C2ORF15

General Information

Gene Name       : C2ORF15
Gene ID             : ENSG00000273045.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C2ORF15)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C2ORF15ENSG00000273045.61.302.141.72ENCSR000AEF
HepG2C2ORF15ENSG00000273045.62.404.483.44ENCSR985KAT
K562C2ORF15ENSG00000273045.60.040.100.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C2ORF15 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C2ORF15 RNA is bound by 14 proteins.  







eCLIP assay for C2ORF15 is not avaliable on ENCORE database.





14 proteins are bound to C2ORF15 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr29981375199813766+3'-UTR,intron-Distal3.148178.87920K562YBX3
chr29981245699812527+3'-UTR,intron-Distal,intron-Proximal6.1540429.67392HepG2UPF1
chr29981232399812346+3'-UTR,intron-Distal,intron-Proximal3.584376.67761K562UPF1
chr29981361199813626+3'-UTR,intron-Distal4.7772815.52312K562UPF1
chr29981392199813979+3'-UTR,intron-Distal3.312614.01563K562LIN28B
chr29981234699812377+3'-UTR,intron-Distal,intron-Proximal4.4773812.41920K562UPF1
chr29981371899813751+3'-UTR,intron-Distal3.4942711.95636K562YBX3
chr29981238199812437+3'-UTR,intron-Distal,intron-Proximal5.6724915.43167K562AKAP1
chr29981376199813817+3'-UTR,intron-Distal3.225048.85201K562FAM120A
chr29981352199813538+3'-UTR,intron-Distal4.167937.13820K562UPF1
chr29981276899812851+3'-UTR,intron-Distal,intron-Proximal4.8039424.07611K562UPF1
chr29981299199813044+3'-UTR,intron-Distal,intron-Proximal4.1800314.85633K562AKAP1
chr29981263799812689+3'-UTR,intron-Distal3.6450313.42347K562UPF1
chr29981381099813865+3'-UTR,intron-Distal5.8192510.71230HepG2SUB1
chr29981278099812884+3'-UTR,intron-Distal,intron-Proximal5.1625422.63930HepG2UPF1
chr29981362699813674+3'-UTR,intron-Distal4.6556517.70314K562UPF1
chr29981227299812302+3'-UTR,intron-Proximal3.8441917.66615K562UPF1
chr29981225599812272+3'-UTR,intron-Proximal3.9407217.36540K562UPF1
chr29981374599813812+3'-UTR,intron-Distal5.2164335.74499K562UPF1
chr29981225499812321+3'-UTR,intron-Distal,intron-Proximal4.961135.97422HepG2AKAP1
chr29981263799812685+3'-UTR,intron-Distal3.485885.00403K562IGF2BP1
chr29981299599813070+3'-UTR,intron-Distal,intron-Proximal4.8776425.28982K562UPF1
chr29981238899812456+3'-UTR,intron-Distal6.6358533.27376HepG2UPF1
chr29981288899812929+3'-UTR,intron-Distal,intron-Proximal5.1666214.07248K562UPF1
chr29981299199813038+3'-UTR,intron-Distal,intron-Proximal5.5913810.01142HepG2UPF1
chr29981371499813745+3'-UTR,intron-Distal4.4976716.54613K562UPF1
chr29981294399812993+3'-UTR,intron-Distal,intron-Proximal4.2368520.23985K562UPF1
chr29981294099812989+3'-UTR,intron-Distal,intron-Proximal4.0502619.94558K562AKAP1
chr29981247399812524+3'-UTR,intron-Distal,intron-Proximal4.1487917.37748K562AKAP1
chr29981248099812556+3'-UTR,intron-Distal,intron-Proximal5.2993123.55935K562UPF1
