CYCS

General Information

Gene Name       : CYCS
Gene ID             : ENSG00000172115.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CYCS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CYCSENSG00000172115.8305.95323.28314.62ENCSR000AEF
HepG2CYCSENSG00000172115.876.52157.60117.06ENCSR985KAT
K562CYCSENSG00000172115.8503.64517.97510.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CYCS is not avaliable on ENCORE database.



Proteins bound to RNA
  • CYCS RNA is bound by 22 proteins.  







eCLIP assay for CYCS is not avaliable on ENCORE database.





22 proteins are bound to CYCS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr72516275825162821-3'-UTR,intron-Distal3.5305510.29289K562UPF1
chr72516291625162973-3'-UTR,intron-Distal,intron-Proximal4.304478.55824K562IGF2BP1
chr72516308925163131-3'-UTR,intron-Distal3.677215.63408HepG2SUB1
chr72516285125162909-3'-UTR,intron-Distal,intron-Proximal4.5105417.38406K562UPF1
chr72516269825162736-3'-UTR,intron-Distal4.925967.36168HepG2SUB1
chr72516291225162934-3'-UTR,intron-Distal,intron-Proximal3.4270512.86265K562UPF1
chr72516286625162906-3'-UTR,intron-Distal,intron-Proximal3.291224.39435HepG2SUB1
chr72516293425162987-3'-UTR,intron-Distal,intron-Proximal3.0690224.70065K562UPF1
chr72516249625162525-3'-UTR,intron-Distal3.121374.79983K562UPF1
chr72516291325162984-3'-UTR,intron-Distal,intron-Proximal3.0121714.13973K562FAM120A
chr72516372625163746-3'-UTR,5'-UTR,CDS,intron-Distal3.9474224.73760K562DDX3X
chr72516292725162966-3'-UTR,intron-Distal,intron-Proximal4.530259.44359HepG2SUB1
chr72516473125164814-5'-UTR,intron-Distal3.493804.34492K562XRN2
chr72516474325164799-5'-UTR,intron-Distal4.502465.52476K562BUD13
chr72516457725164649-5'-UTR,intron-Distal4.522016.01740K562SRSF1
chr72516477125164822-5'-UTR,intron-Distal3.976194.45914HepG2PRPF8
chr72516477625164819-5'-UTR,intron-Distal4.502794.59919HepG2AQR
chr72516483025164881-5'-UTR,intron-Distal,intron-Proximal3.5225118.63759K562RPS3
chr72516481725164895-5'-UTR,intron-Distal,intron-Proximal4.10936400.00000K562DDX3X
chr72516481225164819-5'-UTR,intron-Distal4.3164413.54022K562AQR
chr72516475825164788-5'-UTR,intron-Distal6.3395516.13178K562AQR
chr72516480225164876-5'-UTR,intron-Distal,intron-Proximal3.666195.89909HepG2NCBP2
chr72516481725164885-5'-UTR,intron-Distal,intron-Proximal3.281234.67270K562EIF3G
chr72516478825164812-5'-UTR,intron-Distal5.3395514.99196K562AQR
chr72516481325164883-5'-UTR,intron-Distal,intron-Proximal4.0665111.50386K562NOLC1
chr72516336225163439-CDS,intron-Distal3.7264632.90073K562UCHL5
chr72516357825163654-CDS,intron-Distal3.7267330.45312K562UCHL5
chr72516333825163443-CDS,intron-Distal3.2180534.90707K562ZNF622
chr72516334025163381-CDS,intron-Distal4.8502917.76325K562GRWD1
chr72516334425163393-CDS,intron-Distal3.4778812.54826K562PUM1
chr72516341925163437-CDS,intron-Distal5.5940110.73333K562GRWD1
chr72516357525163639-CDS,intron-Distal3.0676019.85483K562ZNF800
chr72516356925163579-CDS,intron-Distal,intron-Proximal3.680463.46619K562GRWD1
chr72516366025163684-CDS,intron-Distal3.2084713.72570K562ZNF800
chr72516333125163362-CDS,intron-Distal,intron-Proximal3.5172317.61658K562UCHL5
chr72516358025163600-CDS,intron-Distal3.1405112.20084K562YBX3
chr72516344725163468-CDS,intron-Distal3.7129011.93078K562YBX3
chr72516344125163447-CDS,intron-Distal3.661853.02250K562YBX3
chr72516368425163706-CDS,intron-Distal3.8525511.82728K562ZNF800
chr72516365425163704-CDS,intron-Distal3.2727520.58408K562UCHL5
chr72516334425163392-CDS,intron-Distal3.956933.45275HepG2LARP4
chr72516356825163580-CDS,intron-Distal,intron-Proximal3.4710811.57427K562YBX3
chr72516333525163434-CDS,intron-Distal4.4462417.22692HepG2BCLAF1
chr72516338125163393-CDS,intron-Distal5.2764215.37841K562GRWD1
chr72516334225163441-CDS,intron-Distal3.854414.65332HepG2ZNF800
chr72516363725163699-CDS,intron-Distal3.580345.97823HepG2BCLAF1
chr72516343725163468-CDS,intron-Distal4.360797.28917K562GRWD1
chr72516358125163666-CDS,intron-Distal4.0830139.16632K562RPS3
chr72516336525163433-CDS,intron-Distal3.4470014.31592K562ZNF800
chr72516339325163419-CDS,intron-Distal5.1558414.46983K562GRWD1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CYCS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CYCS is not available on ENCORE database.

