MAL2

General Information

Gene Name       : MAL2
Gene ID             : ENSG00000147676.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAL2ENSG00000147676.130.000.000.00ENCSR000AEF
HepG2MAL2ENSG00000147676.1356.3463.5659.95ENCSR985KAT
K562MAL2ENSG00000147676.130.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAL2 RNA is bound by 9 proteins.  







eCLIP assay for MAL2 is not avaliable on ENCORE database.





9 proteins are bound to MAL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8120257433120257500+3'-UTR5.588007.20566HepG2IGF2BP1
chr8120257421120257503+3'-UTR4.697925.21142HepG2IGF2BP3
chr8120255927120256004+3'-UTR4.861564.46521HepG2TIA1
chr8120255926120255977+3'-UTR3.082634.09708HepG2PCBP2
chr8120256658120256722+3'-UTR4.4459010.43183HepG2IGF2BP1
chr8120256327120256405+3'-UTR4.260403.02525HepG2GRSF1
chr8120255931120256006+3'-UTR3.868886.81328HepG2TIAL1
chr8120255958120255970+3'-UTR3.156206.46362HepG2PTBP1
chr8120255924120255958+3'-UTR3.225055.86983HepG2PTBP1
chr8120220605120220693+5'-UTR,intron-Distal5.2064038.17479HepG2DDX3X
chr8120220711120220777+CDS,intron-Distal4.5902723.92760HepG2DDX3X
chr8120252451120252489+CDS4.3219011.60416HepG2IGF2BP1
chr8120252499120252547+CDS3.794243.73561HepG2IGF2BP3
chr8120252489120252500+CDS3.9496511.27814HepG2IGF2BP1
chr8120252454120252499+CDS4.017973.73561HepG2IGF2BP3
chr8120252503120252549+CDS4.000037.34809HepG2IGF2BP1
chr8120220777120220841+CDS,intron-Distal,intron-Proximal4.0330720.03640HepG2DDX3X
chr8120233824120233894+CDS,intron-Proximal4.6148210.43313HepG2DDX3X
chr8120235809120235960+intron-Distal4.384183.97018HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAL2 is not available on ENCORE database.

  • 109 RBPs can affect the levels of MAL2.  








The Knockdown/knockout RNA-Seq assay for MAL2 is not available on ENCORE database.