chr29981295399812991+3'-UTR,intron-Distal,intron-Proximal4.691539.06961HepG2UPF1
chr29981381299813862+3'-UTR,intron-Distal4.4069516.22320K562UPF1
chr29981224599812310+3'-UTR,intron-Proximal4.4696024.28812HepG2UPF1
chr29981263899812697+3'-UTR,intron-Distal3.794188.96355K562FAM120A
chr29981308699813160+3'-UTR,intron-Distal5.3955932.67532K562UPF1
chr29979768599797758+5'-UTR,intron-Distal,intron-Proximal4.5385411.95020HepG2PRPF8
chr29980263999802671+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.1451515.56247K562DDX3X
chr29979764999797713+5'-UTR,intron-Distal,intron-Proximal3.7996413.18532K562DDX3X
chr29981133799811360+CDS4.241303.89826HepG2BCLAF1
chr29981133299811361+CDS,intron-Proximal3.002303.84692K562UCHL5
chr29980267999802747+CDS,intron-Distal,intron-Proximal4.891224.02817HepG2PRPF8
chr29981157899811617+CDS,intron-Proximal3.673844.17155HepG2BCLAF1
chr29977507999775139+intron-Distal4.439563.16986HepG2QKI
chr29977395099774016+intron-Distal4.082983.63454HepG2SUGP2
chr29977425899774335+intron-Distal3.127733.10883HepG2SUGP2
chr29980474399804889+intron-Distal,intron-Proximal3.466224.13575K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C2ORF15 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C2ORF15 is not available on ENCORE database.

  • 119 RBPs can affect the levels of C2ORF15.  








The Knockdown/knockout RNA-Seq assay for C2ORF15 is not available on ENCORE database.





119 RBPs can affect the gene expression of C2ORF15 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C2orf15ENSG00000241962.51336.489402098.11480-0.650606.192205.43240HepG2AKAP1
C2ORF15ENSG00000273045.147.11980101.72620-1.110304.305403.36390HepG2AKAP8L
C2orf15ENSG00000241962.51366.960401736.02500-0.344802.426201.68560HepG2ASCC1
C2orf15ENSG00000241962.51535.566501914.62700-0.318303.430302.68090HepG2AUH
C2orf15ENSG00000241962.5872.723301368.79180-0.649305.353804.03850HepG2BCCIP
C2orf15ENSG00000241962.5766.870001189.42310-0.633205.679804.44000HepG2BCLAF1
C2orf15ENSG00000241962.5632.07020903.13920-0.514904.928403.30600HepG2BUD13
C2orf15ENSG00000241962.51249.051901649.33970-0.401103.167902.34230HepG2CIRBP
C2ORF15ENSG00000273045.1277.43930163.623500.761704.073803.14560HepG2CIRBP
C2orf15ENSG00000241962.51375.580301064.526600.369705.631704.74440HepG2CKAP4
C2ORF15ENSG00000273045.159.90070111.80180-0.900302.791001.68220HepG2CPSF7
C2ORF15ENSG00000273045.190.2906048.660000.891702.489001.46520HepG2CSTF2
C2orf15ENSG00000241962.51164.323201607.74870-0.465604.509103.59910HepG2DAZAP1
C2ORF15ENSG00000273045.1158.4462091.469600.792503.200302.47440HepG2DDX21
C2orf15ENSG00000241962.51297.20950925.665000.486705.374004.09450HepG2DDX24
C2ORF15ENSG00000273045.1172.9672089.559900.949504.588903.40150HepG2DDX24
C2orf15ENSG00000241962.5925.675502009.85920-1.1185018.8814017.40090HepG2DDX3X
C2ORF15ENSG00000273045.1299.10960199.382700.585002.735802.11190HepG2DDX3X
