LYAR

General Information

Gene Name       : LYAR
Gene ID             : ENSG00000145220.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LYAR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LYARENSG00000145220.1351.6655.7853.72ENCSR000AEF
HepG2LYARENSG00000145220.1348.0274.6261.32ENCSR985KAT
K562LYARENSG00000145220.1392.35111.96102.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
LYARRibo-STAMP-293TshRNALYAR-BGRSLV04-17,LYAR-BGRSLV04-18NT-BGRSLV04-1,NT-BGRSLV04-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LYAR is not avaliable on ENCORE database.



Proteins bound to RNA
  • LYAR RNA is bound by 14 proteins.  







eCLIP assay for LYAR is not avaliable on ENCORE database.





14 proteins are bound to LYAR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr442854864285524-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.159624.77486K562YBX3
chr442881864288252-5'-UTR,intron-Distal,intron-Proximal3.646214.23459K562PRPF8
chr442882234288271-5'-UTR,intron-Distal,intron-Proximal5.426424.02817HepG2PRPF8
chr442917104291771-5'-UTR,intron-Distal,intron-Proximal3.955284.45914HepG2PRPF8
chr442882454288300-5'-UTR,intron-Distal,intron-Proximal3.216636.75993K562DDX3X
chr442917604291871-5'-UTR,intron-Distal,intron-Proximal4.2608323.51144K562DDX3X
chr442834744283532-CDS,intron-Distal,intron-Proximal4.141267.29769HepG2PRPF8
chr442761974276279-CDS,intron-Distal3.829203.91655K562CPSF6
chr442696544269672-CDS,intron-Distal4.483404.77252K562ZNF622
chr442854094285434-CDS,intron-Distal3.173674.35477K562UCHL5
chr442761754276258-CDS,intron-Distal5.0363922.48136K562UCHL5
chr442753114275382-CDS,intron-Distal3.407153.93631K562AQR
chr442761564276271-CDS,intron-Distal4.613304.83264K562TRA2A
chr442753114275373-CDS,intron-Distal4.064397.71102K562ZNF622
chr442813434281399-CDS,intron-Distal,intron-Proximal4.757134.35676HepG2PRPF8
chr442835824283624-CDS,intron-Distal3.115134.88466K562UCHL5
chr442760924276144-CDS,intron-Distal,intron-Proximal3.758493.35522K562SRSF7
chr442752584275311-CDS,intron-Distal,intron-Proximal4.416117.92018K562AQR
chr442762604276429-CDS,intron-Distal3.035505.97539K562GRWD1
chr442753304275364-CDS,intron-Distal4.079386.43326K562UCHL5
chr442763504276452-CDS,intron-Distal3.398883.81194K562TRA2A
chr442760924276197-CDS,intron-Distal,intron-Proximal3.620959.34909K562CPSF6
chr442813704281414-CDS,intron-Distal3.196136.35635K562UCHL5
chr442813924281400-CDS,intron-Distal3.860844.82082K562ZNF622
chr442762734276352-CDS,intron-Distal4.675739.53697K562ZNF622
chr442762874276402-CDS,intron-Distal3.460715.07370K562CPSF6
chr442753854275396-CDS,intron-Distal3.895835.08388K562UCHL5
chr442763974276409-CDS,intron-Distal3.874306.12731K562UCHL5
chr442833974283535-CDS,intron-Distal,intron-Proximal5.0549512.63563K562PRPF8
chr442761804276258-CDS,intron-Distal3.824604.22460K562RBM15
chr442760944276160-CDS,intron-Distal3.8868714.68801K562UCHL5
chr442854074285452-CDS,intron-Distal3.387076.21602K562ZNF622
chr442814224281453-CDS,intron-Distal3.247394.39540K562PUM1
chr442764564276494-CDS,intron-Distal3.284413.13705K562BUD13
chr442760954276173-CDS,intron-Distal3.4716111.15182K562ZNF622
chr442835274283625-CDS,intron-Distal,intron-Proximal4.415548.80935HepG2BCLAF1
chr442852744285355-CDS,intron-Distal,intron-Proximal4.5549510.39215K562PRPF8
chr442762584276333-CDS,intron-Distal4.6534314.84359K562UCHL5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LYAR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LYAR is not available on ENCORE database.

  • 115 RBPs can affect the levels of LYAR.  








The Knockdown/knockout RNA-Seq assay for LYAR is not available on ENCORE database.





