MECR

General Information

Gene Name       : MECR
Gene ID             : ENSG00000116353.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MECR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MECRENSG00000116353.1514.4128.2121.31ENCSR000AEF
HepG2MECRENSG00000116353.1519.1218.3318.73ENCSR985KAT
K562MECRENSG00000116353.1542.0935.5238.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MECR is not avaliable on ENCORE database.



Proteins bound to RNA
  • MECR RNA is bound by 9 proteins.  







eCLIP assay for MECR is not avaliable on ENCORE database.





9 proteins are bound to MECR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12952054029520597-3'-UTR,CDS,intron-Distal,intron-Proximal4.297084.48994K562RBM15
chr12952241929522477-3'-UTR,CDS,intron-Distal,intron-Proximal5.580484.68690HepG2PRPF8
chr12952038829520549-3'-UTR,CDS,intron-Distal,intron-Proximal4.620929.59522K562PABPC4
chr12952045129520521-3'-UTR,intron-Distal,intron-Proximal3.849623.15006K562RBM15
chr12952240429522500-3'-UTR,CDS,intron-Distal,intron-Proximal4.5397615.03023K562PRPF8
chr12955728229557439-5'-UTR,CDS,intron-Distal,intron-Proximal3.693947.42472HepG2NCBP2
chr12955735529557430-5'-UTR,CDS,intron-Distal,intron-Proximal4.582384.66602K562DDX3X
chr12954310929543197-5'-UTR,CDS,intron-Distal,intron-Proximal3.269644.00731K562UCHL5
chr12954249229542573-CDS,intron-Distal,intron-Proximal4.318085.64484HepG2PRPF8
chr12952697829527098-CDS,intron-Distal,intron-Proximal3.549509.74175K562PRPF8
chr12952698429527061-CDS,intron-Distal,intron-Proximal4.7671415.73783HepG2PRPF8
chr12952840329528465-CDS,intron-Distal,intron-Proximal3.879748.46423K562PRPF8
chr12954254129542654-CDS,intron-Distal,intron-Proximal3.240683.75245K562BUD13
chr12954252829542617-CDS,intron-Distal,intron-Proximal3.469143.87469HepG2BCLAF1
chr12952241029522434-intron-Distal,intron-Proximal3.360593.93631K562AQR
chr12952688829526978-intron-Distal,intron-Proximal3.348956.40795K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MECR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MECR is not available on ENCORE database.

  • 38 RBPs can affect the levels of MECR.  








The Knockdown/knockout RNA-Seq assay for MECR is not available on ENCORE database.





38 RBPs can affect the gene expression of MECR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MECRENSG00000116353.1176.98810162.03950-1.073605.241403.93450HepG2ADAR
MECRENSG00000116353.11196.16660121.802000.687402.903902.29200HepG2BOP1
MECRENSG00000116353.11144.20340246.90170-0.775803.853003.16030HepG2EIF2S1
MECRENSG00000116353.11202.93280275.27430-0.439902.065101.43960HepG2HNRNPF
MECRENSG00000116353.11163.55470258.80010-0.662103.151902.40720HepG2HNRNPK
MECRENSG00000116353.1172.46670148.97490-1.039703.437702.44100HepG2PABPC1
MECRENSG00000116353.11161.10030287.41340-0.835205.253804.46520HepG2PUF60
MECRENSG00000116353.1189.27480163.75210-0.875202.718302.01960HepG2RAVER1
MECRENSG00000116353.11108.17270172.51220-0.673402.306801.69080HepG2SF3A3
MECRENSG00000116353.1154.96860119.71560-1.122904.071003.23000HepG2SF3B1
MECRENSG00000116353.11223.37910330.70850-0.566103.900803.31490HepG2SSB
MECRENSG00000116353.11559.72140431.751600.374402.898901.35550K562AKAP1
MECRENSG00000116353.11469.33630874.16930-0.8973010.683809.64220K562AQR
MECRENSG00000116353.11232.44540517.78050-1.1554012.8825010.73790K562EFTUD2
MECRENSG00000116353.11513.33390646.29080-0.332302.479701.79210K562EIF2S2
MECRENSG00000116353.11268.08570554.34390-1.048109.741707.64440K562EIF3D
MECRENSG00000116353.11502.10300376.700200.414502.501901.69650K562FIP1L1
MECRENSG00000116353.11117.44580295.98310-1.333509.587608.11620K562G3BP2
MECRENSG00000116353.11554.53580720.53430-0.377802.851101.76240K562HNRNPA1
MECRENSG00000116353.11257.70040486.08980-0.915508.871107.85280K562HNRNPC
MECRENSG00000116353.11317.39190434.17040-0.452002.546301.45780K562HNRNPF
MECRENSG00000116353.11287.55200459.62760-0.676604.650603.01290K562HNRNPK
MECRENSG00000116353.11531.40400797.90560-0.586407.017605.59230K562HNRNPU
MECRENSG00000116353.11674.26680510.681100.400802.585801.81480K562HSPD1
MECRENSG00000116353.11311.27540470.98830-0.597504.422002.60510K562LARP7
MECRENSG00000116353.11191.60710430.35290-1.1674010.430808.47840K562PCBP2
MECRENSG00000116353.11624.21690427.675000.545404.264703.21470K562PPIG
MECRENSG00000116353.11244.17330503.86110-1.045109.892808.46940K562PRPF8
MECRENSG00000116353.11653.447601130.29170-0.790605.362804.22980K562PUF60
MECRENSG00000116353.11276.87550606.38350-1.131005.300102.98570K562RBM39
MECRENSG00000116353.11633.57700474.132700.418102.499701.46830K562NELFE
MECRENSG00000116353.11380.04370588.93590-0.631906.759105.53220K562SF3A3
MECRENSG00000116353.11136.35420228.15280-0.742603.217002.16600K562SF3B1
MECRENSG00000116353.11216.30940307.99940-0.509802.937202.05480K562SF3B4
MECRENSG00000116353.11234.10950517.60800-1.144705.594503.63920K562SNRNP200
MECRENSG00000116353.11593.10150460.795700.364102.303001.65040K562SRSF1
MECRENSG00000116353.11353.24380487.79170-0.465602.478201.52200K562SUPV3L1
MECRENSG00000116353.11173.48360290.56160-0.744002.807301.33260K562TAF15
MECRENSG00000116353.11148.30290287.16140-0.953305.883004.15710K562U2AF1
MECRENSG00000116353.11130.44330296.49100-1.1846010.716309.12870K562U2AF2
MECRENSG00000116353.11344.68760516.29490-0.582903.995102.74880K562UCHL5
MECRENSG00000116353.11457.88940563.09380-0.298402.147601.39490K562WDR43
MECRENSG00000116353.11633.48260984.83670-0.636607.226805.71700K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MECR is not available on ENCORE database.