C2orf15ENSG00000241962.51043.073001345.78060-0.367602.028701.35620HepG2DDX55
C2orf15ENSG00000241962.5527.78940806.38200-0.611502.775301.79500HepG2DDX59
C2orf15ENSG00000241962.5877.531701726.45420-0.9763012.5053011.30570HepG2DDX6
C2ORF15ENSG00000273045.1107.64810171.29120-0.670102.282101.71590HepG2DDX6
C2orf15ENSG00000241962.5935.211001157.51150-0.307702.936402.21560HepG2DNAJC21
C2orf15ENSG00000241962.5932.298101147.37400-0.299503.622802.89500HepG2DNAJC2
C2orf15ENSG00000241962.5838.415301659.73830-0.9852014.3889013.10740HepG2EIF2S1
C2orf15ENSG00000241962.5840.550001834.23300-1.1258016.7244015.15940HepG2EIF4A3
C2ORF15ENSG00000273045.191.69570181.94840-0.988604.534103.71900HepG2EIF4A3
C2ORF15ENSG00000273045.174.34110177.16820-1.252905.402404.46350HepG2EIF4B
C2orf15ENSG00000241962.51982.722001586.013100.322004.133803.14970HepG2EIF4G1
C2orf15ENSG00000241962.51105.254601519.32230-0.459004.451503.43390HepG2EIF4G2
C2ORF15ENSG00000273045.1186.57680115.342400.693702.821102.00070HepG2EIF4G2
C2ORF15ENSG00000273045.1185.98960117.588500.661402.661701.58990HepG2ESF1
C2orf15ENSG00000241962.51142.898902198.42700-0.9438015.9377014.68970HepG2ETF1
C2orf15ENSG00000241962.5667.017201040.46540-0.641405.328904.17040HepG2EWSR1
C2orf15ENSG00000241962.5542.00740688.92370-0.346002.525501.41020HepG2FAM120A
C2orf15ENSG00000241962.5777.972501120.19330-0.526004.105102.58180HepG2FKBP4
C2orf15ENSG00000241962.5376.82820711.31960-0.916603.862902.66160HepG2FTO
C2orf15ENSG00000241962.51146.119401850.58230-0.691208.074106.93880HepG2FXR1
C2ORF15ENSG00000273045.1102.54300183.60350-0.840403.657702.87030HepG2FXR1
C2orf15ENSG00000241962.5856.037601716.72960-1.0039014.2607012.80820HepG2G3BP1
C2orf15ENSG00000241962.5616.00590804.97770-0.386002.145001.57760HepG2GPKOW
C2ORF15ENSG00000273045.1291.23320122.032601.254808.856307.75430HepG2GPKOW
C2orf15ENSG00000241962.51235.998401477.49450-0.257502.675201.75350HepG2HNRNPA2B1
C2ORF15ENSG00000273045.1176.57080112.167500.654502.791701.85500HepG2HNRNPA2B1
C2orf15ENSG00000241962.5481.184001299.88120-1.4337030.6779028.66550HepG2HNRNPC
C2orf15ENSG00000241962.5843.701701290.90750-0.613605.491904.52350HepG2HNRNPF
C2ORF15ENSG00000273045.198.13900172.48110-0.813503.222702.47030HepG2HNRNPK
C2orf15ENSG00000241962.5911.352801464.58160-0.6844017.7542016.18210HepG2HNRNPL
C2orf15ENSG00000241962.5876.408901291.28510-0.559109.849208.76150HepG2HNRNPU
C2orf15ENSG00000241962.5816.451501271.18620-0.638703.888303.04130HepG2IGF2BP1
C2orf15ENSG00000241962.5820.501901745.03340-1.0887018.0887016.53980HepG2IGF2BP2
C2ORF15ENSG00000273045.192.17290173.10750-0.909304.002203.20380HepG2IGF2BP2
C2orf15ENSG00000241962.51062.787301319.00020-0.311604.609803.68290HepG2ILF2
C2ORF15ENSG00000273045.1163.3544094.560800.788604.185503.30210HepG2ILF2
C2orf15ENSG00000241962.51327.640701755.17680-0.402802.361301.44610HepG2KHSRP