115 RBPs can affect the gene expression of LYAR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LYARENSG00000145220.9436.39850588.47950-0.431303.777102.89370HepG2AKAP8L
LYARENSG00000145220.9563.48380977.70720-0.7950014.8071013.44250HepG2AUH
LYARENSG00000145220.9278.60480595.77870-1.0966010.362208.76540HepG2BCLAF1
LYARENSG00000145220.9721.595301626.36310-1.1724023.7286022.25000HepG2BOP1
LYARENSG00000145220.9487.01140744.56830-0.612402.518501.34390HepG2BUD13
LYARENSG00000145220.9625.78530878.20790-0.488904.896203.90700HepG2CALR
LYARENSG00000145220.9690.944701306.21650-0.918804.203902.98800HepG2CCAR1
LYARENSG00000145220.9426.39110585.60760-0.457804.584503.76990HepG2CKAP4
LYARENSG00000145220.9489.473401493.08730-1.6090036.3797034.29120HepG2CPSF6
LYARENSG00000145220.9664.68810865.40480-0.380704.643203.72060HepG2DAZAP1
LYARENSG00000145220.9221.60830487.50560-1.137408.802307.66260HepG2DDX21
LYARENSG00000145220.9354.05500476.74990-0.429302.763001.85100HepG2DDX24
LYARENSG00000145220.9298.28720490.35150-0.717105.022504.20100HepG2DDX3X
LYARENSG00000145220.9463.53330674.05090-0.540202.863602.07830HepG2DDX55
LYARENSG00000145220.91128.457601695.51120-0.587403.172702.12640HepG2DDX59
LYARENSG00000145220.9607.12830786.88490-0.374202.270801.35450HepG2DDX5
LYARENSG00000145220.9243.11580421.19280-0.792805.018104.20780HepG2DDX6
LYARENSG00000145220.9284.35130466.53610-0.714304.486103.25030HepG2DHX30
LYARENSG00000145220.9298.89430560.36010-0.906709.098908.01230HepG2DKC1
LYARENSG00000145220.9295.98110483.72030-0.708707.124806.03910HepG2DNAJC21
LYARENSG00000145220.9301.81310479.39870-0.667607.649806.63710HepG2DNAJC2
LYARENSG00000145220.9179.24150404.93190-1.1758010.181909.08670HepG2EIF2S1
LYARENSG00000145220.9604.10400435.688400.471402.214501.59600HepG2EIF4B
LYARENSG00000145220.9505.98640817.84240-0.692706.981905.71240HepG2EIF4G2
LYARENSG00000145220.9847.652401122.53010-0.405204.971204.20770HepG2ETF1
LYARENSG00000145220.9849.803001495.65200-0.815603.696002.51590HepG2FTO
LYARENSG00000145220.9210.22950359.70110-0.774805.419304.32960HepG2FUBP3
LYARENSG00000145220.9222.40150418.83420-0.913206.915405.88270HepG2G3BP1
LYARENSG00000145220.9276.02350459.43440-0.735105.123203.73290HepG2GNB2L1
LYARENSG00000145220.9661.322601692.52340-1.3557023.8998022.22170HepG2GPKOW
LYARENSG00000145220.9244.92060488.35390-0.995609.606608.51000HepG2HNRNPA1
LYARENSG00000145220.9647.01660795.31780-0.297702.461801.57300HepG2HNRNPA2B1
LYARENSG00000145220.9310.80560543.18680-0.805407.080706.01180HepG2HNRNPC
LYARENSG00000145220.9663.936901189.86890-0.841709.868708.62060HepG2HNRNPF
LYARENSG00000145220.9610.04920424.055300.524603.603402.81240HepG2HNRNPK
LYARENSG00000145220.9543.36600788.32620-0.536907.297406.24920HepG2HNRNPL
LYARENSG00000145220.9449.787001615.20690-1.8444045.2724043.23150HepG2HNRNPLL
LYARENSG00000145220.9347.89290539.59680-0.633206.945906.02210HepG2HNRNPU
LYARENSG00000145220.9575.320001171.69860-1.026208.383207.18640HepG2IGF2BP1
LYARENSG00000145220.9416.24930551.18310-0.405103.822602.97440HepG2ILF2
LYARENSG00000145220.9425.67630535.42280-0.330902.573701.58890HepG2KIF1C
LYARENSG00000145220.9865.74630454.169800.930609.314308.21290HepG2MATR3
LYARENSG00000145220.9462.17870812.25750-0.813504.110603.13320HepG2MSI2
LYARENSG00000145220.9699.474901647.31720-1.2358014.1779011.99570HepG2MTPAP
LYARENSG00000145220.9660.51440858.13200-0.377603.363102.52390HepG2NOL12
LYARENSG00000145220.9719.093201432.19520-0.9940016.0187014.38740HepG2NSUN2
LYARENSG00000145220.9528.28510429.572400.298301.895701.37710HepG2PCBP1
LYARENSG00000145220.9279.11960520.12700-0.898006.994005.77860HepG2PRPF8
LYARENSG00000145220.9645.18870819.15410-0.344402.422201.85870HepG2PUF60
