POLR1A

General Information

Gene Name : POLR1A
Gene ID : ENSG00000068654.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLR1A)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLR1A	ENSG00000068654.15	18.81	16.44	17.62	ENCSR000AEF
HepG2	POLR1A	ENSG00000068654.15	25.28	26.26	25.77	ENCSR985KAT
K562	POLR1A	ENSG00000068654.15	20.69	23.32	22.01	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLR1A is not avaliable on ENCORE database.

Proteins bound to RNA

POLR1A RNA is bound by 32 proteins.

CanvasJS.com

eCLIP assay for POLR1A is not avaliable on ENCORE database.

32 proteins are bound to POLR1A RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	86253814	86253986	-	3'-UTR,intron-Distal	5.77398	26.58750	HepG2	UPF1
chr2	86259546	86259729	-	intron-Distal,intron-Proximal	6.11957	19.24847	HepG2	RBFOX2
chr2	86258403	86258439	-	intron-Distal,intron-Proximal	6.45075	18.99425	K562	AQR
chr2	86269967	86270100	-	CDS,intron-Distal,intron-Proximal	6.38060	18.07825	K562	AQR
chr2	86253631	86253774	-	3'-UTR,intron-Distal	4.69615	17.89224	HepG2	UPF1
chr2	86258399	86258446	-	intron-Distal,intron-Proximal	4.99502	17.45859	HepG2	PRPF8
chr2	86253078	86253193	-	3'-UTR,intron-Distal	5.22805	16.89434	K562	UPF1
chr2	86254234	86254322	-	3'-UTR,intron-Distal	5.84240	15.66923	HepG2	UPF1
chr2	86258439	86258454	-	CDS,intron-Distal,intron-Proximal	6.14643	14.81397	K562	AQR
chr2	86253288	86253386	-	3'-UTR,intron-Distal,intron-Proximal	4.41881	14.13313	HepG2	UPF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 155 entries

eCLIP assay for POLR1A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLR1A is not available on ENCORE database.
139 RBPs can affect the levels of POLR1A.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for POLR1A is not available on ENCORE database.

139 RBPs can affect the gene expression of POLR1A :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLR1A	ENSG00000068654.11	4007.03060	1569.80250	1.35190	67.52770	64.84730	K562	FXR1
POLR1A	ENSG00000068654.11	4059.44560	1895.29340	1.09880	59.34900	57.80000	HepG2	SRSF1
POLR1A	ENSG00000068654.11	3951.92070	2451.89560	0.68860	31.98030	30.41520	HepG2	PUM1
POLR1A	ENSG00000068654.11	4089.17560	2393.47280	0.77260	31.22560	29.54640	HepG2	UTP3
POLR1A	ENSG00000068654.11	2239.52420	1139.84360	0.97430	21.73900	20.27350	HepG2	RPS19
POLR1A	ENSG00000068654.11	2576.22060	4765.25300	-0.88730	17.98020	16.07650	K562	HSPD1
POLR1A	ENSG00000068654.11	2964.07710	1708.86670	0.79440	17.24940	15.65770	K562	PTBP1
POLR1A	ENSG00000068654.11	2691.28240	1744.17310	0.62570	16.38680	15.26960	HepG2	PTBP1
POLR1A	ENSG00000068654.11	1107.67840	2265.64300	-1.03240	15.89970	14.51180	HepG2	SUPV3L1
POLR1A	ENSG00000068654.11	3815.42150	1903.89010	1.00280	15.67440	14.26390	HepG2	MATR3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 167 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLR1A is not available on ENCORE database.

3 RBPs can affect the splicing of POLR1A :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	POLR1A	ENSG00000068654.11	chr2	-	86271261	86271427	86270096	86270318	86272739	86272892	-0.27200	0.00000	0.00005	excluded	HepG2	U2AF1
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86305236	86305459	86305236	86305407	86307938	86308101	0.07500	0.00001	0.00010	longer	K562	AQR
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86276282	86276477	86276282	86276365	86279939	86280165	0.13400	0.00003	0.00026	longer	K562	AQR
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86279939	86280165	86279939	86280123	86281262	86281412	0.12500	0.00004	0.00037	longer	K562	AQR
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86281262	86281434	86281262	86281412	86292396	86292588	0.07500	0.00012	0.00101	longer	K562	AQR
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86315907	86316020	86315907	86315993	86316944	86317052	0.13400	0.00076	0.00547	longer	K562	AQR
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86276282	86276477	86276282	86276365	86279939	86280123	0.05400	0.00125	0.04820	longer	HepG2	U2AF1
SE	POLR1A	ENSG00000068654.11	chr2	-	86261050	86261195	86260783	86260910	86265822	86265980	-0.05200	0.00142	0.05180	excluded	K562	FXR1
A3SS	POLR1A	ENSG00000068654.11	chr2	-	86308723	86308874	86308723	86308829	86310204	86310291	0.08300	0.00550	0.03143	longer	K562	AQR
SE	POLR1A	ENSG00000068654.11	chr2	-	86271261	86271427	86270096	86270318	86272400	86272483	-0.05800	0.01111	0.08828	excluded	K562	AQR

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLR1A

General Information

Functions

Localization

Domains (AlphaFold: POLR1A)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLR1A is not avaliable on ENCORE database.

32 proteins are bound to POLR1A RNA:

eCLIP assay for POLR1A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLR1A is not available on ENCORE database.

139 RBPs can affect the gene expression of POLR1A :

The Knockdown/knockout RNA-Seq assay for POLR1A is not available on ENCORE database.

3 RBPs can affect the splicing of POLR1A :

The Knockdown/knockout RNA-Seq assay for POLR1A is not avaliable on ENCORE database.