17 RBPs can affect the splicing of MECR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMECRENSG00000116353.11chr1-2954734929547433295430992954319729557242295574090.117000.005310.07730includedK562SF3B4
SEMECRENSG00000116353.11chr1-2954734929547433295430992954319729557242295574090.109000.000040.02162includedK562PUM1
SEMECRENSG00000116353.11chr1-2952788529528030295270272952710129528454295285570.089000.000320.00465includedK562AQR
SEMECRENSG00000116353.11chr1-2952788529528030295270272952710129528454295285570.090000.001610.05724includedK562FXR1
SEMECRENSG00000116353.11chr1-2954734929547433295430992954319729557242295574090.111000.000060.01907includedK562APOBEC3C
SEMECRENSG00000116353.11chr1-2954734929547433295430992954319729557242295574090.138000.000020.00278includedK562HNRNPL
SEMECRENSG00000116353.11chr1-295473492954743329543099295433242955724229557409-0.249000.000820.05674excludedK562HNRNPUL1
SEMECRENSG00000116353.11chr1-2954734929547433295430992954319729557242295574090.357000.000000.00011includedK562U2AF2
SEMECRENSG00000116353.11chr1-295296422952974529528454295285572953327329533340-0.222000.002910.04713excludedK562U2AF2
SEMECRENSG00000116353.11chr1-295296422952974529528454295285572953327329533340-0.104000.000660.02732excludedK562HNRNPU
SEMECRENSG00000116353.11chr1-295296422952974529528454295285572953327329533340-0.436000.000400.01996excludedK562SF3B1
SEMECRENSG00000116353.11chr1-295296422952974529528454295285572953327329533340-0.173000.000430.02404excludedK562HNRNPK
SEMECRENSG00000116353.11chr1-295296422952974529528454295285572953327329533340-0.198000.001910.03271excludedK562HNRNPC
A3SSMECRENSG00000116353.11chr1-2952245229522567295224522952252529522709295227700.106000.006040.03411longerK562AQR
A3SSMECRENSG00000116353.11chr1-2952054329520736295205432952069129522452295225670.058000.001920.01238longerK562AQR
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.200000.000540.04661includedK562HNRNPU
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.466000.011100.06561includedHepG2U2AF2
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.275000.011600.09878includedHepG2PRPF8
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.172000.001600.02277includedHepG2PCBP1
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.146000.002810.03146includedHepG2QKI
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.296000.002970.04024includedK562U2AF2
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.178000.002130.01752includedHepG2SF3B4
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.397000.000000.00001includedK562EFTUD2
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.133000.000290.04906includedK562HNRNPA1
RIMECRENSG00000116353.11chr1-2952245229522770295224522952252529522709295227700.255000.002600.01596includedK562AQR
MXEMECRENSG00000116353.11chr1-29529642295297452953327329533457295284542952855729542516295426480.072000.015590.090331includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MECR is not avaliable on ENCORE database.