ERAL1

General Information

Gene Name       : ERAL1
Gene ID             : ENSG00000132591.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ERAL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ERAL1ENSG00000132591.1163.8965.6464.77ENCSR000AEF
HepG2ERAL1ENSG00000132591.1184.4578.2081.33ENCSR985KAT
K562ERAL1ENSG00000132591.11103.33100.43101.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
ERAL1K562CRISPRERAL1-BGKcLV40-27,ERAL1-BGKcLV40-28NT-BGKcLV40-1,NT-BGKcLV40-258.7,65.4SubmittingENCORE2
ERAL1HepG2CRISPRBGHcLV41-47,BGHcLV41-48BGHcLV41-1,BGHcLV41-20.0,0.0NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ERAL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ERAL1 RNA is bound by 12 proteins.  







eCLIP assay for ERAL1 is not avaliable on ENCORE database.





12 proteins are bound to ERAL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr172718785927187884+3'-UTR4.4863519.07630K562YBX3
chr172718495627184971+3'-UTR,CDS,intron-Distal,intron-Proximal3.620625.95764K562YBX3
chr172718769527187882+3'-UTR5.311269.16654HepG2UPF1
chr172718789627187948+3'-UTR3.878664.87320K562UPF1
chr172718793027188001+3'-UTR5.4030110.97360K562YBX3
chr172718513527185188+3'-UTR,CDS,intron-Proximal4.776724.40745K562SF3B4
chr172718608627186132+3'-UTR,CDS,intron-Proximal3.947834.33997K562PUM2
chr172718784927187859+3'-UTR4.5429122.13539K562YBX3
chr172718793327187999+3'-UTR3.802723.19668HepG2UPF1
chr172718532927185393+3'-UTR,CDS,intron-Proximal5.675406.39134HepG2SF3A3
chr172718796627188059+3'-UTR4.4249011.15355HepG2PCBP2
chr172718741527187458+3'-UTR,CDS,intron-Distal,intron-Proximal3.942344.89208K562AQR
chr172718607227186086+3'-UTR,CDS4.385874.48692K562YBX3
chr172718796627188049+3'-UTR3.437594.48159HepG2LARP4
chr172718772527187823+3'-UTR3.002623.80905K562UPF1
chr172718608627186115+3'-UTR,CDS3.722665.73361K562YBX3
chr172718553227185624+3'-UTR,CDS,intron-Distal,intron-Proximal4.544863.93512K562SMNDC1
chr172718788427187917+3'-UTR4.4038918.08646K562YBX3
chr172718745327187465+3'-UTR,CDS,intron-Distal3.196623.90824K562YBX3
chr172718576527185817+3'-UTR,CDS,intron-Distal3.126903.24162HepG2G3BP1
chr172718621827186260+3'-UTR,CDS,intron-Proximal3.409254.98507K562PUM2
chr172718203627182104+5'-UTR,CDS3.9827118.27108K562DDX3X
chr172718363427183642+5'-UTR,intron-Proximal3.227153.94787K562AQR
chr172718360627183634+5'-UTR,CDS,intron-Proximal3.268383.94787K562AQR
chr172718360027183606+CDS,intron-Proximal4.538673.62536K562AQR
chr172718216827182233+CDS3.771984.00968HepG2DDX3X
chr172718502327185129+intron-Distal,intron-Proximal3.638634.28282K562EFTUD2
chr172718630127186345+intron-Proximal4.060864.98250K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ERAL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ERAL1 is not available on ENCORE database.

  • 92 RBPs can affect the levels of ERAL1.  








The Knockdown/knockout RNA-Seq assay for ERAL1 is not available on ENCORE database.





