SDHB

General Information

Gene Name       : SDHB
Gene ID             : ENSG00000117118.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SDHB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SDHBENSG00000117118.9145.22130.37137.80ENCSR000AEF
HepG2SDHBENSG00000117118.996.33106.43101.38ENCSR985KAT
K562SDHBENSG00000117118.9269.21304.85287.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SDHB is not avaliable on ENCORE database.



Proteins bound to RNA
  • SDHB RNA is bound by 14 proteins.  







eCLIP assay for SDHB is not avaliable on ENCORE database.





14 proteins are bound to SDHB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11734527617345318-3'-UTR,intron-Distal3.279887.73042K562YBX3
chr11734523117345271-3'-UTR,intron-Distal,intron-Proximal,polyA_signal4.476767.90397K562PABPC4
chr11734527117345384-3'-UTR,CDS,intron-Distal4.1399831.58653K562PABPC4
chr11734525717345305-3'-UTR,intron-Distal4.6802713.65026K562PUM2
chr11738044217380526-5'-UTR,CDS,intron-Distal,intron-Proximal3.700694.53300K562LIN28B
chr11738046317380522-5'-UTR,CDS,intron-Distal,intron-Proximal4.1589529.68729K562DDX3X
chr11738044217380532-5'-UTR,CDS,intron-Distal,intron-Proximal3.802707.33300K562FXR2
chr11737134117371364-CDS,intron-Distal3.1389913.08534K562DDX3X
chr11735522817355231-CDS,intron-Distal3.7488116.38329K562YBX3
chr11738044217380449-CDS,intron-Distal4.4814129.03191K562DDX3X
chr11735424517354345-CDS,intron-Distal3.442335.14253HepG2GRWD1
chr11735433117354360-CDS,intron-Distal3.3446910.04645K562YBX3
chr11735509417355116-CDS,intron-Distal,intron-Proximal4.0117113.79838K562YBX3
chr11735514117355170-CDS,intron-Distal,intron-Proximal3.2403010.14475K562YBX3
chr11738040917380483-CDS,intron-Distal4.619064.68690HepG2PRPF8
chr11734916617349294-CDS,intron-Distal,intron-Proximal3.5035110.61048K562SF3B4
chr11735511617355141-CDS,intron-Distal,intron-Proximal3.5063311.88183K562YBX3
chr11737136417371384-CDS,intron-Distal,intron-Proximal4.4051931.55985K562DDX3X
chr11735517017355207-CDS,intron-Distal4.0783425.53341K562YBX3
chr11735520717355217-CDS,intron-Distal3.5710019.09324K562YBX3
chr11735516517355232-CDS,intron-Distal,intron-Proximal3.458964.80070K562GRWD1
chr11738044917380463-CDS,intron-Distal4.3324132.22419K562DDX3X
chr11737125517371334-CDS,intron-Distal,intron-Proximal4.555178.22913K562RPS3
chr11735427717354360-CDS,intron-Distal4.062333.81597K562RBM15
chr11734905717349106-CDS,intron-Distal,intron-Proximal3.572516.65114HepG2PRPF8
chr11734609917346183-intron-Distal3.690896.39777K562PTBP1
chr11735494717354997-intron-Distal,intron-Proximal3.823594.00320K562AQR
chr11734618317346229-intron-Distal3.448044.50771K562PTBP1
chr11734909717349102-intron-Distal,intron-Proximal7.1650031.74969K562AQR
chr11737143417371550-intron-Distal,intron-Proximal4.358585.46313K562KHSRP
chr11735042517350468-intron-Distal,intron-Proximal4.176734.00320K562AQR
chr11734905817349097-intron-Distal,intron-Proximal7.2955334.22784K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SDHB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SDHB is not available on ENCORE database.

  • 83 RBPs can affect the levels of SDHB.  








The Knockdown/knockout RNA-Seq assay for SDHB is not available on ENCORE database.





