UXS1

General Information

Gene Name       : UXS1
Gene ID             : ENSG00000115652.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: UXS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UXS1ENSG00000115652.1421.0617.3119.18ENCSR000AEF
HepG2UXS1ENSG00000115652.1495.36108.59101.97ENCSR985KAT
K562UXS1ENSG00000115652.1416.4717.3416.91ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UXS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • UXS1 RNA is bound by 26 proteins.  







eCLIP assay for UXS1 is not avaliable on ENCORE database.





26 proteins are bound to UXS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2106710168106710227-3'-UTR,intron-Distal3.738303.43811HepG2TIA1
chr2106709804106709887-3'-UTR,intron-Distal,intron-Proximal6.264647.33718HepG2DDX6
chr2106709813106709874-3'-UTR,intron-Distal,intron-Proximal3.677267.84285HepG2IGF2BP1
chr2106709803106709902-3'-UTR,intron-Distal,intron-Proximal3.772148.04108HepG2DDX55
chr2106746129106746236-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.078763.68829K562YBX3
chr2106709814106709865-3'-UTR,intron-Distal,intron-Proximal3.017783.86886HepG2TROVE2
chr2106709786106709818-3'-UTR,intron-Distal4.211813.15159HepG2LARP4
chr2106709807106709871-3'-UTR,intron-Distal,intron-Proximal4.148234.04453HepG2IGF2BP3
chr2106709823106709874-3'-UTR,intron-Distal,intron-Proximal3.043543.27623HepG2TIA1
chr2106810642106810729-5'-UTR,CDS,intron-Distal4.433808.04211K562DDX3X
chr2106810598106810642-5'-UTR,CDS,intron-Distal5.411407.12859K562DDX3X
chr2106782511106782539-5'-UTR,CDS,intron-Distal,intron-Proximal3.7867217.06640HepG2DDX3X
chr2106810708106810755-5'-UTR,intron-Distal6.0152388.25012HepG2DDX3X
chr2106761647106761707-5'-UTR,CDS,intron-Distal,intron-Proximal3.634623.01531K562YBX3
chr2106810602106810645-5'-UTR,CDS,intron-Distal4.9055061.25719HepG2DDX3X
chr2106810516106810614-5'-UTR,CDS,intron-Distal4.6321019.13701HepG2PRPF8
chr2106810705106810756-5'-UTR,intron-Distal,intron-Proximal4.1825712.15891HepG2NCBP2
chr2106810645106810708-5'-UTR,CDS,intron-Distal5.57688400.00000HepG2DDX3X
chr2106721249106721294-CDS,intron-Distal,intron-Proximal4.491455.54796HepG2LIN28B
chr2106729063106729138-CDS,intron-Distal,intron-Proximal5.4765728.63238HepG2PRPF8
chr2106742037106742090-CDS,intron-Distal,intron-Proximal3.645306.95612HepG2PRPF8
chr2106742074106742136-CDS,intron-Distal,intron-Proximal4.367228.83838HepG2SND1
chr2106739456106739527-CDS,intron-Distal,intron-Proximal3.415717.86497HepG2SND1
chr2106712596106712742-intron-Distal5.5711411.63976K562HNRNPL
chr2106794889106794943-intron-Distal4.334395.10284K562HNRNPL
chr2106795034106795099-intron-Distal3.9719411.65862K562HNRNPL
chr2106712677106712742-intron-Distal4.8182425.61768K562AGGF1
chr2106771538106771573-intron-Distal3.454634.81844HepG2SUGP2
chr2106712819106712918-intron-Distal5.240908.16758K562HNRNPL
chr2106795069106795093-intron-Distal4.184899.44047HepG2HNRNPL
chr2106795093106795108-intron-Distal4.542033.45317HepG2HNRNPL
chr2106770709106770764-intron-Distal4.213444.31720HepG2MATR3
chr2106771639106771676-intron-Distal3.472514.57452HepG2SUGP2
chr2106794854106794928-intron-Distal4.082436.59866K562AGGF1
chr2106712603106712655-intron-Distal6.7546225.00481K562AGGF1
