SDHC

General Information

Gene Name       : SDHC
Gene ID             : ENSG00000143252.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SDHC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SDHCENSG00000143252.14236.60194.05215.32ENCSR000AEF
HepG2SDHCENSG00000143252.14171.44249.97210.70ENCSR985KAT
K562SDHCENSG00000143252.14180.02197.16188.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SDHC is not avaliable on ENCORE database.



Proteins bound to RNA
  • SDHC RNA is bound by 15 proteins.  







eCLIP assay for SDHC is not avaliable on ENCORE database.





15 proteins are bound to SDHC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1161332567161332626+3'-UTR,intron-Proximal4.9168847.62353HepG2GRSF1
chr1161332584161332655+3'-UTR,intron-Proximal3.354205.91053HepG2LARP4
chr1161332566161332660+3'-UTR,intron-Proximal3.4745018.20475HepG2PRPF4
chr1161332579161332672+3'-UTR,intron-Proximal3.578228.93588HepG2FAM120A
chr1161332339161332360+3'-UTR,intron-Distal3.419334.48159HepG2LARP4
chr1161332627161332660+3'-UTR,intron-Proximal6.0687832.27563K562UPF1
chr1161332338161332419+3'-UTR,intron-Distal4.241237.11997HepG2SUB1
chr1161332629161332661+3'-UTR,intron-Proximal4.1889221.42845K562FAM120A
chr1161332580161332629+3'-UTR,intron-Proximal3.8943725.64346K562FAM120A
chr1161332536161332667+3'-UTR,intron-Distal,intron-Proximal6.6842426.00782HepG2UPF1
chr1161332772161332808+3'-UTR5.045377.60978K562UPF1
chr1161326592161326631+3'-UTR,CDS,intron-Distal,intron-Proximal4.140776.73573K562PUM2
chr1161332564161332659+3'-UTR,intron-Proximal3.789426.58563HepG2DDX55
chr1161332626161332668+3'-UTR,intron-Proximal5.4359741.59252HepG2GRSF1
chr1161332573161332627+3'-UTR,intron-Proximal7.2005235.57070K562UPF1
chr1161332577161332665+3'-UTR,intron-Proximal4.168657.20393HepG2AKAP1
chr1161326464161326509+3'-UTR,CDS,intron-Distal,intron-Proximal6.2797911.12661K562RPS3
chr1161326601161326631+3'-UTR,CDS,intron-Distal,intron-Proximal3.574054.22960K562SND1
chr1161332334161332396+3'-UTR,intron-Distal3.4731812.78246K562UPF1
chr1161284175161284216+5'-UTR,CDS,intron-Proximal3.886234.84938K562DDX3X
chr1161284171161284267+5'-UTR,CDS,intron-Proximal3.449683.87702HepG2NCBP2
chr1161284176161284275+5'-UTR,CDS,intron-Proximal4.319507.13970HepG2PRPF8
chr1161293403161293432+CDS,intron-Distal,intron-Proximal3.533955.06399K562DDX3X
chr1161293432161293461+CDS,intron-Distal,intron-Proximal3.109955.21590K562DDX3X
chr1161312992161313087+intron-Distal3.982413.60235HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SDHC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SDHC is not available on ENCORE database.

  • 95 RBPs can affect the levels of SDHC.  








The Knockdown/knockout RNA-Seq assay for SDHC is not available on ENCORE database.





