POLD2

General Information

Gene Name       : POLD2
Gene ID             : ENSG00000106628.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: POLD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLD2ENSG00000106628.1039.0080.1259.56ENCSR000AEF
HepG2POLD2ENSG00000106628.10115.0273.8194.41ENCSR985KAT
K562POLD2ENSG00000106628.10180.10154.67167.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLD2 RNA is bound by 22 proteins.  







eCLIP assay for POLD2 is not avaliable on ENCORE database.





22 proteins are bound to POLD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr74415436344154434-3'-UTR,CDS,intron-Distal,intron-Proximal4.962705.45041K562PUM2
chr74415438444154545-3'-UTR,CDS,intron-Distal3.558879.39239HepG2LARP4
chr74416165844161708-5'-UTR,intron-Distal,intron-Proximal4.269256.57313K562PABPC4
chr74416309744163110-5'-UTR,intron-Distal,intron-Proximal6.0393712.64691K562AQR
chr74416303044163056-5'-UTR,intron-Distal3.404326.21987K562AQR
chr74416167644161728-5'-UTR,intron-Distal,intron-Proximal3.188275.28960K562AQR
chr74416306744163097-5'-UTR,intron-Distal,intron-Proximal4.9997517.02742K562AQR
chr74416165544161739-5'-UTR,intron-Distal,intron-Proximal4.374155.94114HepG2BUD13
chr74416301044163079-5'-UTR,intron-Distal5.746657.66714HepG2EFTUD2
chr74416305644163067-5'-UTR,intron-Distal3.331155.75231K562AQR
chr74416310844163134-5'-UTR,intron-Distal,intron-Proximal4.031725.23852K562DDX3X
chr74415754244157582-CDS,intron-Distal3.579676.08728K562METAP2
chr74415673544156828-CDS,intron-Distal,intron-Proximal3.466166.13978HepG2PPIG
chr74415442944154475-CDS,intron-Distal3.041244.54958K562PABPC4
chr74415572444155758-CDS,intron-Distal3.121067.59396K562YBX3
chr74415758244157648-CDS,intron-Distal3.978559.81860K562METAP2
chr74415450644154526-CDS,intron-Distal4.2850813.84651K562YBX3
chr74415438744154482-CDS,intron-Distal4.197548.03807K562RBM15
chr74416139344161453-CDS,intron-Distal,intron-Proximal5.072516.01989HepG2PRPF8
chr74415682244156938-CDS,intron-Distal,intron-Proximal3.314374.85257K562FUS
chr74415683444156874-CDS,intron-Distal,intron-Proximal3.615758.38544K562SF3B4
chr74415443444154441-CDS,intron-Distal3.1657115.30645K562YBX3
chr74415453644154544-CDS,intron-Distal3.5075310.06536K562YBX3
chr74416141844161466-CDS,intron-Distal,intron-Proximal4.485233.79199HepG2PPIG
chr74415683344156903-CDS,intron-Distal,intron-Proximal4.781985.54524HepG2SF3B4
chr74415608944156105-CDS,intron-Distal3.161856.77366K562YBX3
chr74415450644154548-CDS,intron-Distal4.118126.08151K562BUD13
chr74415577944155833-CDS,intron-Distal,intron-Proximal4.1276514.27079K562YBX3
chr74415439344154484-CDS,intron-Distal5.276818.46144K562METAP2
chr74415598744156043-CDS,intron-Distal,intron-Proximal4.252465.64484HepG2PRPF8
chr74415759144157623-CDS,intron-Distal3.185979.39224K562YBX3
chr74415447544154519-CDS,intron-Distal3.047176.47235K562PABPC4
chr74415498044155047-CDS,intron-Distal,intron-Proximal3.9574411.83863K562SF3B4