  • 129 RBPs can affect the levels of CYCS.  








The Knockdown/knockout RNA-Seq assay for CYCS is not available on ENCORE database.





129 RBPs can affect the gene expression of CYCS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYCSENSG00000172115.41097.469101559.16890-0.506603.689402.55690HepG2ADAR
CYCSENSG00000172115.44517.433003441.326100.392402.964002.41570HepG2AKAP1
CYCSENSG00000172115.41966.064301529.695800.362003.537401.95940HepG2ATP5C1
CYCSENSG00000172115.42569.958303339.25070-0.377802.574401.90900HepG2AUH
CYCSENSG00000172115.42150.873401592.460600.433604.988503.98970HepG2CALR
CYCSENSG00000172115.41302.737302230.32310-0.775702.267401.39360HepG2CCAR1
CYCSENSG00000172115.4873.353601861.27570-1.0917020.2634018.62030HepG2CPSF6
CYCSENSG00000172115.41458.406201922.21530-0.398407.666106.39370HepG2DDX19B
CYCSENSG00000172115.41039.515501514.32150-0.542802.727401.74890HepG2DHX30
CYCSENSG00000172115.4786.476301570.12490-0.9974011.096809.76420HepG2DNAJC21
CYCSENSG00000172115.41125.744501555.99180-0.467003.981103.22700HepG2DNAJC2
CYCSENSG00000172115.41348.468001066.040500.339002.453301.40860HepG2EFTUD2
CYCSENSG00000172115.42033.814302722.38650-0.420703.636702.96190HepG2EIF2S1
CYCSENSG00000172115.41315.613801038.027700.341802.409501.56150HepG2EIF3D
CYCSENSG00000172115.41772.279803008.70860-0.763509.090007.93790HepG2EIF4A3
CYCSENSG00000172115.44167.990202929.111000.508803.713702.92280HepG2EIF4B
CYCSENSG00000172115.42456.833503833.66660-0.641907.403806.49980HepG2ETF1
CYCSENSG00000172115.4594.855001095.89480-0.8815013.1875011.52990HepG2FUBP3
CYCSENSG00000172115.42266.900603035.20260-0.421103.810303.00880HepG2FXR1
CYCSENSG00000172115.42045.564902815.83650-0.461103.916903.13200HepG2G3BP1
CYCSENSG00000172115.41912.624702989.05640-0.644108.116406.57350HepG2G3BP2
CYCSENSG00000172115.41437.348701984.25980-0.465208.781807.16360HepG2HDGF
CYCSENSG00000172115.41049.309801763.11290-0.748706.592905.55960HepG2HNRNPC
CYCSENSG00000172115.41461.923802234.17780-0.6119014.4971013.02960HepG2HNRNPF
CYCSENSG00000172115.42132.086202910.38940-0.4489012.5709011.22940HepG2HNRNPL
CYCSENSG00000172115.41241.598801751.46290-0.496403.446702.77750HepG2HNRNPU
CYCSENSG00000172115.41485.499402200.02810-0.566608.913407.68470HepG2IGF2BP1
CYCSENSG00000172115.41921.148902862.32210-0.575206.370605.38360HepG2IGF2BP2
CYCSENSG00000172115.41104.730001789.07660-0.695506.660505.57270HepG2ILF2
CYCSENSG00000172115.42035.225001552.841500.390203.908601.97590HepG2CCAR2
CYCSENSG00000172115.41342.996701899.89860-0.5005011.872809.92470HepG2KIF1C
CYCSENSG00000172115.41275.176602053.43930-0.687305.150303.80020HepG2MTPAP
CYCSENSG00000172115.42305.166903168.09790-0.458705.979704.86110HepG2NOL12
CYCSENSG00000172115.41039.931902783.57250-1.4204025.8253023.70110HepG2PABPC4
CYCSENSG00000172115.41196.390001733.75990-0.535204.614803.55360HepG2PARN
CYCSENSG00000172115.42253.889502612.68050-0.213102.526501.93960HepG2PCBP1
CYCSENSG00000172115.4654.87360858.41030-0.390502.509201.34240HepG2PKM
CYCSENSG00000172115.4864.255101562.18050-0.854009.215407.91620HepG2PPIL4
