NEK3

General Information

Gene Name : NEK3
Gene ID : ENSG00000136098.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: NEK3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	NEK3	ENSG00000136098.16	7.69	6.31	7.00	ENCSR000AEF
HepG2	NEK3	ENSG00000136098.16	26.37	35.76	31.06	ENCSR985KAT
K562	NEK3	ENSG00000136098.16	6.32	6.90	6.61	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for NEK3 is not avaliable on ENCORE database.

Proteins bound to RNA

NEK3 RNA is bound by 14 proteins.

CanvasJS.com

eCLIP assay for NEK3 is not avaliable on ENCORE database.

14 proteins are bound to NEK3 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr13	52731570	52731699	-	5'-UTR,intron-Distal,intron-Proximal	3.66068	20.35120	HepG2	HNRNPL
chr13	52725282	52725368	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.80756	15.79153	HepG2	BCLAF1
chr13	52728047	52728113	-	5'-UTR,CDS,intron-Distal	5.19886	12.89578	HepG2	BCLAF1
chr13	52725458	52725525	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.72794	11.08513	HepG2	PPIG
chr13	52707825	52707875	-	3'-UTR,CDS,intron-Distal	3.87603	10.35753	HepG2	BCLAF1
chr13	52707237	52707363	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.81177	10.30537	HepG2	PABPN1
chr13	52726798	52726826	-	5'-UTR,CDS,intron-Distal	5.43844	9.78817	HepG2	BCLAF1
chr13	52730334	52730396	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.88440	9.59205	HepG2	U2AF2
chr13	52707278	52707364	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.10390	9.21862	HepG2	PPIG
chr13	52707317	52707365	-	3'-UTR,CDS,intron-Distal	3.10005	8.71292	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 35 entries

eCLIP assay for NEK3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for NEK3 is not available on ENCORE database.
138 RBPs can affect the levels of NEK3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for NEK3 is not available on ENCORE database.

138 RBPs can affect the gene expression of NEK3 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
NEK3	ENSG00000136098.12	248.69320	1645.48550	-2.72610	156.48160	154.27840	HepG2	SSB
NEK3	ENSG00000136098.12	363.99250	1170.55910	-1.68520	48.01780	46.41080	HepG2	TIAL1
NEK3	ENSG00000136098.12	346.72390	1046.78230	-1.59410	47.94810	46.03640	HepG2	DKC1
NEK3	ENSG00000136098.12	594.14830	1575.63490	-1.40700	34.96430	33.14310	HepG2	PUF60
NEK3	ENSG00000136098.12	472.98150	1299.59980	-1.45820	31.61220	29.97140	HepG2	BOP1
NEK3	ENSG00000136098.12	550.11390	1402.00740	-1.34970	29.21330	27.50750	HepG2	RPLP0
NEK3	ENSG00000136098.12	475.56190	1290.65280	-1.44040	27.19300	25.55900	HepG2	HNRNPLL
NEK3	ENSG00000136098.12	421.26220	1090.26910	-1.37190	26.73650	25.10210	HepG2	HNRNPA1
NEK3	ENSG00000136098.12	516.61870	1444.78570	-1.48370	25.35110	23.12190	HepG2	ABCF1
NEK3	ENSG00000136098.12	523.48930	1193.09190	-1.18850	19.92020	18.28830	HepG2	CPSF6
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 165 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for NEK3 is not available on ENCORE database.

9 RBPs can affect the splicing of NEK3 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	NEK3	ENSG00000136098.12	chr13	-	52709864	52709999			52707824	52707951	52710251	52710395	-0.17100	0.00000	0.00000	excluded	HepG2	U2AF1
SE	NEK3	ENSG00000136098.12	chr13	-	52728214	52728308			52728029	52728127	52730209	52731620	-0.33500	0.00000	0.00000	excluded	HepG2	U2AF2
A3SS	NEK3	ENSG00000136098.12	chr13	-	52728029	52728156			52728029	52728127	52728214	52728308	0.23600	0.00000	0.00000	longer	HepG2	SF3A3
MXE	NEK3	ENSG00000136098.12	chr13	-	52722549	52722604	52725280	52725367	52718825	52719026	52725459	52725527	-0.33400	0.00000	0.00000	2included	HepG2	U2AF2
A3SS	NEK3	ENSG00000136098.12	chr13	-	52728029	52728145			52728029	52728127	52728214	52728290	0.07500	0.00002	0.00324	longer	HepG2	RBM22
SE	NEK3	ENSG00000136098.12	chr13	-	52718825	52719026			52718050	52718122	52722549	52722604	-0.08300	0.00014	0.01426	excluded	HepG2	FTO
SE	NEK3	ENSG00000136098.12	chr13	-	52709864	52709999			52707824	52707951	52710251	52710395	-0.07000	0.00016	0.00288	excluded	HepG2	U2AF2
SE	NEK3	ENSG00000136098.12	chr13	-	52715155	52715206			52710935	52711038	52718050	52718122	0.26000	0.00016	0.01006	included	HepG2	MATR3
SE	NEK3	ENSG00000136098.12	chr13	-	52715155	52715205			52710935	52711038	52718050	52718122	0.29100	0.00020	0.02427	included	HepG2	G3BP1
SE	NEK3	ENSG00000136098.12	chr13	-	52715155	52715206			52710935	52711038	52718050	52718122	0.22100	0.00081	0.05632	included	HepG2	IGF2BP3

Showing 1 to 10 of 14 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

NEK3

General Information

Functions

Localization

Domains (AlphaFold: NEK3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for NEK3 is not avaliable on ENCORE database.

14 proteins are bound to NEK3 RNA:

eCLIP assay for NEK3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for NEK3 is not available on ENCORE database.

138 RBPs can affect the gene expression of NEK3 :

The Knockdown/knockout RNA-Seq assay for NEK3 is not available on ENCORE database.

9 RBPs can affect the splicing of NEK3 :

The Knockdown/knockout RNA-Seq assay for NEK3 is not avaliable on ENCORE database.