POLR1B

General Information

Gene Name : POLR1B
Gene ID : ENSG00000125630.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLR1B)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLR1B	ENSG00000125630.15	23.90	22.88	23.39	ENCSR000AEF
HepG2	POLR1B	ENSG00000125630.15	33.09	35.68	34.39	ENCSR985KAT
K562	POLR1B	ENSG00000125630.15	28.63	27.02	27.82	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLR1B is not avaliable on ENCORE database.

Proteins bound to RNA

POLR1B RNA is bound by 11 proteins.

CanvasJS.com

eCLIP assay for POLR1B is not avaliable on ENCORE database.

11 proteins are bound to POLR1B RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	113300203	113300315	+	5'-UTR,CDS,intron-Proximal	5.12832	25.92827	HepG2	PRPF8
chr2	113322016	113322119	+	3'-UTR,CDS,intron-Distal,intron-Proximal	6.94549	22.91628	HepG2	PRPF8
chr2	113300214	113300313	+	5'-UTR,CDS,intron-Proximal	3.84532	8.25843	K562	PRPF8
chr2	113310393	113310437	+	intron-Distal,intron-Proximal	5.35334	8.03507	K562	AQR
chr2	113300044	113300126	+	5'-UTR,CDS	3.49490	7.64752	HepG2	SRSF1
chr2	113300142	113300292	+	5'-UTR,CDS,intron-Proximal	4.70613	7.46830	HepG2	SRSF1
chr2	113306862	113306976	+	3'-UTR,5'-UTR,CDS,intron-Distal	3.56734	7.01246	HepG2	BCLAF1
chr2	113304637	113304702	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.97391	6.00726	K562	YBX3
chr2	113300031	113300134	+	5'-UTR,CDS	3.00746	5.93610	HepG2	NCBP2
chr2	113300255	113300323	+	intron-Proximal	4.25267	5.92879	HepG2	RBM22
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 29 entries

eCLIP assay for POLR1B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLR1B is not available on ENCORE database.
99 RBPs can affect the levels of POLR1B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for POLR1B is not available on ENCORE database.

99 RBPs can affect the gene expression of POLR1B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLR1B	ENSG00000125630.11	1776.68340	975.31510	0.86510	24.85280	23.33080	HepG2	UTP3
POLR1B	ENSG00000125630.11	705.56800	1327.74210	-0.91210	23.37390	21.36110	K562	MTPAP
POLR1B	ENSG00000125630.11	1618.58200	923.07830	0.81010	18.52780	17.07040	K562	FXR1
POLR1B	ENSG00000125630.11	472.56310	1048.97780	-1.15040	16.06420	14.71420	HepG2	EIF2S1
POLR1B	ENSG00000125630.11	1261.97930	2049.44730	-0.69950	16.01220	14.49570	K562	EIF2S2
POLR1B	ENSG00000125630.11	643.76110	1259.42990	-0.96820	13.65090	11.32410	K562	UCHL5
POLR1B	ENSG00000125630.11	494.88210	929.14340	-0.90880	12.13320	10.93500	HepG2	HNRNPA1
POLR1B	ENSG00000125630.11	1041.13120	1564.31320	-0.58740	12.08590	10.71640	K562	UPF1
POLR1B	ENSG00000125630.11	901.55780	1387.37900	-0.62190	11.93450	10.66310	HepG2	SRSF7
POLR1B	ENSG00000125630.11	797.69280	1338.54450	-0.74680	11.66950	9.82280	K562	WDR3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 117 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLR1B is not available on ENCORE database.

9 RBPs can affect the splicing of POLR1B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	-0.19200	0.00000	0.00019	excluded	HepG2	SRSF1
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	0.34200	0.00000	0.00001	included	K562	HNRNPC
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	0.11000	0.00006	0.04074	included	K562	PUM2
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	0.10400	0.00008	0.03044	included	K562	PUM1
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	-0.20700	0.00012	0.02743	excluded	HepG2	TIA1
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	-0.18900	0.00022	0.01561	excluded	HepG2	PTBP1
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	0.12400	0.00042	0.06224	included	K562	ZC3H8
SE	POLR1B	ENSG00000125630.11	chr2	+	113303407	113303499	113299765	113300248	113304588	113304756	0.25900	0.00275	0.08363	included	HepG2	HNRNPC
SE	POLR1B	ENSG00000125630.11	chr2	+	113315486	113315658	113310221	113310393	113316869	113317151	-0.14200	0.00429	0.05537	excluded	K562	PUS1
SE	POLR1B	ENSG00000125630.11	chr2	+	113316869	113317151	113310221	113310393	113321942	113322076	-0.09700	0.00990	0.08060	excluded	K562	AQR

Showing 1 to 10 of 11 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLR1B

General Information

Functions

Localization

Domains (AlphaFold: POLR1B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLR1B is not avaliable on ENCORE database.

11 proteins are bound to POLR1B RNA:

eCLIP assay for POLR1B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLR1B is not available on ENCORE database.

99 RBPs can affect the gene expression of POLR1B :

The Knockdown/knockout RNA-Seq assay for POLR1B is not available on ENCORE database.

9 RBPs can affect the splicing of POLR1B :

The Knockdown/knockout RNA-Seq assay for POLR1B is not avaliable on ENCORE database.