CYCSENSG00000172115.41012.391701265.22700-0.321603.507302.64680HepG2PRPF4
CYCSENSG00000172115.42787.745203210.27670-0.203603.481302.83120HepG2PUM1
CYCSENSG00000172115.42306.491703207.95580-0.476007.742106.64560HepG2PUM2
CYCSENSG00000172115.42348.202602879.20210-0.294103.454102.76680HepG2QKI
CYCSENSG00000172115.42565.394901819.211500.495802.503401.83150HepG2RAVER1
CYCSENSG00000172115.41097.310001883.65090-0.7796015.8772014.09710HepG2RBM15
CYCSENSG00000172115.42614.923702958.66050-0.178201.899601.43230HepG2NELFE
CYCSENSG00000172115.41766.854202755.61770-0.6412017.6275016.28910HepG2RECQL
CYCSENSG00000172115.4698.747201009.98170-0.531505.208804.39590HepG2RPS19
CYCSENSG00000172115.41541.871902068.81350-0.424102.037901.35160HepG2RPS3A
CYCSENSG00000172115.41195.174301559.80760-0.384102.837302.18680HepG2SAFB2
CYCSENSG00000172115.4658.906401883.89680-1.515606.455804.24370HepG2SF1
CYCSENSG00000172115.4658.840201993.07980-1.5970042.5864040.24950HepG2SF3B1
CYCSENSG00000172115.42404.912302899.65120-0.269904.870303.97970HepG2SLBP
CYCSENSG00000172115.4738.998401774.79950-1.264007.986105.49330HepG2SLTM
CYCSENSG00000172115.44775.064902889.026600.7248025.0354023.92390HepG2SRSF1
CYCSENSG00000172115.42525.733302985.90460-0.241503.349002.67170HepG2SRSF5
CYCSENSG00000172115.41654.879902195.00340-0.407507.127106.09330HepG2SRSF7
CYCSENSG00000172115.41691.349802350.38850-0.4747010.422309.47020HepG2SRSF9
CYCSENSG00000172115.4849.848901197.65560-0.494903.558402.11870HepG2SSRP1
CYCSENSG00000172115.42698.872903395.83580-0.331407.126206.20800HepG2SUCLG1
CYCSENSG00000172115.41819.733702617.40180-0.524402.686602.01890HepG2SUPV3L1
CYCSENSG00000172115.41286.843301702.20760-0.403601.849101.42240HepG2TIAL1
CYCSENSG00000172115.41254.615601717.06540-0.452703.625002.99810HepG2TRIM56
CYCSENSG00000172115.42277.856902954.44620-0.375204.485203.34150HepG2TUFM
CYCSENSG00000172115.42511.079503127.19340-0.316602.138001.40830HepG2UBE2L3
CYCSENSG00000172115.42694.080002000.565300.429302.554001.53950HepG2XRCC6
CYCSENSG00000172115.41639.423302576.53720-0.652203.895803.04440HepG2XRN2
CYCSENSG00000172115.49833.4874012433.58850-0.338503.341201.98250K562ABCF1
CYCSENSG00000172115.48302.867306774.287100.293405.921605.14070K562AGGF1
CYCSENSG00000172115.49561.017407048.882300.439705.770604.80660K562AKAP8L
CYCSENSG00000172115.413433.0188020285.20710-0.594606.027605.21880K562AQR
CYCSENSG00000172115.49233.9586011298.74670-0.291102.666101.38520K562BCCIP
CYCSENSG00000172115.48608.0500010917.95740-0.342908.526306.80870K562BCLAF1
CYCSENSG00000172115.44528.734307787.10420-0.782006.126904.81720K562BOP1
CYCSENSG00000172115.41858.139503406.30660-0.8743015.9367012.84260K562CCAR1
CYCSENSG00000172115.46853.8194012305.98840-0.844405.971304.35350K562CNOT7
CYCSENSG00000172115.49287.4234011498.28710-0.308103.519202.26340K562CPEB4
CYCSENSG00000172115.43637.573908280.24490-1.1867015.4928013.60300K562CPSF6
CYCSENSG00000172115.45115.740908282.89580-0.6952021.6456018.53610K562CSTF2
CYCSENSG00000172115.45867.366207678.94650-0.388208.161706.06840K562DDX21