95 RBPs can affect the gene expression of SDHC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SDHCENSG00000143252.102444.485603522.04000-0.526905.589904.49530HepG2ASCC1
SDHCENSG00000143252.103194.931703781.79250-0.243303.465202.71220HepG2AUH
SDHCENSG00000143252.101305.264802071.60410-0.666406.807105.46730HepG2BCLAF1
SDHCENSG00000143252.101372.145501918.91800-0.483903.340602.26080HepG2CCAR1
SDHCENSG00000143252.101837.411202114.37410-0.202602.589801.94200HepG2CKAP4
SDHCENSG00000143252.102756.723601601.044800.783806.196705.05160HepG2CNOT7
SDHCENSG00000143252.101946.934003015.57020-0.6312015.6524014.36890HepG2CELF1
SDHCENSG00000143252.103328.474404077.68100-0.292902.019301.47580HepG2DDX3X
SDHCENSG00000143252.101809.660402343.91620-0.373202.313801.60040HepG2DDX55
SDHCENSG00000143252.10782.396201138.73120-0.541502.447801.52880HepG2DDX59
SDHCENSG00000143252.102563.353503502.25160-0.450303.634202.93420HepG2DDX6
SDHCENSG00000143252.101413.697601764.19320-0.319505.254004.40040HepG2DNAJC2
SDHCENSG00000143252.102178.058103367.35600-0.628607.164306.24250HepG2EIF2S1
SDHCENSG00000143252.102484.263203622.97960-0.544404.056303.23090HepG2EIF4B
SDHCENSG00000143252.102579.226703198.88840-0.310603.385702.47510HepG2EIF4G1
SDHCENSG00000143252.102442.529503064.31120-0.327202.787801.96980HepG2EIF4G2
SDHCENSG00000143252.103234.629504341.96860-0.424709.822008.80120HepG2ETF1
SDHCENSG00000143252.102966.887003754.11710-0.339502.315501.68030HepG2FXR1
SDHCENSG00000143252.102828.611303697.00890-0.386303.399302.40400HepG2G3BP2
SDHCENSG00000143252.10564.594301136.75650-1.0096012.3978011.13290HepG2GPKOW
SDHCENSG00000143252.101724.708902019.06360-0.227302.612401.65940HepG2HDGF
SDHCENSG00000143252.101630.652001998.79940-0.293702.368101.72120HepG2HNRNPC
SDHCENSG00000143252.102517.148602953.49890-0.230603.835503.05020HepG2HNRNPL
SDHCENSG00000143252.10766.522701084.82550-0.501104.074203.32570HepG2HNRNPLL
SDHCENSG00000143252.101412.858301985.58480-0.490909.864708.77630HepG2HNRNPU
SDHCENSG00000143252.102747.165603540.46720-0.366002.736102.06370HepG2IGF2BP2
SDHCENSG00000143252.101359.559602028.21000-0.5771016.6431015.02160HepG2ILF2
SDHCENSG00000143252.101672.378501933.22550-0.209102.655501.65410HepG2KIF1C
SDHCENSG00000143252.101002.324701490.46590-0.572404.217502.66510HepG2KRR1
SDHCENSG00000143252.102433.526603755.42410-0.625907.411006.35100HepG2MAGOH
SDHCENSG00000143252.102794.486503865.64250-0.468104.244403.46540HepG2NCBP2
SDHCENSG00000143252.102592.845803215.11840-0.310303.751002.86020HepG2NOL12
SDHCENSG00000143252.10977.443101463.24040-0.582103.121702.17560HepG2PABPC1
SDHCENSG00000143252.102517.699903443.10170-0.451604.081003.21530HepG2PABPC4
SDHCENSG00000143252.101558.319901965.39480-0.334804.732703.65890HepG2PARN
SDHCENSG00000143252.102218.656103547.67220-0.6772021.8442020.40260HepG2PCBP1
SDHCENSG00000143252.101533.553902244.77700-0.549703.629102.44830HepG2PCBP2
SDHCENSG00000143252.101110.055401770.98380-0.6739013.7145012.15030HepG2PPIL4
SDHCENSG00000143252.101020.988901834.93980-0.8458023.7818021.92490HepG2PRPF4
SDHCENSG00000143252.102433.275503609.87060-0.5690015.6661014.56740HepG2PTBP1
SDHCENSG00000143252.102385.780203258.07430-0.4496013.0651011.97800HepG2PUM1
SDHCENSG00000143252.102549.214903255.66960-0.352903.879603.08850HepG2PUM2
SDHCENSG00000143252.102636.993203909.61840-0.5681012.0541010.88520HepG2QKI
SDHCENSG00000143252.101519.369602166.36370-0.511802.560701.88160HepG2RAVER1
SDHCENSG00000143252.102314.933803548.21510-0.6161010.930509.65070HepG2RBM25
SDHCENSG00000143252.101537.156202472.63780-0.685808.771806.99720HepG2RBM27
SDHCENSG00000143252.102401.659304017.45480-0.7423026.0972024.77880HepG2NELFE
SDHCENSG00000143252.102432.686703741.68530-0.6211019.0226017.64830HepG2RECQL
SDHCENSG00000143252.101088.748802127.84350-0.966709.353907.72120HepG2RPS10
SDHCENSG00000143252.101008.515901241.96960-0.300402.379801.80550HepG2RPS19
SDHCENSG00000143252.101147.010601788.92330-0.641205.966204.85830HepG2RRP9
SDHCENSG00000143252.101285.249801768.25380-0.460309.115808.05430HepG2SAFB2
SDHCENSG00000143252.101086.326601513.59990-0.478503.283701.86300HepG2SART3
SDHCENSG00000143252.10687.672201073.77650-0.642906.683105.62680HepG2SF3B1
SDHCENSG00000143252.101916.316003758.37440-0.9718042.4151040.62500HepG2SF3B4