109 RBPs can affect the gene expression of MAL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAL2ENSG00000147676.91973.092602959.11400-0.584706.093404.75610HepG2ABCF1
MAL2ENSG00000147676.91083.026402383.80150-1.1382052.4019050.57910HepG2ACO1
MAL2ENSG00000147676.9924.922105723.04920-2.6294088.4619086.18680HepG2AKAP1
MAL2ENSG00000147676.91968.854402394.95120-0.282603.824502.93580HepG2AKAP8L
MAL2ENSG00000147676.93277.976204735.43650-0.530705.922704.79570HepG2ASCC1
MAL2ENSG00000147676.91473.921103868.62760-1.3922080.8710078.18990HepG2AUH
MAL2ENSG00000147676.91421.919201973.45980-0.472903.233302.22030HepG2BCCIP
MAL2ENSG00000147676.92278.240001714.887900.409703.566202.55160HepG2BCLAF1
MAL2ENSG00000147676.91166.087801832.45090-0.652108.656607.66830HepG2BOP1
MAL2ENSG00000147676.91975.191803218.57330-0.704402.957301.94860HepG2CCAR1
MAL2ENSG00000147676.96680.705304498.960400.570307.409006.19080HepG2CIRBP
MAL2ENSG00000147676.91842.463502383.22320-0.371307.746506.74050HepG2CKAP4
MAL2ENSG00000147676.91047.283603179.99980-1.6024015.0271013.31060HepG2CNOT7
MAL2ENSG00000147676.91741.924502437.48470-0.484705.919804.34060HepG2CPSF7
MAL2ENSG00000147676.91573.867601219.143600.368303.311302.14280HepG2CSTF2
MAL2ENSG00000147676.91471.512302904.89390-0.9812035.1473033.38170HepG2CELF1
MAL2ENSG00000147676.91600.766902028.52640-0.341704.150302.75240HepG2DDX1
MAL2ENSG00000147676.92716.784001990.966400.448305.808304.48620HepG2DDX24
MAL2ENSG00000147676.93117.089605482.44950-0.8146012.5589011.31510HepG2DDX3X
MAL2ENSG00000147676.9859.064501940.26580-1.1754017.4505015.75090HepG2DDX55
MAL2ENSG00000147676.92142.004202691.60190-0.329502.725801.72080HepG2DDX5
MAL2ENSG00000147676.93210.731804709.06340-0.552505.401804.56460HepG2DDX6
MAL2ENSG00000147676.94615.620302280.636501.0170049.0893047.16080HepG2DKC1
MAL2ENSG00000147676.91625.239201971.49890-0.278604.414303.62470HepG2DNAJC2
MAL2ENSG00000147676.93559.348104527.40750-0.347102.790702.19450HepG2EIF2S1
MAL2ENSG00000147676.9909.142101978.57100-1.121908.180706.70000HepG2EIF3D
MAL2ENSG00000147676.94350.778003081.513300.4975012.4886010.96510HepG2EIF4G1
MAL2ENSG00000147676.93387.635102563.717000.401904.379703.03420HepG2ESF1
MAL2ENSG00000147676.95319.834004441.807800.260104.328703.60590HepG2ETF1
MAL2ENSG00000147676.91824.471802329.34650-0.352403.614902.65980HepG2EWSR1
MAL2ENSG00000147676.91244.854201767.97590-0.506103.254901.97470HepG2FAM120A
MAL2ENSG00000147676.91354.929102988.11540-1.1410019.1701017.46980HepG2FIP1L1
MAL2ENSG00000147676.91963.965902977.68980-0.600402.832301.70600HepG2FUS
MAL2ENSG00000147676.92550.184405047.67850-0.9850018.3850016.78090HepG2FXR1
MAL2ENSG00000147676.91550.785704682.82430-1.5944039.4804037.09750HepG2G3BP1
MAL2ENSG00000147676.91256.544402247.64280-0.8390011.490209.39600HepG2GNB2L1
MAL2ENSG00000147676.91462.111602943.37340-1.009408.275706.36950HepG2GRSF1
MAL2ENSG00000147676.91725.784702275.81150-0.399105.358204.04560HepG2HDGF
MAL2ENSG00000147676.91868.050902851.37330-0.610103.330301.79380HepG2HLTF
MAL2ENSG00000147676.92950.267902008.147300.554903.004102.33340HepG2HNRNPA1
MAL2ENSG00000147676.91371.785302233.68320-0.7034010.860109.56520HepG2HNRNPC
MAL2ENSG00000147676.92442.379102113.077400.208802.293501.63650HepG2HNRNPF
MAL2ENSG00000147676.92188.653404740.93790-1.1151026.9243024.97390HepG2HNRNPK
MAL2ENSG00000147676.93186.866901819.986900.8081012.9327011.70380HepG2HNRNPLL
MAL2ENSG00000147676.91282.789402062.00560-0.6848010.980209.31500HepG2HNRNPM
MAL2ENSG00000147676.92748.439702080.774600.401404.769403.84310HepG2IGF2BP1
MAL2ENSG00000147676.92042.321404760.11750-1.2208027.1093025.25800HepG2IGF2BP2
MAL2ENSG00000147676.91057.006104466.64560-2.0792019.3188016.98700HepG2IGF2BP3
MAL2ENSG00000147676.91577.542402266.55100-0.5228014.9150013.36760HepG2ILF2
MAL2ENSG00000147676.93432.451504787.62370-0.480103.555402.40120HepG2KHSRP
MAL2ENSG00000147676.91773.006102201.80760-0.312502.479401.40990HepG2LARP7
MAL2ENSG00000147676.92243.374605049.43760-1.1705024.2514022.43040HepG2MAGOH
MAL2ENSG00000147676.92103.942605077.81080-1.2711025.1987023.45960HepG2MATR3
MAL2ENSG00000147676.91143.962102070.88740-0.856205.092303.69110HepG2METAP2
MAL2ENSG00000147676.91920.468002418.91610-0.332903.032002.18570HepG2MSI2
MAL2ENSG00000147676.93294.336401855.984400.827707.501705.87520HepG2MTPAP
MAL2ENSG00000147676.91769.647205197.51280-1.5544039.1039036.92600HepG2NCBP2
MAL2ENSG00000147676.92539.380503097.33790-0.286603.393402.55100HepG2NOL12
