MAP2K1

General Information

Gene Name : MAP2K1
Gene ID : ENSG00000169032.9
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MAP2K1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MAP2K1	ENSG00000169032.9	26.23	32.14	29.19	ENCSR000AEF
HepG2	MAP2K1	ENSG00000169032.9	16.89	26.52	21.70	ENCSR985KAT
K562	MAP2K1	ENSG00000169032.9	30.54	27.87	29.20	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MAP2K1 is not avaliable on ENCORE database.

Proteins bound to RNA

MAP2K1 RNA is bound by 28 proteins.

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eCLIP assay for MAP2K1 is not avaliable on ENCORE database.

28 proteins are bound to MAP2K1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	66679301	66679368	+	5'-UTR	4.48215	29.90724	HepG2	DDX3X
chr15	66783724	66783779	+	3'-UTR	4.97321	27.36324	K562	PUM2
chr15	66679368	66679443	+	5'-UTR	3.86245	24.20352	HepG2	DDX3X
chr15	66783787	66783861	+	3'-UTR	5.49084	22.45467	K562	QKI
chr15	66679545	66679634	+	5'-UTR	5.50320	19.67840	HepG2	DDX3X
chr15	66783705	66783782	+	3'-UTR	5.81504	13.07555	K562	IGF2BP1
chr15	66679345	66679427	+	5'-UTR	3.00307	12.78795	K562	DDX3X
chr15	66783137	66783216	+	3'-UTR	4.71224	12.38199	HepG2	FUBP3
chr15	66679272	66679345	+	5'-UTR	4.11582	11.03951	K562	DDX3X
chr15	66727435	66727550	+	CDS	3.15332	10.93472	K562	ZNF622
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 46 entries

eCLIP assay for MAP2K1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MAP2K1 is not available on ENCORE database.
116 RBPs can affect the levels of MAP2K1.

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The Knockdown/knockout RNA-Seq assay for MAP2K1 is not available on ENCORE database.

116 RBPs can affect the gene expression of MAP2K1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MAP2K1	ENSG00000169032.5	496.48710	1169.19610	-1.23570	34.31240	32.61900	HepG2	DKC1
MAP2K1	ENSG00000169032.5	882.06300	1793.77630	-1.02400	33.35250	32.10890	HepG2	SRSF1
MAP2K1	ENSG00000169032.5	366.57800	956.95290	-1.38430	31.41070	30.05570	HepG2	TIAL1
MAP2K1	ENSG00000169032.5	596.18350	1776.10020	-1.57490	30.19630	28.12550	HepG2	EIF4A3
MAP2K1	ENSG00000169032.5	2611.85470	1558.80750	0.74450	25.30530	24.18790	HepG2	SRFBP1
MAP2K1	ENSG00000169032.5	1001.38610	1837.00790	-0.87540	24.03020	22.75010	HepG2	NELFE
MAP2K1	ENSG00000169032.5	387.36370	991.35930	-1.35570	24.26390	22.44780	HepG2	HNRNPC
MAP2K1	ENSG00000169032.5	531.56100	1214.83110	-1.19240	23.74450	22.06710	K562	HNRNPC
MAP2K1	ENSG00000169032.5	957.12050	1710.92440	-0.83800	22.24410	20.78610	HepG2	RECQL
MAP2K1	ENSG00000169032.5	206.17270	517.11320	-1.32660	21.94400	20.13290	HepG2	PRPF4
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 132 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MAP2K1 is not available on ENCORE database.

6 RBPs can affect the splicing of MAP2K1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MAP2K1	ENSG00000169032.5	chr15	+	66782055	66782101			66781572	66781614	66782839	66784650	-0.10500	0.00000	0.00017	excluded	K562	SF3B4
SE	MAP2K1	ENSG00000169032.5	chr15	+	66782055	66782101			66781552	66781614	66782839	66784650	-0.17100	0.00000	0.00000	excluded	K562	U2AF2
SE	MAP2K1	ENSG00000169032.5	chr15	+	66735617	66735695			66729083	66729230	66736993	66737045	-0.08800	0.00000	0.00007	excluded	K562	U2AF2
MXE	MAP2K1	ENSG00000169032.5	chr15	+	66736875	66737045	66777327	66777529	66735617	66735695	66779565	66779630	0.11300	0.00000	0.00000	1included	K562	AQR
SE	MAP2K1	ENSG00000169032.5	chr15	+	66782055	66782101			66781552	66781614	66782839	66784650	-0.07300	0.00001	0.00031	excluded	K562	AQR
MXE	MAP2K1	ENSG00000169032.5	chr15	+	66774092	66774217	66779565	66779630	66745791	66745881	66781552	66781614	-0.20600	0.00002	0.00069	2included	HepG2	SRSF1
MXE	MAP2K1	ENSG00000169032.5	chr15	+	66781572	66781614	66782055	66782101	66779565	66779630	66782839	66783681	0.13200	0.00002	0.00061	1included	K562	SF3B4
MXE	MAP2K1	ENSG00000169032.5	chr15	+	66781552	66781614	66782055	66782101	66779565	66779630	66782839	66784650	-0.08400	0.00003	0.00288	2included	K562	SBDS
SE	MAP2K1	ENSG00000169032.5	chr15	+	66774092	66774217			66736993	66737045	66777327	66777541	-0.07700	0.00005	0.00101	excluded	K562	AQR
SE	MAP2K1	ENSG00000169032.5	chr15	+	66735617	66735695			66729083	66729230	66736993	66737045	-0.12900	0.00011	0.00217	excluded	HepG2	U2AF2

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MAP2K1

General Information

Functions

Localization

Domains (AlphaFold: MAP2K1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MAP2K1 is not avaliable on ENCORE database.

28 proteins are bound to MAP2K1 RNA:

eCLIP assay for MAP2K1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MAP2K1 is not available on ENCORE database.

116 RBPs can affect the gene expression of MAP2K1 :

The Knockdown/knockout RNA-Seq assay for MAP2K1 is not available on ENCORE database.

6 RBPs can affect the splicing of MAP2K1 :

The Knockdown/knockout RNA-Seq assay for MAP2K1 is not avaliable on ENCORE database.