83 RBPs can affect the gene expression of SDHB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SDHBENSG00000117118.51184.35440874.885800.436802.993002.01060HepG2ABCF1
SDHBENSG00000117118.5661.60040515.257100.360602.135601.60480HepG2BOP1
SDHBENSG00000117118.51329.88190928.263700.518604.626203.64030HepG2CIRBP
SDHBENSG00000117118.51354.714601086.700200.317904.328003.43450HepG2DAZAP1
SDHBENSG00000117118.5953.30330664.006600.521604.777103.91320HepG2DDX21
SDHBENSG00000117118.51655.507201131.162500.549405.073804.24880HepG2DDX3X
SDHBENSG00000117118.5598.40030971.67840-0.699405.809504.94360HepG2DDX6
SDHBENSG00000117118.5863.15930600.155500.524203.924102.84330HepG2EEF2
SDHBENSG00000117118.5693.07990934.11150-0.430602.852702.25100HepG2EIF2S1
SDHBENSG00000117118.5817.458601032.30960-0.336701.845101.31880HepG2EIF4A3
SDHBENSG00000117118.5809.040201072.08660-0.406104.854203.79550HepG2EIF4G1
SDHBENSG00000117118.5755.174601403.44550-0.8941021.5723020.16550HepG2ETF1
SDHBENSG00000117118.5722.54300966.18900-0.419202.687002.03080HepG2G3BP1
SDHBENSG00000117118.5439.51200642.39860-0.547602.887701.75100HepG2GRSF1
SDHBENSG00000117118.5440.42510678.96770-0.624405.477704.61130HepG2HNRNPA1
SDHBENSG00000117118.5424.06900755.21500-0.832609.139207.93600HepG2HNRNPC
SDHBENSG00000117118.5752.75430989.90420-0.395105.284004.37780HepG2HNRNPL
SDHBENSG00000117118.5278.47020521.92900-0.906305.742904.32010HepG2MTPAP
SDHBENSG00000117118.5339.28970453.72720-0.419302.060601.41060HepG2NSUN2
SDHBENSG00000117118.5640.22440955.07030-0.577004.724803.79300HepG2PABPC4
SDHBENSG00000117118.5613.82810742.60600-0.274802.111001.36310HepG2PARN
SDHBENSG00000117118.5342.18760567.95100-0.731005.614704.50670HepG2PRPF8
SDHBENSG00000117118.5749.18420998.35790-0.414204.570403.90600HepG2PTBP1
SDHBENSG00000117118.5731.417501081.27320-0.564007.157606.22170HepG2QKI
SDHBENSG00000117118.5824.875701173.01950-0.508006.525705.81160HepG2RBM22
SDHBENSG00000117118.5799.69590981.31470-0.295302.103601.51000HepG2RBM25
SDHBENSG00000117118.5851.372301111.08700-0.384104.338803.68860HepG2NELFE
SDHBENSG00000117118.5765.755601034.80760-0.434405.280504.46280HepG2RECQL
SDHBENSG00000117118.5892.79780668.113100.418105.055404.23130HepG2SAFB2
SDHBENSG00000117118.51383.39490834.201700.729602.848502.16360HepG2SF3A3
SDHBENSG00000117118.5685.698101039.44210-0.600209.041008.06580HepG2SF3B4
SDHBENSG00000117118.5971.510401324.88020-0.447607.227006.52240HepG2SRFBP1
SDHBENSG00000117118.51325.045801084.943300.288303.054402.56320HepG2SRSF1
SDHBENSG00000117118.5812.53290972.26860-0.258902.163201.53950HepG2SRSF7
SDHBENSG00000117118.5725.02880975.16370-0.427604.531403.84110HepG2TAF15
SDHBENSG00000117118.5708.442701063.69070-0.586402.423401.64360HepG2UBE2L3
SDHBENSG00000117118.56105.318604164.080100.552008.549007.33760K562AKAP8L
SDHBENSG00000117118.53068.260205648.40760-0.8804018.4956017.14430K562AQR
SDHBENSG00000117118.51435.867702057.35090-0.518905.438504.20300K562BOP1
SDHBENSG00000117118.51307.717601879.22720-0.523105.318703.74810K562CCAR1
SDHBENSG00000117118.51599.679602187.56850-0.451505.800004.67170K562CPSF6
SDHBENSG00000117118.52093.295002525.27010-0.270702.937901.84890K562CSTF2
SDHBENSG00000117118.52389.503002918.17600-0.288403.708502.15440K562DDX27
SDHBENSG00000117118.51567.385502103.82970-0.424703.706002.12790K562DHX30
SDHBENSG00000117118.55931.432004480.855700.404508.029606.40330K562DKC1
SDHBENSG00000117118.51502.687302020.79010-0.427404.052602.40530K562DNAJC21
SDHBENSG00000117118.52252.407202863.21740-0.346203.022602.06820K562EFTUD2
SDHBENSG00000117118.52973.706404580.01080-0.6231017.2125015.64360K562EIF2S2
SDHBENSG00000117118.52985.294402469.427200.273602.280201.55310K562EIF3G
SDHBENSG00000117118.56355.574107350.39960-0.209802.816801.87160K562EIF4G2
SDHBENSG00000117118.52815.154602310.961100.284603.184301.78000K562EWSR1
SDHBENSG00000117118.51860.486302681.22120-0.527205.413403.74110K562FKBP4
SDHBENSG00000117118.51758.472002225.77150-0.340002.798701.94030K562FMR1