MAL2ENSG00000147676.9602.456701781.39140-1.5641016.2188013.45050HepG2NONO
MAL2ENSG00000147676.91455.310502905.88100-0.997607.459905.95130HepG2PABPC1
MAL2ENSG00000147676.93084.195904629.14250-0.585906.742505.62280HepG2PABPC4
MAL2ENSG00000147676.91306.484602196.35880-0.7494020.8053018.91410HepG2PARN
MAL2ENSG00000147676.93916.201204425.72150-0.176502.245901.68880HepG2PCBP1
MAL2ENSG00000147676.91625.026202191.90550-0.431707.814706.59720HepG2PRPF4
MAL2ENSG00000147676.92276.673004503.25300-0.9840044.3204042.68700HepG2PTBP1
MAL2ENSG00000147676.94334.007702956.648300.551608.542007.57100HepG2PUF60
MAL2ENSG00000147676.91913.319703138.57530-0.7140030.5294028.98740HepG2PUM1
MAL2ENSG00000147676.92164.045302428.04760-0.166101.846701.32200HepG2PUS1
MAL2ENSG00000147676.92661.894204877.31330-0.8736028.2092026.52640HepG2QKI
MAL2ENSG00000147676.9717.929102721.03880-1.9222012.0945010.70060HepG2RAVER1
MAL2ENSG00000147676.92344.362903069.38150-0.388802.194001.41960HepG2RBM15
MAL2ENSG00000147676.91464.470103712.50740-1.3420063.7274061.88780HepG2RBM22
MAL2ENSG00000147676.93042.416104426.40770-0.540909.089007.92360HepG2RBM25
MAL2ENSG00000147676.91837.732702654.98440-0.530805.643304.21190HepG2RBM27
MAL2ENSG00000147676.93016.547705011.75810-0.7324027.8331026.48530HepG2NELFE
MAL2ENSG00000147676.93482.730804667.64490-0.4225010.317109.24310HepG2RECQL
MAL2ENSG00000147676.9749.180501925.05920-1.3615012.4623011.27110HepG2RPS19
MAL2ENSG00000147676.91418.644202499.48460-0.8171012.2587010.03600HepG2RPS5
MAL2ENSG00000147676.9961.861501480.93050-0.622605.291404.23690HepG2RRP9
MAL2ENSG00000147676.92388.469901976.048500.273404.255303.48650HepG2SAFB2
MAL2ENSG00000147676.9839.400102226.66590-1.407504.910103.00050HepG2SF1
MAL2ENSG00000147676.93761.164403002.969800.324701.881601.32340HepG2SF3A3
MAL2ENSG00000147676.92549.742701801.471300.501105.902404.90490HepG2SF3B1
MAL2ENSG00000147676.93932.289504688.61840-0.253804.247503.53970HepG2SF3B4
MAL2ENSG00000147676.9655.967902157.86410-1.717906.452904.04680HepG2SFPQ
MAL2ENSG00000147676.93421.169602834.888100.271105.108304.20110HepG2SLBP
MAL2ENSG00000147676.91444.387102304.41580-0.6739023.5504021.97130HepG2SMN1
MAL2ENSG00000147676.9939.663102004.43700-1.093002.748201.96990HepG2SNRNP70
MAL2ENSG00000147676.93377.743004193.10150-0.312006.173405.50690HepG2SRFBP1
MAL2ENSG00000147676.94015.060204893.84100-0.285505.761305.14090HepG2SRSF1
MAL2ENSG00000147676.92474.091802919.21470-0.238703.212002.54570HepG2SRSF5
MAL2ENSG00000147676.92384.854802076.040500.200002.159201.53590HepG2SRSF7
MAL2ENSG00000147676.93203.663703981.34730-0.313506.271005.49960HepG2SRSF9
MAL2ENSG00000147676.92108.745102775.35770-0.396302.538001.49060HepG2STIP1
MAL2ENSG00000147676.92151.399503319.98970-0.6259022.0330020.55130HepG2SUCLG1
MAL2ENSG00000147676.9661.312601931.59180-1.5464029.6112027.83050HepG2SUPV3L1
MAL2ENSG00000147676.93536.292804398.60440-0.314804.964204.24800HepG2TAF15
MAL2ENSG00000147676.93028.797001773.722700.7719013.1472011.74990HepG2TARDBP
MAL2ENSG00000147676.91246.969802156.12690-0.7900017.2302016.17630HepG2TIAL1
MAL2ENSG00000147676.91155.848102175.36320-0.9123031.3816029.73500HepG2TRIM56
MAL2ENSG00000147676.91974.482102556.44090-0.372703.045102.38740HepG2U2AF1
MAL2ENSG00000147676.9987.636702315.34460-1.229203.932702.74440HepG2U2AF2
MAL2ENSG00000147676.91623.939403057.34840-0.9128013.7059011.79870HepG2UBE2L3
MAL2ENSG00000147676.9433.754801141.11030-1.3955024.4727022.33340HepG2UCHL5
MAL2ENSG00000147676.92157.856102663.17710-0.303504.887004.00080HepG2UPF1
MAL2ENSG00000147676.91875.837402737.35850-0.5452012.2298010.23540HepG2UTP18
MAL2ENSG00000147676.91135.408902571.18980-1.1792053.5756051.46610HepG2UTP3
MAL2ENSG00000147676.91734.289302163.16030-0.318805.541504.64280HepG2ZC3H8
MAL2ENSG00000147676.92097.599802928.98220-0.4817014.4482013.44110HepG2ZNF622
MAL2ENSG00000147676.90.000006.31030-99999.999991.912301.30730K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAL2 is not available on ENCORE database.





3 RBPs can affect the splicing of MAL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAL2ENSG00000147676.9chr8+120233826120233997120220609120220844120252404120252560-0.112000.000000.00000excludedHepG2U2AF1
SEMAL2ENSG00000147676.9chr8+120233826120233997120220778120220844120252404120252560-0.119000.000020.00038excludedHepG2U2AF2
SEMAL2ENSG00000147676.9chr8+1202212601202214401202207781202208441202338261202339970.083000.001790.06944includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAL2 is not avaliable on ENCORE database.