92 RBPs can affect the gene expression of ERAL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ERAL1ENSG00000132591.7642.89300946.73140-0.558404.977203.69330HepG2ADAR
ERAL1ENSG00000132591.7998.936401190.64390-0.253302.405501.68440HepG2AKAP8L
ERAL1ENSG00000132591.7801.904601098.94280-0.454603.420802.42470HepG2BCLAF1
ERAL1ENSG00000132591.71068.49780874.528400.288901.825801.33040HepG2BOP1
ERAL1ENSG00000132591.7976.712601327.34740-0.442503.530702.66430HepG2CIRBP
ERAL1ENSG00000132591.71024.430601184.80020-0.209802.024801.44330HepG2CKAP4
ERAL1ENSG00000132591.71087.51380787.473200.465602.245101.56060HepG2CNOT7
ERAL1ENSG00000132591.7518.41020802.84500-0.631005.562004.61870HepG2CPSF6
ERAL1ENSG00000132591.71189.365501617.46680-0.443506.364305.46570HepG2CELF1
ERAL1ENSG00000132591.7800.12380992.91780-0.311502.106301.50540HepG2DDX21
ERAL1ENSG00000132591.7743.640101243.67140-0.741907.738406.52320HepG2DDX55
ERAL1ENSG00000132591.72012.762401476.030000.447403.353302.65070HepG2EIF4A3
ERAL1ENSG00000132591.7454.808101437.21860-1.6599024.7008022.80650HepG2EIF4B
ERAL1ENSG00000132591.71472.096101715.78670-0.221002.120501.37160HepG2EIF4G1
ERAL1ENSG00000132591.71587.381502301.23390-0.5358012.1512011.03750HepG2ETF1
ERAL1ENSG00000132591.7938.133401293.77080-0.463703.060402.25490HepG2FIP1L1
ERAL1ENSG00000132591.7732.895601035.09840-0.498104.242802.69640HepG2FKBP4
ERAL1ENSG00000132591.7462.81110804.26210-0.797203.141102.05720HepG2FTO
ERAL1ENSG00000132591.7737.78520941.48190-0.351702.685801.91140HepG2FUBP3
ERAL1ENSG00000132591.7828.537601381.56130-0.737707.820006.73150HepG2G3BP1
ERAL1ENSG00000132591.7654.944301051.63500-0.683206.879705.26030HepG2GNB2L1
ERAL1ENSG00000132591.71301.286501598.29800-0.296602.911701.95630HepG2HNRNPA2B1
ERAL1ENSG00000132591.71054.287101399.14350-0.408303.360102.59360HepG2HNRNPK
ERAL1ENSG00000132591.71326.809101584.10780-0.255703.087902.37870HepG2HNRNPL
ERAL1ENSG00000132591.7588.12690868.46660-0.562304.625103.83280HepG2HNRNPLL
ERAL1ENSG00000132591.7748.887701412.53750-0.915509.192907.26510HepG2KHSRP
ERAL1ENSG00000132591.7782.276101047.04010-0.420603.727402.79120HepG2MSI2
ERAL1ENSG00000132591.7761.015801142.31380-0.586003.136601.96850HepG2NONO
ERAL1ENSG00000132591.7535.96700770.10090-0.522903.969003.07870HepG2NSUN2
ERAL1ENSG00000132591.7260.026001052.70980-2.0174064.4365061.57620HepG2PARN
ERAL1ENSG00000132591.7735.25060948.54790-0.367503.607302.77680HepG2PPIL4
ERAL1ENSG00000132591.7602.26630959.07310-0.671206.652605.46130HepG2PRPF8
ERAL1ENSG00000132591.71220.437501552.44970-0.347104.256303.60980HepG2PTBP1
ERAL1ENSG00000132591.71376.539101747.52120-0.344304.649303.92310HepG2PUM1
ERAL1ENSG00000132591.71362.342801746.22050-0.358103.710702.93960HepG2PUM2
ERAL1ENSG00000132591.71127.518601681.28610-0.576409.054008.02250HepG2QKI
ERAL1ENSG00000132591.71520.760201923.39540-0.338904.067203.47010HepG2RBM22
ERAL1ENSG00000132591.71070.003501525.89610-0.512006.098605.13330HepG2RBM25
ERAL1ENSG00000132591.7977.849301242.53830-0.345602.611201.64850HepG2RBM27
ERAL1ENSG00000132591.71383.294101727.70590-0.320704.046103.41450HepG2NELFE
ERAL1ENSG00000132591.71217.779101609.16240-0.402105.838904.98730HepG2RECQL
ERAL1ENSG00000132591.7484.75340948.69050-0.9687011.162909.74950HepG2RRP9
ERAL1ENSG00000132591.71477.423401120.202900.399202.359001.73750HepG2SF3A3
ERAL1ENSG00000132591.71166.000801616.25400-0.471107.581906.68160HepG2SF3B4
ERAL1ENSG00000132591.71172.896401578.50060-0.428507.461406.39470HepG2SLBP
ERAL1ENSG00000132591.7889.238801104.51240-0.312803.841403.10370HepG2SMN1
ERAL1ENSG00000132591.71809.168102172.38610-0.264003.699103.14560HepG2SRFBP1
ERAL1ENSG00000132591.71123.015301625.39990-0.533409.569608.49880HepG2SRSF5
ERAL1ENSG00000132591.7803.883201372.51190-0.7718018.6457017.44570HepG2SRSF9
ERAL1ENSG00000132591.71646.149201886.11360-0.196302.092501.63040HepG2SSB
ERAL1ENSG00000132591.7670.32790990.60950-0.563404.435402.84130HepG2SSRP1
ERAL1ENSG00000132591.7577.798501237.96320-1.0993015.3936014.02630HepG2SUPV3L1
ERAL1ENSG00000132591.71195.380301516.42850-0.343203.716203.08240HepG2TAF15
