-0.15800	0.00006	excluded	K562	FXR1
SE	SLC6A6	ENSG00000131389.12	chr3	+	14487224	14487359			14485131	14485371	14489089	14489324	-0.06800	0.00080	excluded	K562	SUPV3L1
SE	SLC6A6	ENSG00000131389.12	chr3	+	14486245	14486374			14485131	14485371	14487224	14487359	-0.09900	0.00000	excluded	K562	PUS1
SE	SLC6A6	ENSG00000131389.12	chr3	+	14521627	14521746			14520592	14520693	14523178	14523349	0.05300	0.00015	included	K562	U2AF2
SE	SLC6A6	ENSG00000131389.12	chr3	+	14521627	14521746			14520592	14520693	14523178	14523349	0.11700	0.00000	included	K562	HNRNPK
SE	SLC6A6	ENSG00000131389.12	chr3	+	14509595	14509720			14509360	14509464	14513712	14513825	-0.21000	0.00000	excluded	K562	HNRNPK
SE	SLC6A6	ENSG00000131389.12	chr3	+	14509595	14509720			14509360	14509464	14513712	14513825	-0.29600	0.00016	excluded	K562	HNRNPC
MXE	SLC6A6	ENSG00000131389.12	chr3	+	14485135	14485371	14487224	14487359	14457919	14457961	14489089	14489324	0.06400	0.00023	1included	K562	SUPV3L1

Showing 1 to 10 of 30 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SLC6A6

General Information

Functions

Localization

Domains (AlphaFold: SLC6A6)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SLC6A6 is not avaliable on ENCORE database.

31 proteins are bound to SLC6A6 RNA:

eCLIP assay for SLC6A6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SLC6A6 is not available on ENCORE database.

139 RBPs can affect the gene expression of SLC6A6 :

The Knockdown/knockout RNA-Seq assay for SLC6A6 is not available on ENCORE database.

21 RBPs can affect the splicing of SLC6A6 :

The Knockdown/knockout RNA-Seq assay for SLC6A6 is not avaliable on ENCORE database.