chr2106738916106739015-intron-Distal3.665395.98773K562KHSRP
chr2106810514106810570-intron-Distal4.571387.82992HepG2RBM22
chr2106768867106768928-intron-Distal4.627035.07733HepG2PTBP1
chr2106770657106770694-intron-Distal3.336155.59320HepG2SUGP2
chr2106770265106770323-intron-Distal3.962356.77642HepG2SUGP2
chr2106769244106769324-intron-Distal3.804796.25619HepG2SUGP2
chr2106795035106795048-intron-Distal3.186254.63384HepG2HNRNPL
chr2106768509106768555-intron-Distal4.053544.03915HepG2SUGP2
chr2106794785106794840-intron-Distal3.878736.25849HepG2HNRNPL
chr2106768385106768439-intron-Distal3.272244.14346HepG2SUGP2
chr2106801341106801382-intron-Distal4.293576.92280HepG2HNRNPM
chr2106769929106769978-intron-Distal3.270763.34056HepG2MATR3
chr2106787125106787146-intron-Distal3.804344.86210HepG2HNRNPM
chr2106794861106794897-intron-Distal4.820387.07589HepG2HNRNPL
chr2106712625106712692-intron-Distal4.4286320.12524HepG2HNRNPL
chr2106794774106794847-intron-Distal3.385674.26070K562HNRNPL
chr2106712449106712567-intron-Distal4.932728.58650K562HNRNPL
chr2106769280106769332-intron-Distal3.161363.00914HepG2PTBP1
chr2106769914106769979-intron-Distal5.5647211.33240HepG2SUGP2
chr2106717014106717071-intron-Distal,intron-Proximal4.373053.97974HepG2RBFOX2
chr2106712811106712926-intron-Distal4.7747521.49670HepG2HNRNPL
chr2106769501106769546-intron-Distal4.486665.04879HepG2SUGP2
chr2106768966106769038-intron-Distal5.012297.64200HepG2PTBP1
chr2106794951106794977-intron-Distal3.322903.65621HepG2HNRNPL
chr2106712492106712565-intron-Distal4.262646.73795HepG2HNRNPL
chr2106771144106771184-intron-Distal4.394454.53347HepG2SUGP2
chr2106772748106772839-intron-Distal4.459255.15027HepG2MATR3
chr2106735971106736100-intron-Distal4.064403.27946HepG2HNRNPM
chr2106712607106712679-intron-Distal3.257946.70671HepG2AGGF1
chr2106769384106769424-intron-Distal3.399124.33009HepG2SUGP2
chr2106712659106712751-intron-Distal4.748745.11000HepG2CDC40
chr2106805744106805817-intron-Distal3.373543.59523HepG2SUGP2
chr2106772088106772143-intron-Distal3.936306.25619HepG2SUGP2
chr2106770269106770332-intron-Distal4.237443.27829HepG2MATR3
chr2106712828106712906-intron-Distal5.8485025.55701K562AGGF1
chr2106794978106795034-intron-Distal5.5284612.79712K562HNRNPL
chr2106768262106768352-intron-Distal3.003773.79703HepG2SUGP2
chr2106712692106712786-intron-Distal4.1267115.10582HepG2HNRNPL
chr2106770694106770743-intron-Distal3.299115.35016HepG2SUGP2
chr2106781073106781152-intron-Distal,intron-Proximal4.215913.12843K562PRPF8
chr2106712820106712918-intron-Distal4.208456.88493HepG2AGGF1
chr2106772286106772354-intron-Distal3.122296.57022HepG2SUGP2
chr2106794977106795035-intron-Distal3.640099.99770HepG2HNRNPL
chr2106712633106712697-intron-Distal4.133443.85108HepG2GTF2F1
chr2106798418106798487-intron-Distal3.496283.35377HepG2QKI
chr2106795152106795207-intron-Distal4.094193.84437HepG2PRPF4
chr2106794897106794951-intron-Distal3.897979.20850HepG2HNRNPL
chr2106787146106787170-intron-Distal3.962095.63625HepG2HNRNPM
chr2106795048106795069-intron-Distal3.754977.30047HepG2HNRNPL
chr2106766514106766580-intron-Distal3.207253.59523HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UXS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UXS1 is not available on ENCORE database.

