SMC3

General Information

Gene Name : SMC3
Gene ID : ENSG00000108055.9
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SMC3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SMC3	ENSG00000108055.9	61.11	55.12	58.11	ENCSR000AEF
HepG2	SMC3	ENSG00000108055.9	28.73	54.60	41.66	ENCSR985KAT
K562	SMC3	ENSG00000108055.9	38.06	42.08	40.07	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SMC3 is not avaliable on ENCORE database.

Proteins bound to RNA

SMC3 RNA is bound by 26 proteins.

CanvasJS.com

eCLIP assay for SMC3 is not avaliable on ENCORE database.

26 proteins are bound to SMC3 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr10	112364097	112364154	+	3'-UTR	5.90974	82.39023	K562	PUM2
chr10	112364058	112364097	+	3'-UTR	6.13245	78.36092	K562	PUM2
chr10	112349650	112349713	+	CDS	7.10779	33.22222	HepG2	BCLAF1
chr10	112327458	112327589	+	5'-UTR,CDS	4.59731	29.41532	K562	DDX3X
chr10	112361535	112361637	+	CDS	4.06447	22.88058	K562	UCHL5
chr10	112361571	112361631	+	CDS	4.44157	20.53678	HepG2	BCLAF1
chr10	112361565	112361637	+	CDS	4.91453	18.97452	K562	ZNF622
chr10	112362329	112362398	+	CDS	4.06957	18.19304	K562	UCHL5
chr10	112327525	112327591	+	5'-UTR,CDS,intron-Proximal	5.13824	17.94032	K562	PUM2
chr10	112357995	112358041	+	CDS	5.31414	17.45530	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 73 entries

eCLIP assay for SMC3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SMC3 is not available on ENCORE database.
123 RBPs can affect the levels of SMC3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SMC3 is not available on ENCORE database.

123 RBPs can affect the gene expression of SMC3 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SMC3	ENSG00000108055.9	1541.61750	3250.63420	-1.07630	65.09810	63.36460	HepG2	ZNF622
SMC3	ENSG00000108055.9	1859.91790	3487.18480	-0.90680	30.39800	29.04560	HepG2	RBM22
SMC3	ENSG00000108055.9	1052.39550	1847.14890	-0.81160	27.73970	25.87890	HepG2	DNAJC2
SMC3	ENSG00000108055.9	1497.32520	2484.45070	-0.73050	26.61350	25.03040	HepG2	CKAP4
SMC3	ENSG00000108055.9	1506.34500	3248.70680	-1.10880	25.37010	23.60520	HepG2	TARDBP
SMC3	ENSG00000108055.9	1657.27760	3356.02830	-1.01790	22.85320	21.39570	HepG2	BOP1
SMC3	ENSG00000108055.9	2559.47360	3938.62400	-0.62180	22.44080	21.37190	HepG2	SRFBP1
SMC3	ENSG00000108055.9	1067.63960	2020.02090	-0.91990	22.10890	20.94690	HepG2	TIAL1
SMC3	ENSG00000108055.9	1357.12550	2947.93280	-1.11910	22.13730	20.21840	HepG2	CIRBP
SMC3	ENSG00000108055.9	1853.02240	2955.63330	-0.67360	21.79870	20.20850	HepG2	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 150 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SMC3 is not available on ENCORE database.

6 RBPs can affect the splicing of SMC3 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SMC3	ENSG00000108055.9	chr10	+	112342319	112342400	112341680	112341856	112343141	112343306	-0.09000	0.00000	0.00006	excluded	K562	SF3B4
SE	SMC3	ENSG00000108055.9	chr10	+	112333464	112333503	112328695	112328771	112335093	112335161	-0.38000	0.00000	0.00000	excluded	HepG2	U2AF2
SE	SMC3	ENSG00000108055.9	chr10	+	112342319	112342400	112341680	112341856	112343141	112343306	-0.10400	0.00000	0.00000	excluded	K562	AQR
A3SS	SMC3	ENSG00000108055.9	chr10	+	112343574	112343720	112343598	112343720	112343141	112343306	0.06000	0.00000	0.00000	longer	K562	AQR
A3SS	SMC3	ENSG00000108055.9	chr10	+	112349626	112349757	112349649	112349757	112349316	112349466	0.16300	0.00000	0.00000	longer	K562	AQR
SE	SMC3	ENSG00000108055.9	chr10	+	112342319	112342400	112341680	112341856	112343141	112343306	-0.07200	0.00002	0.00071	excluded	K562	U2AF1
SE	SMC3	ENSG00000108055.9	chr10	+	112333464	112333503	112328695	112328771	112335093	112335161	-0.14500	0.00006	0.00113	excluded	K562	AQR
SE	SMC3	ENSG00000108055.9	chr10	+	112333464	112333503	112328695	112328771	112335093	112335161	-0.12300	0.00006	0.00854	excluded	K562	HNRNPUL1
SE	SMC3	ENSG00000108055.9	chr10	+	112342319	112342400	112341680	112341856	112343141	112343306	-0.07200	0.00010	0.00285	excluded	HepG2	U2AF1
SE	SMC3	ENSG00000108055.9	chr10	+	112333464	112333503	112328695	112328771	112335093	112335161	-0.18900	0.00026	0.02306	excluded	K562	HNRNPL

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SMC3

General Information

Functions

Localization

Domains (AlphaFold: SMC3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SMC3 is not avaliable on ENCORE database.

26 proteins are bound to SMC3 RNA:

eCLIP assay for SMC3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SMC3 is not available on ENCORE database.

123 RBPs can affect the gene expression of SMC3 :

The Knockdown/knockout RNA-Seq assay for SMC3 is not available on ENCORE database.

6 RBPs can affect the splicing of SMC3 :

The Knockdown/knockout RNA-Seq assay for SMC3 is not avaliable on ENCORE database.