RNF214

General Information

Gene Name       : RNF214
Gene ID             : ENSG00000167257.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RNF214)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RNF214ENSG00000167257.1012.579.4110.99ENCSR000AEF
HepG2RNF214ENSG00000167257.1011.1113.1812.14ENCSR985KAT
K562RNF214ENSG00000167257.1014.6215.2914.95ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
RNF214Ribo-STAMP-293TshRNABGRSLV05-9,BGRSLV05-10BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
RNF214Ribo-STAMP-293TshRNARNF214-BGRSLV07-19,RNF214-BGRSLV07-20NT-BGRSLV07-1,NT-BGRSLV07-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RNF214 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RNF214 RNA is bound by 18 proteins.  







eCLIP assay for RNF214 is not avaliable on ENCORE database.





18 proteins are bound to RNF214 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11117155941117156027+3'-UTR3.8515110.31435K562PUM2
chr11117156043117156104+3'-UTR5.0460311.15990K562PUM2
chr11117155848117155896+3'-UTR,CDS3.568364.49887K562ZNF622
chr11117104954117105015+5'-UTR,CDS,intron-Proximal4.096406.32052K562AQR
chr11117152711117152831+CDS,intron-Distal,intron-Proximal4.546799.97474K562PCBP1
chr11117117598117117665+CDS,intron-Proximal4.165255.35382K562ZNF800
chr11117115191117115280+CDS4.187845.06180HepG2BCLAF1
chr11117152028117152063+CDS,intron-Proximal4.791074.37348HepG2BCLAF1
chr11117152804117152883+CDS,intron-Distal,intron-Proximal3.934553.57018HepG2HNRNPK
chr11117150616117150714+CDS,intron-Proximal3.832275.56912HepG2AQR
chr11117150683117150721+CDS,intron-Proximal4.300858.92108K562UCHL5
chr11117117616117117668+CDS,intron-Proximal3.445385.15776HepG2BCLAF1
chr11117105092117105263+CDS,intron-Distal,intron-Proximal4.030825.25185K562PRPF8
chr11117150692117150721+CDS,intron-Proximal4.527135.10960K562ZNF622
chr11117152051117152106+CDS5.6652712.72740K562LIN28B
chr11117117526117117598+CDS3.250214.93055K562ZNF800
chr11117150623117150692+CDS,intron-Proximal3.998275.80935K562ZNF622
chr11117117600117117663+CDS3.284416.21720K562BUD13
chr11117152796117152906+CDS,intron-Distal,intron-Proximal3.628605.26527K562IGF2BP2
chr11117117593117117662+CDS5.5224010.53537K562ZNF622
chr11117117569117117654+CDS4.039733.53509HepG2HLTF
chr11117150886117150921+CDS,intron-Proximal3.671884.24220K562ZNF622
chr11117150886117150945+CDS,intron-Proximal3.407784.89070K562UCHL5
chr11117117535117117680+CDS,intron-Proximal5.7405925.48444K562UCHL5
chr11117152715117152922+CDS,intron-Distal,intron-Proximal3.733584.79909K562HNRNPK
chr11117115235117115299+CDS5.188319.06345K562UCHL5
chr11117109290117109342+CDS,intron-Proximal5.442347.81430K562AQR
chr11117110559117110628+CDS,intron-Proximal4.432064.75425K562EFTUD2
chr11117150624117150683+CDS5.6208212.00022K562UCHL5
chr11117150948117150976+CDS,intron-Proximal4.715074.37348HepG2BCLAF1
chr11117109940117109988+intron-Distal3.796644.93376K562PRPF8
chr11117126838117126965+intron-Distal4.767236.58335HepG2QKI
chr11117103554117103606+intron-Distal,intron-Proximal4.784594.65563K562AQR
chr11117110628117110688+intron-Distal,intron-Proximal5.271094.24111K562EFTUD2
chr11117103494117103544+intron-Distal,intron-Proximal3.784593.52230K562AQR
chr11117125979117126076+intron-Distal3.856084.69074K562PTBP1
chr11117103644117103732+intron-Distal3.866353.19526HepG2CSTF2T
chr11117125844117125946+intron-Distal4.102243.62238HepG2MATR3
chr11117105097117105187+intron-Proximal4.374887.50107K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RNF214 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RNF214 is not available on ENCORE database.

