GFPT1

General Information

Gene Name : GFPT1
Gene ID : ENSG00000198380.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: GFPT1)

Not Available

Antibody Validation

Cell Signaling Technology: 5322S

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	GFPT1	ENSG00000198380.12	20.56	17.11	18.84	ENCSR000AEF
HepG2	GFPT1	ENSG00000198380.12	23.11	36.19	29.65	ENCSR985KAT
K562	GFPT1	ENSG00000198380.12	14.24	12.78	13.51	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
GFPT1		5322S	1			Submitted, ENCORE2	BGHcLV45-39, Submitted, ENCORE2	BGKcLV42-37, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
GFPT1	K562	CRISPR			GFPT1-BGKcLV42-37,GFPT1-BGKcLV42-38	NT-BGKcLV42-1,NT-BGKcLV42-2	84.6,85.7	Submitting	ENCORE2
GFPT1	HepG2	CRISPR			GFPT1-BGHcLV45-39,GFPT1-BGHcLV45-40	NT-BGHcLV45-1,NT-BGHcLV45-2	74.2,78.0	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
GFPT1	Product_ID: 5322S Lot_ID: 1 Source: Cell Signaling Technology Target Name: GFPT1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for GFPT1 is not avaliable on ENCORE database.

Proteins bound to RNA

GFPT1 RNA is bound by 43 proteins.

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eCLIP assay for GFPT1 is not avaliable on ENCORE database.

43 proteins are bound to GFPT1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	69549605	69549651	-	3'-UTR,intron-Distal	3.79172	26.53774	K562	UPF1
chr2	69550705	69550758	-	3'-UTR,intron-Distal	6.06569	25.56443	K562	LIN28B
chr2	69597041	69597110	-	intron-Distal,intron-Proximal	5.00951	21.86268	HepG2	PCBP2
chr2	69590674	69590778	-	CDS,intron-Distal,intron-Proximal	3.26162	21.10253	HepG2	BCLAF1
chr2	69550652	69550705	-	3'-UTR,intron-Distal	6.57822	20.82694	K562	LIN28B
chr2	69551498	69551561	-	3'-UTR,intron-Distal	4.60554	19.03606	HepG2	FUBP3
chr2	69613991	69614094	-	intron-Distal	4.24157	18.45875	HepG2	PRPF4
chr2	69583654	69583705	-	CDS,intron-Distal,intron-Proximal	5.19523	18.21623	HepG2	U2AF2
chr2	69549919	69549990	-	3'-UTR,intron-Distal	4.82486	18.08989	K562	UPF1
chr2	69590680	69590803	-	CDS,intron-Distal,intron-Proximal	3.00821	16.97396	HepG2	GRWD1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 190 entries

eCLIP assay for GFPT1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for GFPT1 is not available on ENCORE database.
126 RBPs can affect the levels of GFPT1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for GFPT1 is not available on ENCORE database.

126 RBPs can affect the gene expression of GFPT1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
GFPT1	ENSG00000198380.8	1822.90930	5316.13430	-1.54410	86.34040	83.75380	HepG2	UTP3
GFPT1	ENSG00000198380.8	1713.66550	4462.97430	-1.38090	75.91130	73.20450	HepG2	DDX19B
GFPT1	ENSG00000198380.8	1313.52920	3941.73300	-1.58540	57.03480	54.89510	HepG2	HNRNPA1
GFPT1	ENSG00000198380.8	2441.23860	4523.29600	-0.88980	54.76960	52.60850	HepG2	SMN1
GFPT1	ENSG00000198380.8	2220.55040	4825.38480	-1.11970	48.39420	46.62810	HepG2	ACO1
GFPT1	ENSG00000198380.8	9248.21460	3605.82120	1.35870	43.08770	40.52230	K562	HSPD1
GFPT1	ENSG00000198380.8	4681.17410	7669.67720	-0.71230	34.86670	33.61180	HepG2	SRFBP1
GFPT1	ENSG00000198380.8	1997.49560	3904.33030	-0.96690	35.78570	33.59320	HepG2	DNAJC21
GFPT1	ENSG00000198380.8	2727.31250	4824.73780	-0.82300	33.62800	31.89940	HepG2	CKAP4
GFPT1	ENSG00000198380.8	2406.74600	3869.68920	-0.68510	29.66790	27.76000	HepG2	DNAJC2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 154 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for GFPT1 is not available on ENCORE database.

7 RBPs can affect the splicing of GFPT1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	GFPT1	ENSG00000198380.8	chr2	-	69565029	69565187			69556815	69556930	69569283	69569430	-0.09800	0.00000	0.00007	excluded	K562	AQR
SE	GFPT1	ENSG00000198380.8	chr2	-	69610055	69610215			69601137	69601245	69614196	69614382	0.09000	0.00000	0.00010	included	HepG2	SRSF1
A3SS	GFPT1	ENSG00000198380.8	chr2	-	69554045	69554289			69554045	69554207	69555402	69555536	0.11500	0.00000	0.00000	longer	K562	AQR
A3SS	GFPT1	ENSG00000198380.8	chr2	-	69555402	69555604			69555402	69555570	69556428	69556652	0.05200	0.00000	0.00000	longer	K562	AQR
A3SS	GFPT1	ENSG00000198380.8	chr2	-	69565576	69565757			69565576	69565697	69569283	69569381	0.16500	0.00000	0.00000	longer	K562	AQR
MXE	GFPT1	ENSG00000198380.8	chr2	-	69565029	69565187	69565576	69565757	69556815	69556930	69569283	69569381	0.08000	0.00000	0.00000	1included	K562	AQR
SE	GFPT1	ENSG00000198380.8	chr2	-	69565576	69565697			69556762	69556930	69569283	69569381	-0.10900	0.00001	0.00056	excluded	K562	SF3B4
MXE	GFPT1	ENSG00000198380.8	chr2	-	69556815	69556930	69565576	69565697	69556428	69556556	69569283	69569381	-0.14500	0.00002	0.00032	2included	HepG2	U2AF2
MXE	GFPT1	ENSG00000198380.8	chr2	-	69597132	69597240	69601137	69601245	69590742	69590802	69614196	69614382	-0.09400	0.00004	0.00468	2included	HepG2	TBRG4
MXE	GFPT1	ENSG00000198380.8	chr2	-	69597132	69597240	69601137	69601245	69590742	69590802	69614196	69614382	0.11500	0.00267	0.07437	1included	HepG2	NCBP2

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

GFPT1

General Information

Functions

Localization

Domains (AlphaFold: GFPT1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for GFPT1 is not avaliable on ENCORE database.

43 proteins are bound to GFPT1 RNA:

eCLIP assay for GFPT1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for GFPT1 is not available on ENCORE database.

126 RBPs can affect the gene expression of GFPT1 :

The Knockdown/knockout RNA-Seq assay for GFPT1 is not available on ENCORE database.

7 RBPs can affect the splicing of GFPT1 :

The Knockdown/knockout RNA-Seq assay for GFPT1 is not avaliable on ENCORE database.