  • 80 RBPs can affect the levels of UXS1.  








The Knockdown/knockout RNA-Seq assay for UXS1 is not available on ENCORE database.





80 RBPs can affect the gene expression of UXS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UXS1ENSG00000115652.101350.362002115.18900-0.647406.855705.45350HepG2ABCF1
UXS1ENSG00000115652.101977.140201508.310100.390403.331502.24430HepG2ADAR
UXS1ENSG00000115652.103409.477602451.458700.475803.950303.33200HepG2AKAP1
UXS1ENSG00000115652.101356.274001605.73940-0.243602.561301.82020HepG2AKAP8L
UXS1ENSG00000115652.101458.075002028.38820-0.476304.270403.30360HepG2ASCC1
UXS1ENSG00000115652.102636.151202240.840700.234303.094502.37470HepG2AUH
UXS1ENSG00000115652.102130.391302654.53750-0.317302.173301.63810HepG2BOP1
UXS1ENSG00000115652.102190.819901741.942300.330703.233902.03610HepG2CPSF7
UXS1ENSG00000115652.103967.507602523.039900.6530018.7867017.41370HepG2CELF1
UXS1ENSG00000115652.103146.759202712.769000.214003.532202.71200HepG2DAZAP1
UXS1ENSG00000115652.101047.727001478.09760-0.496509.908208.51820HepG2DDX19B
UXS1ENSG00000115652.10701.412501548.92400-1.1429031.4505028.43750HepG2DDX1
UXS1ENSG00000115652.101271.466801556.08510-0.291402.231701.61530HepG2DDX21
UXS1ENSG00000115652.101241.201202348.33760-0.9199013.7383012.44970HepG2DDX3X
UXS1ENSG00000115652.10730.906701529.00970-1.0648031.4464029.80540HepG2DKC1
UXS1ENSG00000115652.101246.537001518.82020-0.285002.963802.24080HepG2DNAJC21
UXS1ENSG00000115652.10614.335201505.35150-1.2930054.4403051.85120HepG2DNAJC2
UXS1ENSG00000115652.101380.600501717.51720-0.315002.189301.36770HepG2EEF2
UXS1ENSG00000115652.101914.785401432.756300.418302.670901.58670HepG2AGO1
UXS1ENSG00000115652.101197.252301469.33670-0.295402.520801.48950HepG2EIF3G
UXS1ENSG00000115652.102165.084102676.41510-0.305904.372703.36340HepG2EIF4G1
UXS1ENSG00000115652.101153.146402563.81610-1.1527025.2846023.05780HepG2EIF4G2
UXS1ENSG00000115652.103052.504102572.735800.246603.271602.62650HepG2ETF1
UXS1ENSG00000115652.103452.818702135.840200.692907.979306.74830HepG2FIP1L1
UXS1ENSG00000115652.101588.470902441.12910-0.619902.425001.47980HepG2FTO
UXS1ENSG00000115652.101675.164001337.365200.324802.939102.13050HepG2FUBP3
UXS1ENSG00000115652.103035.388001944.119000.642705.136703.64450HepG2FUS
UXS1ENSG00000115652.101462.746002005.84280-0.455503.644902.88600HepG2G3BP1
UXS1ENSG00000115652.101680.000502762.74950-0.717608.033406.98170HepG2GPKOW
UXS1ENSG00000115652.101935.496301525.830600.343005.141003.85270HepG2HDGF
UXS1ENSG00000115652.101044.146501533.37020-0.554406.732405.79030HepG2HNRNPA1
UXS1ENSG00000115652.101538.562002429.91320-0.6593011.182609.86900HepG2HNRNPF
UXS1ENSG00000115652.102132.158502636.52940-0.306302.045101.49550HepG2HNRNPLL
UXS1ENSG00000115652.101397.595902392.79830-0.7758011.059609.70660HepG2IGF2BP1
UXS1ENSG00000115652.101489.724101730.67170-0.216302.710001.98400HepG2ILF2
