CISD1

General Information

Gene Name       : CISD1
Gene ID             : ENSG00000122873.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CISD1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CISD1ENSG00000122873.1130.3030.9230.61ENCSR000AEF
HepG2CISD1ENSG00000122873.1136.1253.3044.71ENCSR985KAT
K562CISD1ENSG00000122873.1182.9468.4575.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CISD1Ribo-STAMP-293TshRNACISD1-BGRSLV03-11,CISD1-BGRSLV03-12NT-BGRSLV03-1,NT-BGRSLV03-2,SubmittedENCORE2
CISD1Ribo-STAMP-293TshRNABGRSDLV02-13,BGRSDLV02-14BGRSDLV02-1,BGRSDLV02-2SubmittedENCORE2
CISD1Ribo-STAMP-293TshRNACISD1-BGRSDLV02-15dox,CISD1-BGRSDLV02-16doxCISD1-BGRSDLV02-13,CISD1-BGRSDLV02-14,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CISD1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CISD1 RNA is bound by 9 proteins.  







eCLIP assay for CISD1 is not avaliable on ENCORE database.





9 proteins are bound to CISD1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr106004743660047537+3'-UTR,intron-Proximal4.251726.92152K562PABPC4
chr106004765860047707+3'-UTR,intron-Distal5.659695.71015K562PABPC4
chr106002892460029029+5'-UTR4.2419416.30468K562DDX3X
chr106002896160028966+5'-UTR6.0253012.30838K562YBX3
chr106002898860028997+5'-UTR3.029666.79124K562YBX3
chr106002905660029105+CDS,intron-Proximal4.784595.26064K562AQR
chr106002906360029134+CDS,intron-Proximal3.334663.76553K562PRPF8
chr106002908860029174+intron-Distal,intron-Proximal4.153705.05259HepG2RBM22
chr106003471760034814+intron-Distal3.547626.22064HepG2QKI
chr106002917160029307+intron-Distal4.642048.17426HepG2DKC1
chr106002924960029321+intron-Distal4.583864.97317K562SMNDC1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CISD1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CISD1 is not available on ENCORE database.

  • 99 RBPs can affect the levels of CISD1.  








The Knockdown/knockout RNA-Seq assay for CISD1 is not available on ENCORE database.