C2orf15ENSG00000241962.51314.965601851.22800-0.493504.299903.48550HepG2MAGOH
C2ORF15ENSG00000273045.1115.18740183.66770-0.673102.571801.93780HepG2MAGOH
C2ORF15ENSG00000273045.197.10510184.69160-0.927503.885603.14920HepG2MATR3
C2orf15ENSG00000241962.5662.72040985.11380-0.571906.033304.88060HepG2MSI2
C2orf15ENSG00000241962.5853.068601905.46450-1.1594019.1833017.61090HepG2NCBP2
C2ORF15ENSG00000273045.1300.60620189.038800.669103.341602.64730HepG2NCBP2
C2orf15ENSG00000241962.5887.887101594.23220-0.8444018.2788016.42900HepG2NOL12
C2ORF15ENSG00000273045.1182.91020103.247900.824903.455002.61790HepG2NSUN2
C2orf15ENSG00000241962.5342.71300736.19640-1.103103.335602.35590HepG2PABPC1
C2orf15ENSG00000241962.51099.788401696.99010-0.625806.396105.31000HepG2PABPC4
C2orf15ENSG00000241962.51078.162501278.11640-0.245402.302001.52330HepG2PARN
C2ORF15ENSG00000273045.1142.9265091.626600.641302.428301.63050HepG2PARN
C2orf15ENSG00000241962.51400.381301682.73140-0.265003.097102.46050HepG2PCBP1
C2orf15ENSG00000241962.5823.158301151.71830-0.484504.268703.37390HepG2PPIL4
C2ORF15ENSG00000273045.1164.40580110.241800.576502.307201.59390HepG2PRPF4
C2orf15ENSG00000241962.5697.816401038.30400-0.573304.568603.55900HepG2PRPF8
C2ORF15ENSG00000273045.1108.4530059.748100.860002.342901.59630HepG2PRPF8
C2orf15ENSG00000241962.51051.605601712.22270-0.7033016.7779015.65020HepG2PTBP1
C2orf15ENSG00000241962.5904.556101521.79240-0.7505011.7855010.67280HepG2PUF60
C2orf15ENSG00000241962.51200.808201614.25130-0.426905.262604.35150HepG2PUM2
C2orf15ENSG00000241962.5800.737801084.58940-0.437706.172005.31730HepG2PUS1
C2orf15ENSG00000241962.51211.846001854.42090-0.613807.969206.99320HepG2QKI
C2ORF15ENSG00000273045.188.71560187.71020-1.081203.730103.02150HepG2QKI
C2ORF15ENSG00000273045.146.05330122.17920-1.407604.548403.65690HepG2RAVER1
C2orf15ENSG00000241962.5676.742901104.01510-0.706109.822008.34550HepG2RBM15
C2orf15ENSG00000241962.51398.528201682.99050-0.267102.166101.56420HepG2RBM25
C2orf15ENSG00000241962.51343.022401905.55570-0.504709.452408.56060HepG2NELFE
C2orf15ENSG00000241962.51095.408601774.73680-0.6961016.4526015.15510HepG2RECQL
C2orf15ENSG00000241962.5965.931801390.46230-0.525605.380904.47130HepG2RPLP0
C2orf15ENSG00000241962.5687.660001027.11160-0.578803.238602.39740HepG2RRP9
C2orf15ENSG00000241962.5791.530301149.93010-0.538807.753906.75560HepG2SAFB2
C2orf15ENSG00000241962.51540.392901191.397700.370502.112401.52200HepG2SF3A3
C2orf15ENSG00000241962.51382.226601782.67970-0.367105.291004.51850HepG2SF3B4
C2orf15ENSG00000241962.51082.692801340.98520-0.308704.329803.55670HepG2SMN1
C2orf15ENSG00000241962.51432.139402075.25580-0.535107.406306.69500HepG2SRFBP1
C2ORF15ENSG00000273045.1267.20620167.880300.670404.149203.57210HepG2SRFBP1
C2orf15ENSG00000241962.5598.54350818.14930-0.450902.414501.48650HepG2SRSF3
C2orf15ENSG00000241962.5881.267901268.23670-0.525202.693202.00630HepG2SRSF7