UXS1ENSG00000115652.101712.042302162.99680-0.337302.334601.73070HepG2MAGOH
UXS1ENSG00000115652.101918.936801451.538100.402604.141202.65760HepG2NAA15
UXS1ENSG00000115652.10798.250402226.36480-1.4798030.7628028.83070HepG2NCBP2
UXS1ENSG00000115652.102132.696501677.087800.346605.195804.08190HepG2PARN
UXS1ENSG00000115652.101629.905401980.67690-0.281203.575702.90410HepG2PCBP1
UXS1ENSG00000115652.101754.649801511.181000.215401.938401.31280HepG2PPIL4
UXS1ENSG00000115652.101756.502102015.44940-0.198401.982601.50590HepG2PTBP1
UXS1ENSG00000115652.101785.267702567.85640-0.524407.063306.16730HepG2PUF60
UXS1ENSG00000115652.102898.093101776.117200.706304.631303.73150HepG2RAVER1
UXS1ENSG00000115652.10865.753201975.77960-1.1904023.1532020.37110HepG2RBM27
UXS1ENSG00000115652.101494.789402242.97120-0.5855012.8865011.87760HepG2NELFE
UXS1ENSG00000115652.101603.772202089.07800-0.381406.076905.21260HepG2RECQL
UXS1ENSG00000115652.101511.213802617.20140-0.7923013.2733011.97920HepG2RPLP0
UXS1ENSG00000115652.101397.361201832.46080-0.391102.248101.52690HepG2RPS3A
UXS1ENSG00000115652.101756.600101508.857700.219202.562201.93780HepG2SAFB2
UXS1ENSG00000115652.101576.061602609.72850-0.727606.897205.82450HepG2SF3B1
UXS1ENSG00000115652.101531.130502098.27730-0.454608.193507.25900HepG2SF3B4
UXS1ENSG00000115652.102205.708001759.601800.325906.166605.26600HepG2SMN1
UXS1ENSG00000115652.102489.154902190.174000.184502.073801.64810HepG2SRSF1
UXS1ENSG00000115652.102848.198302535.430100.167701.864801.33710HepG2SRSF5
UXS1ENSG00000115652.101732.270502387.21460-0.462706.000005.03800HepG2SRSF7
UXS1ENSG00000115652.10898.478502108.76120-1.2308051.9530050.41580HepG2SSB
UXS1ENSG00000115652.101832.914201442.247800.345703.688202.61360HepG2SUPT6H
UXS1ENSG00000115652.102787.933301968.688100.501909.719008.77080HepG2TAF15
UXS1ENSG00000115652.103215.459202569.408400.323502.904602.16430HepG2TARDBP
UXS1ENSG00000115652.101251.468601646.39720-0.395704.614704.00370HepG2TIAL1
UXS1ENSG00000115652.101851.131801610.868000.200501.997201.47100HepG2UTP3
UXS1ENSG00000115652.10914.661201705.04330-0.898506.879305.75120HepG2XRN2
UXS1ENSG00000115652.101190.145401536.89760-0.368905.773904.85860HepG2ZC3H8
UXS1ENSG00000115652.102268.466201835.026300.305805.654304.94430HepG2ZNF622
UXS1ENSG00000115652.10510.22340659.54750-0.370302.275701.73590K562AQR
UXS1ENSG00000115652.10692.61030534.118100.374803.279802.27860K562ATP5C1
UXS1ENSG00000115652.10310.85920410.18260-0.400002.473601.56930K562BCLAF1
UXS1ENSG00000115652.10449.38220621.91200-0.468803.578602.68730K562CPSF6
UXS1ENSG00000115652.10704.67850547.713500.363403.211502.25900K562DKC1
UXS1ENSG00000115652.10241.64250374.96160-0.633903.401701.97810K562EEF2
UXS1ENSG00000115652.10717.61010559.898700.357902.980702.23890K562EIF2S2
UXS1ENSG00000115652.10245.62540387.01450-0.655904.271003.54570K562HNRNPC