chr74415754344157651-CDS,intron-Distal3.101486.23779HepG2PPIG
chr74415607244156164-CDS,intron-Distal,intron-Proximal4.5333831.37426K562SF3B4
chr74416154144161600-CDS,intron-Distal,intron-Proximal3.320755.10345K562METAP2
chr74415489344154904-CDS,intron-Distal,intron-Proximal4.0410714.01820K562YBX3
chr74415533144155389-CDS,intron-Distal,intron-Proximal4.309485.05356HepG2PRPF8
chr74415449044154497-CDS,intron-Distal3.645814.74241K562YBX3
chr74415490444154921-CDS,intron-Distal4.1980815.33733K562YBX3
chr74415756044157640-CDS,intron-Distal3.557969.86075K562DDX24
chr74415585244155944-CDS,intron-Distal,intron-Proximal3.696576.34662HepG2PRPF8
chr74415754744157591-CDS,intron-Distal3.164439.60340K562YBX3
chr74415444144154464-CDS,intron-Distal3.5078818.14577K562YBX3
chr74415539444155469-CDS,intron-Distal,intron-Proximal3.824216.82493K562DDX24
chr74415489344154972-CDS,intron-Distal,intron-Proximal3.265724.22960K562SND1
chr74415647544156509-CDS,intron-Distal,intron-Proximal3.503674.17219K562METAP2
chr74415492144154943-CDS,intron-Distal3.3698412.61766K562YBX3
chr74415489344154977-CDS,intron-Distal,intron-Proximal3.528803.27682HepG2LARP4
chr74415452644154536-CDS,intron-Distal4.1421013.19940K562YBX3
chr74415446444154475-CDS,intron-Distal3.8307318.21300K562YBX3
chr74415636944156409-intron-Distal,intron-Proximal4.895795.26064K562AQR
chr74415706944157109-intron-Distal,intron-Proximal4.289333.71613K562UCHL5
chr74415611644156164-intron-Distal,intron-Proximal5.139458.74981HepG2SF3B4
chr74415704444157140-intron-Distal,intron-Proximal3.094993.57774K562EWSR1
chr74415687444156898-intron-Distal,intron-Proximal4.5237110.68651K562SF3B4
chr74415955644159616-intron-Distal3.178853.71597K562MATR3
chr74415704444157116-intron-Distal,intron-Proximal4.303899.53524K562DDX24
chr74415613744156159-intron-Distal,intron-Proximal3.284413.13705K562BUD13
chr74415697844157040-intron-Distal,intron-Proximal3.862944.11145K562FUS
chr74415504444155101-intron-Distal,intron-Proximal3.469183.57857HepG2SF3B4
chr74415707044157159-intron-Distal,intron-Proximal3.321263.51554HepG2PRPF4
chr74415457044154595-intron-Distal4.575184.26208K562SF3B4
chr74415685444156924-intron-Distal,intron-Proximal4.421934.02846K562HNRNPM
chr74415773744157785-intron-Distal,intron-Proximal3.930434.22551K562SF3B4
chr74415703944157125-intron-Distal,intron-Proximal3.715026.07730K562CSTF2T
chr74415685544156906-intron-Distal,intron-Proximal3.611086.37739K562BUD13
chr74415504744155096-intron-Distal,intron-Proximal4.885339.13098K562SF3B4
chr74416116644161231-intron-Distal4.816736.45599K562PRPF8
chr74415531544155361-intron-Distal,intron-Proximal4.221836.48405K562AQR
chr74415481644154887-intron-Distal,intron-Proximal3.210814.38107K562AQR
chr74415522344155264-intron-Distal,intron-Proximal3.254963.13705K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLD2 is not available on ENCORE database.

  • 103 RBPs can affect the levels of POLD2.  








The Knockdown/knockout RNA-Seq assay for POLD2 is not available on ENCORE database.