SDHCENSG00000143252.102485.903802942.91510-0.243503.909503.09780HepG2SLBP
SDHCENSG00000143252.101534.374002062.08730-0.426509.505408.42710HepG2SMN1
SDHCENSG00000143252.103194.871504098.93620-0.359507.858807.13360HepG2SRFBP1
SDHCENSG00000143252.103428.478703922.91570-0.194402.766802.29370HepG2SRSF1
SDHCENSG00000143252.102135.754203030.38290-0.5048011.7426010.57850HepG2SRSF5
SDHCENSG00000143252.102312.686203191.48920-0.4647011.4282010.44140HepG2SRSF9
SDHCENSG00000143252.10953.857901398.08810-0.551604.060902.70760HepG2STIP1
SDHCENSG00000143252.102401.155403446.33910-0.5213015.8837014.59090HepG2SUCLG1
SDHCENSG00000143252.102617.732603526.03200-0.429707.789306.92530HepG2TAF15
SDHCENSG00000143252.102302.183303239.98290-0.493007.621006.24800HepG2TIA1
SDHCENSG00000143252.101599.387901929.38380-0.270602.653502.16210HepG2TIAL1
SDHCENSG00000143252.101373.224401946.61270-0.503407.092006.26150HepG2TRIM56
SDHCENSG00000143252.102458.409202998.49140-0.286502.737701.86920HepG2TUFM
SDHCENSG00000143252.101238.849401707.30840-0.462704.566503.77000HepG2U2AF1
SDHCENSG00000143252.102325.915003173.89900-0.448503.622302.65730HepG2UBE2L3
SDHCENSG00000143252.101333.682101679.46620-0.332604.261703.54390HepG2UTP3
SDHCENSG00000143252.102176.362701810.899000.265102.218201.60720HepG2ZC3H8
SDHCENSG00000143252.101251.656902164.20050-0.790007.687205.40940HepG2ZRANB2
SDHCENSG00000143252.102068.952601640.540100.334604.891704.17210K562AGGF1
SDHCENSG00000143252.102081.623301707.050500.286102.297701.70120K562AKAP8L
SDHCENSG00000143252.102507.098303246.05850-0.372703.912303.23840K562AQR
SDHCENSG00000143252.101639.510501928.11990-0.233902.690101.74210K562BCLAF1
SDHCENSG00000143252.10441.08180845.92110-0.939505.314303.74590K562CCAR1
SDHCENSG00000143252.103202.785104000.93680-0.321003.825502.66850K562CELF1
SDHCENSG00000143252.101371.357901663.91020-0.279002.530101.37390K562DDX21
SDHCENSG00000143252.101394.676502062.86060-0.5647012.0729010.81640K562DDX47
SDHCENSG00000143252.10560.29400946.90140-0.757004.029102.37520K562DHX30
SDHCENSG00000143252.102274.894001836.945400.308403.905102.84130K562DKC1
SDHCENSG00000143252.101652.382801983.29590-0.263402.934602.19710K562EIF2S2
SDHCENSG00000143252.10422.09250860.49100-1.027604.361003.07350K562EIF3A
SDHCENSG00000143252.101248.548301604.85710-0.362204.456603.45790K562EIF3G
SDHCENSG00000143252.101173.697001533.40900-0.385703.466402.55180K562EIF4A3
SDHCENSG00000143252.102739.782103254.11430-0.248202.611301.69570K562EIF4G2
SDHCENSG00000143252.101940.488001511.397400.360403.281402.35410K562FIP1L1
SDHCENSG00000143252.10841.549301066.34430-0.341602.120301.32520K562FTO
SDHCENSG00000143252.10646.525001180.56260-0.8687013.0539011.30680K562GPKOW
SDHCENSG00000143252.10841.869601280.16470-0.604707.349606.42250K562HNRNPC
SDHCENSG00000143252.102031.523802467.97680-0.280803.197502.24010K562HNRNPU
SDHCENSG00000143252.102015.472602498.55890-0.310002.831301.98090K562MAGOH
SDHCENSG00000143252.101454.12690933.069900.640002.213201.34890K562PABPN1
SDHCENSG00000143252.101680.747402223.01730-0.403404.323803.09630K562PCBP2
SDHCENSG00000143252.102266.823301715.894000.401603.891102.89410K562PPIG
SDHCENSG00000143252.102504.649801692.967800.565007.188806.35980K562PUS1
SDHCENSG00000143252.101920.488501649.507200.219301.940301.42840K562RBM15
SDHCENSG00000143252.101624.004502327.47720-0.519206.243504.91340K562RBM22
SDHCENSG00000143252.101768.817802269.03260-0.359302.875001.46670K562RBM34
SDHCENSG00000143252.101185.679901580.51960-0.414707.027204.57390K562RPS10
SDHCENSG00000143252.101223.985801574.33730-0.363202.175601.45510K562RPS19
SDHCENSG00000143252.10847.199801122.73390-0.406202.593101.65280K562SF3B1
SDHCENSG00000143252.101522.843901873.62620-0.299102.857101.98830K562SF3B4
SDHCENSG00000143252.101918.219302408.45390-0.328302.627101.93590K562TARDBP
SDHCENSG00000143252.101834.093002323.25410-0.341103.611602.65720K562TIA1
SDHCENSG00000143252.101833.646202280.05850-0.314402.764401.67410K562TRA2A
SDHCENSG00000143252.101342.278401675.91080-0.320304.748003.66610K562WDR43
SDHCENSG00000143252.102885.361803656.69750-0.341803.428602.45140K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SDHC is not available on ENCORE database.