99 RBPs can affect the gene expression of CISD1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CISD1ENSG00000122873.7299.74620436.55050-0.542404.720103.96610HepG2ACO1
CISD1ENSG00000122873.7319.56360438.62530-0.456903.394302.55610HepG2AKAP8L
CISD1ENSG00000122873.7868.88290556.559800.642505.495604.45670HepG2CALR
CISD1ENSG00000122873.7366.36520529.25180-0.530703.513402.74780HepG2CPSF6
CISD1ENSG00000122873.71053.67020722.321200.544604.349003.57930HepG2DDX3X
CISD1ENSG00000122873.7625.68970470.277300.411802.514001.54610HepG2DDX5
CISD1ENSG00000122873.7358.62720620.46090-0.790906.150805.25860HepG2DDX6
CISD1ENSG00000122873.7255.51230376.08860-0.557704.031203.19610HepG2DNAJC21
CISD1ENSG00000122873.7275.76160372.72400-0.434703.074202.39310HepG2DNAJC2
CISD1ENSG00000122873.7384.65390596.49180-0.632904.485403.74080HepG2EIF2S1
CISD1ENSG00000122873.7384.56980659.20700-0.777506.257205.30150HepG2EIF4A3
CISD1ENSG00000122873.7391.17660641.80490-0.714304.387303.53180HepG2EIF4B
CISD1ENSG00000122873.7778.70320602.945200.368903.215702.32750HepG2EIF4G1
CISD1ENSG00000122873.7486.33020720.66490-0.567405.969205.14230HepG2ETF1
CISD1ENSG00000122873.7400.21720665.07160-0.732706.196605.18830HepG2FXR1
CISD1ENSG00000122873.7441.68530616.97280-0.482202.870602.19330HepG2G3BP1
CISD1ENSG00000122873.7300.74330416.79810-0.470803.632102.52470HepG2HDGF
CISD1ENSG00000122873.7140.99720379.69110-1.4292014.3964013.10950HepG2HNRNPA1
CISD1ENSG00000122873.7394.45100541.52900-0.457202.497901.81560HepG2HNRNPF
CISD1ENSG00000122873.7462.97390624.69100-0.432202.640501.95760HepG2HNRNPK
CISD1ENSG00000122873.7451.29940627.14700-0.474702.909202.22040HepG2IGF2BP2
CISD1ENSG00000122873.7439.06070630.78850-0.522702.839101.82290HepG2KHSRP
CISD1ENSG00000122873.7298.80160399.07960-0.417503.001601.94390HepG2KIF1C
CISD1ENSG00000122873.7505.63920669.03390-0.404002.090001.53680HepG2MATR3
CISD1ENSG00000122873.7518.52330684.79870-0.401302.220001.65030HepG2NCBP2
CISD1ENSG00000122873.7370.37730609.88260-0.719505.781204.75110HepG2PABPC4
CISD1ENSG00000122873.7433.69870582.96030-0.426703.727903.04560HepG2PCBP1
CISD1ENSG00000122873.7451.70970593.16720-0.393003.221402.64020HepG2PTBP1
CISD1ENSG00000122873.7337.17220613.68880-0.8640010.533109.27060HepG2PUM2
CISD1ENSG00000122873.7516.89630642.45040-0.313702.078601.52560HepG2QKI
CISD1ENSG00000122873.7416.32150583.05150-0.485903.129702.41760HepG2RBM25
CISD1ENSG00000122873.7490.31830660.15200-0.429103.723803.11410HepG2NELFE
CISD1ENSG00000122873.7437.35890614.81670-0.491304.624203.85600HepG2RECQL
CISD1ENSG00000122873.7195.10130333.27840-0.772503.723403.02110HepG2RPS19
CISD1ENSG00000122873.7488.25290617.59360-0.339002.552301.98070HepG2SF3B4
CISD1ENSG00000122873.7340.33750435.71740-0.356402.481601.86770HepG2SMN1
CISD1ENSG00000122873.71009.63100644.621800.6472010.064909.28800HepG2SRSF1
CISD1ENSG00000122873.7458.00260571.19470-0.318602.401201.81350HepG2SRSF5
CISD1ENSG00000122873.7368.37690524.42360-0.509604.592103.91390HepG2SRSF9
CISD1ENSG00000122873.7782.78670590.739000.406004.443903.82590HepG2SSB
CISD1ENSG00000122873.7472.40940649.63180-0.459604.854004.07130HepG2SUCLG1
CISD1ENSG00000122873.7342.17490532.40480-0.637805.761604.56720HepG2TIA1
CISD1ENSG00000122873.7246.08030407.70670-0.728406.161405.46800HepG2TIAL1
CISD1ENSG00000122873.7308.06120411.29300-0.416902.989102.40820HepG2TRIM56
CISD1ENSG00000122873.7446.37030565.16880-0.340402.095201.34430HepG2TUFM
CISD1ENSG00000122873.7466.10380823.04350-0.820302.171001.30960HepG2U2AF2
CISD1ENSG00000122873.7535.73720644.05920-0.265702.071801.57960HepG2ZNF622
CISD1ENSG00000122873.7873.66170626.101400.480604.114602.63820K562AARS
CISD1ENSG00000122873.71212.527701791.53590-0.563203.820202.35900K562ABCF1
CISD1ENSG00000122873.7498.28960629.27450-0.336702.411701.87580K562AGGF1
CISD1ENSG00000122873.71720.632201362.408600.336703.232701.89150K562APOBEC3C
CISD1ENSG00000122873.7453.052101234.72110-1.4464014.3418013.15220K562AQR
CISD1ENSG00000122873.7533.31980709.43270-0.411702.572801.73270K562BOP1
CISD1ENSG00000122873.7828.779301247.77700-0.590304.285002.45900K562BUD13
CISD1ENSG00000122873.7610.24260998.17960-0.709903.100701.55800K562CKAP4
CISD1ENSG00000122873.7796.481101539.67180-0.950903.249602.08240K562CNOT7
CISD1ENSG00000122873.71013.694501306.62920-0.366203.953602.62060K562CPEB4
CISD1ENSG00000122873.7511.84780754.32530-0.559505.453404.35990K562CPSF6
CISD1ENSG00000122873.71284.623701897.89460-0.563104.672603.39310K562CELF1
