SIM2

General Information

Gene Name       : SIM2
Gene ID             : ENSG00000159263.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SIM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIM2ENSG00000159263.150.000.000.00ENCSR000AEF
HepG2SIM2ENSG00000159263.151.580.811.20ENCSR985KAT
K562SIM2ENSG00000159263.150.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIM2 RNA is bound by 8 proteins.  







eCLIP assay for SIM2 is not avaliable on ENCORE database.





8 proteins are bound to SIM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr213812007938120106+CDS3.856813.79118HepG2TROVE2
chr213812009438120105+CDS4.0651418.33824K562RPS3
chr213812009238120104+CDS11.30409110.30539K562UTP3
chr213812007838120104+CDS5.102234.63925K562PHF6
chr213812008238120092+CDS11.30409110.30539K562UTP3
chr213812009438120104+CDS3.203944.09315K562EXOSC5
chr213812007938120104+CDS6.001038.91709K562DDX24
chr213812007938120104+CDS5.474075.03841K562AATF
chr213812008238120094+CDS4.0651418.33824K562RPS3
chr213812008138120094+CDS3.203944.09315K562EXOSC5
chr213812007938120104+CDS5.825737.89887K562DDX51
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIM2 is not available on ENCORE database.

  • 25 RBPs can affect the levels of SIM2.  








The Knockdown/knockout RNA-Seq assay for SIM2 is not available on ENCORE database.





25 RBPs can affect the gene expression of SIM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIM2ENSG00000159263.1162.2515030.040901.051101.903801.45270HepG2AKAP1
SIM2ENSG00000159263.1168.9295024.853701.471603.852202.93100HepG2ASCC1
SIM2ENSG00000159263.1161.7529016.326801.919205.937805.03070HepG2CKAP4
SIM2ENSG00000159263.1145.4628015.104901.589603.921802.94970HepG2DDX19B
SIM2ENSG00000159263.1155.6610025.958701.100302.766002.11450HepG2DNAJC2
SIM2ENSG00000159263.11111.7921025.570102.128208.163107.01130HepG2EIF4B
SIM2ENSG00000159263.1197.1760047.498401.032603.598002.92630HepG2ETF1
SIM2ENSG00000159263.1140.5331015.958001.344702.445601.66040HepG2EWSR1
SIM2ENSG00000159263.1157.6490024.576601.229902.708902.05010HepG2G3BP1
SIM2ENSG00000159263.11103.5676026.658801.957807.278806.29190HepG2MATR3
SIM2ENSG00000159263.1161.2402024.287001.334203.196402.42170HepG2PABPC4
SIM2ENSG00000159263.1190.1015026.318601.775405.915405.17640HepG2PTBP1
SIM2ENSG00000159263.11108.4978040.212401.431905.678404.73020HepG2PUM2
SIM2ENSG00000159263.1159.5657016.636601.840005.424204.61410HepG2PUS1
SIM2ENSG00000159263.1194.6314039.700601.253104.420303.80530HepG2RBM22
SIM2ENSG00000159263.1175.2373028.282101.411504.012003.28590HepG2RPS19
SIM2ENSG00000159263.1154.3519026.021301.062502.366001.76340HepG2SAFB2
SIM2ENSG00000159263.1176.5399031.570701.277503.523002.73630HepG2SF3B1
SIM2ENSG00000159263.1167.8979027.400501.309103.382102.73660HepG2SF3B4
SIM2ENSG00000159263.1194.0743044.841601.068903.638103.08750HepG2SRFBP1
SIM2ENSG00000159263.1145.8754023.268100.979301.882301.41100HepG2SRSF9
SIM2ENSG00000159263.1177.9653029.800001.387404.173702.62140HepG2SSRP1
SIM2ENSG00000159263.1193.7990042.567701.139703.795603.08820HepG2SUCLG1
SIM2ENSG00000159263.1164.8222031.092901.059802.368801.69050HepG2TARDBP
SIM2ENSG00000159263.1161.1745031.064300.977602.275701.31180HepG2UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIM2 is not available on ENCORE database.






No RBPs affect the alternative splcing events of SIM2 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for SIM2 is not avaliable on ENCORE database.