103 RBPs can affect the gene expression of POLD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLD2ENSG00000106628.6751.46430952.15730-0.341502.338401.34900HepG2AATF
POLD2ENSG00000106628.61021.065101248.96140-0.290702.488501.90660HepG2ACO1
POLD2ENSG00000106628.6587.52100982.52140-0.741803.783502.74660HepG2BCLAF1
POLD2ENSG00000106628.61368.785601696.54210-0.309702.955901.68530HepG2BUD13
POLD2ENSG00000106628.6907.031501478.11820-0.704504.320603.38180HepG2CALR
POLD2ENSG00000106628.61084.480101371.76010-0.339002.318301.60540HepG2CIRBP
POLD2ENSG00000106628.6795.357701050.19200-0.401003.236902.50690HepG2DDX21
POLD2ENSG00000106628.6681.766001027.96410-0.592406.877505.44740HepG2DDX24
POLD2ENSG00000106628.61349.942701671.47560-0.308201.852101.32950HepG2DDX3X
POLD2ENSG00000106628.6767.276601112.06700-0.535402.707301.94010HepG2DDX55
POLD2ENSG00000106628.6721.43280972.37200-0.430603.591402.48170HepG2DHX30
POLD2ENSG00000106628.61208.52040999.321800.274103.318602.61630HepG2DNAJC2
POLD2ENSG00000106628.6639.97610967.30120-0.595904.289502.89760HepG2AGO1
POLD2ENSG00000106628.6488.250601380.28700-1.4993023.8465022.22060HepG2EIF2S1
POLD2ENSG00000106628.6739.62800991.32570-0.422602.935002.00760HepG2EIF3D
POLD2ENSG00000106628.61192.925101525.17440-0.354502.251401.67310HepG2EIF4A3
POLD2ENSG00000106628.61036.351501623.40310-0.6475013.1326011.57490HepG2EIF4G1
POLD2ENSG00000106628.61675.708602196.79900-0.390606.898906.02090HepG2ETF1
POLD2ENSG00000106628.6547.298601154.32100-1.076603.928502.71620HepG2FTO
POLD2ENSG00000106628.61168.230601523.45540-0.383003.712402.80970HepG2FUBP3
POLD2ENSG00000106628.61114.839001427.74610-0.356902.334701.72090HepG2G3BP1
POLD2ENSG00000106628.6605.759301044.68950-0.786302.717201.36410HepG2HLTF
POLD2ENSG00000106628.61050.709201512.25080-0.525308.647707.17160HepG2HNRNPA2B1
POLD2ENSG00000106628.61297.141201498.85020-0.208502.277601.65800HepG2HNRNPL
POLD2ENSG00000106628.6761.92250536.517400.505903.091801.81590HepG2KHDRBS1
POLD2ENSG00000106628.6928.088901539.99740-0.730607.378906.32170HepG2MAGOH
POLD2ENSG00000106628.61289.441701850.38740-0.521106.275505.10270HepG2MSI2
POLD2ENSG00000106628.6734.790701105.23840-0.589003.472802.63330HepG2NSUN2
POLD2ENSG00000106628.61039.342701411.08890-0.441103.393802.59940HepG2PABPC4
POLD2ENSG00000106628.6544.39150857.33080-0.655204.016503.06570HepG2PRPF8
POLD2ENSG00000106628.61186.775001560.67840-0.395105.858905.12230HepG2PTBP1
POLD2ENSG00000106628.61206.741801652.21150-0.453305.543104.60770HepG2PUM2
POLD2ENSG00000106628.61503.721901272.114900.241202.316601.74010HepG2PUS1
POLD2ENSG00000106628.61016.750301690.35310-0.7334014.2511012.99010HepG2QKI
POLD2ENSG00000106628.6548.71890993.45530-0.856403.295902.52900HepG2RAVER1
POLD2ENSG00000106628.61518.227302130.86800-0.489107.191105.89780HepG2RBM15
POLD2ENSG00000106628.61011.496901836.09430-0.8601021.3652020.19880HepG2RBM22
POLD2ENSG00000106628.6864.068501534.06630-0.8281010.982109.70020HepG2RBM25
POLD2ENSG00000106628.61484.506201736.92410-0.226602.388801.87990HepG2NELFE
POLD2ENSG00000106628.61316.772201617.63810-0.296903.655802.96030HepG2RECQL
POLD2ENSG00000106628.61000.647501602.07690-0.679009.280108.14730HepG2RPLP0
POLD2ENSG00000106628.6638.47800976.65880-0.613202.285701.42550HepG2RPS10
POLD2ENSG00000106628.6516.88970848.02470-0.714204.556903.57740HepG2RRP9
POLD2ENSG00000106628.6742.839601233.56130-0.731704.442703.56740HepG2SF3B1
POLD2ENSG00000106628.61017.105401624.95170-0.6759014.8607013.65750HepG2SF3B4
