METAP1

General Information

Gene Name : METAP1
Gene ID : ENSG00000164024.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: METAP1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	METAP1	ENSG00000164024.11	49.29	44.77	47.03	ENCSR000AEF
HepG2	METAP1	ENSG00000164024.11	36.05	52.68	44.36	ENCSR985KAT
K562	METAP1	ENSG00000164024.11	48.25	51.93	50.09	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for METAP1 is not avaliable on ENCORE database.

Proteins bound to RNA

METAP1 RNA is bound by 31 proteins.

CanvasJS.com

eCLIP assay for METAP1 is not avaliable on ENCORE database.

31 proteins are bound to METAP1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	99983645	99983743	+	3'-UTR	3.91968	18.42968	K562	PUM2
chr4	99983816	99983937	+	3'-UTR	4.74434	16.07854	HepG2	FUBP3
chr4	99964435	99964532	+	3'-UTR,CDS	3.37324	14.17692	HepG2	BCLAF1
chr4	99955385	99955495	+	3'-UTR,CDS,intron-Proximal	3.65043	13.68298	HepG2	BCLAF1
chr4	99955339	99955422	+	3'-UTR,CDS,intron-Proximal	4.16434	13.35401	HepG2	U2AF2
chr4	99942336	99942418	+	intron-Distal	5.76407	12.50513	HepG2	HNRNPL
chr4	99956986	99957071	+	intron-Distal,intron-Proximal	4.50523	12.03011	K562	KHSRP
chr4	99916990	99917076	+	CDS,intron-Proximal	5.70860	11.80896	HepG2	PRPF8
chr4	99916869	99916972	+	5'-UTR,CDS	4.58238	11.77860	K562	DDX3X
chr4	99982270	99982342	+	CDS,intron-Proximal	4.99211	11.12698	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 88 entries

eCLIP assay for METAP1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for METAP1 is not available on ENCORE database.
136 RBPs can affect the levels of METAP1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for METAP1 is not available on ENCORE database.

136 RBPs can affect the gene expression of METAP1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
METAP1	ENSG00000164024.7	450.49000	1484.92580	-1.72080	56.75570	55.03680	HepG2	TIAL1
METAP1	ENSG00000164024.7	741.81780	1919.91230	-1.37190	50.86060	48.06650	K562	SF3A3
METAP1	ENSG00000164024.7	673.44420	1528.19460	-1.18220	41.42870	39.30900	HepG2	HNRNPU
METAP1	ENSG00000164024.7	1314.57510	2689.93610	-1.03300	39.04660	37.53470	HepG2	NELFE
METAP1	ENSG00000164024.7	4161.31390	2315.12010	0.84590	35.20080	33.24950	K562	AGGF1
METAP1	ENSG00000164024.7	708.62890	1498.20080	-1.08010	34.42340	32.70980	HepG2	TRIM56
METAP1	ENSG00000164024.7	614.78200	1474.78950	-1.26240	32.89750	31.54810	HepG2	ZNF622
METAP1	ENSG00000164024.7	1297.60580	2186.62960	-0.75290	26.50710	25.05140	HepG2	PUM1
METAP1	ENSG00000164024.7	515.42400	1512.04450	-1.55270	22.90100	20.89290	HepG2	SF3A3
METAP1	ENSG00000164024.7	623.70560	1383.03000	-1.14890	22.17430	20.64750	HepG2	HNRNPA1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 159 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for METAP1 is not available on ENCORE database.

13 RBPs can affect the splicing of METAP1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	METAP1	ENSG00000164024.7	chr4	+	99952658	99952813	99950017	99950069	99955380	99955425	0.09000	0.00000	0.00001	included	HepG2	U2AF1
SE	METAP1	ENSG00000164024.7	chr4	+	99969883	99970027	99966329	99966461	99978903	99978969	0.10400	0.00000	0.00041	included	HepG2	SFPQ
SE	METAP1	ENSG00000164024.7	chr4	+	99926919	99927017	99916890	99917018	99950017	99950069	0.05300	0.00000	0.00176	included	K562	APOBEC3C
SE	METAP1	ENSG00000164024.7	chr4	+	99926919	99927017	99916890	99917018	99950017	99950069	0.07700	0.00000	0.00001	included	K562	U2AF2
SE	METAP1	ENSG00000164024.7	chr4	+	99978903	99978969	99969883	99970027	99982304	99983964	-0.09000	0.00001	0.00037	excluded	K562	SF3B4
SE	METAP1	ENSG00000164024.7	chr4	+	99926919	99927017	99916890	99917018	99950017	99950069	0.05200	0.00001	0.00049	included	HepG2	U2AF1
SE	METAP1	ENSG00000164024.7	chr4	+	99926919	99927017	99916890	99917018	99950017	99950069	0.05300	0.00001	0.00026	included	HepG2	U2AF2
SE	METAP1	ENSG00000164024.7	chr4	+	99926919	99927017	99916890	99917018	99950017	99950069	0.07300	0.00001	0.00113	included	K562	FXR1
SE	METAP1	ENSG00000164024.7	chr4	+	99978903	99978969	99969883	99970027	99982304	99983964	-0.05700	0.00001	0.00098	excluded	K562	UTP18
SE	METAP1	ENSG00000164024.7	chr4	+	99958917	99959092	99956550	99956611	99960524	99960616	0.15000	0.00005	0.00155	included	K562	HNRNPC

Showing 1 to 10 of 19 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

METAP1

General Information

Functions

Localization

Domains (AlphaFold: METAP1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for METAP1 is not avaliable on ENCORE database.

31 proteins are bound to METAP1 RNA:

eCLIP assay for METAP1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for METAP1 is not available on ENCORE database.

136 RBPs can affect the gene expression of METAP1 :

The Knockdown/knockout RNA-Seq assay for METAP1 is not available on ENCORE database.

13 RBPs can affect the splicing of METAP1 :

The Knockdown/knockout RNA-Seq assay for METAP1 is not avaliable on ENCORE database.