POLN

General Information

Gene Name       : POLN
Gene ID             : ENSG00000130997.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: POLN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLNENSG00000130997.160.850.330.59ENCSR000AEF
HepG2POLNENSG00000130997.160.180.150.16ENCSR985KAT
K562POLNENSG00000130997.160.240.100.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLN is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLN RNA is bound by 14 proteins.  







eCLIP assay for POLN is not avaliable on ENCORE database.





14 proteins are bound to POLN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr422433972243478-5'-UTR,intron-Distal3.496605.46476K562AQR
chr422432152243271-5'-UTR,intron-Distal,intron-Proximal4.255577.26133HepG2PRPF8
chr422433732243456-5'-UTR,intron-Distal3.280814.41086K562DROSHA
chr422432572243305-5'-UTR,intron-Distal4.233434.11693K562BUD13
chr422432372243301-5'-UTR,intron-Distal,intron-Proximal3.140763.65536K562SRSF1
chr422433332243371-5'-UTR,intron-Distal4.651974.82934K562RBM15
chr422434822243588-5'-UTR,intron-Distal,intron-Proximal5.647048.34710K562AQR
chr422437142243780-5'-UTR,intron-Distal4.359799.78712K562AQR
chr422436402243744-5'-UTR,intron-Distal,intron-Proximal4.053147.75469HepG2EFTUD2
chr422429722243004-intron-Distal3.288113.47285K562PRPF8
chr422424652242559-CDS,intron-Distal,intron-Proximal3.564425.56491HepG2BCLAF1
chr422424982242587-CDS,intron-Distal,intron-Proximal4.131087.36824K562RBM15
chr422427822242836-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.7892310.80251K562U2AF2
chr422391362239263-intron-Distal5.5020213.02909K562PTBP1
chr422427832242838-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.747895.47569HepG2U2AF2
chr422349572235116-intron-Distal5.025558.06346K562KHSRP
chr422391532239256-intron-Distal5.5623910.89838HepG2PTBP1
chr422379152237981-CDS,intron-Distal,intron-Proximal4.222854.15208K562RBM15
chr422336802233740-CDS,intron-Distal4.310054.04372HepG2BCLAF1
chr422427852242836-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.492344.11428K562U2AF1
chr422424732242579-CDS,intron-Distal,intron-Proximal3.847164.82429K562TARDBP
chr422424822242613-CDS,intron-Distal,intron-Proximal3.741183.01412K562SAFB2
chr422379532238056-CDS,intron-Distal,intron-Proximal3.800624.76554HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLN is not available on ENCORE database.

  • 13 RBPs can affect the levels of POLN.  








The Knockdown/knockout RNA-Seq assay for POLN is not available on ENCORE database.





13 RBPs can affect the gene expression of POLN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLNENSG00000130997.1221.951704.554402.268902.529901.77700HepG2ASCC1
POLNENSG00000130997.1222.456204.815902.221102.592901.97270HepG2EIF4A3
POLNENSG00000130997.1240.7917013.111101.637402.883201.62890K562ABCF1
POLNENSG00000130997.1256.1796012.410102.178405.248604.03570K562BOP1
POLNENSG00000130997.1236.6670010.946601.743902.870701.40520K562CKAP4
POLNENSG00000130997.1241.8309013.196301.664303.088202.25920K562CPSF6
POLNENSG00000130997.1256.0835013.425302.062505.074803.91030K562FMR1
POLNENSG00000130997.1251.7150011.378402.184205.368504.04990K562FTO
POLNENSG00000130997.1219.373204.675302.050801.966601.45210K562HNRNPC
POLNENSG00000130997.1240.945709.553902.099503.760602.78990K562PCBP3
POLNENSG00000130997.1230.413307.325602.053602.173201.46350K562POLR2G
POLNENSG00000130997.1244.7555013.461901.733103.013302.16120K562PUF60
POLNENSG00000130997.1240.3103014.305301.494502.991801.87780K562PUM1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLN is not available on ENCORE database.






No RBPs affect the alternative splcing events of POLN on ENCORE database.





The Knockdown/knockout RNA-Seq assay for POLN is not avaliable on ENCORE database.