LLGL2

General Information

Gene Name       : LLGL2
Gene ID             : ENSG00000073350.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LLGL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LLGL2ENSG00000073350.130.016.733.37ENCSR000AEF
HepG2LLGL2ENSG00000073350.1369.978.4539.21ENCSR985KAT
K562LLGL2ENSG00000073350.1310.622.526.57ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LLGL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LLGL2 RNA is bound by 20 proteins.  







eCLIP assay for LLGL2 is not avaliable on ENCORE database.





20 proteins are bound to LLGL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177356956173569623+3'-UTR,CDS,intron-Proximal3.185874.37509HepG2PABPN1
chr177356644473566578+3'-UTR,CDS3.1658911.71095HepG2PABPN1
chr177356604273566052+3'-UTR,CDS,intron-Proximal3.173688.29694HepG2PPIG
chr177356799073568033+3'-UTR,CDS3.383258.56673HepG2PPIG
chr177356955473569587+3'-UTR,CDS,intron-Proximal3.735257.16658HepG2PRPF8
chr177356910073569181+3'-UTR,CDS4.153877.96022HepG2PABPN1
chr177356644473566568+3'-UTR,CDS4.576215.07810HepG2ZNF800
chr177356703073567066+3'-UTR,CDS,intron-Proximal3.576777.72793HepG2PPIG
chr177356650473566557+3'-UTR,CDS3.9614118.84977HepG2PPIG
chr177356652573566583+3'-UTR,CDS,intron-Proximal3.152333.02345K562ZNF622
chr177356605273566072+3'-UTR,CDS3.6217612.80490HepG2PPIG
chr177356774673567781+3'-UTR,CDS,intron-Proximal3.780635.33036HepG2PABPN1
chr177356917673569215+3'-UTR,CDS3.766867.98982HepG2PPIG
chr177357073473570748+3'-UTR,CDS3.591136.41974HepG2PPIG
chr177356716273567244+3'-UTR,CDS,intron-Proximal3.241273.90373HepG2AQR
chr177356058873560638+3'-UTR,CDS,intron-Proximal3.057965.41015HepG2AQR
chr177357029373570340+3'-UTR,5'-UTR,CDS,intron-Proximal3.965246.35686HepG2PABPN1
chr177356715373567181+3'-UTR,CDS3.695335.60462HepG2PABPN1
chr177356655773566578+3'-UTR,CDS3.5309812.54082HepG2PPIG
chr177356925273569317+3'-UTR,CDS4.672086.12579HepG2PABPN1
chr177356964973569711+3'-UTR,CDS3.873406.62324HepG2PABPN1
chr177356780373567860+3'-UTR,CDS4.8880117.45473HepG2PPIG
chr177356061173560746+3'-UTR,CDS,intron-Distal,intron-Proximal3.911285.77413K562DDX24
chr177357048673570583+3'-UTR,CDS,intron-Distal,intron-Proximal3.682493.09957HepG2AQR
chr177357050273570543+3'-UTR,CDS,intron-Distal,intron-Proximal4.309486.50183HepG2PRPF8
chr177356769673567762+3'-UTR,CDS,intron-Proximal4.974973.93614HepG2AQR
chr177357005573570107+3'-UTR,CDS,intron-Proximal4.995409.50259HepG2EFTUD2
chr177357121373571265+3'-UTR4.123703.88553HepG2ZC3H11A
chr177356813373568195+3'-UTR,CDS,intron-Proximal4.3729615.19374HepG2PRPF8
chr177356605573566131+3'-UTR,CDS3.208157.09653HepG2PABPN1
chr177356914373569249+3'-UTR,CDS3.790146.91167HepG2GRWD1
chr177357003273570060+3'-UTR,CDS,intron-Proximal4.529385.58993HepG2PABPN1
chr177356909773569125+3'-UTR,CDS3.283956.89519HepG2PPIG
chr177356607273566141+3'-UTR,CDS4.2472619.65082HepG2PPIG
chr177357004773570095+3'-UTR,CDS,intron-Proximal5.5664710.62525HepG2PRPF8