LYARENSG00000145220.9637.05140868.92950-0.447804.207103.38940HepG2PUM2
LYARENSG00000145220.9352.19660596.57210-0.7603010.509709.44140HepG2PUS1
LYARENSG00000145220.9322.20550473.40840-0.555104.253603.50330HepG2QKI
LYARENSG00000145220.9974.29720554.147000.814004.917503.99220HepG2RAVER1
LYARENSG00000145220.9604.14100933.23440-0.627407.618306.29550HepG2RBM15
LYARENSG00000145220.9563.97020938.22920-0.7343011.0283010.14440HepG2RBM22
LYARENSG00000145220.9701.08150542.728100.369302.188301.31650HepG2RBM27
LYARENSG00000145220.9626.04150440.718800.506303.186302.04600HepG2RCC2
LYARENSG00000145220.9842.596601281.51950-0.604906.104305.14640HepG2RPLP0
LYARENSG00000145220.9365.56580514.52810-0.493102.303601.57930HepG2RRP9
LYARENSG00000145220.9421.64180266.149600.663703.736102.21790HepG2SART3
LYARENSG00000145220.91071.102001598.73150-0.577806.745505.68520HepG2SF3B1
LYARENSG00000145220.9568.88010785.42170-0.465305.649904.70700HepG2SLBP
LYARENSG00000145220.9679.87770560.412800.278702.267401.67530HepG2SMN1
LYARENSG00000145220.9823.465201778.87070-1.1112011.473509.89800HepG2SNRNP70
LYARENSG00000145220.9769.825001059.69860-0.461106.195005.52740HepG2SRFBP1
LYARENSG00000145220.9699.77060475.009500.558805.869405.24490HepG2SRSF1
LYARENSG00000145220.91298.397601720.25270-0.405902.592601.62710HepG2SRSF3
LYARENSG00000145220.9608.663601168.94670-0.9415011.228609.98920HepG2SRSF7
LYARENSG00000145220.9519.16160920.07480-0.8256015.5929014.57890HepG2SSB
LYARENSG00000145220.9362.51920245.850900.560202.805101.69620HepG2STIP1
LYARENSG00000145220.9436.54300677.69680-0.634502.679101.75120HepG2SUPT6H
LYARENSG00000145220.9256.97210671.05110-1.3848015.2623013.89840HepG2SUPV3L1
LYARENSG00000145220.9477.083201574.34610-1.7224043.7797041.57200HepG2TARDBP
LYARENSG00000145220.9332.71640524.38170-0.656305.994505.31140HepG2TIAL1
LYARENSG00000145220.9428.32250529.00210-0.304602.153501.64340HepG2TRIM56
LYARENSG00000145220.91096.73310858.311700.353502.437001.84410HepG2U2AF1
LYARENSG00000145220.9568.29520847.05620-0.575804.103503.07410HepG2UBE2L3
LYARENSG00000145220.9546.59160754.53590-0.465105.138404.23270HepG2UPF1
LYARENSG00000145220.91232.81680728.477400.7589015.6944014.44010HepG2UTP3
LYARENSG00000145220.9486.22220736.94090-0.599907.703706.67520HepG2ZC3H8
LYARENSG00000145220.9610.38370829.84750-0.443105.744505.03110HepG2ZNF622
LYARENSG00000145220.91161.730001587.26170-0.450304.801203.41840K562AKAP8
LYARENSG00000145220.91351.639701636.82130-0.276203.005501.62810K562BCCIP
LYARENSG00000145220.91223.449201581.88010-0.370705.587504.20840K562BCLAF1
LYARENSG00000145220.91499.466203389.16080-1.1765017.2086015.00650K562BOP1
LYARENSG00000145220.91378.429101726.50990-0.324803.471302.13080K562CCDC124
LYARENSG00000145220.91077.920001371.03530-0.347002.721401.45300K562CIRBP
LYARENSG00000145220.92451.819904748.13330-0.953507.365705.58650K562CNOT7
LYARENSG00000145220.91587.651003603.75080-1.1826020.8635018.69640K562CPSF6
LYARENSG00000145220.9627.75580966.78110-0.623007.420305.62070K562DDX3X
LYARENSG00000145220.94796.868103618.633700.406509.037007.94300K562DDX47
LYARENSG00000145220.92203.509001617.724400.445705.250803.99120K562DKC1
LYARENSG00000145220.9937.921901303.64400-0.475003.967502.85880K562EFTUD2
LYARENSG00000145220.9795.805101061.88180-0.416105.118603.44460K562EIF2S1
LYARENSG00000145220.91371.027502622.20150-0.9355029.9520028.04420K562EIF2S2
LYARENSG00000145220.91818.229301183.429400.6195011.8190010.15460K562EIF3G
LYARENSG00000145220.9788.260401010.03130-0.357702.727701.91270K562EIF4A3
LYARENSG00000145220.9953.857601266.06360-0.408503.396701.60840K562FASTKD2
LYARENSG00000145220.91656.108703666.53640-1.1466019.7809017.43120K562FMR1