C2orf15ENSG00000241962.5894.093901513.78050-0.7597018.1998017.01200HepG2SRSF9
C2orf15ENSG00000241962.51535.156901801.69820-0.231001.861201.41930HepG2SSB
C2orf15ENSG00000241962.5892.580901339.74530-0.585904.598403.75920HepG2SUPV3L1
C2orf15ENSG00000241962.51437.012601672.44590-0.218902.012001.52080HepG2TAF15
C2ORF15ENSG00000273045.1175.83460113.461600.631902.423201.73810HepG2TARDBP
C2orf15ENSG00000241962.51055.059101536.79190-0.542607.426006.06930HepG2TIA1
C2orf15ENSG00000241962.5650.601801254.62050-0.9474018.9782017.88500HepG2TIAL1
C2orf15ENSG00000241962.5633.579901265.94780-0.9986027.2856025.74680HepG2TRIM56
C2orf15ENSG00000241962.5818.259601041.24090-0.347702.193601.62760HepG2U2AF1
C2ORF15ENSG00000273045.18.5149045.54950-2.419405.745004.64160HepG2UCHL5
C2orf15ENSG00000241962.5836.276601056.58880-0.337403.749102.95540HepG2UPF1
C2orf15ENSG00000241962.5802.352001226.90580-0.612703.942502.73420HepG2UPF2
C2orf15ENSG00000241962.51235.182501020.093200.275902.873202.26640HepG2UTP3
C2orf15ENSG00000241962.5923.032301162.04380-0.332204.415403.76650HepG2ZNF622
C2orf15ENSG00000241962.52822.295602472.228700.191002.050001.54770K562AGGF1
C2orf15ENSG00000241962.52608.915703281.80200-0.331002.881202.28320K562AQR
C2orf15ENSG00000241962.51866.265802234.47620-0.259802.937201.58180K562BCCIP
C2orf15ENSG00000241962.51713.395802159.32030-0.333705.213103.87820K562BCLAF1
C2orf15ENSG00000241962.51068.743101492.79920-0.482104.163003.08620K562BOP1
C2orf15ENSG00000241962.5800.022501106.63810-0.468103.996402.68170K562CCAR1
C2orf15ENSG00000241962.51252.402601587.27860-0.341903.138102.30200K562CPSF6
C2orf15ENSG00000241962.51332.143101638.16630-0.298303.136502.00230K562CSTF2
C2orf15ENSG00000241962.51416.438001836.12800-0.374403.880202.61740K562DDX3X
C2orf15ENSG00000241962.53753.157102768.343100.439008.091806.45690K562DKC1
C2orf15ENSG00000241962.51290.299401835.79740-0.508705.421504.11810K562EFTUD2
C2orf15ENSG00000241962.51771.597802553.50270-0.5274010.627709.35820K562EIF2S2
C2orf15ENSG00000241962.51395.278201965.46250-0.494303.929902.66980K562EIF3D
C2orf15ENSG00000241962.51592.439601918.27050-0.268602.052201.34220K562EIF4A3
C2orf15ENSG00000241962.53324.107204078.42300-0.295004.075702.93920K562EIF4G2
C2orf15ENSG00000241962.51377.634601771.13180-0.362502.426601.38310K562FKBP4
C2orf15ENSG00000241962.51066.825601615.00920-0.598206.688605.33740K562FMR1
C2orf15ENSG00000241962.5752.560901368.86200-0.8631010.839508.90400K562FTO
C2orf15ENSG00000241962.51684.544902028.44360-0.268002.841901.68640K562GLRX3
C2orf15ENSG00000241962.51109.892201515.46410-0.449304.496303.48830K562GPKOW
C2orf15ENSG00000241962.52837.250003402.71540-0.262202.393001.68780K562GRSF1
C2orf15ENSG00000241962.5643.200202040.22740-1.6654053.5860051.12060K562HNRNPC
C2orf15ENSG00000241962.51249.485801821.88120-0.544106.967905.07640K562HNRNPF
C2orf15ENSG00000241962.51869.133102481.35310-0.408804.734203.30800K562HNRNPL