chr177356061673560676+3'-UTR,CDS,intron-Proximal4.353933.96990K562BUD13
chr177356534973565407+5'-UTR,CDS,intron-Proximal4.1226622.71420HepG2PPIG
chr177356534973565406+5'-UTR,CDS3.284867.64256HepG2PABPN1
chr177354221473542315+5'-UTR,intron-Distal4.593516.03756HepG2FAM120A
chr177356531073565349+5'-UTR,CDS3.532728.81096HepG2PPIG
chr177352187273521951+5'-UTR,intron-Distal,intron-Proximal3.8188416.25866HepG2PRPF8
chr177355981373559895+CDS,intron-Proximal3.812533.62357HepG2U2AF2
chr177355925873559295+CDS,intron-Proximal4.1091314.54484HepG2SSB
chr177355544073555491+CDS3.9575216.79588HepG2PPIG
chr177356452673564594+CDS,intron-Distal,intron-Proximal4.436578.84794HepG2AQR
chr177355909673559169+CDS,intron-Proximal3.6947015.47743HepG2PPIG
chr177355941373559541+CDS3.417325.77496K562DDX24
chr177355921373559259+CDS3.833359.58474HepG2PPIG
chr177355941273559468+CDS4.4586117.58977HepG2PPIG
chr177356452873564604+CDS,intron-Distal,intron-Proximal4.376694.76200K562BUD13
chr177355950073559602+CDS,intron-Proximal4.1649522.20346HepG2PRPF8
chr177357019173570253+CDS,intron-Distal,intron-Proximal5.2878811.65593HepG2EFTUD2
chr177356471073564770+CDS,intron-Proximal3.4696413.60410HepG2PPIG
chr177355925673559302+CDS,intron-Proximal4.099473.75065K562SSB
chr177357015073570231+CDS,intron-Distal,intron-Proximal4.153613.63122HepG2PRPF4
chr177356453773564604+CDS,intron-Distal,intron-Proximal4.3311510.16714K562AQR
chr177356455073564620+CDS,intron-Distal,intron-Proximal4.370768.51520K562DDX24
chr177356448673564559+CDS,intron-Distal,intron-Proximal5.8440445.82226HepG2SF3A3
chr177355467073554706+CDS3.091937.84823HepG2PPIG
chr177355533473555341+CDS3.031784.09741HepG2PPIG
chr177357038073570455+intron-Distal,intron-Proximal3.9398410.36846HepG2PRPF8
chr177357037073570449+intron-Distal,intron-Proximal4.204228.17769HepG2PRPF4
chr177357045873570521+intron-Distal,intron-Proximal5.1269210.21769HepG2EFTUD2
chr177356418573564276+intron-Distal4.192203.83824K562BUD13
chr177357038373570454+intron-Distal,intron-Proximal3.944663.03048HepG2GTF2F1
chr177357037073570449+intron-Distal,intron-Proximal3.436836.94246HepG2FAM120A
chr177356429673564370+intron-Distal4.168253.55598HepG2ZC3H11A
chr177357037973570458+intron-Distal,intron-Proximal7.1753520.05287HepG2EFTUD2
chr177354701173547134+intron-Distal4.077813.89149HepG2HNRNPK
chr177356730273567345+intron-Distal5.419405.96317HepG2EFTUD2
chr177357037773570447+intron-Distal,intron-Proximal4.370323.25089HepG2AQR
chr177356935973569404+intron-Proximal3.7533310.63457HepG2PRPF8
chr177356720973567256+intron-Proximal3.741923.15816HepG2PRPF4
chr177355929573559308+intron-Proximal5.3742123.15789HepG2SSB
chr177355925973559361+intron-Proximal4.327185.41983K562LIN28B
chr177356720273567275+intron-Proximal4.8226510.18833HepG2EFTUD2
chr177356954373569554+intron-Proximal3.976195.31213HepG2PRPF8
chr177356720473567280+intron-Proximal3.373053.76326HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LLGL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LLGL2 is not available on ENCORE database.

