PCSK6

General Information

Gene Name : PCSK6
Gene ID : ENSG00000140479.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PCSK6)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PCSK6	ENSG00000140479.16	0.00	0.00	0.00	ENCSR000AEF
HepG2	PCSK6	ENSG00000140479.16	102.11	54.35	78.23	ENCSR985KAT
K562	PCSK6	ENSG00000140479.16	12.64	13.78	13.21	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PCSK6 is not avaliable on ENCORE database.

Proteins bound to RNA

PCSK6 RNA is bound by 54 proteins.

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eCLIP assay for PCSK6 is not avaliable on ENCORE database.

54 proteins are bound to PCSK6 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	101851807	101851891	-	intron-Distal	8.90111	124.52391	HepG2	FAM120A
chr15	101999590	101999776	-	intron-Distal	6.61251	60.40272	HepG2	FAM120A
chr15	101851804	101851887	-	intron-Distal	6.39649	48.74927	HepG2	CSTF2T
chr15	102029816	102029896	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.87392	36.01930	HepG2	DDX3X
chr15	101999624	101999646	-	intron-Distal	5.33944	22.32322	HepG2	CSTF2T
chr15	101999646	101999705	-	intron-Distal	6.25104	21.78156	HepG2	CSTF2T
chr15	102029672	102029798	-	CDS,intron-Distal,intron-Proximal	3.35599	21.21847	HepG2	DDX3X
chr15	101851809	101851882	-	intron-Distal	6.02776	19.69269	HepG2	PRPF4
chr15	101999578	101999624	-	intron-Distal	5.20641	19.09961	HepG2	CSTF2T
chr15	101868896	101868991	-	intron-Distal	4.71475	17.89897	HepG2	HLTF
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 245 entries

eCLIP assay for PCSK6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PCSK6 is not available on ENCORE database.
130 RBPs can affect the levels of PCSK6.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PCSK6 is not available on ENCORE database.

130 RBPs can affect the gene expression of PCSK6 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PCSK6	ENSG00000140479.12	833.67590	3616.64550	-2.11710	136.15730	133.67770	HepG2	RBM22
PCSK6	ENSG00000140479.12	9495.12840	4867.75040	0.96380	81.63010	79.74280	HepG2	ZNF622
PCSK6	ENSG00000140479.12	1906.58030	4359.63890	-1.19320	64.30370	62.48450	HepG2	PTBP1
PCSK6	ENSG00000140479.12	6072.99220	1817.01520	1.74070	62.26270	59.71890	HepG2	CPSF6
PCSK6	ENSG00000140479.12	2442.05110	4737.74290	-0.95610	49.63310	48.17790	HepG2	SRSF1
PCSK6	ENSG00000140479.12	5958.61790	1965.47870	1.60000	49.48220	47.33920	HepG2	HNRNPLL
PCSK6	ENSG00000140479.12	1320.15600	4526.21180	-1.77760	45.87900	43.57660	HepG2	MATR3
PCSK6	ENSG00000140479.12	1732.78810	3693.62560	-1.09190	41.30570	39.48350	HepG2	PUS1
PCSK6	ENSG00000140479.12	4757.44600	1979.27460	1.26510	36.28230	34.55050	HepG2	BOP1
PCSK6	ENSG00000140479.12	5091.35170	3183.75050	0.67720	32.31410	30.45080	HepG2	SLBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 145 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PCSK6 is not available on ENCORE database.

22 RBPs can affect the splicing of PCSK6 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	PCSK6	ENSG00000140479.12	chr15	-	101871855	101871894	101866581	101866684	101872056	101872236	-0.39400	0.00000	0.00000	excluded	HepG2	U2AF1
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.15200	0.00000	0.00075	included	HepG2	AKAP1
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.24600	0.00000	0.00000	included	HepG2	FTO
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.19200	0.00000	0.00006	included	HepG2	TIAL1
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.23500	0.00000	0.00000	included	HepG2	SUPV3L1
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.15700	0.00000	0.00001	included	HepG2	SF3B4
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.17300	0.00000	0.00004	included	HepG2	KHSRP
SE	PCSK6	ENSG00000140479.12	chr15	-	101871855	101871894	101866581	101866684	101872056	101872236	-0.17700	0.00001	0.00178	excluded	HepG2	AKAP1
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.16900	0.00001	0.00179	included	HepG2	NCBP2
SE	PCSK6	ENSG00000140479.12	chr15	-	101971524	101971668	101970191	101970268	101972194	101972305	0.18000	0.00001	0.00105	included	HepG2	HNRNPU

Showing 1 to 10 of 25 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PCSK6

General Information

Functions

Localization

Domains (AlphaFold: PCSK6)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PCSK6 is not avaliable on ENCORE database.

54 proteins are bound to PCSK6 RNA:

eCLIP assay for PCSK6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PCSK6 is not available on ENCORE database.

130 RBPs can affect the gene expression of PCSK6 :

The Knockdown/knockout RNA-Seq assay for PCSK6 is not available on ENCORE database.

22 RBPs can affect the splicing of PCSK6 :

The Knockdown/knockout RNA-Seq assay for PCSK6 is not avaliable on ENCORE database.