EXO1

General Information

Gene Name : EXO1
Gene ID : ENSG00000174371.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EXO1)

Not Available

Antibody Validation

View validation images for all EXO1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EXO1	ENSG00000174371.16	25.22	22.92	24.07	ENCSR000AEF
HepG2	EXO1	ENSG00000174371.16	11.68	21.28	16.48	ENCSR985KAT
K562	EXO1	ENSG00000174371.16	75.65	78.25	76.95	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
EXO1		A302-640A	1					BGKcLV40-33, Submitted, ENCORE2
EXO1		A302-639A	1					BGKcLV40-33, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
EXO1	K562	CRISPR			EXO1-BGKcLV40-33,EXO1-BGKcLV40-34	NT-BGKcLV40-1,NT-BGKcLV40-2	94.1,81.5	Submitting	ENCORE2
EXO1	HepG2	CRISPR			BGHcLV41-53,BGHcLV41-54	BGHcLV41-1,BGHcLV41-2	NO CLEAR BAND ON THE POSITON,	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
EXO1	Product_ID: A302-640A Lot_ID: 1 Source: Bethyl Labs Target Name: EXO1-human
EXO1	Product_ID: A302-639A Lot_ID: 1 Source: Bethyl Labs Target Name: EXO1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EXO1 is not avaliable on ENCORE database.

Proteins bound to RNA

EXO1 RNA is bound by 24 proteins.

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eCLIP assay for EXO1 is not avaliable on ENCORE database.

24 proteins are bound to EXO1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	242052769	242052842	+	3'-UTR,CDS,intron-Distal	4.82164	23.52250	K562	PUM2
chr1	242015591	242015675	+	CDS,intron-Distal,intron-Proximal	3.36361	15.32516	K562	PUM2
chr1	242026126	242026216	+	intron-Distal	6.23356	14.44342	K562	QKI
chr1	242012186	242012217	+	5'-UTR	3.80455	13.89964	K562	YBX3
chr1	242012044	242012110	+	5'-UTR	3.19243	12.64180	K562	UCHL5
chr1	242013752	242013820	+	CDS	3.49476	12.48200	K562	ZNF622
chr1	242011689	242011740	+	intron-Distal,intron-Proximal	6.17789	11.56697	K562	AQR
chr1	242020599	242020674	+	CDS,intron-Proximal	4.89113	11.02762	K562	SF3B4
chr1	242021928	242021986	+	CDS,intron-Proximal	3.52608	10.87664	K562	ZNF622
chr1	242042384	242042420	+	CDS	4.03289	10.87034	K562	RBM15
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 58 entries

eCLIP assay for EXO1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EXO1 is not available on ENCORE database.
133 RBPs can affect the levels of EXO1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EXO1 is not available on ENCORE database.

133 RBPs can affect the gene expression of EXO1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EXO1	ENSG00000174371.12	36.85660	466.72000	-3.66260	88.62140	86.68750	HepG2	ZNF622
EXO1	ENSG00000174371.12	27.42620	540.97580	-4.30190	64.65040	62.58120	HepG2	BOP1
EXO1	ENSG00000174371.12	985.03910	3043.97270	-1.62770	59.68640	57.07380	K562	HNRNPC
EXO1	ENSG00000174371.12	43.70360	451.45060	-3.36870	58.72120	56.58340	HepG2	RPLP0
EXO1	ENSG00000174371.12	71.09390	468.81330	-2.72120	55.49570	53.99530	HepG2	SRFBP1
EXO1	ENSG00000174371.12	40.05590	359.70230	-3.16670	39.95890	37.98910	HepG2	SUPV3L1
EXO1	ENSG00000174371.12	80.68900	415.07870	-2.36290	38.41910	36.92550	HepG2	RBM22
EXO1	ENSG00000174371.12	125.57340	523.73970	-2.06030	28.90260	27.03320	HepG2	TARDBP
EXO1	ENSG00000174371.12	62.59840	299.85610	-2.26010	28.15470	26.86820	HepG2	TIAL1
EXO1	ENSG00000174371.12	125.47170	537.20630	-2.09810	24.98640	23.40280	HepG2	HNRNPLL
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 163 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EXO1 is not available on ENCORE database.

39 RBPs can affect the splicing of EXO1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	EXO1	ENSG00000174371.12	chr1	+	242012410	242012518			242012252	242012329	242013710	242013888	-0.20300	0.00002	excluded	K562	AQR
SE	EXO1	ENSG00000174371.12	chr1	+	242013710	242013888			242012429	242012518	242015593	242015713	-0.10700	0.00000	excluded	K562	PUS1
SE	EXO1	ENSG00000174371.12	chr1	+	242012410	242012518			242012252	242012329	242013710	242013888	-0.33700	0.00000	excluded	K562	EFTUD2
SE	EXO1	ENSG00000174371.12	chr1	+	242012410	242012518			242012252	242012329	242013710	242013888	-0.22200	0.00007	excluded	K562	U2AF2
SE	EXO1	ENSG00000174371.12	chr1	+	242012410	242012518			242012252	242012329	242013710	242013888	-0.40600	0.00000	excluded	K562	PTBP1
SE	EXO1	ENSG00000174371.12	chr1	+	242029886	242030033			242024707	242024804	242030131	242030357	0.56400	0.00000	included	K562	HNRNPC
A3SS	EXO1	ENSG00000174371.12	chr1	+	242035333	242035580			242035336	242035580	242030131	242030357	0.09900	0.00008	longer	K562	SBDS
A3SS	EXO1	ENSG00000174371.12	chr1	+	242035333	242035580			242035336	242035580	242030131	242030357	0.11500	0.00009	longer	K562	HNRNPL
A3SS	EXO1	ENSG00000174371.12	chr1	+	242035333	242035580			242035336	242035580	242030131	242030357	0.09900	0.01061	longer	K562	AARS
MXE	EXO1	ENSG00000174371.12	chr1	+	242013710	242013888	242015593	242015713	242012032	242012329	242016659	242016783	0.22200	0.00001	1included	K562	PTBP1

Showing 1 to 10 of 92 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EXO1

General Information

Functions

Localization

Domains (AlphaFold: EXO1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EXO1 is not avaliable on ENCORE database.

24 proteins are bound to EXO1 RNA:

eCLIP assay for EXO1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EXO1 is not available on ENCORE database.

133 RBPs can affect the gene expression of EXO1 :

The Knockdown/knockout RNA-Seq assay for EXO1 is not available on ENCORE database.

39 RBPs can affect the splicing of EXO1 :

The Knockdown/knockout RNA-Seq assay for EXO1 is not avaliable on ENCORE database.