  • 108 RBPs can affect the levels of LLGL2.  








The Knockdown/knockout RNA-Seq assay for LLGL2 is not available on ENCORE database.





108 RBPs can affect the gene expression of LLGL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LLGL2ENSG00000073350.91197.068501692.53310-0.4997010.100409.08860HepG2ACO1
LLGL2ENSG00000073350.92240.930801700.371900.398106.775905.63040HepG2AKAP8L
LLGL2ENSG00000073350.92898.963902167.088700.419708.055206.98310HepG2AUH
LLGL2ENSG00000073350.91962.886001692.029200.214102.740502.07760HepG2CKAP4
LLGL2ENSG00000073350.9665.60020412.787200.689208.364106.61210HepG2YBX3
LLGL2ENSG00000073350.91016.83450676.453400.587908.450907.44400HepG2CELF1
LLGL2ENSG00000073350.91040.55580727.378000.516508.183707.01200HepG2DAZAP1
LLGL2ENSG00000073350.91022.36470650.811900.651502.649701.98420HepG2DDX21
LLGL2ENSG00000073350.92411.067001327.215400.861202.634602.03150HepG2DDX6
LLGL2ENSG00000073350.91853.715201619.260300.195001.885101.30940HepG2DKC1
LLGL2ENSG00000073350.9920.36490405.297101.1831016.6400015.05680HepG2DNAJC21
LLGL2ENSG00000073350.9929.04950401.760401.2093020.8400019.20430HepG2DNAJC2
LLGL2ENSG00000073350.92947.467401274.794501.209106.817505.91460HepG2EIF2S1
LLGL2ENSG00000073350.91084.04010687.401300.657107.037605.76230HepG2EIF4G2
LLGL2ENSG00000073350.93385.847102488.279400.444307.544206.63330HepG2ETF1
LLGL2ENSG00000073350.92112.945201318.720800.680002.370701.75180HepG2G3BP1
LLGL2ENSG00000073350.91793.58880958.848600.903404.578803.76740HepG2GPKOW
LLGL2ENSG00000073350.91634.43540820.452800.994204.098702.41060HepG2HNRNPA0
LLGL2ENSG00000073350.9814.22570409.180400.992602.180601.60120HepG2HNRNPA1
LLGL2ENSG00000073350.91441.65330824.023600.8069018.9659017.31190HepG2HNRNPF
LLGL2ENSG00000073350.91099.60980662.593100.730705.320104.41170HepG2HNRNPL
LLGL2ENSG00000073350.91508.72100915.058100.721302.617502.00220HepG2HNRNPLL
LLGL2ENSG00000073350.91203.30770452.141301.4121023.0747021.45380HepG2HNRNPU
LLGL2ENSG00000073350.91334.15320811.426400.717305.352204.37730HepG2IGF2BP1
LLGL2ENSG00000073350.9766.08350461.845000.7300012.7984011.34900HepG2ILF2
LLGL2ENSG00000073350.91774.23210924.294300.940703.341402.00570HepG2KHDRBS1
LLGL2ENSG00000073350.92448.011001422.985000.782602.852302.18750HepG2MAGOH
LLGL2ENSG00000073350.92798.522501464.179600.934504.859704.03310HepG2NCBP2
LLGL2ENSG00000073350.91532.67770721.265201.0874014.2455012.57590HepG2NOL12
LLGL2ENSG00000073350.9774.83660333.151601.217604.908003.02340HepG2NOLC1
LLGL2ENSG00000073350.91659.71590655.323001.340605.593004.00650HepG2NONO
LLGL2ENSG00000073350.92028.66160885.388501.196005.407804.13490HepG2PABPC1
LLGL2ENSG00000073350.91048.22880403.271501.3780036.8607034.45140HepG2PPIL4
LLGL2ENSG00000073350.9662.76740927.39130-0.484706.139305.03700HepG2PRPF4
LLGL2ENSG00000073350.91408.04540549.063401.358503.089702.23980HepG2PRPF8