POLD2ENSG00000106628.61371.976901167.938500.232202.706202.06700HepG2SMN1
POLD2ENSG00000106628.6557.478801372.58350-1.2999010.153308.66020HepG2SNRNP70
POLD2ENSG00000106628.6641.942102073.75990-1.6917091.1665089.33100HepG2SRFBP1
POLD2ENSG00000106628.61351.813101696.06340-0.327304.152803.60240HepG2SRSF1
POLD2ENSG00000106628.6657.241001327.55590-1.014305.567304.10650HepG2SRSF3
POLD2ENSG00000106628.61214.304101461.03180-0.266903.134802.40010HepG2SRSF7
POLD2ENSG00000106628.6657.886501379.80840-1.0686033.1553031.65310HepG2SRSF9
POLD2ENSG00000106628.6563.24040928.52460-0.721202.977601.72770HepG2SUB1
POLD2ENSG00000106628.61163.903401543.80850-0.407504.502503.31750HepG2SUPT6H
POLD2ENSG00000106628.6521.456701106.88920-1.085906.613505.63720HepG2SUPV3L1
POLD2ENSG00000106628.61089.107401524.39280-0.485104.805704.10000HepG2TAF15
POLD2ENSG00000106628.61940.724601188.402600.707502.513801.49250HepG2TBRG4
POLD2ENSG00000106628.6507.40400741.81380-0.547902.306001.38930HepG2TFIP11
POLD2ENSG00000106628.6996.675201400.81030-0.491105.978504.75850HepG2TIA1
POLD2ENSG00000106628.6876.062201092.71270-0.318802.609802.12150HepG2TIAL1
POLD2ENSG00000106628.61428.067801102.589400.373105.127604.40780HepG2TRIM56
POLD2ENSG00000106628.6855.280601956.11290-1.1935016.9481015.34050HepG2U2AF1
POLD2ENSG00000106628.61143.766701610.72850-0.493903.063102.18440HepG2UBE2L3
POLD2ENSG00000106628.61219.279301684.30530-0.466108.604307.48560HepG2UPF1
POLD2ENSG00000106628.62052.455501626.133600.335805.286104.50260HepG2UTP3
POLD2ENSG00000106628.61196.492101639.41110-0.454408.668207.58950HepG2ZC3H8
POLD2ENSG00000106628.63820.416705348.47050-0.485403.527602.13110K562ABCF1
POLD2ENSG00000106628.68217.246105750.176200.5149016.7038015.43350K562AGGF1
POLD2ENSG00000106628.62014.221804672.45750-1.2140030.7781029.01650K562AQR
POLD2ENSG00000106628.61780.971802639.61820-0.567706.812605.42600K562BOP1
POLD2ENSG00000106628.62331.330702806.60580-0.267702.436001.69620K562CPSF6
POLD2ENSG00000106628.67231.183008390.79870-0.214602.581201.63920K562CELF1
POLD2ENSG00000106628.64837.463906026.20930-0.317005.967205.06220K562DDX47
POLD2ENSG00000106628.67644.725906438.713400.247603.452402.45940K562DKC1
POLD2ENSG00000106628.62739.409903525.66710-0.364003.410501.90900K562DNAJC21
POLD2ENSG00000106628.61826.125802405.94630-0.397802.273301.44640K562EFTUD2
POLD2ENSG00000106628.63145.430104044.51070-0.362706.342305.31880K562EIF2S2
POLD2ENSG00000106628.61952.458301353.862400.528108.829307.40880K562EIF3G
POLD2ENSG00000106628.61754.685002617.17380-0.576807.968206.57410K562EIF4A3
POLD2ENSG00000106628.65700.692306823.29460-0.259304.131202.98890K562EIF4G2
POLD2ENSG00000106628.63018.259402284.508400.401705.763703.76640K562EWSR1
POLD2ENSG00000106628.65647.363803845.280200.554406.190504.88680K562FIP1L1
POLD2ENSG00000106628.62513.704903280.22120-0.384003.270402.02610K562FKBP4
POLD2ENSG00000106628.61852.112402855.78200-0.624708.510506.96920K562FMR1
POLD2ENSG00000106628.61412.856902420.58810-0.776708.895407.16730K562FTO
POLD2ENSG00000106628.6444.148701345.24530-1.5988011.227509.61040K562G3BP2
POLD2ENSG00000106628.62035.100402679.56520-0.396904.196503.22400K562GPKOW
POLD2ENSG00000106628.61891.788703774.98450-0.9967023.8236022.14210K562HNRNPC
POLD2ENSG00000106628.63139.033002080.433700.593302.302501.39160K562IGF2BP2
POLD2ENSG00000106628.61337.734302288.15240-0.774407.664406.02200K562KRR1
