REXO2

General Information

Gene Name : REXO2
Gene ID : ENSG00000076043.9
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: REXO2)

Not Available

Antibody Validation

Bethyl Labs: A304-812A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	REXO2	ENSG00000076043.9	1.66	3.33	2.50	ENCSR000AEF
HepG2	REXO2	ENSG00000076043.9	49.50	68.51	59.01	ENCSR985KAT
K562	REXO2	ENSG00000076043.9	129.10	154.97	142.03	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	REXO2-BGHcLV32-HepG2	ENCSR199WMC	REXO2	HepG2	Released		ENCSR232ERY	CRISPR	KD% = 64.9,73.6

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
REXO2	ENCAB364BXM	A304-812A	1			Released, ENCODE4	BGHcLV32-29, Released, ENCODE4
REXO2		A304-812A	3				BGHcLV32-29, Released, ENCODE4	BGKcLV46-55, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
REXO2	K562	CRISPR			BGKcLV30-31,BGKcLV30-32	BGKcLV30-1,BGKcLV30-2	30.4,33.0	NotSatisfied	ENCODE4
REXO2	K562	CRISPR			BGKcLV35-31,BGKcLV35-32	BGKcLV35-1,BGKcLV35-2	45.8,35.5	NotSatisfied	ENCORE2
REXO2	K562	CRISPR			BGKcLV44-55,BGKcLV44-56	BGKcLV44-1,BGKcLV44-2	0.0,0.0	NotSatisfied	ENCORE2
REXO2	K562	CRISPR			REXO2-BGKcLV46-55,REXO2-BGKcLV46-56	NT-BGKcLV46-1,NT-BGKcLV46-2	56.7,64.9	Submitting	ENCORE2
REXO2	K562	CRISPR			BGKcLV46-57,BGKcLV46-58	BGKcLV46-1,BGKcLV46-2	27.9,32.7	NotSatisfied	ENCORE2
REXO2	HepG2	CRISPR	ENCSR199WMC	ENCSR232ERY	REXO2-BGHcLV32-29,REXO2-BGHcLV32-30	NT-BGHcLV32-1,NT-BGHcLV32-2	64.9,73.6	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
REXO2	Product_ID: A304-812A Lot_ID: 3 Source: Bethyl Labs Target Name: REXO2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for REXO2 is not avaliable on ENCORE database.

Proteins bound to RNA

REXO2 RNA is bound by 24 proteins.

CanvasJS.com

eCLIP assay for REXO2 is not avaliable on ENCORE database.

24 proteins are bound to REXO2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	114310284	114310367	+	CDS,intron-Distal	4.09368	53.23616	K562	DDX3X
chr11	114310206	114310284	+	5'-UTR,CDS,intron-Distal	4.80373	33.54068	K562	DDX3X
chr11	114310270	114310372	+	CDS,intron-Distal	3.32434	25.94409	K562	FTO
chr11	114310257	114310361	+	CDS,intron-Distal	4.11423	18.21994	HepG2	DDX3X
chr11	114320760	114320815	+	3'-UTR	3.99318	16.22507	K562	TIA1
chr11	114320751	114320772	+	3'-UTR	3.34205	15.19846	K562	YBX3
chr11	114320772	114320799	+	3'-UTR	3.25036	14.86659	K562	YBX3
chr11	114320870	114320960	+	3'-UTR	3.59136	14.74110	K562	PABPC4
chr11	114320752	114320826	+	3'-UTR	4.49856	14.60396	K562	RBM15
chr11	114310378	114310397	+	CDS,intron-Distal	4.73392	13.89420	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 47 entries

eCLIP assay for REXO2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for REXO2 is not available on ENCORE database.
95 RBPs can affect the levels of REXO2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for REXO2 is not available on ENCORE database.

95 RBPs can affect the gene expression of REXO2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
REXO2	ENSG00000076043.5	710.03760	1836.87420	-1.37130	36.64110	34.55210	K562	HNRNPC
REXO2	ENSG00000076043.5	2132.19370	1217.88460	0.80790	25.80510	24.67720	HepG2	SRFBP1
REXO2	ENSG00000076043.5	1401.64210	746.86490	0.90810	25.70540	24.28370	HepG2	ACO1
REXO2	ENSG00000076043.5	2019.08290	1078.30060	0.90480	24.09010	22.86240	HepG2	RBM22
REXO2	ENSG00000076043.5	398.40850	1061.39610	-1.41360	21.51180	19.91110	HepG2	GPKOW
REXO2	ENSG00000076043.5	574.85890	1057.38360	-0.87920	19.35080	18.25680	HepG2	SSB
REXO2	ENSG00000076043.5	456.78980	1002.59860	-1.13410	17.42240	15.81870	HepG2	SF3B1
REXO2	ENSG00000076043.5	389.85400	898.10870	-1.20400	17.27350	15.59420	HepG2	NSUN2
REXO2	ENSG00000076043.5	1142.67760	695.38100	0.71640	16.41960	15.36550	HepG2	ZNF622
REXO2	ENSG00000076043.5	1657.08980	2928.31550	-0.82140	14.49270	13.29780	K562	AQR
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 114 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for REXO2 is not available on ENCORE database.

20 RBPs can affect the splicing of REXO2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	REXO2	ENSG00000076043.5	chr11	+	114315262	114315374	114314577	114314655	114316700	114316809	-0.10800	0.00000	excluded	K562	SF3B4
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316700	114316809	114320567	114320778	-0.22600	0.00000	excluded	K562	SF3B4
SE	REXO2	ENSG00000076043.5	chr11	+	114315262	114315374	114311377	114311461	114316700	114316809	-0.26100	0.00000	excluded	HepG2	U2AF1
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316664	114316809	114320567	114320761	-0.08500	0.00000	excluded	K562	AQR
SE	REXO2	ENSG00000076043.5	chr11	+	114315262	114315374	114311377	114311461	114316700	114316809	-0.08900	0.00000	excluded	K562	PUS1
SE	REXO2	ENSG00000076043.5	chr11	+	114311377	114311461	114310156	114310397	114314577	114314929	-0.12100	0.00001	excluded	K562	EFTUD2
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316700	114316809	114320567	114320639	-0.08700	0.00005	excluded	K562	U2AF1
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316700	114316809	114320567	114320761	-0.05800	0.00032	excluded	K562	TARDBP
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316700	114316809	114320567	114320778	-0.07600	0.00000	excluded	K562	HNRNPU
SE	REXO2	ENSG00000076043.5	chr11	+	114318547	114318601	114316700	114316809	114320567	114320778	-0.20400	0.00000	excluded	K562	SF3B1

Showing 1 to 10 of 41 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

REXO2

General Information

Functions

Localization

Domains (AlphaFold: REXO2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for REXO2 is not avaliable on ENCORE database.

24 proteins are bound to REXO2 RNA:

eCLIP assay for REXO2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for REXO2 is not available on ENCORE database.

95 RBPs can affect the gene expression of REXO2 :

The Knockdown/knockout RNA-Seq assay for REXO2 is not available on ENCORE database.

20 RBPs can affect the splicing of REXO2 :

The Knockdown/knockout RNA-Seq assay for REXO2 is not avaliable on ENCORE database.