LLGL2ENSG00000073350.92458.72340688.503901.8363065.8018063.38770HepG2PUF60
LLGL2ENSG00000073350.91460.95680730.869300.9991034.2282032.61510HepG2PUM1
LLGL2ENSG00000073350.91951.25430730.340401.417705.890704.92550HepG2PUM2
LLGL2ENSG00000073350.91308.184802079.70540-0.6688012.4487011.51080HepG2RBM22
LLGL2ENSG00000073350.91944.507801377.879900.496902.040201.45560HepG2RBM25
LLGL2ENSG00000073350.91123.92690581.729800.950002.546001.52940HepG2RCC2
LLGL2ENSG00000073350.91915.334101560.145600.295802.975602.41810HepG2NELFE
LLGL2ENSG00000073350.91542.33760660.538001.223306.830305.60920HepG2RPS2
LLGL2ENSG00000073350.91019.69110402.643601.340509.477308.39680HepG2SAFB2
LLGL2ENSG00000073350.92672.609701741.395900.617904.899403.98560HepG2SF3A3
LLGL2ENSG00000073350.91235.04960905.655100.447402.040601.42940HepG2SF3B1
LLGL2ENSG00000073350.91986.263201459.430000.444608.006507.08250HepG2SF3B4
LLGL2ENSG00000073350.91460.56790660.151501.1456039.1333037.15040HepG2SLBP
LLGL2ENSG00000073350.9945.76960469.536601.0102025.1043023.48220HepG2SMN1
LLGL2ENSG00000073350.91137.80370534.932101.088703.614302.50620HepG2SMNDC1
LLGL2ENSG00000073350.91643.74440679.787701.2737046.1238044.01910HepG2SRSF5
LLGL2ENSG00000073350.91312.55550809.581700.697003.548802.77440HepG2SRSF7
LLGL2ENSG00000073350.92811.412602039.279900.463109.817208.96560HepG2SSB
LLGL2ENSG00000073350.91979.14550847.779401.223006.663904.89620HepG2STIP1
LLGL2ENSG00000073350.91745.20300773.114201.1745046.6469044.64670HepG2SUCLG1
LLGL2ENSG00000073350.91320.04980709.364500.895901.963101.37860HepG2SUPV3L1
LLGL2ENSG00000073350.9569.757601369.48310-1.265209.674308.72780HepG2TAF15
LLGL2ENSG00000073350.91575.30410439.287201.8423028.6602027.36590HepG2TIAL1
LLGL2ENSG00000073350.91423.20160443.270601.6828028.6141027.04030HepG2TRIM56
LLGL2ENSG00000073350.91413.08580672.626101.070903.046702.12520HepG2TUFM
LLGL2ENSG00000073350.92369.85010711.955501.734807.354605.96510HepG2UBE2L3
LLGL2ENSG00000073350.9878.62920418.880801.068603.076502.27720HepG2UCHL5
LLGL2ENSG00000073350.92130.791501544.356300.464309.675908.50640HepG2UPF1
LLGL2ENSG00000073350.91162.784201491.00860-0.358704.679903.93300HepG2UTP3
LLGL2ENSG00000073350.91795.78330872.401001.041403.599402.34110HepG2XPO5
LLGL2ENSG00000073350.91153.35220915.213300.333604.153603.35540HepG2ZC3H8
LLGL2ENSG00000073350.92455.952601698.490100.5319015.8162014.77780HepG2ZNF622
LLGL2ENSG00000073350.9812.91420486.182300.7415011.3754010.31860K562AGGF1
LLGL2ENSG00000073350.9744.01390534.254500.477703.208702.13170K562AKAP8
LLGL2ENSG00000073350.9846.80340505.898100.743108.672407.44840K562AKAP8L
LLGL2ENSG00000073350.9439.73060580.04280-0.399501.854101.35550K562AQR
LLGL2ENSG00000073350.9683.84580530.815200.365403.000802.05110K562ATP5C1
LLGL2ENSG00000073350.9449.00610204.407601.1352014.2125012.00820K562BCLAF1
