SRRT

General Information

Gene Name : SRRT
Gene ID : ENSG00000087087.19
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SRRT)

Not Available

Antibody Validation

Bethyl Labs: A304-551A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SRRT	ENSG00000087087.19	43.56	81.71	62.63	ENCSR000AEF
HepG2	SRRT	ENSG00000087087.19	140.86	84.05	112.46	ENCSR985KAT
K562	SRRT	ENSG00000087087.19	104.83	96.01	100.42	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SRRT		A304-551A	1				BGHcLV45-63, Submitted, ENCORE2	BGKcLV44-63, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
SRRT	K562	CRISPR	BGKcLV37-45,BGKcLV37-46	BGKcLV37-1,BGKcLV37-2	too many bands,	NotSatisfied	ENCORE2
SRRT	K562	CRISPR	SRRT-BGKcLV44-63,SRRT-BGKcLV44-64	NT-BGKcLV44-1,NT-BGKcLV44-2	62.8,63.9053	Submitting	ENCORE2
SRRT	K562	CRISPR	BGKcLV44-65,BGKcLV44-66	BGKcLV44-1,BGKcLV44-2		NotSatisfied	ENCORE2
SRRT	HepG2	CRISPR	BGHcLV36-43,BGHcLV36-44	BGHcLV36-1,BGHcLV36-2	too many bands ,	NotSatisfied	ENCORE2
SRRT	HepG2	CRISPR	SRRT-BGHcLV45-63,SRRT-BGHcLV45-64	NT-BGHcLV45-1,NT-BGHcLV45-2	93.9,91.2	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SRRT	Product_ID: A304-551A Lot_ID: 1 Source: Bethyl Labs Target Name: SRRT-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SRRT is not avaliable on ENCORE database.

Proteins bound to RNA

SRRT RNA is bound by 40 proteins.

CanvasJS.com

eCLIP assay for SRRT is not avaliable on ENCORE database.

40 proteins are bound to SRRT RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr7	100480968	100481038	+	intron-Distal	5.40212	78.90724	K562	PTBP1
chr7	100480904	100481035	+	intron-Distal	5.64809	52.17903	HepG2	PTBP1
chr7	100482838	100482978	+	CDS	5.42914	42.74352	K562	UCHL5
chr7	100481045	100481111	+	intron-Distal	4.91721	38.31390	K562	PTBP1
chr7	100480745	100480815	+	intron-Distal,intron-Proximal	5.92325	36.43795	K562	PTBP1
chr7	100485642	100485707	+	CDS,intron-Proximal	5.04101	34.07055	K562	AQR
chr7	100485486	100485553	+	intron-Proximal	5.50422	34.02354	K562	AQR
chr7	100482083	100482172	+	CDS	4.82675	30.60281	K562	UCHL5
chr7	100480898	100480968	+	intron-Distal	4.93780	29.93397	K562	PTBP1
chr7	100479041	100479079	+	intron-Proximal	4.65718	29.34311	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 223 entries

eCLIP assay for SRRT is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SRRT is not available on ENCORE database.
115 RBPs can affect the levels of SRRT.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SRRT is not available on ENCORE database.

115 RBPs can affect the gene expression of SRRT :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SRRT	ENSG00000087087.14	2590.30560	1191.59570	1.12010	48.69330	47.24630	HepG2	SRSF1
SRRT	ENSG00000087087.14	8771.23320	3781.95050	1.21350	34.19070	32.24050	K562	PUS1
SRRT	ENSG00000087087.14	4098.57380	1817.90220	1.17270	27.20400	24.86090	K562	PRPF8
SRRT	ENSG00000087087.14	1269.81620	2800.13640	-1.14090	26.32540	24.67660	HepG2	RPLP0
SRRT	ENSG00000087087.14	2600.62550	1424.72590	0.86810	23.96530	21.60710	K562	EIF3G
SRRT	ENSG00000087087.14	7578.09050	4945.70090	0.61560	21.38180	19.73350	K562	DDX47
SRRT	ENSG00000087087.14	3410.16500	1869.92890	0.86680	20.78850	18.86490	K562	SRSF1
SRRT	ENSG00000087087.14	468.73930	1223.97160	-1.38470	19.07370	16.77410	K562	G3BP2
SRRT	ENSG00000087087.14	1910.48310	2772.99190	-0.53750	17.18840	16.11600	HepG2	ZNF622
SRRT	ENSG00000087087.14	4801.58840	2892.16980	0.73130	17.72290	15.68240	K562	SYNCRIP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 137 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SRRT is not available on ENCORE database.

23 RBPs can affect the splicing of SRRT :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	SRRT	ENSG00000087087.14	chr7	+	100480385	100480711	100479673	100479862	100481690	100481860	0.64600	0.00000	included	HepG2	U2AF2
SE	SRRT	ENSG00000087087.14	chr7	+	100479279	100479426	100478905	100479034	100479673	100479862	-0.33200	0.00000	excluded	HepG2	U2AF2
SE	SRRT	ENSG00000087087.14	chr7	+	100480385	100480711	100479673	100479862	100481690	100481860	0.17100	0.00000	included	K562	AQR
SE	SRRT	ENSG00000087087.14	chr7	+	100478316	100478390	100473193	100473333	100478905	100479034	0.10700	0.00001	included	K562	AQR
SE	SRRT	ENSG00000087087.14	chr7	+	100480385	100480711	100479673	100479862	100481690	100481860	-0.18700	0.00206	excluded	K562	HNRNPA1
A3SS	SRRT	ENSG00000087087.14	chr7	+	100485662	100485764	100485674	100485764	100485323	100485480	-0.30400	0.00029	shorter	K562	RBM22
A3SS	SRRT	ENSG00000087087.14	chr7	+	100485638	100485764	100485674	100485764	100485323	100485480	0.19500	0.00000	longer	K562	AQR
A3SS	SRRT	ENSG00000087087.14	chr7	+	100482789	100482991	100482836	100482991	100482543	100482661	0.07500	0.00000	longer	K562	AQR
A3SS	SRRT	ENSG00000087087.14	chr7	+	100485662	100485764	100485674	100485764	100485323	100485480	-0.20000	0.00000	shorter	K562	AQR
A5SS	SRRT	ENSG00000087087.14	chr7	+	100482543	100482712	100482543	100482661	100482836	100482991	0.08300	0.00000	longer	K562	AQR

Showing 1 to 10 of 38 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SRRT

General Information

Functions

Localization

Domains (AlphaFold: SRRT)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SRRT is not avaliable on ENCORE database.

40 proteins are bound to SRRT RNA:

eCLIP assay for SRRT is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SRRT is not available on ENCORE database.

115 RBPs can affect the gene expression of SRRT :

The Knockdown/knockout RNA-Seq assay for SRRT is not available on ENCORE database.

23 RBPs can affect the splicing of SRRT :

The Knockdown/knockout RNA-Seq assay for SRRT is not avaliable on ENCORE database.