A2M

General Information

Gene Name : A2M
Gene ID : ENSG00000175899.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: A2M)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	A2M	ENSG00000175899.14	0.00	0.00	0.00	ENCSR000AEF
HepG2	A2M	ENSG00000175899.14	1236.35	1213.15	1224.75	ENCSR985KAT
K562	A2M	ENSG00000175899.14	0.00	0.00	0.00	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for A2M is not avaliable on ENCORE database.

Proteins bound to RNA

A2M RNA is bound by 43 proteins.

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eCLIP assay for A2M is not avaliable on ENCORE database.

43 proteins are bound to A2M RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	9246091	9246100	-	3'-UTR,CDS,intron-Distal	4.11565	400.00000	HepG2	SND1
chr12	9261952	9261978	-	3'-UTR,CDS,intron-Distal	3.44900	400.00000	HepG2	BCLAF1
chr12	9246135	9246169	-	3'-UTR,CDS,intron-Distal	3.36361	400.00000	HepG2	RPS3
chr12	9262485	9262567	-	3'-UTR,CDS,intron-Distal	3.15953	400.00000	HepG2	ZNF800
chr12	9246100	9246134	-	3'-UTR,CDS,intron-Distal	3.69577	400.00000	HepG2	SND1
chr12	9220393	9220408	-	3'-UTR,CDS,intron-Distal	3.74129	400.00000	HepG2	LARP4
chr12	9220374	9220393	-	3'-UTR,CDS,intron-Distal	3.88620	400.00000	HepG2	LARP4
chr12	9243997	9244025	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.26237	400.00000	HepG2	RPS3
chr12	9261934	9261952	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.59232	400.00000	HepG2	BCLAF1
chr12	9243977	9244000	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.69231	400.00000	HepG2	LIN28B
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 611 entries

eCLIP assay for A2M is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for A2M is not available on ENCORE database.
148 RBPs can affect the levels of A2M.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for A2M is not available on ENCORE database.

148 RBPs can affect the gene expression of A2M :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
A2M	ENSG00000175899.10	23.34730	1349.58780	-5.85310	99999.99999	99999.99999	K562	SRPK2
A2M	ENSG00000175899.10	2.44110	1259.55220	-9.01120	99999.99999	99999.99999	K562	WDR43
A2M	ENSG00000175899.10	49.70440	1415.59650	-4.83190	274.38580	270.27910	K562	UPF1
A2M	ENSG00000175899.10	21.22190	1317.29270	-5.95590	272.91470	268.80880	K562	SF3A3
A2M	ENSG00000175899.10	1.03550	1211.28810	-10.19200	264.13670	260.04080	K562	WDR3
A2M	ENSG00000175899.10	6.00380	1231.59150	-7.68040	260.72670	256.64080	K562	NUFIP2
A2M	ENSG00000175899.10	28.86080	1201.53660	-5.37960	245.42250	241.49410	K562	MTPAP
A2M	ENSG00000175899.10	80956.22080	259919.42600	-1.68290	235.31500	231.78040	HepG2	PUS1
A2M	ENSG00000175899.10	82479.58880	400422.55630	-2.27940	121.57190	119.60030	HepG2	SRSF1
A2M	ENSG00000175899.10	336514.10120	71618.48320	2.23220	85.96830	83.01420	HepG2	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 157 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for A2M is not available on ENCORE database.

13 RBPs can affect the splicing of A2M :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	A2M	ENSG00000175899.10	chr12	-	9264904	9265123			9264754	9264807	9265955	9266139	0.55300	0.00000	0.00000	included	HepG2	HNRNPK
RI	A2M	ENSG00000175899.10	chr12	-	9265105	9265285			9265105	9265132	9265230	9265285	0.39500	0.00000	0.00000	included	HepG2	U2AF2
RI	A2M	ENSG00000175899.10	chr12	-	9220307	9220820			9220307	9220435	9220778	9220820	0.06400	0.00000	0.00000	included	HepG2	U2AF2
MXE	A2M	ENSG00000175899.10	chr12	-	9251202	9251352	9252061	9252119	9248134	9248296	9253739	9253803	0.11900	0.00000	0.00009	1included	HepG2	TAF15
MXE	A2M	ENSG00000175899.10	chr12	-	9257944	9258098	9258423	9258561	9256834	9256996	9258831	9258892	-0.87500	0.00000	0.00000	2included	HepG2	U2AF2
MXE	A2M	ENSG00000175899.10	chr12	-	9257944	9258098	9258423	9258520	9256834	9256996	9258831	9258892	-0.84500	0.00000	0.00001	2included	HepG2	U2AF2
MXE	A2M	ENSG00000175899.10	chr12	-	9251202	9251352	9252061	9252119	9248134	9248296	9253739	9253803	-0.10600	0.00001	0.00056	2included	HepG2	HNRNPL
MXE	A2M	ENSG00000175899.10	chr12	-	9257944	9258098	9258423	9258520	9256834	9256996	9258831	9258892	-0.45200	0.00003	0.00136	2included	HepG2	HNRNPUL1
MXE	A2M	ENSG00000175899.10	chr12	-	9251202	9251352	9252061	9252119	9248134	9248296	9253739	9253803	-0.09400	0.00003	0.00223	2included	HepG2	HNRNPU
MXE	A2M	ENSG00000175899.10	chr12	-	9257944	9258098	9258423	9258516	9256834	9256996	9258831	9258892	-0.44100	0.00004	0.00141	2included	HepG2	HNRNPUL1

Showing 1 to 10 of 21 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

A2M

General Information

Functions

Localization

Domains (AlphaFold: A2M)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for A2M is not avaliable on ENCORE database.

43 proteins are bound to A2M RNA:

eCLIP assay for A2M is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for A2M is not available on ENCORE database.

148 RBPs can affect the gene expression of A2M :

The Knockdown/knockout RNA-Seq assay for A2M is not available on ENCORE database.

13 RBPs can affect the splicing of A2M :

The Knockdown/knockout RNA-Seq assay for A2M is not avaliable on ENCORE database.