POLD2ENSG00000106628.67309.438506078.295400.266002.300501.34980K562MAK16
POLD2ENSG00000106628.62118.360002615.57690-0.304202.847201.95680K562METAP2
POLD2ENSG00000106628.66002.288107272.78280-0.277002.686601.57520K562MSI2
POLD2ENSG00000106628.64035.933904938.85210-0.291305.704304.57020K562MTPAP
POLD2ENSG00000106628.64823.272205487.61410-0.186204.101703.21260K562NSUN2
POLD2ENSG00000106628.66069.192103446.809900.816104.147202.87120K562PABPN1
POLD2ENSG00000106628.63939.433805720.90260-0.538305.894004.67410K562PCBP3
POLD2ENSG00000106628.63032.415304387.98380-0.533109.796908.32690K562POLR2G
POLD2ENSG00000106628.65453.890404365.638700.321002.007101.31220K562PPIG
POLD2ENSG00000106628.61581.569702341.28410-0.565903.709102.84030K562PRPF8
POLD2ENSG00000106628.65059.505507444.59180-0.557209.276607.76300K562PUF60
POLD2ENSG00000106628.66239.550307919.46670-0.344005.307203.79250K562PUM1
POLD2ENSG00000106628.66637.976407758.51400-0.225003.324702.27140K562PUM2
POLD2ENSG00000106628.66904.400105781.608000.255903.299702.66110K562RBM15
POLD2ENSG00000106628.64136.697105414.71720-0.388405.300904.19840K562SF3A3
POLD2ENSG00000106628.61245.613202548.55320-1.0328016.1567013.76170K562SF3B1
POLD2ENSG00000106628.64283.163302928.523400.548404.381303.00580K562SRFBP1
POLD2ENSG00000106628.64673.728405547.48050-0.247305.190203.95320K562SRPK2
POLD2ENSG00000106628.63033.193802080.841200.543602.575901.89030K562SRSF1
POLD2ENSG00000106628.63264.672802376.302200.458103.073201.94960K562SRSF4
POLD2ENSG00000106628.61557.341902265.77750-0.540903.579202.40790K562SUPV3L1
POLD2ENSG00000106628.62972.709202031.056600.549401.988401.30200K562TIA1
POLD2ENSG00000106628.63077.279101994.308900.625702.789301.69230K562TRA2A
POLD2ENSG00000106628.64344.995203459.836700.328603.225202.18530K562TRIM56
POLD2ENSG00000106628.6869.555501302.82200-0.583302.317901.32830K562U2AF1
POLD2ENSG00000106628.6849.185501345.91030-0.664405.206904.11060K562U2AF2
POLD2ENSG00000106628.64086.117405818.62520-0.5099011.5822010.23860K562UPF1
POLD2ENSG00000106628.63996.683305335.58370-0.416803.666102.27320K562UTP3
POLD2ENSG00000106628.64138.009004978.82740-0.266902.693301.82750K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLD2 is not available on ENCORE database.





5 RBPs can affect the splicing of POLD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPOLD2ENSG00000106628.6chr7-441564154415661444156028441561094415673144156846-0.078000.001860.03464excludedK562SF3B4
SEPOLD2ENSG00000106628.6chr7-441557134415580844155401441554924415602844156109-0.069000.000310.00769excludedHepG2U2AF1
SEPOLD2ENSG00000106628.6chr7-441572174415734144156661441568464416143244161708-0.075000.000020.00350excludedK562SUPV3L1
SEPOLD2ENSG00000106628.6chr7-4416188044162058441616864416170844163109441631310.260000.000330.00796includedK562U2AF2
A3SSPOLD2ENSG00000106628.6chr7-4415438344154569441543834415454444154893441550460.065000.000000.00000longerK562AQR
A3SSPOLD2ENSG00000106628.6chr7-4415602844156181441560284415610944156415441566140.073000.000080.00069longerK562AQR
A3SSPOLD2ENSG00000106628.6chr7-4415489344155046441548934415499544155364441555210.056000.000000.00000longerK562AQR
A3SSPOLD2ENSG00000106628.6chr7-4415536444155521441553644415549244155713441558710.056000.000000.00000longerK562AQR
A5SSPOLD2ENSG00000106628.6chr7-441553644415549244155467441554924415489344154995-0.126000.000000.00000shorterK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POLD2 is not avaliable on ENCORE database.