CYCSENSG00000172115.47895.333609574.19170-0.278204.778203.02810K562DDX27
CYCSENSG00000172115.42574.355603813.16950-0.566806.878704.66260K562DHX30
CYCSENSG00000172115.410135.826407585.544500.418008.876307.13580K562DKC1
CYCSENSG00000172115.45809.754107853.30980-0.434802.156401.35050K562EFTUD2
CYCSENSG00000172115.46118.296107691.54700-0.330106.489704.60740K562EIF2S1
CYCSENSG00000172115.46512.7057012000.72810-0.8818028.2454026.37290K562EIF2S2
CYCSENSG00000172115.44894.213707315.73150-0.579909.296407.78940K562EIF4A3
CYCSENSG00000172115.44750.784406588.25140-0.471706.675904.75660K562EIF4B
CYCSENSG00000172115.414341.9814018685.14850-0.381608.122506.53430K562EIF4G2
CYCSENSG00000172115.45403.954506385.91350-0.240902.692101.42240K562EWSR1
CYCSENSG00000172115.44441.341106182.50440-0.477207.502505.37480K562EXOSC5
CYCSENSG00000172115.47462.200609732.35530-0.383203.710001.83550K562FASTKD2
CYCSENSG00000172115.45205.903408424.33530-0.694407.602006.14550K562FMR1
CYCSENSG00000172115.44436.204807140.11600-0.686606.992305.46960K562FTO
CYCSENSG00000172115.410238.434007608.059800.428307.180306.26860K562FXR1
CYCSENSG00000172115.46895.873508001.29390-0.214502.580001.47970K562GLRX3
CYCSENSG00000172115.44439.936307905.85120-0.8324010.241108.69610K562GPKOW
CYCSENSG00000172115.413208.8054015992.98740-0.275903.011102.22460K562GRSF1
CYCSENSG00000172115.48994.1649010962.50020-0.285503.307602.13390K562HNRNPA1
CYCSENSG00000172115.48016.7328011515.18700-0.522503.446601.66830K562HNRNPAB
CYCSENSG00000172115.43174.890906499.27020-1.0336010.263909.17280K562HNRNPC
CYCSENSG00000172115.44308.499105802.62840-0.429502.702601.57590K562HNRNPF
CYCSENSG00000172115.413684.0562010884.731000.330102.845901.59330K562HNRNPK
CYCSENSG00000172115.48709.5629010753.50990-0.304103.439702.24470K562HNRNPL
CYCSENSG00000172115.49594.146007352.545700.383803.349102.31710K562HNRNPM
CYCSENSG00000172115.47865.5107012139.82510-0.6261017.8539015.69720K562HNRNPU
CYCSENSG00000172115.46845.2628010896.09220-0.670607.937305.85560K562IGF2BP2
CYCSENSG00000172115.48324.2016011083.51750-0.413005.083903.37830K562IGF2BP3
CYCSENSG00000172115.42402.853403439.54680-0.517505.548803.45340K562KHDRBS1
CYCSENSG00000172115.44010.755506749.94220-0.751008.341606.61880K562KRR1
CYCSENSG00000172115.49300.7729011453.13570-0.300303.267802.34660K562MAGOH
CYCSENSG00000172115.49576.7330011430.17020-0.255202.599401.70730K562MATR3
CYCSENSG00000172115.44747.023307716.88530-0.701008.007806.47550K562METAP2
CYCSENSG00000172115.46704.153008412.30030-0.327408.002506.69360K562MTPAP
CYCSENSG00000172115.48914.941105874.054800.601803.776702.70470K562NAA15
CYCSENSG00000172115.45883.473609346.91550-0.6678050.7815048.27110K562NSUN2
CYCSENSG00000172115.47402.5540011822.42430-0.675404.567002.94590K562PABPC1
CYCSENSG00000172115.44685.755708754.18520-0.9017013.310309.55840K562PABPC4
CYCSENSG00000172115.45721.249507864.12570-0.459004.728803.64400K562PCBP3
CYCSENSG00000172115.415098.1380019199.47210-0.346705.137503.26120K562PNPT1
CYCSENSG00000172115.44809.441306032.10370-0.326802.422801.67540K562POLR2G