  • 23 RBPs can affect the levels of RNF214.  








The Knockdown/knockout RNA-Seq assay for RNF214 is not available on ENCORE database.





23 RBPs can affect the gene expression of RNF214 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RNF214ENSG00000167257.6565.18700746.15020-0.400703.869503.08280HepG2AUH
RNF214ENSG00000167257.6306.52110484.09130-0.659303.914003.18900HepG2DDX6
RNF214ENSG00000167257.6311.49190401.03110-0.364502.105601.48360HepG2DNAJC21
RNF214ENSG00000167257.6378.05690514.46680-0.444502.217101.64280HepG2EIF4A3
RNF214ENSG00000167257.6322.24050453.74060-0.493703.307102.39470HepG2EWSR1
RNF214ENSG00000167257.6483.39930348.616500.471502.849502.05180HepG2FUBP3
RNF214ENSG00000167257.6338.41780450.33730-0.412202.147701.52750HepG2HNRNPC
RNF214ENSG00000167257.6457.50740638.98880-0.482002.338601.59150HepG2MSI2
RNF214ENSG00000167257.6405.83800543.02170-0.420102.731702.13860HepG2PUF60
RNF214ENSG00000167257.6705.72540557.783700.339302.811302.33500HepG2SRSF1
RNF214ENSG00000167257.6890.44080541.583400.717203.198802.05400HepG2TBRG4
RNF214ENSG00000167257.6403.38800583.59230-0.532805.141404.36780HepG2UTP3
RNF214ENSG00000167257.6534.21860664.80150-0.315502.791202.24270HepG2ZNF622
RNF214ENSG00000167257.6992.730001241.30780-0.322403.471602.84910K562AGGF1
RNF214ENSG00000167257.6946.130301291.63300-0.449104.184203.37820K562AKAP8L
RNF214ENSG00000167257.6755.53180960.82760-0.346802.155501.62630K562AQR
RNF214ENSG00000167257.61567.569101166.338100.426406.462505.52460K562DDX47
RNF214ENSG00000167257.6634.19680774.71440-0.288702.161401.51250K562EIF2S2
RNF214ENSG00000167257.6733.746001032.41160-0.492704.626003.64990K562GRSF1
RNF214ENSG00000167257.6997.23040780.092800.354203.271302.30220K562HNRNPU
RNF214ENSG00000167257.6732.62300930.37540-0.344703.358102.47060K562MTPAP
RNF214ENSG00000167257.61136.203601400.70260-0.301902.236701.50410K562PUF60
RNF214ENSG00000167257.61116.024601459.77310-0.387404.625503.37370K562PUM2
RNF214ENSG00000167257.6994.263401248.09270-0.328003.083202.46260K562RBM15
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RNF214 is not available on ENCORE database.





5 RBPs can affect the splicing of RNF214 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERNF214ENSG00000167257.6chr11+117109621117109827117109316117109362117110516117110576-0.242000.002370.04176excludedK562SRSF1
SERNF214ENSG00000167257.6chr11+117153461117153566117153119117153252117153830117153926-0.322000.000690.01496excludedHepG2U2AF1
A3SSRNF214ENSG00000167257.6chr11+1171530821171532521171531191171532521171528801171529860.073000.007610.04176longerK562AQR
A3SSRNF214ENSG00000167257.6chr11+1171505961171507201171506231171507201171175241171176640.114000.000000.00000longerK562AQR
A5SSRNF214ENSG00000167257.6chr11+117109316117109827117109316117109362117110516117110576-0.206000.001230.06382shorterK562SRSF1
RIRNF214ENSG00000167257.6chr11+117109316117110576117109316117109827117110516117110576-0.057000.000170.01556excludedK562DROSHA
RIRNF214ENSG00000167257.6chr11+1171093161171105761171093161171098271171105161171105760.058000.000670.00909includedHepG2RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RNF214 is not avaliable on ENCORE database.