CISD1ENSG00000122873.7532.45880770.76190-0.533604.984603.32670K562DDX21
CISD1ENSG00000122873.7310.41820487.28670-0.650604.437603.26440K562EFTUD2
CISD1ENSG00000122873.7729.790001059.07300-0.537203.741802.92810K562EIF2S2
CISD1ENSG00000122873.7318.35050491.07610-0.625303.265201.87260K562EXOSC5
CISD1ENSG00000122873.7939.591401287.65730-0.454602.911202.04020K562FIP1L1
CISD1ENSG00000122873.7445.34210650.54530-0.546703.880802.78260K562FTO
CISD1ENSG00000122873.7884.84110406.433901.1223017.0713015.68120K562FXR1
CISD1ENSG00000122873.7615.06050920.51950-0.581707.462905.64790K562GLRX3
CISD1ENSG00000122873.7418.19550720.19090-0.784208.387106.99890K562GPKOW
CISD1ENSG00000122873.7317.89700681.58550-1.1003016.5116014.18130K562HNRNPA1
CISD1ENSG00000122873.7266.69690685.33950-1.3616015.0048013.70050K562HNRNPC
CISD1ENSG00000122873.7408.77980611.89500-0.582004.678703.14460K562HNRNPF
CISD1ENSG00000122873.7948.920301221.97960-0.364903.195002.04980K562HNRNPL
CISD1ENSG00000122873.71865.791201059.029100.8169010.123908.10330K562HNRNPM
CISD1ENSG00000122873.7483.73660754.79930-0.641907.703806.22120K562HNRNPU
CISD1ENSG00000122873.7396.10780569.07000-0.522703.005501.92090K562IGF2BP2
CISD1ENSG00000122873.7300.34370614.96420-1.033908.570906.81560K562KRR1
CISD1ENSG00000122873.7500.40670694.84790-0.473603.037201.50170K562LIN28B
CISD1ENSG00000122873.7554.32430702.98840-0.342802.311301.51300K562METAP2
CISD1ENSG00000122873.7786.32020967.80340-0.299602.892402.06480K562MTPAP
CISD1ENSG00000122873.7542.896301075.33200-0.9860027.1783025.23570K562NSUN2
CISD1ENSG00000122873.7519.29220998.61100-0.943402.194901.33390K562PABPN1
CISD1ENSG00000122873.7655.59200474.184400.467203.113502.31710K562PRPF8
CISD1ENSG00000122873.7396.75680614.44700-0.631003.786202.70460K562PSIP1
CISD1ENSG00000122873.7992.49430581.279200.7717011.3445010.06060K562PTBP1
CISD1ENSG00000122873.71233.959201755.67220-0.508704.012602.85240K562PUM2
CISD1ENSG00000122873.7401.58230557.50930-0.473303.297302.37310K562RBM22
CISD1ENSG00000122873.7271.91470396.50150-0.544203.495901.97930K562RBM25
CISD1ENSG00000122873.7568.25740426.893400.412602.629401.57710K562SAFB
CISD1ENSG00000122873.7549.471801061.05520-0.9494019.5517017.54610K562SF3A3
CISD1ENSG00000122873.7391.09090684.94230-0.808506.894505.31400K562SF3B1
CISD1ENSG00000122873.7492.656401114.48240-1.177702.824401.50270K562SFPQ
CISD1ENSG00000122873.7261.58050369.15360-0.497002.828601.55260K562SLBP
CISD1ENSG00000122873.7466.126001048.64740-1.169702.935301.65780K562SNRNP200
CISD1ENSG00000122873.7338.62760531.30780-0.649804.157102.82430K562SRFBP1
CISD1ENSG00000122873.7731.240701087.07190-0.572009.791508.14500K562SRPK2
CISD1ENSG00000122873.7851.83390569.820300.580006.013004.97950K562SRSF1
CISD1ENSG00000122873.7441.43750687.73190-0.639605.152503.53700K562SRSF7
CISD1ENSG00000122873.7972.475701545.45550-0.668304.945203.19270K562STAU1
CISD1ENSG00000122873.7562.346101254.79280-1.157902.886701.41900K562SUPT6H
CISD1ENSG00000122873.7787.64650480.572600.712704.993803.88330K562SYNCRIP
CISD1ENSG00000122873.7265.94930576.75380-1.1168013.3021011.54800K562TARDBP
CISD1ENSG00000122873.7412.02780556.32880-0.433202.979502.12560K562TIA1
CISD1ENSG00000122873.7258.09370591.01370-1.1953012.5411010.44440K562TIAL1
CISD1ENSG00000122873.7309.48680627.70510-1.020207.447405.72320K562TRIM56
CISD1ENSG00000122873.7899.961601506.77640-0.743505.428403.34650K562TRIP6
CISD1ENSG00000122873.7294.64080418.38610-0.505903.427902.53600K562U2AF2
CISD1ENSG00000122873.7337.41040485.96230-0.526303.122002.03490K562UCHL5
CISD1ENSG00000122873.7684.270701140.19610-0.7366014.7701013.26490K562UPF1
CISD1ENSG00000122873.7631.99350829.42710-0.392202.448301.32410K562UTP3
CISD1ENSG00000122873.7567.83940975.63180-0.7809010.914709.12420K562WDR3
CISD1ENSG00000122873.7823.96110488.957000.752803.831101.89120K562XRCC6
CISD1ENSG00000122873.7734.262701391.14840-0.921907.194505.68770K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CISD1 is not available on ENCORE database.





3 RBPs can affect the splicing of CISD1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECISD1ENSG00000122873.7chr10+6003587760035972600289376002906460036876600370820.083000.000050.00751includedHepG2PRPF8
SECISD1ENSG00000122873.7chr10+6003587760035972600289376002906460036876600370820.054000.000000.00007includedK562AQR
SECISD1ENSG00000122873.7chr10+6003587760035972600289376002906460036876600370820.110000.000580.02007includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CISD1 is not avaliable on ENCORE database.