LLGL2ENSG00000073350.9249.45610161.561300.626603.158501.77990K562CIRBP
LLGL2ENSG00000073350.9200.40330124.108000.691203.094702.26510K562CPSF6
LLGL2ENSG00000073350.9351.30060155.073701.1797010.994908.72000K562CSTF2
LLGL2ENSG00000073350.9768.96040570.425200.430803.226701.64060K562DDX19B
LLGL2ENSG00000073350.9595.84130433.791700.457804.080002.59140K562DDX21
LLGL2ENSG00000073350.9269.04910179.186500.586303.548502.02740K562DDX27
LLGL2ENSG00000073350.9517.38870387.929500.415402.821701.76990K562DDX3X
LLGL2ENSG00000073350.9555.76010393.316300.498703.125401.71330K562DDX6
LLGL2ENSG00000073350.9703.74320544.361500.370403.258202.29760K562DKC1
LLGL2ENSG00000073350.9329.41880159.946001.042204.500803.31980K562EFTUD2
LLGL2ENSG00000073350.9508.56000309.799800.715007.397806.30410K562EIF2S2
LLGL2ENSG00000073350.9190.18660107.040200.829203.805802.71920K562FTO
LLGL2ENSG00000073350.9260.46540421.49890-0.694405.977505.13780K562FXR1
LLGL2ENSG00000073350.917.7143050.60430-1.514303.250502.47370K562G3BP2
LLGL2ENSG00000073350.9225.32280118.489700.927104.673103.64490K562GPKOW
LLGL2ENSG00000073350.9572.56780412.824200.471803.162202.35690K562GRSF1
LLGL2ENSG00000073350.9361.39560263.105500.457802.018801.49830K562HNRNPC
LLGL2ENSG00000073350.9266.73270153.416400.797803.707502.28580K562IGF2BP3
LLGL2ENSG00000073350.9343.03390234.871400.546402.929301.35560K562LSM11
LLGL2ENSG00000073350.9288.87950158.430100.866506.424305.11770K562MAGOH
LLGL2ENSG00000073350.9673.04580513.928700.389002.356601.39160K562MAK16
LLGL2ENSG00000073350.9228.41760158.085700.530902.548001.66610K562MATR3
LLGL2ENSG00000073350.9913.52800601.434500.602906.869605.31160K562MBNL1
LLGL2ENSG00000073350.9231.68700115.660401.002206.037904.71760K562METAP2
LLGL2ENSG00000073350.9656.37230498.863000.395803.918403.04930K562NSUN2
LLGL2ENSG00000073350.9231.96100154.936400.582102.809801.45060K562PCBP1
LLGL2ENSG00000073350.9231.15760140.935900.713702.634801.68080K562PCBP2
LLGL2ENSG00000073350.9342.22960235.212000.540903.160002.27450K562PPIG
LLGL2ENSG00000073350.9341.03780235.933600.531502.799401.88870K562PSIP1
LLGL2ENSG00000073350.9281.82650153.936100.872406.575005.58550K562PTBP1
LLGL2ENSG00000073350.9561.49210777.88760-0.470303.241802.08310K562PUM1
LLGL2ENSG00000073350.9779.72180501.688100.636103.151602.57890K562PUS1
LLGL2ENSG00000073350.9714.42410488.839400.547305.663304.83980K562RBM15
LLGL2ENSG00000073350.9249.21100147.523600.756303.932602.91620K562RBM22
LLGL2ENSG00000073350.9126.8492052.632301.269006.368205.03440K562SF3B4
LLGL2ENSG00000073350.9333.04400204.189600.705704.247602.89740K562SRFBP1
LLGL2ENSG00000073350.9261.64860150.925700.793704.736603.81580K562SRSF1
LLGL2ENSG00000073350.9264.66860154.673000.774904.137902.81430K562SRSF4
LLGL2ENSG00000073350.9325.38060142.580001.1903010.793908.56290K562SRSF5
LLGL2ENSG00000073350.9172.24590298.09910-0.791304.047103.04880K562SYNCRIP