ERAL1ENSG00000132591.7680.53630846.62910-0.315101.954401.33150HepG2TARDBP
ERAL1ENSG00000132591.7599.76110829.70700-0.468203.761402.61850HepG2TFIP11
ERAL1ENSG00000132591.71041.120601393.33530-0.420404.432903.38190HepG2TIA1
ERAL1ENSG00000132591.7665.070101033.50350-0.636007.534006.78340HepG2TIAL1
ERAL1ENSG00000132591.7864.943701042.60160-0.269502.583402.03420HepG2TRIM56
ERAL1ENSG00000132591.71095.904101608.30220-0.553407.057205.55500HepG2TUFM
ERAL1ENSG00000132591.7676.277901106.70640-0.710607.338406.32170HepG2U2AF1
ERAL1ENSG00000132591.71223.426901702.40450-0.476603.577602.61960HepG2UBE2L3
ERAL1ENSG00000132591.7554.86000731.23980-0.398202.715701.96290HepG2UCHL5
ERAL1ENSG00000132591.7848.21900993.45080-0.228001.933801.33230HepG2UPF1
ERAL1ENSG00000132591.71208.67880959.134500.333502.782902.18460HepG2UTP3
ERAL1ENSG00000132591.7862.259601195.38200-0.471307.647806.62090HepG2ZC3H8
ERAL1ENSG00000132591.72435.268901947.964900.322004.606403.90650K562AGGF1
ERAL1ENSG00000132591.71355.665401640.70580-0.275303.440902.36510K562BCLAF1
ERAL1ENSG00000132591.7823.114101099.90760-0.418203.266402.10170K562CCAR1
ERAL1ENSG00000132591.7913.366601215.67190-0.412504.030303.08440K562CPSF6
ERAL1ENSG00000132591.7978.539201244.72000-0.347103.434202.23620K562CSTF2
ERAL1ENSG00000132591.72641.014703855.16990-0.5457010.606808.76560K562CELF1
ERAL1ENSG00000132591.72479.143002040.551700.280803.916103.15980K562DDX47
ERAL1ENSG00000132591.7912.225501231.28230-0.432703.485901.97210K562DHX30
ERAL1ENSG00000132591.7838.632001182.79840-0.496104.719502.94310K562DNAJC21
ERAL1ENSG00000132591.71435.601301135.135700.338703.776002.85610K562EIF3G
ERAL1ENSG00000132591.71746.605401257.497500.473905.136504.01680K562EIF4A3
ERAL1ENSG00000132591.71387.039801097.666000.337503.150101.75770K562EWSR1
ERAL1ENSG00000132591.71383.871901849.55320-0.418504.691102.99350K562EXOSC5
ERAL1ENSG00000132591.7951.637601236.84060-0.378202.862801.99300K562FMR1
ERAL1ENSG00000132591.7668.057701048.30070-0.650006.187604.76670K562FTO
ERAL1ENSG00000132591.72033.116401307.744200.6365013.5980012.35930K562FXR1
ERAL1ENSG00000132591.7554.819001014.68980-0.870908.105206.76930K562G3BP2
ERAL1ENSG00000132591.71267.045001651.00740-0.381904.660303.18730K562GLRX3
ERAL1ENSG00000132591.7893.905201160.69920-0.376802.583501.81480K562GPKOW
ERAL1ENSG00000132591.71746.756502176.13630-0.317103.093001.95650K562HNRNPA1
ERAL1ENSG00000132591.7854.580701569.78030-0.8773015.6318014.29680K562HNRNPC
ERAL1ENSG00000132591.71743.129701251.069700.478402.520201.63450K562HNRNPM
ERAL1ENSG00000132591.72033.103702410.05930-0.245402.243701.43880K562HNRNPU
ERAL1ENSG00000132591.7790.891701110.64570-0.489803.739602.01670K562KHDRBS1
ERAL1ENSG00000132591.7634.07570991.00930-0.644204.687703.43340K562KRR1
ERAL1ENSG00000132591.71450.042801735.83080-0.259503.042602.19680K562MTPAP
ERAL1ENSG00000132591.71396.244601928.59710-0.4660011.147709.78850K562NSUN2
ERAL1ENSG00000132591.7490.908101102.58080-1.167409.593905.94480K562PARN
ERAL1ENSG00000132591.71850.943301370.359400.433603.849002.96520K562PRPF8
ERAL1ENSG00000132591.72137.939201510.050800.501504.356303.54070K562PTBP1
ERAL1ENSG00000132591.72646.704402010.430500.396603.616903.00800K562PUS1
ERAL1ENSG00000132591.7851.134301103.75070-0.375002.289501.41390K562SF3B1
ERAL1ENSG00000132591.7830.940701211.55270-0.544005.484103.67900K562SLBP
ERAL1ENSG00000132591.71277.544401626.51150-0.348403.014301.79060K562SRSF7
ERAL1ENSG00000132591.71575.427402053.97880-0.382704.426102.47970K562SRSF9
ERAL1ENSG00000132591.7986.796501326.56030-0.426903.128502.04770K562SUPV3L1
ERAL1ENSG00000132591.72270.072301810.007100.326603.515702.59000K562SYNCRIP
ERAL1ENSG00000132591.7845.331001015.42520-0.264501.995901.31430K562U2AF2
ERAL1ENSG00000132591.71036.152301404.12270-0.438403.727702.52950K562UCHL5
ERAL1ENSG00000132591.71383.038701749.78000-0.339303.214102.27550K562WDR3
ERAL1ENSG00000132591.72135.183603029.62350-0.504806.573305.15360K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ERAL1 is not available on ENCORE database.