SDHBENSG00000117118.51215.664001886.53010-0.634006.915505.40110K562FTO
SDHBENSG00000117118.53281.516502753.254200.253103.196602.55330K562FXR1
SDHBENSG00000117118.51558.365802088.60100-0.422504.401503.40620K562GPKOW
SDHBENSG00000117118.54982.708406103.11830-0.292603.207002.39560K562GRSF1
SDHBENSG00000117118.53010.524204004.74530-0.411705.539604.04280K562HNRNPA1
SDHBENSG00000117118.51385.643403086.67510-1.1555032.8730030.87630K562HNRNPC
SDHBENSG00000117118.52233.832202756.81110-0.303502.776201.63110K562HNRNPF
SDHBENSG00000117118.54255.233502909.690200.548302.501501.61830K562HNRNPM
SDHBENSG00000117118.53496.172104435.03630-0.343205.104903.87830K562HNRNPU
SDHBENSG00000117118.51187.467001897.32380-0.676108.112805.63970K562KHDRBS1
SDHBENSG00000117118.51156.985401783.37490-0.624205.194603.86250K562KRR1
SDHBENSG00000117118.51874.314403828.31640-1.0303050.8452048.19560K562MTPAP
SDHBENSG00000117118.54917.126803469.973500.502804.059002.93420K562NAA15
SDHBENSG00000117118.53388.282604253.65880-0.328209.768308.48280K562NSUN2
SDHBENSG00000117118.54844.034602947.922600.716403.696602.50500K562PABPN1
SDHBENSG00000117118.51977.094903476.04970-0.8141011.8915010.17010K562PCBP3
SDHBENSG00000117118.51798.449202666.23520-0.568109.570208.11920K562POLR2G
SDHBENSG00000117118.55795.429904015.848900.529105.716904.46530K562PPIG
SDHBENSG00000117118.56843.404808358.00040-0.288404.757703.48700K562PUM2
SDHBENSG00000117118.55171.353404129.633500.324403.175802.60090K562PUS1
SDHBENSG00000117118.55035.695104023.698600.323604.834304.07060K562RBM15
SDHBENSG00000117118.52361.624202922.36850-0.307402.640201.82070K562RBM22
SDHBENSG00000117118.53578.246704197.19320-0.230203.034402.18280K562SF3A3
SDHBENSG00000117118.51288.610901986.29210-0.624306.198704.70950K562SF3B1
SDHBENSG00000117118.51497.474002069.71500-0.466904.652702.97730K562SLBP
SDHBENSG00000117118.51756.752702394.20000-0.446604.979003.48230K562SRFBP1
SDHBENSG00000117118.53531.910504300.10760-0.283906.066604.74420K562SRPK2
SDHBENSG00000117118.52836.691503514.20630-0.309004.394702.89810K562SRSF7
SDHBENSG00000117118.52372.178003034.80420-0.355404.580802.59350K562SRSF9
SDHBENSG00000117118.51966.331002697.69630-0.456203.908502.68580K562SUPV3L1
SDHBENSG00000117118.52416.005803023.67680-0.323702.658201.96280K562TARDBP
SDHBENSG00000117118.51867.655902661.94130-0.511305.198803.87310K562TIAL1
SDHBENSG00000117118.52047.339302828.57620-0.466305.497704.05480K562TRIM56
SDHBENSG00000117118.51836.984802527.14610-0.460203.859901.73780K562TRNAU1AP
SDHBENSG00000117118.52063.915602855.17240-0.468204.708403.34020K562UCHL5
SDHBENSG00000117118.53176.157804510.24020-0.5059014.7747013.26900K562UPF1
SDHBENSG00000117118.52535.554703284.20800-0.373202.873401.64680K562UTP3
SDHBENSG00000117118.52947.034203859.27730-0.389104.970003.78080K562WDR3
SDHBENSG00000117118.53453.403804013.15130-0.216703.460102.52190K562WDR43
SDHBENSG00000117118.54753.699506363.02210-0.420705.225903.97840K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SDHB is not available on ENCORE database.





2 RBPs can affect the splicing of SDHB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESDHBENSG00000117118.5chr1-173542431735436017350335173505691735514817355231-0.140000.000000.00000excludedK562SUPV3L1
A3SSSDHBENSG00000117118.5chr1-1735046717350630173504671735056917354243173543600.075000.000000.00000longerK562AQR
MXESDHBENSG00000117118.5chr1-17355148173552311737125517371447173542431735436017380442173805020.237000.001810.015261includedK562AQR
MXESDHBENSG00000117118.5chr1-1735033517350478173542431735436017349102173492251735514817355231-0.558000.000000.000002includedK562AQR
MXESDHBENSG00000117118.5chr1-1735033517350569173542431735436017349102173492251735514817355231-0.546000.000000.000002includedK562AQR
MXESDHBENSG00000117118.5chr1-1735514817355231173595541735964017350467173505691737125517371383-0.107000.000000.000002includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SDHB is not avaliable on ENCORE database.