LLGL2ENSG00000073350.9354.67210152.710001.215606.030404.95750K562TARDBP
LLGL2ENSG00000073350.9370.78850147.315701.331605.514404.29510K562TIA1
LLGL2ENSG00000073350.9354.65640144.647201.2938012.512809.61330K562TRA2A
LLGL2ENSG00000073350.9351.16880241.234300.541602.709401.77470K562TRIM56
LLGL2ENSG00000073350.923.7986050.67010-1.090302.268801.54240K562U2AF2
LLGL2ENSG00000073350.9314.70740159.404000.981202.958001.89740K562UCHL5
LLGL2ENSG00000073350.9337.42160162.453101.054403.610802.16340K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LLGL2 is not available on ENCORE database.





12 RBPs can affect the splicing of LLGL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELLGL2ENSG00000073350.9chr17+7354725073547485735394777353958273552126735522240.084000.000550.01240includedHepG2U2AF1
SELLGL2ENSG00000073350.9chr17+735677477356786473567030735671817356797873568145-0.078000.000630.01389excludedHepG2U2AF1
SELLGL2ENSG00000073350.9chr17+7354725073547485735394777353958273552126735522240.103000.001390.05726includedHepG2SFPQ
SELLGL2ENSG00000073350.9chr17+735705337357057673570234735703417357069073570749-0.216000.001630.06981excludedHepG2PCBP1
A5SSLLGL2ENSG00000073350.9chr17+7356043373560605735604337356058873564556735647740.217000.000050.01999longerHepG2FUBP3
A5SSLLGL2ENSG00000073350.9chr17+7356043373560605735604337356058873564556735647740.200000.000010.00231longerHepG2SF3B4
A5SSLLGL2ENSG00000073350.9chr17+7356043373560605735604337356058873564556735647740.239000.000100.02066longerHepG2AKAP1
A5SSLLGL2ENSG00000073350.9chr17+7356043373560605735604337356058873564556735647740.224000.000110.01860longerHepG2QKI
A5SSLLGL2ENSG00000073350.9chr17+7356043373560609735604337356058873564556735647740.267000.000110.01363longerHepG2U2AF1
RILLGL2ENSG00000073350.9chr17+7357053373570749735705337357057673570690735707490.056000.005560.03699includedHepG2U2AF2
RILLGL2ENSG00000073350.9chr17+7357029373570749735702937357034173570533735707490.166000.000200.00418includedHepG2PCBP1
RILLGL2ENSG00000073350.9chr17+7357053373570749735705337357057673570690735707490.178000.000020.00069includedHepG2PCBP1
RILLGL2ENSG00000073350.9chr17+7357029373570749735702937357034173570533735707490.217000.000280.00425includedHepG2TAF15
RILLGL2ENSG00000073350.9chr17+7357029373570749735702937357034173570533735707490.133000.002100.01731includedHepG2SF3B4
RILLGL2ENSG00000073350.9chr17+7357053373570749735705337357057673570690735707490.116000.000650.00883includedHepG2RBM22
RILLGL2ENSG00000073350.9chr17+7357029373570749735702937357034173570533735707490.147000.001120.02032includedHepG2SRSF9
RILLGL2ENSG00000073350.9chr17+735702937357074973570293735703417357069073570749-0.194000.001480.06636excludedHepG2LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LLGL2 is not avaliable on ENCORE database.