LYARENSG00000145220.91749.184703107.63590-0.8291011.043709.09410K562FTO
LYARENSG00000145220.91990.854701050.387200.9224025.8977024.16060K562FXR1
LYARENSG00000145220.91925.575003440.77550-0.8374011.276209.64930K562GPKOW
LYARENSG00000145220.92783.998203494.50960-0.327903.396202.56090K562GRSF1
LYARENSG00000145220.9787.654601275.33960-0.695203.714001.44860K562HLTF
LYARENSG00000145220.9776.724101704.76490-1.134105.692804.86700K562HNRNPC
LYARENSG00000145220.91829.520901277.662400.517904.911403.21920K562HNRNPK
LYARENSG00000145220.9938.772201279.16320-0.446403.026101.93640K562IGF2BP2
LYARENSG00000145220.91698.609502937.78250-0.790406.778705.24910K562KRR1
LYARENSG00000145220.91974.741603358.54690-0.766209.006707.35650K562METAP2
LYARENSG00000145220.92594.621903797.88900-0.549706.764205.02620K562MSI2
LYARENSG00000145220.91887.281902470.33430-0.388402.561401.78160K562MTPAP
LYARENSG00000145220.91898.657402745.03480-0.531805.257704.27620K562NSUN2
LYARENSG00000145220.91488.785702277.19280-0.613106.744205.44330K562PCBP3
LYARENSG00000145220.91622.107502130.19610-0.393103.087401.43240K562PKM
LYARENSG00000145220.91227.955601746.62330-0.508306.792705.54790K562POLR2G
LYARENSG00000145220.91745.108601268.590000.460004.501303.54580K562PRPF8
LYARENSG00000145220.91591.231601306.184800.284702.155901.55800K562PTBP1
LYARENSG00000145220.93279.575704051.54220-0.305003.909202.76490K562PUM2
LYARENSG00000145220.9705.31800927.66300-0.395303.059201.65330K562RBM25
LYARENSG00000145220.92077.411401556.475800.416404.547403.15090K562SAFB
LYARENSG00000145220.92853.475504324.64570-0.599903.772201.92340K562SBDS
LYARENSG00000145220.91526.739102708.24490-0.8269010.418008.91040K562SF3A3
LYARENSG00000145220.92265.413603272.00690-0.530403.630802.50940K562SF3B1
LYARENSG00000145220.91272.120101016.870100.323003.074702.17180K562SF3B4
LYARENSG00000145220.9842.618001209.30500-0.521205.136803.62710K562SRSF5
LYARENSG00000145220.91573.094801968.32470-0.323404.274702.79970K562SRSF7
LYARENSG00000145220.9938.402001220.75750-0.379502.676501.42470K562SSB
LYARENSG00000145220.91329.453303177.21910-1.256903.033501.51990K562SUPT6H
LYARENSG00000145220.9776.357001228.55620-0.662206.068504.51940K562SUPV3L1
LYARENSG00000145220.92727.463401751.993300.6385012.0705010.35360K562SYNCRIP
LYARENSG00000145220.9968.029101295.95530-0.420903.451402.65740K562TARDBP
LYARENSG00000145220.91002.823301250.09070-0.318002.630101.83270K562TIA1
LYARENSG00000145220.92221.446102909.71850-0.389403.140201.78340K562TROVE2
LYARENSG00000145220.93469.123304382.63760-0.337203.250801.71650K562UBE2L3
LYARENSG00000145220.9802.254901300.13190-0.696507.417405.67390K562UCHL5
LYARENSG00000145220.91683.417602910.59710-0.789908.588307.40820K562UPF1
LYARENSG00000145220.91640.605102490.54100-0.602204.699403.54520K562WDR3
LYARENSG00000145220.93335.664802589.632700.365103.949202.95060K562WDR43
LYARENSG00000145220.92259.119703112.95360-0.462503.054102.14300K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LYAR is not available on ENCORE database.





3 RBPs can affect the splicing of LYAR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELYARENSG00000145220.9chr4-428824542882994285347428552242917624291896-0.229000.000010.00048excludedHepG2U2AF1
SELYARENSG00000145220.9chr4-428136842814764281173428125742835094283624-0.064000.000040.00095excludedHepG2U2AF2
SELYARENSG00000145220.9chr4-428824542882994285347428552242917624291896-0.229000.000000.00000excludedHepG2U2AF2
SELYARENSG00000145220.9chr4-428824542882994285347428552242917624291896-0.134000.004610.09898excludedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LYAR is not avaliable on ENCORE database.