C2orf15ENSG00000241962.51467.989002415.33670-0.718407.892405.82360K562IGF2BP2
C2orf15ENSG00000241962.51999.384702457.04760-0.297402.504001.38390K562IGF2BP3
C2orf15ENSG00000241962.5926.354001294.00760-0.482203.135602.13400K562KRR1
C2orf15ENSG00000241962.52055.379502534.19320-0.302102.866301.92610K562MATR3
C2orf15ENSG00000241962.51124.564501479.26050-0.395503.739802.71100K562METAP2
C2orf15ENSG00000241962.51881.547202369.62560-0.332707.225906.10170K562NSUN2
C2orf15ENSG00000241962.51807.734102259.42550-0.321802.531801.59760K562PCBP2
C2orf15ENSG00000241962.51595.123802265.47570-0.506104.802203.70850K562PCBP3
C2orf15ENSG00000241962.51295.647501737.69260-0.423504.745903.69720K562POLR2G
C2orf15ENSG00000241962.51438.001001829.26530-0.347202.715601.82120K562PSIP1
C2orf15ENSG00000241962.51646.325702466.95440-0.583506.966705.94950K562PTBP1
C2orf15ENSG00000241962.52976.138304449.92280-0.580308.727407.26730K562PUF60
C2orf15ENSG00000241962.53818.209004637.60620-0.280503.669202.56300K562PUM2
C2orf15ENSG00000241962.51763.361202551.40050-0.533005.761805.01270K562PUS1
C2orf15ENSG00000241962.51711.943202365.95120-0.466805.169103.98020K562RBM22
C2orf15ENSG00000241962.51376.408801668.90790-0.278002.202701.32110K562RCC2
C2orf15ENSG00000241962.51825.720802489.68310-0.447504.376502.96730K562NELFE
C2orf15ENSG00000241962.5948.218001441.24650-0.604005.390704.00090K562SF3B1
C2orf15ENSG00000241962.51635.364102418.34810-0.564408.757507.50680K562SRSF1
C2orf15ENSG00000241962.5917.709401534.44180-0.741603.179601.42170K562STIP1
C2orf15ENSG00000241962.51239.409501729.50900-0.480704.001102.76330K562SUPV3L1
C2orf15ENSG00000241962.51728.045802447.71930-0.502305.416604.41010K562TARDBP
C2orf15ENSG00000241962.51895.130102361.05090-0.317103.249602.35180K562TIA1
C2orf15ENSG00000241962.51133.308101759.45450-0.634606.855805.32650K562TIAL1
C2orf15ENSG00000241962.51441.869301869.12630-0.374403.519602.42760K562TRIM56
C2orf15ENSG00000241962.51611.107502110.91210-0.389804.647803.61240K562U2AF2
C2orf15ENSG00000241962.51418.430201830.55040-0.368002.924201.87210K562UCHL5
C2orf15ENSG00000241962.52118.685502512.55760-0.246003.418202.62500K562UPF1
C2orf15ENSG00000241962.51757.771502149.92700-0.290502.671001.80870K562WDR3
C2orf15ENSG00000241962.51815.021902235.60080-0.300704.900103.80240K562WDR43
C2orf15ENSG00000241962.51455.478301864.13530-0.357002.786601.57560K562XRN2
C2orf15ENSG00000241962.52807.855503696.73700-0.396804.359303.23610K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C2ORF15 is not available on ENCORE database.





1 RBPs can affect the splicing of C2ORF15 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC2orf15ENSG00000241962.5chr2+9976348999763585997587479975886499763864997639560.130000.000020.00865includedHepG2HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C2ORF15 is not avaliable on ENCORE database.