CYCSENSG00000172115.410085.581507642.125000.400103.743702.87110K562PRPF8
CYCSENSG00000172115.44238.150605826.93500-0.459303.083202.12250K562PSIP1
CYCSENSG00000172115.416336.1606021246.96510-0.379208.021706.36030K562PUM2
CYCSENSG00000172115.410717.178706991.062000.616209.368408.41820K562PUS1
CYCSENSG00000172115.48072.160406811.318300.244903.083702.46310K562RBM15
CYCSENSG00000172115.411953.6267015164.96280-0.343304.456402.41580K562RBM17
CYCSENSG00000172115.47590.9014010670.72560-0.491306.734105.35420K562RBM22
CYCSENSG00000172115.43843.594905314.67700-0.467503.479802.37270K562RCC2
CYCSENSG00000172115.45754.438608410.30550-0.547503.895701.82440K562RECQL
CYCSENSG00000172115.47738.149208959.09400-0.211403.241401.53000K562RPS10
CYCSENSG00000172115.44519.864407785.77860-0.784605.069403.96030K562RPS19
CYCSENSG00000172115.47029.2402011208.70470-0.673203.919202.03130K562SBDS
CYCSENSG00000172115.46724.018809222.87970-0.455909.815608.34930K562SF3A3
CYCSENSG00000172115.42948.126207517.81590-1.3505021.0323018.36590K562SF3B1
CYCSENSG00000172115.45539.2146010543.27190-0.928603.904002.24550K562SFPQ
CYCSENSG00000172115.42940.400603752.04500-0.351703.368901.96170K562SLBP
CYCSENSG00000172115.42940.550205038.34220-0.776907.475305.55800K562SRFBP1
CYCSENSG00000172115.47482.433109449.02670-0.3367010.290208.61290K562SRPK2
CYCSENSG00000172115.49294.3505010908.27120-0.231002.362501.70140K562SRSF1
CYCSENSG00000172115.43513.600904471.53070-0.347804.021202.71820K562SRSF4
CYCSENSG00000172115.47953.6608010301.54830-0.373204.084402.76520K562SRSF5
CYCSENSG00000172115.45294.244306852.49110-0.372207.180505.29080K562SRSF7
CYCSENSG00000172115.47169.474909383.58820-0.388307.796205.53610K562SSB
CYCSENSG00000172115.414059.5614017788.06680-0.339402.928601.37940K562SUCLG1
CYCSENSG00000172115.46821.4459011872.98970-0.799503.227401.65140K562SUPT6H
CYCSENSG00000172115.44312.255007401.75690-0.779404.348303.05050K562SUPV3L1
CYCSENSG00000172115.46893.3682011040.31050-0.6795010.938809.37420K562TARDBP
CYCSENSG00000172115.47346.0216010649.51370-0.5358010.182908.49680K562TIA1
CYCSENSG00000172115.43352.887605604.73650-0.741205.302003.96710K562TIAL1
CYCSENSG00000172115.48561.0172010449.32590-0.287602.814401.70860K562TRA2A
CYCSENSG00000172115.43052.208705952.47070-0.963609.336507.36710K562TRIM56
CYCSENSG00000172115.45433.410507832.58320-0.527602.790001.76670K562UCHL5
CYCSENSG00000172115.46413.323209910.72530-0.6279027.1174025.16300K562UPF1
CYCSENSG00000172115.47342.813409301.20210-0.341102.855401.63260K562UTP3
CYCSENSG00000172115.45702.324308480.30680-0.5726010.847909.06480K562WDR3
CYCSENSG00000172115.47967.371908818.45120-0.146402.174201.41690K562WDR43
CYCSENSG00000172115.45180.359007973.76380-0.622203.756002.26890K562XRN2
CYCSENSG00000172115.415268.2336022854.46980-0.581905.103503.87310K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CYCS is not available on ENCORE database.






No RBPs affect the alternative splcing events of CYCS on ENCORE database.





The Knockdown/knockout RNA-Seq assay for CYCS is not avaliable on ENCORE database.