26 RBPs can affect the splicing of SDHC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESDHCENSG00000143252.10chr1+161326466161326630161310383161310445161332118161332984-0.107000.000040.00130excludedK562SF3B4
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.187000.000000.00000excludedK562SF3B4
SESDHCENSG00000143252.10chr1+161298185161298287161284170161284215161310383161310445-0.106000.000480.02111excludedK562PRPF8
SESDHCENSG00000143252.10chr1+161326466161326630161310383161310445161332118161332223-0.075000.000020.00037excludedK562AQR
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.067000.000270.00405excludedK562AQR
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.094000.000130.01052excludedK562EFTUD2
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.083000.001230.02663excludedK562U2AF1
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.084000.000980.03021excludedHepG2SF3A3
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.067000.000010.00109excludedHepG2SF3B4
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.069000.007190.09556excludedK562U2AF2
SESDHCENSG00000143252.10chr1+161298185161298287161293403161293460161310383161310445-0.066000.000890.04111excludedK562HNRNPK
SESDHCENSG00000143252.10chr1+1612964401612965581612934031612934601612981851612982870.118000.000000.00000includedHepG2HNRNPC
SESDHCENSG00000143252.10chr1+1612964401612965581612934031612934601612981851612982870.334000.000000.00000includedK562HNRNPC
SESDHCENSG00000143252.10chr1+1613093511613093781612981851612982871613103831613104450.054000.000730.01475includedK562HNRNPC
A3SSSDHCENSG00000143252.10chr1+1612981551612982871612981851612982871612934031612934600.163000.000000.00000longerK562AQR
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.085000.001100.035921includedK562UCHL5
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.101000.000480.040951includedHepG2UCHL5
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.116000.000000.000231includedK562XRN2
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.154000.000010.001591includedK562LIN28B
MXESDHCENSG00000143252.10chr1+1612981441612982871613103831613105571612934031612934601613321181613329790.199000.007070.047861includedK562AQR
MXESDHCENSG00000143252.10chr1+1612981551612982871613103831613105571612934031612934601613321181613329790.508000.000000.000001includedK562AQR
MXESDHCENSG00000143252.10chr1+1612981551612982871613103231613104451612934031612934601613321181613329790.425000.000000.000001includedK562AQR
MXESDHCENSG00000143252.10chr1+161298185161298287161310383161310557161293403161293460161332118161332979-0.116000.000000.000072includedK562AQR
MXESDHCENSG00000143252.10chr1+161298185161298287161310323161310445161293403161293460161332118161332979-0.188000.000000.000002includedK562AQR
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.094000.000240.017721includedHepG2BCCIP
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.133000.000470.034191includedK562LARP7
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.112000.000000.003282includedK562SMNDC1
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.101000.000060.003961includedHepG2XRN2
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.161000.000000.000001includedHepG2DDX55
MXESDHCENSG00000143252.10chr1+1612934031612934601613103831613104451612841771612842151613264661613266300.271000.000000.000011includedHepG2U2AF2
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.111000.000000.008422includedK562CSTF2T
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.199000.000030.009962includedK562AARS
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.142000.000120.013201includedK562PHF6
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.157000.000010.004172includedHepG2DDX52
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.196000.000130.007832includedK562DDX55
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.121000.000000.000161includedHepG2SUPV3L1
MXESDHCENSG00000143252.10chr1+1612934031612934601613103831613104451612841771612842151613264661613266300.093000.000010.000641includedHepG2SUPV3L1
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.087000.000390.028431includedHepG2LARP4
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.087000.000180.031021includedK562EWSR1
MXESDHCENSG00000143252.10chr1+161293403161293460161298185161298287161284170161284215161310383161310445-0.091000.001100.082782includedHepG2SSB
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.078000.000620.039411includedK562HNRNPK
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612840461612842151613103831613104450.105000.000020.001301includedK562SUPV3L1
MXESDHCENSG00000143252.10chr1+1612934031612934601612981851612982871612841701612842151613103831613104450.085000.000800.056541includedK562SERBP1
MXESDHCENSG00000143252.10chr1+161293403161293460161310383161310445161284177161284215161326466161326630-0.063000.000330.037932includedHepG2PCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SDHC is not avaliable on ENCORE database.