UXS1ENSG00000115652.10680.12280540.189900.332202.253201.51890K562KIF1C
UXS1ENSG00000115652.10309.85510445.44500-0.523703.704002.62490K562MATR3
UXS1ENSG00000115652.10246.70690352.51870-0.514902.550001.83010K562PRPF8
UXS1ENSG00000115652.101506.48300951.116600.6634010.582408.42670K562PUM1
UXS1ENSG00000115652.101123.53970931.935300.269602.303201.42610K562PUM2
UXS1ENSG00000115652.10613.58930491.869100.318902.239201.69640K562RBM15
UXS1ENSG00000115652.10259.81130359.04350-0.466702.046701.34980K562RPS19
UXS1ENSG00000115652.10645.75090425.091100.603105.603804.60350K562SRSF1
UXS1ENSG00000115652.10438.23180551.11510-0.330702.353501.68800K562UPF1
UXS1ENSG00000115652.10501.81030781.28280-0.638706.300404.34830K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UXS1 is not available on ENCORE database.





12 RBPs can affect the splicing of UXS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUXS1ENSG00000115652.10chr2-1067151711067152291067097701067106131067175131067175740.064000.000240.00618includedHepG2U2AF1
SEUXS1ENSG00000115652.10chr2-1067131731067132771067097581067106131067151711067152290.060000.000010.00522includedHepG2ILF3
SEUXS1ENSG00000115652.10chr2-106742075106742165106739426106739547106746129106746234-0.060000.000750.02129excludedHepG2HNRNPK
SEUXS1ENSG00000115652.10chr2-1067151711067152291067097701067106131067175131067175740.071000.000100.01033includedHepG2AKAP1
SEUXS1ENSG00000115652.10chr2-106742075106742135106739425106739547106746129106746234-0.106000.001740.01948excludedK562AQR
SEUXS1ENSG00000115652.10chr2-106715171106715229106713173106713277106717513106717574-0.079000.003650.04879excludedK562PUS1
SEUXS1ENSG00000115652.10chr2-1067131731067132771067097581067106131067151711067152290.079000.000100.02372includedHepG2HNRNPA1
SEUXS1ENSG00000115652.10chr2-1067151711067152291067097701067106131067175131067175740.081000.000430.02234includedHepG2MATR3
SEUXS1ENSG00000115652.10chr2-106713173106713277106709758106710613106717513106717574-0.109000.000190.01885excludedK562HNRNPL
SEUXS1ENSG00000115652.10chr2-1067151711067152291067097701067106131067175131067175740.067000.001370.03300includedHepG2SRSF1
SEUXS1ENSG00000115652.10chr2-106713173106713277106709758106710613106715171106715229-0.063000.001940.07927excludedHepG2PCBP1
A3SSUXS1ENSG00000115652.10chr2-1067811911067812551067811911067812401067825111067825390.322000.011070.05765longerK562AQR
A3SSUXS1ENSG00000115652.10chr2-1067461291067463061067461291067462341067616451067618260.053000.000410.00311longerK562AQR
MXEUXS1ENSG00000115652.10chr2-106713173106713277106715171106715229106709758106710613106717513106717574-0.155000.000160.004862includedK562PUS1
MXEUXS1ENSG00000115652.10chr2-106713173106713277106715171106715229106709758106710613106717513106717574-0.102000.000030.000362includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UXS1 is not avaliable on ENCORE database.