11 RBPs can affect the splicing of ERAL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEERAL1ENSG00000132591.7chr17+271855932718565127185391271855042718598127186131-0.107000.000480.01148excludedK562SRSF1
SEERAL1ENSG00000132591.7chr17+271855932718584227185055271855042718598127186131-0.056000.000020.00183excludedK562PRPF8
SEERAL1ENSG00000132591.7chr17+271855932718565127185391271855042718598127186131-0.101000.001100.05471excludedK562EFTUD2
SEERAL1ENSG00000132591.7chr17+271851632718522527183522271836002718539127185413-0.105000.000430.00997excludedK562U2AF2
A3SSERAL1ENSG00000132591.7chr17+2718595227186131271859812718613127185593271858420.065000.000000.00000longerK562AQR
A3SSERAL1ENSG00000132591.7chr17+2718490727185003271849562718500327183503271836000.069000.000000.00000longerK562AQR
A5SSERAL1ENSG00000132591.7chr17+2718352227183703271835222718360027184956271850030.110000.000280.07831longerHepG2SUPV3L1
A5SSERAL1ENSG00000132591.7chr17+2718352227183703271835222718360027184956271850030.115000.001300.04787longerK562PUS1
A5SSERAL1ENSG00000132591.7chr17+2718352227183703271835222718360027184956271849900.193000.000000.00000longerK562AQR
A5SSERAL1ENSG00000132591.7chr17+2718352227183703271835222718360027184956271850030.114000.000060.02657longerHepG2BCCIP
A5SSERAL1ENSG00000132591.7chr17+2718352227183703271835222718360027184956271850030.112000.000020.01631longerHepG2XRN2
MXEERAL1ENSG00000132591.7chr17+2718539127185504271855932718584227185163271852252718598127186131-0.109000.002140.026582includedHepG2SFPQ
MXEERAL1ENSG00000132591.7chr17+2718539127185504271855932718584227185163271852252718598127186131-0.144000.000010.000462includedHepG2HNRNPUL1
MXEERAL1ENSG00000132591.7chr17+27185391271855042718559327185842271849562718500327185981271861310.051000.000020.001201includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ERAL1 is not avaliable on ENCORE database.