THAP6

General Information

Gene Name       : THAP6
Gene ID             : ENSG00000174796.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: THAP6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878THAP6ENSG00000174796.1212.999.7011.34ENCSR000AEF
HepG2THAP6ENSG00000174796.125.099.577.33ENCSR985KAT
K562THAP6ENSG00000174796.1213.0713.3213.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for THAP6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • THAP6 RNA is bound by 3 proteins.  







eCLIP assay for THAP6 is not avaliable on ENCORE database.





3 proteins are bound to THAP6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr47644775276447845+3'-UTR,intron-Distal5.148594.38664K562QKI
chr47646512176465170+3'-UTR,CDS,intron-Distal,intron-Proximal4.215073.45943HepG2BCLAF1
chr47646819176468276+3'-UTR,intron-Distal3.905523.45317HepG2HNRNPL
chr47644206276442195+CDS,intron-Proximal3.593116.39464HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for THAP6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for THAP6 is not available on ENCORE database.

  • 49 RBPs can affect the levels of THAP6.  








The Knockdown/knockout RNA-Seq assay for THAP6 is not available on ENCORE database.





49 RBPs can affect the gene expression of THAP6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
THAP6ENSG00000174796.8476.40300343.415100.472102.239401.75620HepG2AKAP1
THAP6ENSG00000174796.8390.09980262.106200.573603.408102.75080HepG2BOP1
THAP6ENSG00000174796.8440.39900295.320500.576402.058601.40440HepG2CNOT7
THAP6ENSG00000174796.8248.88450175.195200.506402.247101.43450HepG2DDX24
THAP6ENSG00000174796.8442.87520329.000800.428702.120601.56590HepG2DDX3X
THAP6ENSG00000174796.8134.70980282.53580-1.068605.371004.53660HepG2DDX6
THAP6ENSG00000174796.8279.02270201.003800.473102.214401.33760HepG2DHX30
THAP6ENSG00000174796.8260.98500164.858600.662603.007001.84420HepG2AGO1
THAP6ENSG00000174796.8547.00920446.542600.292701.844501.33280HepG2ETF1
THAP6ENSG00000174796.8400.98090272.732800.555902.807302.16220HepG2GPKOW
THAP6ENSG00000174796.8433.51950295.343400.553604.058702.96100HepG2HNRNPA2B1
THAP6ENSG00000174796.8407.19570260.276400.645603.893003.15820HepG2HNRNPLL
THAP6ENSG00000174796.8433.77820311.872900.475902.387701.79670HepG2NCBP2
THAP6ENSG00000174796.8284.33110210.351200.434702.237001.53430HepG2PRPF4
THAP6ENSG00000174796.8259.26730171.597500.595303.021102.17990HepG2PRPF8
THAP6ENSG00000174796.8424.94030326.019100.382202.160301.59630HepG2QKI
THAP6ENSG00000174796.8418.08190275.156900.603403.515002.76020HepG2RPLP0
THAP6ENSG00000174796.8546.79280286.638300.931705.861604.71630HepG2SNRNP70
THAP6ENSG00000174796.8521.05460421.557700.305602.086901.63230HepG2SRFBP1
THAP6ENSG00000174796.8345.06890266.149300.374502.186301.68380HepG2SRSF9
THAP6ENSG00000174796.8348.46970221.325200.654803.781403.00900HepG2SUPV3L1
THAP6ENSG00000174796.8374.65140294.061100.349301.776301.30770HepG2TAF15
THAP6ENSG00000174796.8298.55450225.962700.401801.891701.46110HepG2TIAL1
THAP6ENSG00000174796.8402.06910251.509600.676703.887003.14690HepG2U2AF1
THAP6ENSG00000174796.8502.02830723.61450-0.527505.359404.61140K562AGGF1
THAP6ENSG00000174796.8486.58540752.94820-0.629905.991705.00660K562AKAP8L
THAP6ENSG00000174796.8487.58810633.91120-0.378601.986901.47480K562AQR
THAP6ENSG00000174796.8292.01850393.43590-0.430102.676101.39280K562BCCIP
THAP6ENSG00000174796.8648.38280810.26050-0.321502.703401.84010K562DKC1
THAP6ENSG00000174796.8244.91270338.56750-0.467202.435001.66390K562EIF4A3
THAP6ENSG00000174796.8641.82840789.92990-0.299502.396101.51770K562EIF4G2
THAP6ENSG00000174796.8565.91200392.619000.527302.907602.17980K562G3BP2
THAP6ENSG00000174796.8341.97580477.34390-0.481102.425401.48320K562IGF2BP2
THAP6ENSG00000174796.8349.41880501.69650-0.521904.006402.98880K562MAGOH
THAP6ENSG00000174796.8694.39940895.17480-0.366402.756501.85000K562MBNL1
THAP6ENSG00000174796.8239.32990576.19300-1.267607.400305.51950K562PABPN1
THAP6ENSG00000174796.8333.01560446.39060-0.422702.314701.42420K562PCBP2
THAP6ENSG00000174796.8376.43730268.144600.489302.795601.98970K562POLR2G
THAP6ENSG00000174796.8325.04140483.92200-0.574204.054503.03730K562PPIG
THAP6ENSG00000174796.8297.61860487.42760-0.711706.780305.77700K562PTBP1
THAP6ENSG00000174796.8668.90840861.85910-0.365602.325801.57720K562PUF60
THAP6ENSG00000174796.8440.00560746.75720-0.763107.885807.01650K562PUS1
THAP6ENSG00000174796.8422.79540727.56990-0.7831010.076808.97020K562RBM15
THAP6ENSG00000174796.8324.37110467.39960-0.527003.608602.63780K562RBM22
THAP6ENSG00000174796.8320.85210527.00510-0.715902.479901.36870K562SF1
THAP6ENSG00000174796.8291.21450408.41090-0.487903.282402.34970K562SF3B4
THAP6ENSG00000174796.8373.39220477.83850-0.355801.959701.35180K562SRSF1
THAP6ENSG00000174796.8305.93860483.61030-0.660605.002204.03570K562TARDBP
THAP6ENSG00000174796.8205.17970295.29260-0.525302.460301.34150K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for THAP6 is not available on ENCORE database.





3 RBPs can affect the splicing of THAP6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETHAP6ENSG00000174796.8chr4+764406427644074276439698764397307644198176442189-0.091000.000100.03573excludedK562PUM1
SETHAP6ENSG00000174796.8chr4+764406427644074276439698764397307644198176442189-0.147000.001860.03740excludedK562U2AF1
SETHAP6ENSG00000174796.8chr4+7644694576447071764419817644218976465068764651690.158000.000070.02705includedK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for THAP6 is not avaliable on ENCORE database.